4LR2A

Crystal structure of human enpp4 (apo)
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
Knots found
sequence length
379
structure length
379
Chain Sequence
LPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Bis(5'-adenosyl)-triphosphatase ENPP4
total genus 128
structure length 379
sequence length 379
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.6.1.29: Bis(5'-adenosyl)-triphosphatase.
pdb deposition date 2013-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.180 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Gyrase A; domain 2 4lr2A02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4lr2A01
3MK2A 3BDGB 3NVLA 1Y7AA 4FDJA 4QAXA 4CXKA 4YR1A 1EW8A 5EGEA 3UN2A 1KH9A 4ZG7A 1KHNA 1SHNA 4NWXA 1EJJA 4ZG9A 5LIAA 2GSNA 1E1ZP 3WAYA 2GLQA 3T02A 4CYSA 4ZG6A 5GRRA 1EW9A 3NKNA 2IFYA 2VQRA 2IUCA 3SZZA 1ALKA 4NWJA 1AUKA 4KM4A 1E33P 4LR2A 3LXQA 5IJSA 5TJ3A 3MK1A 5LRMA 2D1GA 1ANIA 3NKRA 4GTZA 2RH6A 4TN0A 3CMRA 3WAVA 1KH7A 2W8SA 4CXUA 5LQQA 1ANJA 3NKMA 4FDIA 3TX0A 3MK0A 2X98A 1AJBA 3UN5A 1URAA 4GTWA 4LRAA 1HJKA 5AJ9A 1EW2A 3DYCA 2W8DA 5DLVA 4CYRA 3UNYA 5L0BA 4LR9A 1KH4A 2QZUA 3IDDA 3DPCA 3T01A 1SHQA 5EGHA 1EI6A 3SZYA 4CXSA 3BDGA 1ELYA 4LREA 3NKOA 4GTYA 1EQJA 2W5XA 2W5SA 4LRDA 2XRGA 5KXAA 3E2DA 4KAYA 4LR8A 5HRTA 1K7HA 1URBA 1AJAA 3OT9A 1ALJA 1AJDA 3BDHA 1KH5A 4LRCA 4LQYA 3NKQA 4UORA 3M8YA 3WAXA 3UN3A 4UPIA 5C66A 5GOVA 2ANHA 4LR7A 4LRFA 4N7TA 3T00A 1E3CP 1ZEFA 1N2LA 4KJDA 2W5TA 1FSUA 3WBHA 3BDFA 4LRBA 3Q3QA 3M8ZA 1O98A 5L0EA 4UOPA 1ED9A 1ZEBA 5K4PA 5LRNA 2W5RA 3M7VA 1HDHA 2IUCB 1ELZA 3TWZA 1KHLA 5DLWA 2GSOA 1HQAA 3B5QA 2W5VA 1B8JA 2W5WA 2GA3A 1KHJA 4GTXA 4KJGA 1AJCA 1ALHA 1ELXA 2W5QA 4ZGAA 1ED8A 3UO0A 3TG0A 1N2KA 3NKPA 3ED4A 3IGZB 3KD8A 1Y6VA 4MHXA 1KHKA 5INHA 4MY4A 2XR9A 1E2SP 5L0KA 4MIVA 5IJQA 4UOOA 3M8WA 2GSUA 4KAVA 4UPLA 2G9YA 1ALIA 3A52A 5DLTA 3WAWA 4UPKA 4UPHA 2ZKTA 1ZEDA 1P49A 1O99A 3IGYB 4B56A
chains in the Genus database with same CATH superfamily
1VLOA 3GEEA 4BBRK 3MK2A 4MEYA 1O26A 4CXKA 4A93K 5EGEA 4ZG7A 1SHNA 1EJJA 3GTJC 3PO3K 2R93K 1TWHK 1E1ZP 3M3YK 3WAYA 2R93A 1TWHA 3S14C 5GRRA 4QJVA 5IYDC 5IOSA 5IOQA 4Y7NC 5IOTA 3S15K 2XCOA 3AD9C 2NVTC 3RZDK 5IJSA 3GTOA 4C3JC 4TN0A 3CMRA 2W8SA 3NKMA 2Y0SD 2O5JA 3G4AA 3S2DC 1J6XA 1ZXOA 4C3HC 1TWFK 1TWFA 1URAA 5JFEA 4LOWA 4GTWA 4BLBA 3DYCA 2W8DA 2NVXC 1TWGK 5C4JK 3UNYA 5L0BA 4LR9A 4BY1C 4PABA 3HOVK 2JA6A 2W7VA 3V4GA 3I4NK 3DPCA 4AYBL 3GTPK 3GTLC 1SHQA 4CXSA 3GTMC 3GTPA 1ELYA 3NKOA 3GTQK 4QIWD 3H3VD 3OPFA 1EQJA 2W5XA 1R9TC 4YG2A 3N0BA 3GTQA 2R92C 3G4CA 1YCLA 4LR8A 3S1QK 4A3EK 3K7AC 3NKQA 1IS1A 3WAXA 1O24A 1WCMA 1IE0A 3S0XA 2P8TA 3GTOC 2PA8L 2ANHA 4N7TA 1PJ5A 