1AEIA

Crystal structure of the annexin xii hexamer
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
315
structure length
315
Chain Sequence
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQIKTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGLGTDENALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLLVSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSYPQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAERLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADDCSGDYKDLLLQITGH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the annexin XII hexamer and implications for bilayer insertion.
pubmed doi rcsb
molecule tags Calcium/phospholipid-binding
source organism Hydra vulgaris
molecule keywords ANNEXIN XII
total genus 127
structure length 315
sequence length 315
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 1995-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA03
1AXNA 1W3WA 1YCNA 4EVFA 1AEIA 1ANNA 1N00A 2IE6A 2HYWA 1SAVA 2HYUA 1G5NA 1AVHA 1HM6A 2IICA 1AOWA 3BRXA 1N44A 1HVDA 2ZHIA 1ANWA 2RANA 1A8AA 2XO2A 1MCXA 2H0MA 1ANXA 2H0KA 2Q4CA 1BO9A 1AIIA 1BC0A 1YJ0A 2HYVA 1BC1A 1HVGA 1YIIA 1BC3A 1HVEA 2H0LA 1BCYA 4HREA 4EVHA 1M9IA 1I4AA 1N42A 2XO3A 1BCZA 2ZOCA 4MDUA 1BCWA 1AVCA 2IE7A 1DM5A 1ALAA 1DK5A 1HVFA 2II2A 1HAKA 1A8BA 4MDVA 4X9PA 2ZHJA 1W7BA 1AVRA 1N41A 1XJLA 1W45A
chains in the Genus database with same CATH superfamily
1YCNA 3SOHB 1ANNA 1XT0B 3BRXA 2HYWA 1S9DE 1AOWA 3ABOA 2ZHIA 2RANA 1A8AA 2XO2A 1MCXA 3ABSA 2H0MA 3USWA 2HSNA 4JMIA 1KU1A 3AO0A 1YJ0A 2HYVA 1HVGA 4JXHA 1BC3A 4JMOA 4KMUX 4MDUA 4KN4X 1BCWA 4OIYA 1ALAA 1R8ME 4FQ0C 1AXNA 1AEIA 1N00A 2HYUA 1G5NA 1HM6A 2VXGA 1BC9A 1N44A 1HVDA 2R0DA 1BC0A 3HJLA 1LKVX 1QC7A 4FHRB 2H0LA 4EVHA 3L8NA 1R8QE 1Q8DA 1A8BA 4MDVA 3ANYA 1N41A 4HREA 1RE0B 4X9PA 1W45A 4A4PA 4EVFA 1SAVA 3USYA 2IICA 3LTLA 4Q2SA 1ANWA 1YGMA 2H0KA 1AIIA 1BC1A 1YIIA 2R09A 1C1KA 4Z21A 1HVEA 1BCYA 1M9IA 1I4AA 2ZOCA 4D7QA 2QEZA 1DM5A 1DK5A 4L5MA 1HVFA 2K6XA 3SWVA 2ZHJA 1R8SE 1W7BA 4C0AA 1XJLA 3ABRA 1W3WA 4C7PA 2IE6A 2OY9A 4JK1X 1AVHA 1UPTB 3TW5A 1ANXA 2Q4CA 1BO9A 4JWLA 3ABQA 4D7RA 4KN7X 1PBVA 1N42A 2XO3A 1BCZA 3AJCA 1AVCA 2IE7A 2II2A 1HAKA 1R4AE 1XSZA 1AVRA
chains in the Genus database with same CATH topology
1AXNA 1W3WA 1YCNA 4EVFA 1AEIA 1ANNA 1N00A 2IE6A 2HYWA 1SAVA 2HYUA 1G5NA 1AVHA 1HM6A 2IICA 1AOWA 3BRXA 1N44A 1HVDA 2ZHIA 1ANWA 2RANA 1A8AA 2XO2A 1MCXA 2H0MA 1ANXA 2H0KA 2Q4CA 1BO9A 1AIIA 1BC0A 1YJ0A 2HYVA 1BC1A 1HVGA 1YIIA 1BC3A 1HVEA 2H0LA 1BCYA 4HREA 4EVHA 1M9IA 1I4AA 1N42A 2XO3A 1BCZA 2ZOCA 4MDUA 1BCWA 1AVCA 2IE7A 1DM5A 1ALAA 1DK5A 1HVFA 2II2A 1HAKA 1A8BA 4MDVA 4X9PA 2ZHJA 1W7BA 1AVRA 1N41A 1XJLA 