3HAXA

Crystal structure of a substrate-bound gar1-minus h/aca rnp from pyrococcus furiosus
Total Genus 95
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
329
structure length
329
Chain Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLWEK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural mechanism of substrate RNA recruitment in H/ACA RNA-guided pseudouridine synthase.
pubmed doi rcsb
molecule tags Isomerase/biosynthetic protein/rna
source organism Pyrococcus furiosus
molecule keywords Probable tRNA pseudouridine synthase B
total genus 95
structure length 329
sequence length 329
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2009-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 3haxA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3haxA02
2I82A 3ZV0C 2RFKA 1KSLA 4LGTA 3MQKA 2APOA 3LWQA 1V9FA 1R3FA 1SGVA 3LWRA 3DH3A 2ISTA 1ZE1A 4LABA 2HVYA 3LWVA 1ZL3A 3HJWA 3HAXA 3LWOA 1KSVA 1V9KA 2AUSA 1K8WA 2EY4A 2AB4A 3LWPA 1XPIA 1PRZA 1R3EA 3UAIA 1ZE2A 3U28A 1QYUA 3HJYA 1KSKA
chains in the Genus database with same CATH superfamily
2I82A 1IQ8A 1WXXA 2APOA 2ISTA 1ZE1A 4TZ4C 1ZL3A 1T5YA 2AS0A 3VSEA 3HAXA 3M6XA 1XPIA 1XNEA 3D79A 1SI7A 2CWWA 2CX0A 1J2BA 3ZV0C 1SZWA 1TE7A 3M6WA 1R3FA 2B78A 2P38A 3C0KA 3IUWA 2HVYA 1IT7A 3LWOA 1UOYA 2AUSA 2EY4A 1R3EA 1WXWA 3HJYA 1KSKA 3M6UA 2DP9A 4CI2B 4DMGA 2RFKA 1V9FA 1Q7HA 3DH3A 2Z0TA 1SB7A 4LABA 1ZS7A 3LWVA 1ZBOA 4Q1TA 1IT8A 1Z2ZA 3HJWA 4CI1B 2Q07A 2AB4A 2ANEA 3UAIA 3U28A 1ZE2A 3M4XA 1QYUA 3M6VA 1S04A 2FRXA 2J5VA 2E5OA 1KSLA 4LGTA 3MQKA 3LWQA 1SGVA 3LWRA 3M65A 2CX1A 1WK2A 4CI3B 3LJCA 3LDFA 2J5TA 1KSVA 1V9KA 1SQWA 1K8WA 2KKUA 3LWPA 1PRZA
chains in the Genus database with same CATH topology
2I82A 3ZV0C 2RFKA 1SI7A 1KSLA 4LGTA 3MQKA 2APOA 3M6WA 3LWQA 1R3FA 1SZWA 1V9FA 1SGVA 3LWRA 3DH3A 1SB7A 1ZE1A 2ISTA 2HVYA 4LABA 3LWVA 1ZL3A 1Z2ZA 3HJWA 3HAXA 3M6XA 3LWOA 1KSVA 1V9KA 1UOYA 2AUSA 1K8WA 2EY4A 2AB4A 3LWPA 1XPIA 1PRZA 1R3EA 3UAIA 1ZE2A 3U28A 3M4XA 1QYUA 3HJYA 3M6VA 1KSKA 3M6UA 2FRXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I82 A;  3ZV0 C;  2RFK A;  1KSL A;  4LGT A;  3MQK A;  2APO A;  3LWQ A;  1V9F A;  1R3F A;  1SGV A;  3LWR A;  3DH3 A;  2IST A;  1ZE1 A;  4LAB A;  2HVY A;  3LWV A;  1ZL3 A;  3HJW A;  3HAX A;  3LWO A;  1KSV A;  1V9K A;  2AUS A;  1K8W A;  2EY4 A;  2AB4 A;  3LWP A;  1XPI A;  1PRZ A;  1R3E A;  3UAI A;  1ZE2 A;  3U28 A;  1QYU A;  3HJY A;  1KSK A; 
#chains in the Genus database with same CATH topology
 2I82 A;  1IQ8 A;  1WXX A;  2APO A;  2IST A;  1ZE1 A;  4TZ4 C;  1ZL3 A;  1T5Y A;  2AS0 A;  3VSE A;  3HAX A;  3M6X A;  1XPI A;  1XNE A;  3D79 A;  1SI7 A;  2CWW A;  2CX0 A;  1J2B A;  3ZV0 C;  1SZW A;  1TE7 A;  3M6W A;  1R3F A;  2B78 A;  2P38 A;  3C0K A;  3IUW A;  2HVY A;  1IT7 A;  3LWO A;  1UOY A;  2AUS A;  2EY4 A;  1R3E A;  1WXW A;  3HJY A;  1KSK A;  3M6U A;  2DP9 A;  4CI2 B;  4DMG A;  2RFK A;  1V9F A;  1Q7H A;  3DH3 A;  2Z0T A;  1SB7 A;  4LAB A;  1ZS7 A;  3LWV A;  1ZBO A;  4Q1T A;  1IT8 A;  1Z2Z A;  3HJW A;  4CI1 B;  2Q07 A;  2AB4 A;  2ANE A;  3UAI A;  3U28 A;  1ZE2 A;  3M4X A;  1QYU A;  3M6V A;  1S04 A;  2FRX A;  2J5V A;  2E5O A;  1KSL A;  4LGT A;  3MQK A;  3LWQ A;  1SGV A;  3LWR A;  3M65 A;  2CX1 A;  1WK2 A;  4CI3 B;  3LJC A;  3LDF A;  2J5T A;  1KSV A;  1V9K A;  1SQW A;  1K8W A;  2KKU A;  3LWP A;  1PRZ A; 
#chains in the Genus database with same CATH homology
 2I82 A;  3ZV0 C;  2RFK A;  1SI7 A;  1KSL A;  4LGT A;  3MQK A;  2APO A;  3M6W A;  3LWQ A;  1R3F A;  1SZW A;  1V9F A;  1SGV A;  3LWR A;  3DH3 A;  1SB7 A;  1ZE1 A;  2IST A;  2HVY A;  4LAB A;  3LWV A;  1ZL3 A;  1Z2Z A;  3HJW A;  3HAX A;  3M6X A;  3LWO A;  1KSV A;  1V9K A;  1UOY A;  2AUS A;  1K8W A;  2EY4 A;  2AB4 A;  3LWP A;  1XPI A;  1PRZ A;  1R3E A;  3UAI A;  1ZE2 A;  3U28 A;  3M4X A;  1QYU A;  3HJY A;  3M6V A;  1KSK A;  3M6U A;  2FRX A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...