5C4XC 5CJ9A 4A3MK 2W5TA 1YX2A 3A8IA 3BP8C 3GDZA 1F7UA 4A3IC 5L0EA 1EK8A 4KB4A 3S16C 1ED9A 2E2HK 4JK1A 2RGRA 3AD7C 2JA7A 4QJVB 2JA5K 1Y1VC 1ELZA 3GTGC 2JA5A 5IYCC 2PPBA 2GSOA 2GA3A 1KHJA 4KJGA 4WJ4A 2ZUFA 2E2IK 3UO0A 1IW7A 2ZUEA 3NKPA 1HI9A 3LPXA 4A3LK 3AQOA 1Y6VA 3HOWC 1KHKA 3H0GA 4G7ZA 3S2HC 5FJ8K 2VUMC 5IP7C 5L0KA 4MIVA 1SFOK 5IJQA 4UOOA 1EQRA 2V6UA 4XLNA 2GSUA 3CQZC 1SFOA 1RU0A 1JVIA 3S1MC 1Y1WA 1XZPA 4BY7C 1BS2A 2A6HA 1P49A 4BXXC 1WORA 4P9SA 4YR1A 4QAXA 1L0WA 1EW8A 2JA7C 3FOEA 1KHNA 4AH6A 5LIAA 1VJEA 3S17K 1WOPA 4GTDA 5M5WK 1F7VA 1VH2A 1O27A 3NKNA 1I3QC 2IFYA 4KB2A 2R7ZC 4BKWA 4MEXA 4BBSC 2WAQD 2NVYA 2A68A 5TJ3A 5LRMA 3GTKA 4A3FK 1EH1A 1I6HK 5IYDK 3WAVA 1O2AA 1KH7A 3N3YA 1K83A 4CXUA 1DCHA 1AJBA 5JVOA 5IP9K 4LK0A 3IPJA 4C3JK 4Q5SA 1I50C 1PJ7A 3S1NC 4AYBD 5D4DA 4G7HA 3S2DK 4GTEA 1WQHA 4C3HK 3DXJA 2ZFZA 4CYRA 5IORA 3HOYC 1TWCC 3T01A 4WJ3M 5M3FK 3SZYA 4A3JK 4A3GK 4LREA 5L46A 2E2JK 3ADAC 3AH5A 2W5SA 2CFAA 4LRDA 3E2DA 2JA8K 4XSZA 1K7HA 2PMZL 4KDDA 1AJAA 1AJDA 1KH5A 3GTLK 4LLGA 3ERED 3UN3A 4C3IC 3L4JA 1R9TK 1XZPB 2GAHC 4O2DA 1E3CP 4KM8A 1X31C 3HOZC 2NVQC 1WQGA 4G0WA 3I4MC 3WBHA 1BDFA 3BDFA 4LRBA 1ZYRA 4G0VA 1HQMA 1TWGA 1WOSA 5IYBK 3LAJA 3HOXK 3TFHA 4UOPA 4KMUA 3HOUK 5K4PA 4GTBA 5LRNA 4C2MK 3TWZA 3PO3C 2R93C 1TWHC 3M3YC 1WSVA 3PO2K 4GFQA 4X6AK 4A3IK 5DLWA 2JH3A 3B5QA 1B8JA 2W5WA 3S15C 4GTFA 4GTXA 5C3EK 1ELXA 4YFKA 1UV7A 1Y1VK 3RZDC 1TWAK 3EQLA 3FKIK 5IYCK 3RZOC 3IGZB 1YNJA 1TWAA 3AQPA 3TFJA 1DCPA 4LJZA 4OIRA 1F93A 4KMDA 1WIHA 4MY4A 3M4OK 5C44C 1GE9A 1TWFC 1VGXA 2PHCB 4OIPA 4A3CK 3HKZL 1YNNA 2B63K 2E2HA 3HOWK 4UPKA 2ZKTA 2P5MA 1TWGC 1O99A 2JA6C 4B56A 5M5XK 4GT9A 3HOVC 3CQZK 4FDJA 3I4NC 2CFAB 3GTPC 1KH9A 4NWXA 1JQWA 3S1MK 4A3BK 4Q4ZA 4WILA 4LK1A 3GTQC 2E2IA 3T02A 1VRQC 1ZBSA 2GLQA 4DDQA 4BXXK 1J6WA 2VQRA 3S1QC 2IUCA 4Y52C 1ALKA 3TFIA 4NWJA 1WCMC 1AUKA 4KM4A 1E33P 1B4AA 3MK1A 1ANIA 3NKRA 2RH6A 1INNA 2YU9K 5LQQA 1ANJA 1J6VA 3TX0A 2YU9A 3MK0A 2X98A 4GTAA 1EFWA 5HL8A 4KARA 2E2HC 2GAGC 2JA5C 2XCQA 3CAGA 5DLVA 4XCHA 1DCOA 4KMHA 1KH4A 3IDDA 3GEHA 2PMZD 1EI6A 5EGHA 3GTJK 4P5BA 3BDGA 3LAPA 4GTYA 3GTJA 5FLMC 3S14K 1XXCA 5KXAA 1TWCK 4Y7NK 2O5IA 5HRTA 4A3LC 3H0GC 4NOIA 3WODA 3OT9A 4XSXA 3BDHA 1WOOA 4LRCA 4MQ9A 2KWAA 2Y3PA 3S1RC 2NVTK 4UORA 1V5VA 4A3KC 1SFOC 4M1XA 1IQ0A 3T00A 4LR7A 2V6SA 3TTGA 4YFXA 1ZEFA 3HXAA 3JSTA 1Y1WC 4OINA 4KJDA 1FSUA 4A3DC 3AD8C 2V6TA 2A69A 3M8ZA 3MMLB 4KN4A 1ZEBA 2W5RA 1XXAA 1PJ6A 1JOEA 2NVQK 3L4KA 2IUCB 2NVXK 3FHZA 3I4MK 3S17C 4BY1K 4G0UA 1HQAA 2A6EA 2PA8D 3GTMK 4ZGAA 3GTLA 1O2BA 2NVYC 1USMA 3GTKC 5TMCA 3GTMA 1C0AA 1O2FB 3ED4A 2R92K 3KD8A 4A3FC 4KMAA 1K83C 1R9TA 1I6HC 1XZQA 3K7AK 2R92A 4MHXA 4KAWX 3GSIA 3HKZD 5INHA 