1W45A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AXN A;  1W3W A;  1YCN A;  4EVF A;  1AEI A;  1ANN A;  1N00 A;  2IE6 A;  2HYW A;  1SAV A;  2HYU A;  1G5N A;  1AVH A;  1HM6 A;  2IIC A;  1AOW A;  3BRX A;  1N44 A;  1HVD A;  2ZHI A;  1ANW A;  2RAN A;  1A8A A;  2XO2 A;  1MCX A;  2H0M A;  1ANX A;  2H0K A;  2Q4C A;  1BO9 A;  1AII A;  1BC0 A;  1YJ0 A;  2HYV A;  1BC1 A;  1HVG A;  1YII A;  1BC3 A;  1HVE A;  2H0L A;  1BCY A;  4HRE A;  4EVH A;  1M9I A;  1I4A A;  1N42 A;  2XO3 A;  1BCZ A;  2ZOC A;  4MDU A;  1BCW A;  1AVC A;  2IE7 A;  1DM5 A;  1ALA A;  1DK5 A;  1HVF A;  2II2 A;  1HAK A;  1A8B A;  4MDV A;  4X9P A;  2ZHJ A;  1W7B A;  1AVR A;  1N41 A;  1XJL A;  1W45 A; 
#chains in the Genus database with same CATH topology
 1YCN A;  3SOH B;  1ANN A;  1XT0 B;  3BRX A;  2HYW A;  1S9D E;  1AOW A;  3ABO A;  2ZHI A;  2RAN A;  1A8A A;  2XO2 A;  1MCX A;  3ABS A;  2H0M A;  3USW A;  2HSN A;  4JMI A;  1KU1 A;  3AO0 A;  1YJ0 A;  2HYV A;  1HVG A;  4JXH A;  1BC3 A;  4JMO A;  4KMU X;  4MDU A;  4KN4 X;  1BCW A;  4OIY A;  1ALA A;  1R8M E;  4FQ0 C;  1AXN A;  1AEI A;  1N00 A;  2HYU A;  1G5N A;  1HM6 A;  2VXG A;  1BC9 A;  1N44 A;  1HVD A;  2R0D A;  1BC0 A;  3HJL A;  1LKV X;  1QC7 A;  4FHR B;  2H0L A;  4EVH A;  3L8N A;  1R8Q E;  1Q8D A;  1A8B A;  4MDV A;  3ANY A;  1N41 A;  4HRE A;  1RE0 B;  4X9P A;  1W45 A;  4A4P A;  4EVF A;  1SAV A;  3USY A;  2IIC A;  3LTL A;  4Q2S A;  1ANW A;  1YGM A;  2H0K A;  1AII A;  1BC1 A;  1YII A;  2R09 A;  1C1K A;  4Z21 A;  1HVE A;  1BCY A;  1M9I A;  1I4A A;  2ZOC A;  4D7Q A;  2QEZ A;  1DM5 A;  1DK5 A;  4L5M A;  1HVF A;  2K6X A;  3SWV A;  2ZHJ A;  1R8S E;  1W7B A;  4C0A A;  1XJL A;  3ABR A;  1W3W A;  4C7P A;  2IE6 A;  2OY9 A;  4JK1 X;  1AVH A;  1UPT B;  3TW5 A;  1ANX A;  2Q4C A;  1BO9 A;  4JWL A;  3ABQ A;  4D7R A;  4KN7 X;  1PBV A;  1N42 A;  2XO3 A;  1BCZ A;  3AJC A;  1AVC A;  2IE7 A;  2II2 A;  1HAK A;  1R4A E;  1XSZ A;  1AVR A; 
#chains in the Genus database with same CATH homology
 1AXN A;  1W3W A;  1YCN A;  4EVF A;  1AEI A;  1ANN A;  1N00 A;  2IE6 A;  2HYW A;  1SAV A;  2HYU A;  1G5N A;  1AVH A;  1HM6 A;  2IIC A;  1AOW A;  3BRX A;  1N44 A;  1HVD A;  2ZHI A;  1ANW A;  2RAN A;  1A8A A;  2XO2 A;  1MCX A;  2H0M A;  1ANX A;  2H0K A;  2Q4C A;  1BO9 A;  1AII A;  1BC0 A;  1YJ0 A;  2HYV A;  1BC1 A;  1HVG A;  1YII A;  1BC3 A;  1HVE A;  2H0L A;  1BCY A;  4HRE A;  4EVH A;  1M9I A;  1I4A A;  1N42 A;  2XO3 A;  1BCZ A;  2ZOC A;  4MDU A;  1BCW A;  1AVC A;  2IE7 A;  1DM5 A;  1ALA A;  1DK5 A;  1HVF A;  2II2 A;  1HAK A;  1A8B A;  4MDV A;  4X9P A;  2ZHJ A;  1W7B A;  1AVR A;  1N41 A;  1XJL A;  1W45 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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