2WB1L 2XR9A 3GTOK 4BBRC 3RZOK 3M8WA 5IP9C 2G9YA 1ALIA 1B4BA 3WAWA 5C4XK 4A93C 3VA7A 1ZVUA 4FM9A 2WAQL 5C44K 4J3NA 1O25A 3IGYB 3S16K 3BDGB 3NVLA 1Y7AA 4GZYA 4ZG9A 3UN2A 4KC6A 5TMFA 4A3JC 1DD5A 2GSNA 3GTGK 3A8JA 4A3GC 1Y1VA 4GTCA 1ISEA 4KATA 2E2JC 3GTGA 2JA6K 3FKIA 4CYSA 4ZG6A 3OEPA 2JA8C 1EW9A 1I6VA 3SZZA 5CHPA 4GTLA 4LR2A 3LXQA 4ILDA 4OIOA 2D1GA 1USOA 4GTZA 4KN7A 4Y52K 1WSRA 4ZH4A 2XCRB 3S2HK 2B63A 4FDIA 1WCMK 2VUMK 5C4JC 5IP7K 3N0CA 2VUMA 3UN5A 5IYBC 3HOXC 1IBAA 4RMFA 3HOUC 4LRAA 2Y0SL 3CQZA 1SMYA 1HJKA 5AJ9A 4C2MC 5E68A 4BY7K 1EW2A 4OIQA 3PO2C 4X6AC 4C45A 2QZUA 4P5AA 4A3EC 2D6FC 2JA7K 1IL2A 4BLAA 5C3EC 1XZQB 1XPPA 1TWAC 1BJTA 2CW0A 3FKIC 3FOFA 2XRGA 5M3MK 4KAYA 1I3QK 3QX3A 1URBA 1I3QA 1ALJA 4FZBA 2R7ZK 4A3MC 4BBSK 3BP3A 3GEIA 4LQYA 4QIWL 3H3VL 2R7ZA 3M8YA 3M4OC 4UPIA 5C66A 5FLMK 5GOVA 1O29A 4LRFA 4A3CC 3H0GK 4PAAA 2BE5A 1N2LA 2B63C 3S1RK 3NUHA 3Q3QA 2EBBA 4A3KK 1O98A 1I50K 3S1NK 1Y1WK 3M7VA 4KM9A 2E2IC 1HDHA 1I50A 4A3BC 1F9NA 4A3DK 1KHLA 3HOYK 4G7OA 4KASA 2W5VA 1XXBA 1TWCA 2FQTA 1AJCA 1ALHA 2W5QA 3TG0A 1J98A 4YFNA 1ED8A 1AB4A 3A8KA 1N2KA 1O28A 2WB1D 1WQFA 2YU9C 1ZQ1C 2NVYK 4C3IK 3GTKK 1BGWA 4XLPA 2FQOA 1E2SP 3OREA 3BUEA 4KAVA 4UPLA 3A52A 5DLTA 5M5YK 1K83K 3HOZK 4UPHA 3GIRA 1G51A 1ZEDA 2NVXA 1KQ4A
chains in the Genus database with same CATH topology
3MK2A 1O26A 4CXKA 5EGEA 4ZG7A 1SHNA 1EJJA 1E1ZP 3WAYA 2R93A 1TWHA 5GRRA 5IOSA 5IOQA 5IOTA 2XCOA 5IJSA 3GTOA 4C3JC 4TN0A 3CMRA 2W8SA 3NKMA 3G4AA 4C3HC 1ZXOA 1TWFA 1URAA 5JFEA 4GTWA 4BLBA 3DYCA 2W8DA 3UNYA 5L0BA 4LR9A 2JA6A 3V4GA 3DPCA 1SHQA 4CXSA 3GTPA 1ELYA 3NKOA 1EQJA 3OPFA 2W5XA 3GTQA 3N0BA 4LR8A 3G4CA 3NKQA 1IS1A 3WAXA 1O24A 1WCMA 3S0XA 2ANHA 4N7TA 5CJ9A 2W5TA 5L0EA 1EK8A 4KB4A 1ED9A 2RGRA 2JA7A 1ELZA 2JA5A 2GSOA 2GA3A 1KHJA 4KJGA 3UO0A 3NKPA 3LPXA 3AQOA 1Y6VA 1KHKA 3H0GA 5L0KA 4MIVA 5IJQA 4UOOA 2GSUA 1SFOA 1Y1WA 1P49A 4YR1A 4QAXA 1EW8A 3FOEA 1KHNA 5LIAA 4GTDA 1O27A 3NKNA 2IFYA 4KB2A 4BKWA 2NVYA 5TJ3A 5LRMA 3GTKA 1EH1A 3WAVA 1O2AA 1KH7A 3N3YA 1K83A 4CXUA 1AJBA 5JVOA 4GTEA 1WQHA 2ZFZA 4CYRA 5IORA 3T01A 3SZYA 4LREA 3AH5A 4LRDA 2CFAA 2W5SA 3E2DA 1K7HA 4KDDA 1AJAA 1AJDA 1KH5A 3ERED 3UN3A 4C3IC 3L4JA 1E3CP 4KM8A 1WQGA 4G0WA 3WBHA 3BDFA 4LRBA 4G0VA 1TWGA 3LAJA 4UOPA 5K4PA 4GTBA 5LRNA 3TWZA 4GFQA 5DLWA 2JH3A 3B5QA 1B8JA 2W5WA 4GTFA 4GTXA 1ELXA 3IGZB 1TWAA 3AQPA 4KMDA 1WIHA 4MY4A 1GE9A 2PHCB 2E2HA 4UPKA 2ZKTA 2P5MA 1O99A 4B56A 4GT9A 4FDJA 2CFAB 1KH9A 4NWXA 2E2IA 2GLQA 3T02A 1ZBSA 4DDQA 2VQRA 2IUCA 1ALKA 4NWJA 1AUKA 4KM4A 1E33P 1B4AA 3MK1A 1ANIA 3NKRA 2RH6A 5LQQA 1ANJA 3TX0A 2YU9A 3MK0A 2X98A 4GTAA 4KARA 2XCQA 3CAGA 5DLVA 4KMHA 1KH4A 3IDDA 5EGHA 1EI6A 4P5BA 3BDGA 3LAPA 4GTYA 3GTJA 5KXAA 1XXCA 5HRTA 3OT9A 3BDHA 4LRCA 2KWAA 2Y3PA 4UORA 4M1XA 3T00A 4LR7A 1ZEFA 4KJDA 1FSUA 3M8ZA 3MMLB 1ZEBA 2W5RA 1XXAA 3L4KA 2IUCB 3FHZA 4G0UA 1HQAA 4ZGAA 3GTLA 1O2BA 3GTMA 3ED4A 3KD8A 4KMAA 1R9TA 2R92A 4MHXA 4KAWX 5INHA 2XR9A 3M8WA 2G9YA 1ALIA 1B4BA 3WAWA 3VA7A 1ZVUA 4FM9A 4J3NA 3IGYB 1O25A 3BDGB 3NVLA 1Y7AA 4ZG9A 3UN2A 4KC6A 1DD5A 2GSNA 1Y1VA 4GTCA 1ISEA 4KATA 3GTGA 4CYSA 4ZG6A 3FKIA 3OEPA 1EW9A 3SZZA 5CHPA 4GTLA 4LR2A 3LXQA 4ILDA 2D1GA 4GTZA 2XCRB 2B63A 4FDIA 3N0CA 2VUMA 3UN5A 4LRAA 3CQZA 1HJKA 5AJ9A 4C2MC 1EW2A 2QZUA 4P5AA 4BLAA 1BJTA 3FOFA 2XRGA 4KAYA 3QX3A 1URBA 1I3QA 1ALJA 4FZBA 4LQYA 3M8YA 2R7ZA 4UPIA 5C66A 5GOVA 1O29A 4LRFA 1N2LA 3NUHA 3Q3QA 1O98A 3M7VA 4KM9A 1HDHA 1I50A 1F9NA 1KHLA 4KASA 2W5VA 1XXBA 1TWCA 1AJCA 1ALHA 2W5QA 3TG0A 1ED8A 1AB4A 1N2KA 1O28A 1WQFA 1BGWA 1E2SP 3OREA 3BUEA 4KAVA 4UPLA 3A52A 5DLTA 4UPHA 1ZEDA 2NVXA 1KQ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MK2 A;  3BDG B;  3NVL A;  1Y7A A;  4FDJ A;  4QAX A;  4CXK A;  4YR1 A;  1EW8 A;  5EGE A;  3UN2 A;  1KH9 A;  4ZG7 A;  1KHN A;  1SHN A;  4NWX A;  1EJJ A;  4ZG9 A;  5LIA A;  2GSN A;  1E1Z P;  3WAY A;  2GLQ A;  3T02 A;  4CYS A;  4ZG6 A;  5GRR A;  1EW9 A;  3NKN A;  2IFY A;  2VQR A;  2IUC A;  3SZZ A;  1ALK A;  4NWJ A;  1AUK A;  4KM4 A;  1E33 P;  4LR2 A;  3LXQ A;  5IJS A;  5TJ3 A;  3MK1 A;  5LRM A;  2D1G A;  1ANI A;  3NKR A;  4GTZ A;  2RH6 A;  4TN0 A;  3CMR A;  3WAV A;  1KH7 A;  2W8S A;  4CXU A;  5LQQ A;  1ANJ A;  3NKM A;  4FDI A;  3TX0 A;  3MK0 A;  2X98 A;  1AJB A;  3UN5 A;  1URA A;  4GTW A;  4LRA A;  1HJK A;  5AJ9 A;  1EW2 A;  3DYC A;  2W8D A;  5DLV A;  4CYR A;  3UNY A;  5L0B A;  4LR9 A;  1KH4 A;  2QZU A;  3IDD A;  3DPC A;  3T01 A;  1SHQ A;  5EGH A;  1EI6 A;  3SZY A;  4CXS A;  3BDG A;  1ELY A;  4LRE A;  3NKO A;  4GTY A;  1EQJ A;  2W5X A;  2W5S A;  4LRD A;  2XRG A;  5KXA A;  3E2D A;  4KAY A;  4LR8 A;  5HRT A;  1K7H A;  1URB A;  1AJA A;  3OT9 A;  1ALJ A;  1AJD A;  3BDH A;  1KH5 A;  4LRC A;  4LQY A;  3NKQ A;  4UOR A;  3M8Y A;  3WAX A;  3UN3 A;  4UPI A;  5C66 A;  5GOV A;  2ANH A;  4LR7 A;  4LRF A;  4N7T A;  3T00 A;  1E3C P;  1ZEF A;  1N2L A;  4KJD A;  2W5T A;  1FSU A;  3WBH A;  3BDF A;  4LRB A;  3Q3Q A;  3M8Z A;  1O98 A;  5L0E A;  4UOP A;  1ED9 A;  1ZEB A;  5K4P A;  5LRN A;  2W5R A;  3M7V A;  1HDH A;  2IUC B;  1ELZ A;  3TWZ A;  1KHL A;  5DLW A;  2GSO A;  1HQA A;  3B5Q A;  2W5V A;  1B8J A;  2W5W A;  2GA3 A;  1KHJ A;  4GTX A;  4KJG A;  1AJC A;  1ALH A;  1ELX A;  2W5Q A;  4ZGA A;  1ED8 A;  3UO0 A;  3TG0 A;  1N2K A;  3NKP A;  3ED4 A;  3IGZ B;  3KD8 A;  1Y6V A;  4MHX A;  1KHK A;  5INH A;  4MY4 A;  2XR9 A;  1E2S P;  5L0K A;  4MIV A;  5IJQ A;  4UOO A;  3M8W A;  2GSU A;  4KAV A;  4UPL A;  2G9Y A;  1ALI A;  3A52 A;  5DLT A;  3WAW A;  4UPK A;  4UPH A;  2ZKT A;  1ZED A;  1P49 A;  1O99 A;  3IGY B;  4B56 A; 
#chains in the Genus database with same CATH topology
 1VLO A;  3GEE A;  4BBR K;  3MK2 A;  4MEY A;  1O26 A;  4CXK A;  4A93 K;  5EGE A;  4ZG7 A;  1SHN A;  1EJJ A;  3GTJ C;  3PO3 K;  2R93 K;  1TWH K;  1E1Z P;  3M3Y K;  3WAY A;  2R93 A;  1TWH A;  3S14 C;  5GRR A;  4QJV A;  5IYD C;  5IOS A;  5IOQ A;  4Y7N C;  5IOT A;  3S15 K;  2XCO A;  3AD9 C;  2NVT C;  3RZD K;  5IJS A;  3GTO A;  4C3J C;  4TN0 A;  3CMR A;  2W8S A;  3NKM A;  2Y0S D;  2O5J A;  3G4A A;  3S2D C;  1J6X A;  1ZXO A;  4C3H C;  1TWF K;  1TWF A;  1URA A;  5JFE A;  4LOW A;  4GTW A;  4BLB A;  3DYC A;  2W8D A;  2NVX C;  1TWG K;  5C4J K;  3UNY A;  5L0B A;  4LR9 A;  4BY1 C;  4PAB A;  3HOV K;  2JA6 A;  2W7V A;  3V4G A;  3I4N K;  3DPC A;  4AYB L;  3GTP K;  3GTL C;  1SHQ A;  4CXS A;  3GTM C;  3GTP A;  1ELY A;  3NKO A;  3GTQ K;  4QIW D;  3H3V D;  3OPF A;  1EQJ A;  2W5X A;  1R9T C;  4YG2 A;  3N0B A;  3GTQ A;  2R92 C;  3G4C A;  1YCL A;  4LR8 A;  3S1Q K;  4A3E K;  3K7A C;  3NKQ A;  1IS1 A;  3WAX A;  1O24 A;  1WCM A;  1IE0 A;  3S0X A;  2P8T A;  3GTO C;  2PA8 L;  2ANH A;  4N7T A;  1PJ5 A;  5C4X C;  5CJ9 A;  4A3M K;  2W5T A;  1YX2 A;  3A8I A;  3BP8 C;  3GDZ A;  1F7U A;  4A3I C;  5L0E A;  1EK8 A;  4KB4 A;  3S16 C;  1ED9 A;  2E2H K;  4JK1 A;  2RGR A;  3AD7 C;  2JA7 A;  4QJV B;  2JA5 K;  1Y1V C;  1ELZ A;  3GTG C;  2JA5 A;  5IYC C;  2PPB A;  2GSO A;  2GA3 A;  1KHJ A;  4KJG A;  4WJ4 A;  2ZUF A;  2E2I K;  3UO0 A;  1IW7 A;  2ZUE A;  3NKP A;  1HI9 A;  3LPX A;  4A3L K;  3AQO A;  1Y6V A;  3HOW C;  1KHK A;  3H0G A;  4G7Z A;  3S2H C;  5FJ8 K;  2VUM C;  5IP7 C;  5L0K A;  4MIV A;  1SFO K;  5IJQ A;  4UOO A;  1EQR A;  2V6U A;  4XLN A;  2GSU A;  3CQZ C;  1SFO A;  1RU0 A;  1JVI A;  3S1M C;  1Y1W A;  1XZP A;  4BY7 C;  1BS2 A;  2A6H A;  1P49 A;  4BXX C;  1WOR A;  4P9S A;  4YR1 A;  4QAX A;  1L0W A;  1EW8 A;  2JA7 C;  3FOE A;  1KHN A;  4AH6 A;  5LIA A;  1VJE A;  3S17 K;  1WOP A;  4GTD A;  5M5W K;  1F7V A;  1VH2 A;  1O27 A;  3NKN A;  1I3Q C;  2IFY A;  4KB2 A;  2R7Z C;  4BKW A;  4MEX A;  4BBS C;  2WAQ D;  2NVY A;  2A68 A;  5TJ3 A;  5LRM A;  3GTK A;  4A3F K;  1EH1 A;  1I6H K;  5IYD K;  3WAV A;  1O2A A;  1KH7 A;  3N3Y A;  1K83 A;  4CXU A;  1DCH A;  1AJB A;  5JVO A;  5IP9 K;  4LK0 A;  3IPJ A;  4C3J K;  4Q5S A;  1I50 C;  1PJ7 A;  3S1N C;  4AYB D;  5D4D A;  4G7H A;  3S2D K;  4GTE A;  1WQH A;  4C3H K;  3DXJ A;  2ZFZ A;  4CYR A;  5IOR A;  3HOY C;  1TWC C;  3T01 A;  4WJ3 M;  5M3F K;  3SZY A;  4A3J K;  4A3G K;  4LRE A;  5L46 A;  2E2J K;  3ADA C;  3AH5 A;  2W5S A;  2CFA A;  4LRD A;  3E2D A;  2JA8 K;  4XSZ A;  1K7H A;  2PMZ L;  4KDD A;  1AJA A;  1AJD A;  1KH5 A;  3GTL K;  4LLG A;  3ERE D;  3UN3 A;  4C3I C;  3L4J A;  1R9T K;  1XZP B;  2GAH C;  4O2D A;  1E3C P;  4KM8 A;  1X31 C;  3HOZ C;  2NVQ C;  1WQG A;  4G0W A;  3I4M C;  3WBH A;  1BDF A;  3BDF A;  4LRB A;  1ZYR A;  4G0V A;  1HQM A;  1TWG A;  1WOS A;  5IYB K;  3LAJ A;  3HOX K;  3TFH A;  4UOP A;  4KMU A;  3HOU K;  5K4P A;  4GTB A;  5LRN A;  4C2M K;  3TWZ A;  3PO3 C;  2R93 C;  1TWH C;  3M3Y C;  1WSV A;  3PO2 K;  4GFQ A;  4X6A K;  4A3I K;  5DLW A;  2JH3 A;  3B5Q A;  1B8J A;  2W5W A;  3S15 C;  4GTF A;  4GTX A;  5C3E K;  1ELX A;  4YFK A;  1UV7 A;  1Y1V K;  3RZD C;  1TWA K;  3EQL A;  3FKI K;  5IYC K;  3RZO C;  3IGZ B;  1YNJ A;  1TWA A;  3AQP A;  3TFJ A;  1DCP A;  4LJZ A;  4OIR A;  1F93 A;  4KMD A;  1WIH A;  4MY4 A;  3M4O K;  5C44 C;  1GE9 A;  1TWF C;  1VGX A;  2PHC B;  4OIP A;  4A3C K;  3HKZ L;  1YNN A;  2B63 K;  2E2H A;  3HOW K;  4UPK A;  2ZKT A;  2P5M A;  1TWG C;  1O99 A;  2JA6 C;  4B56 A;  5M5X K;  4GT9 A;  3HOV C;  3CQZ K;  4FDJ A;  3I4N C;  2CFA B;  3GTP C;  1KH9 A;  4NWX A;  1JQW A;  3S1M K;  4A3B K;  4Q4Z A;  4WIL A;  4LK1 A;  3GTQ C;  2E2I A;  3T02 A;  1VRQ C;  1ZBS A;  2GLQ A;  4DDQ A;  4BXX K;  1J6W A;  2VQR A;  3S1Q C;  2IUC A;  4Y52 C;  1ALK A;  3TFI A;  4NWJ A;  1WCM C;  1AUK A;  4KM4 A;  1E33 P;  1B4A A;  3MK1 A;  1ANI A;  3NKR A;  2RH6 A;  1INN A;  2YU9 K;  5LQQ A;  1ANJ A;  1J6V A;  3TX0 A;  2YU9 A;  3MK0 A;  2X98 A;  4GTA A;  1EFW A;  5HL8 A;  4KAR A;  2E2H C;  2GAG C;  2JA5 C;  2XCQ A;  3CAG A;  5DLV A;  4XCH A;  1DCO A;  4KMH A;  1KH4 A;  3IDD A;  3GEH A;  2PMZ D;  1EI6 A;  5EGH A;  3GTJ K;  4P5B A;  3BDG A;  3LAP A;  4GTY A;  3GTJ A;  5FLM C;  3S14 K;  1XXC A;  5KXA A;  1TWC K;  4Y7N K;  2O5I A;  5HRT A;  4A3L C;  3H0G C;  4NOI A;  3WOD A;  3OT9 A;  4XSX A;  3BDH A;  1WOO A;  4LRC A;  4MQ9 A;  2KWA A;  2Y3P A;  3S1R C;  2NVT K;  4UOR A;  1V5V A;  4A3K C;  1SFO C;  4M1X A;  1IQ0 A;  3T00 A;  4LR7 A;  2V6S A;  3TTG A;  4YFX A;  1ZEF A;  3HXA A;  3JST A;  1Y1W C;  4OIN A;  4KJD A;  1FSU A;  4A3D C;  3AD8 C;  2V6T A;  2A69 A;  3M8Z A;  3MML B;  4KN4 A;  1ZEB A;  2W5R A;  1XXA A;  1PJ6 A;  1JOE A;  2NVQ K;  3L4K A;  2IUC B;  2NVX K;  3FHZ A;  3I4M K;  3S17 C;  4BY1 K;  4G0U A;  1HQA A;  2A6E A;  2PA8 D;  3GTM K;  4ZGA A;  3GTL A;  1O2B A;  2NVY C;  1USM A;  3GTK C;  5TMC A;  3GTM A;  1C0A A;  1O2F B;  3ED4 A;  2R92 K;  3KD8 A;  4A3F C;  4KMA A;  1K83 C;  1R9T A;  1I6H C;  1XZQ A;  3K7A K;  2R92 A;  4MHX A;  4KAW X;  3GSI A;  3HKZ D;  5INH A;  2WB1 L;  2XR9 A;  3GTO K;  4BBR C;  3RZO K;  3M8W A;  5IP9 C;  2G9Y A;  1ALI A;  1B4B A;  3WAW A;  5C4X K;  4A93 C;  3VA7 A;  1ZVU A;  4FM9 A;  2WAQ L;  5C44 K;  4J3N A;  1O25 A;  3IGY B;  3S16 K;  3BDG B;  3NVL A;  1Y7A A;  4GZY A;  4ZG9 A;  3UN2 A;  4KC6 A;  5TMF A;  4A3J C;  1DD5 A;  2GSN A;  3GTG K;  3A8J A;  4A3G C;  1Y1V A;  4GTC A;  1ISE A;  4KAT A;  2E2J C;  3GTG A;  2JA6 K;  3FKI A;  4CYS A;  4ZG6 A;  3OEP A;  2JA8 C;  1EW9 A;  1I6V A;  3SZZ A;  5CHP A;  4GTL A;  4LR2 A;  3LXQ A;  4ILD A;  4OIO A;  2D1G A;  1USO A;  4GTZ A;  4KN7 A;  4Y52 K;  1WSR A;  4ZH4 A;  2XCR B;  3S2H K;  2B63 A;  4FDI A;  1WCM K;  2VUM K;  5C4J C;  5IP7 K;  3N0C A;  2VUM A;  3UN5 A;  5IYB C;  3HOX C;  1IBA A;  4RMF A;  3HOU C;  4LRA A;  2Y0S L;  3CQZ A;  1SMY A;  1HJK A;  5AJ9 A;  4C2M C;  5E68 A;  4BY7 K;  1EW2 A;  4OIQ A;  3PO2 C;  4X6A C;  4C45 A;  2QZU A;  4P5A A;  4A3E C;  2D6F C;  2JA7 K;  1IL2 A;  4BLA A;  5C3E C;  1XZQ B;  1XPP A;  1TWA C;  1BJT A;  2CW0 A;  3FKI C;  3FOF A;  2XRG A;  5M3M K;  4KAY A;  1I3Q K;  3QX3 A;  1URB A;  1I3Q A;  1ALJ A;  4FZB A;  2R7Z K;  4A3M C;  4BBS K;  3BP3 A;  3GEI A;  4LQY A;  4QIW L;  3H3V L;  2R7Z A;  3M8Y A;  3M4O C;  4UPI A;  5C66 A;  5FLM K;  5GOV A;  1O29 A;  4LRF A;  4A3C C;  3H0G K;  4PAA A;  2BE5 A;  1N2L A;  2B63 C;  3S1R K;  3NUH A;  3Q3Q A;  2EBB A;  4A3K K;  1O98 A;  1I50 K;  3S1N K;  1Y1W K;  3M7V A;  4KM9 A;  2E2I C;  1HDH A;  1I50 A;  4A3B C;  1F9N A;  4A3D K;  1KHL A;  3HOY K;  4G7O A;  4KAS A;  2W5V A;  1XXB A;  1TWC A;  2FQT A;  1AJC A;  1ALH A;  2W5Q A;  3TG0 A;  1J98 A;  4YFN A;  1ED8 A;  1AB4 A;  3A8K A;  1N2K A;  1O28 A;  2WB1 D;  1WQF A;  2YU9 C;  1ZQ1 C;  2NVY K;  4C3I K;  3GTK K;  1BGW A;  4XLP A;  2FQO A;  1E2S P;  3ORE A;  3BUE A;  4KAV A;  4UPL A;  3A52 A;  5DLT A;  5M5Y K;  1K83 K;  3HOZ K;  4UPH A;  3GIR A;  1G51 A;  1ZED A;  2NVX A;  1KQ4 A; 
#chains in the Genus database with same CATH homology
 3MK2 A;  1O26 A;  4CXK A;  5EGE A;  4ZG7 A;  1SHN A;  1EJJ A;  1E1Z P;  3WAY A;  2R93 A;  1TWH A;  5GRR A;  5IOS A;  5IOQ A;  5IOT A;  2XCO A;  5IJS A;  3GTO A;  4C3J C;  4TN0 A;  3CMR A;  2W8S A;  3NKM A;  3G4A A;  4C3H C;  1ZXO A;  1TWF A;  1URA A;  5JFE A;  4GTW A;  4BLB A;  3DYC A;  2W8D A;  3UNY A;  5L0B A;  4LR9 A;  2JA6 A;  3V4G A;  3DPC A;  1SHQ A;  4CXS A;  3GTP A;  1ELY A;  3NKO A;  1EQJ A;  3OPF A;  2W5X A;  3GTQ A;  3N0B A;  4LR8 A;  3G4C A;  3NKQ A;  1IS1 A;  3WAX A;  1O24 A;  1WCM A;  3S0X A;  2ANH A;  4N7T A;  5CJ9 A;  2W5T A;  5L0E A;  1EK8 A;  4KB4 A;  1ED9 A;  2RGR A;  2JA7 A;  1ELZ A;  2JA5 A;  2GSO A;  2GA3 A;  1KHJ A;  4KJG A;  3UO0 A;  3NKP A;  3LPX A;  3AQO A;  1Y6V A;  1KHK A;  3H0G A;  5L0K A;  4MIV A;  5IJQ A;  4UOO A;  2GSU A;  1SFO A;  1Y1W A;  1P49 A;  4YR1 A;  4QAX A;  1EW8 A;  3FOE A;  1KHN A;  5LIA A;  4GTD A;  1O27 A;  3NKN A;  2IFY A;  4KB2 A;  4BKW A;  2NVY A;  5TJ3 A;  5LRM A;  3GTK A;  1EH1 A;  3WAV A;  1O2A A;  1KH7 A;  3N3Y A;  1K83 A;  4CXU A;  1AJB A;  5JVO A;  4GTE A;  1WQH A;  2ZFZ A;  4CYR A;  5IOR A;  3T01 A;  3SZY A;  4LRE A;  3AH5 A;  4LRD A;  2CFA A;  2W5S A;  3E2D A;  1K7H A;  4KDD A;  1AJA A;  1AJD A;  1KH5 A;  3ERE D;  3UN3 A;  4C3I C;  3L4J A;  1E3C P;  4KM8 A;  1WQG A;  4G0W A;  3WBH A;  3BDF A;  4LRB A;  4G0V A;  1TWG A;  3LAJ A;  4UOP A;  5K4P A;  4GTB A;  5LRN A;  3TWZ A;  4GFQ A;  5DLW A;  2JH3 A;  3B5Q A;  1B8J A;  2W5W A;  4GTF A;  4GTX A;  1ELX A;  3IGZ B;  1TWA A;  3AQP A;  4KMD A;  1WIH A;  4MY4 A;  1GE9 A;  2PHC B;  2E2H A;  4UPK A;  2ZKT A;  2P5M A;  1O99 A;  4B56 A;  4GT9 A;  4FDJ A;  2CFA B;  1KH9 A;  4NWX A;  2E2I A;  2GLQ A;  3T02 A;  1ZBS A;  4DDQ A;  2VQR A;  2IUC A;  1ALK A;  4NWJ A;  1AUK A;  4KM4 A;  1E33 P;  1B4A A;  3MK1 A;  1ANI A;  3NKR A;  2RH6 A;  5LQQ A;  1ANJ A;  3TX0 A;  2YU9 A;  3MK0 A;  2X98 A;  4GTA A;  4KAR A;  2XCQ A;  3CAG A;  5DLV A;  4KMH A;  1KH4 A;  3IDD A;  5EGH A;  1EI6 A;  4P5B A;  3BDG A;  3LAP A;  4GTY A;  3GTJ A;  5KXA A;  1XXC A;  5HRT A;  3OT9 A;  3BDH A;  4LRC A;  2KWA A;  2Y3P A;  4UOR A;  4M1X A;  3T00 A;  4LR7 A;  1ZEF A;  4KJD A;  1FSU A;  3M8Z A;  3MML B;  1ZEB A;  2W5R A;  1XXA A;  3L4K A;  2IUC B;  3FHZ A;  4G0U A;  1HQA A;  4ZGA A;  3GTL A;  1O2B A;  3GTM A;  3ED4 A;  3KD8 A;  4KMA A;  1R9T A;  2R92 A;  4MHX A;  4KAW X;  5INH A;  2XR9 A;  3M8W A;  2G9Y A;  1ALI A;  1B4B A;  3WAW A;  3VA7 A;  1ZVU A;  4FM9 A;  4J3N A;  3IGY B;  1O25 A;  3BDG B;  3NVL A;  1Y7A A;  4ZG9 A;  3UN2 A;  4KC6 A;  1DD5 A;  2GSN A;  1Y1V A;  4GTC A;  1ISE A;  4KAT A;  3GTG A;  4CYS A;  4ZG6 A;  3FKI A;  3OEP A;  1EW9 A;  3SZZ A;  5CHP A;  4GTL A;  4LR2 A;  3LXQ A;  4ILD A;  2D1G A;  4GTZ A;  2XCR B;  2B63 A;  4FDI A;  3N0C A;  2VUM A;  3UN5 A;  4LRA A;  3CQZ A;  1HJK A;  5AJ9 A;  4C2M C;  1EW2 A;  2QZU A;  4P5A A;  4BLA A;  1BJT A;  3FOF A;  2XRG A;  4KAY A;  3QX3 A;  1URB A;  1I3Q A;  1ALJ A;  4FZB A;  4LQY A;  3M8Y A;  2R7Z A;  4UPI A;  5C66 A;  5GOV A;  1O29 A;  4LRF A;  1N2L A;  3NUH A;  3Q3Q A;  1O98 A;  3M7V A;  4KM9 A;  1HDH A;  1I50 A;  1F9N A;  1KHL A;  4KAS A;  2W5V A;  1XXB A;  1TWC A;  1AJC A;  1ALH A;  2W5Q A;  3TG0 A;  1ED8 A;  1AB4 A;  1N2K A;  1O28 A;  1WQF A;  1BGW A;  1E2S P;  3ORE A;  3BUE A;  4KAV A;  4UPL A;  3A52 A;  5DLT A;  4UPH A;  1ZED A;  2NVX A;  1KQ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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