1AEIA

Crystal structure of the annexin xii hexamer
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
315
structure length
315
Chain Sequence
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQIKTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGLGTDENALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLLVSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSYPQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAERLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADDCSGDYKDLLLQITGH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the annexin XII hexamer and implications for bilayer insertion.
pubmed doi rcsb
molecule tags Calcium/phospholipid-binding
source organism Hydra vulgaris
molecule keywords ANNEXIN XII
total genus 127
structure length 315
sequence length 315
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 1995-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1aeiA03
1AEIA 1ANXA 1AVCA 1M9IA 1BO9A 1AXNA 1HVEA 2HYUA 1BC1A 2Q4CA 2ZOCA 4EVFA 2H0LA 1MCXA 4HREA 1AIIA 1BCWA 1N44A 3BRXA 1ANWA 1YCNA 1YIIA 1DM5A 1AVHA 2XO2A 1BCZA 1SAVA 1A8AA 1W45A 1AVRA 2H0MA 1I4AA 1BCYA 1ALAA 1XJLA 2XO3A 2RANA 1BC3A 1HVGA 1N42A 2II2A 2ZHIA 2H0KA 4MDUA 1N41A 2IE6A 4X9PA 1HAKA 1YJ0A 2HYVA 1W7BA 4EVHA 1A8BA 1HVDA 2IICA 2ZHJA 2HYWA 1ANNA 1G5NA 4MDVA 1HM6A 1HVFA 1BC0A 1W3WA 1AOWA 1N00A 1DK5A 2IE7A
chains in the Genus database with same CATH superfamily
1ANXA 4JMIA 2HSNA 2Q4CA 1LKVX 3ABRA 3BRXA 1YIIA 1BCZA 1W45A 1BCYA 2OY9A 2II2A 3SWVA 2IE6A 4EVHA 3LTLA 3SOHB 1A8BA 2HYWA 1ANNA 3USWA 4A4PA 2R09A 3ABSA 1C1KA 1M9IA 1BO9A 1HVEA 4C0AA 1BC1A 2H0LA 1PBVA 1R8ME 4D7RA 1BCWA 1YCNA 4FHRB 1SAVA 2K6XA 1XJLA 2XO3A 1BC3A 1HVGA 4L5MA 1HAKA 1YJ0A 1W7BA 1HVDA 4OIYA 1YGMA 2ZHJA 3ABQA 1Q8DA 3USYA 1HVFA 1BC0A 1XT0B 1QC7A 1DK5A 1RE0B 4Z21A 1AEIA 1AVCA 3AJCA 3L8NA 2ZOCA 4JWLA 4EVFA 4HREA 1AIIA 1ANWA 3AO0A 1AVHA 2H0MA 1I4AA 2QEZA 3ABOA 2RANA 1N42A 2ZHIA 4JMOA 2H0KA 3ANYA 4X9PA 3TW5A 2IICA 4KMUX 1G5NA 4C7PA 1W3WA 1R8SE 1KU1A 4FQ0C 1AXNA 2HYUA 4JXHA 4KN7X 1MCXA 1R8QE 1S9DE 1N44A 1DM5A 2XO2A 4KN4X 1UPTB 1A8AA 1AVRA 1R4AE 2R0DA 1ALAA 2VXGA 1XSZA 4MDUA 1N41A 2HYVA 4D7QA 3HJLA 4MDVA 1BC9A 1HM6A 4Q2SA 1AOWA 1N00A 4JK1X 2IE7A
chains in the Genus database with same CATH topology
1AEIA 1ANXA 1AVCA 1M9IA 1BO9A 1AXNA 1HVEA 2HYUA 1BC1A 2Q4CA 2ZOCA 4EVFA 2H0LA 1MCXA 4HREA 1AIIA 1BCWA 1N44A 3BRXA 1ANWA 1YCNA 1YIIA 1DM5A 1AVHA 2XO2A 1BCZA 1SAVA 1A8AA 1W45A 1AVRA 2H0MA 1I4AA 1BCYA 1ALAA 1XJLA 2XO3A 2RANA 1BC3A 1HVGA 1N42A 2II2A 2ZHIA 2H0KA 4MDUA 1N41A 2IE6A 4X9PA 1HAKA 1YJ0A 2HYVA 1W7BA 4EVHA 1A8BA 1HVDA 2IICA 2ZHJA 2HYWA 1ANNA 1G5NA 4MDVA 1HM6A 1HVFA 1BC0A 1W3WA 1AOWA 1N00A 1DK5A 2IE7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AEI A;  1ANX A;  1AVC A;  1M9I A;  1BO9 A;  1AXN A;  1HVE A;  2HYU A;  1BC1 A;  2Q4C A;  2ZOC A;  4EVF A;  2H0L A;  1MCX A;  4HRE A;  1AII A;  1BCW A;  1N44 A;  3BRX A;  1ANW A;  1YCN A;  1YII A;  1DM5 A;  1AVH A;  2XO2 A;  1BCZ A;  1SAV A;  1A8A A;  1W45 A;  1AVR A;  2H0M A;  1I4A A;  1BCY A;  1ALA A;  1XJL A;  2XO3 A;  2RAN A;  1BC3 A;  1HVG A;  1N42 A;  2II2 A;  2ZHI A;  2H0K A;  4MDU A;  1N41 A;  2IE6 A;  4X9P A;  1HAK A;  1YJ0 A;  2HYV A;  1W7B A;  4EVH A;  1A8B A;  1HVD A;  2IIC A;  2ZHJ A;  2HYW A;  1ANN A;  1G5N A;  4MDV A;  1HM6 A;  1HVF A;  1BC0 A;  1W3W A;  1AOW A;  1N00 A;  1DK5 A;  2IE7 A; 
#chains in the Genus database with same CATH topology
 1ANX A;  4JMI A;  2HSN A;  2Q4C A;  1LKV X;  3ABR A;  3BRX A;  1YII A;  1BCZ A;  1W45 A;  1BCY A;  2OY9 A;  2II2 A;  3SWV A;  2IE6 A;  4EVH A;  3LTL A;  3SOH B;  1A8B A;  2HYW A;  1ANN A;  3USW A;  4A4P A;  2R09 A;  3ABS A;  1C1K A;  1M9I A;  1BO9 A;  1HVE A;  4C0A A;  1BC1 A;  2H0L A;  1PBV A;  1R8M E;  4D7R A;  1BCW A;  1YCN A;  4FHR B;  1SAV A;  2K6X A;  1XJL A;  2XO3 A;  1BC3 A;  1HVG A;  4L5M A;  1HAK A;  1YJ0 A;  1W7B A;  1HVD A;  4OIY A;  1YGM A;  2ZHJ A;  3ABQ A;  1Q8D A;  3USY A;  1HVF A;  1BC0 A;  1XT0 B;  1QC7 A;  1DK5 A;  1RE0 B;  4Z21 A;  1AEI A;  1AVC A;  3AJC A;  3L8N A;  2ZOC A;  4JWL A;  4EVF A;  4HRE A;  1AII A;  1ANW A;  3AO0 A;  1AVH A;  2H0M A;  1I4A A;  2QEZ A;  3ABO A;  2RAN A;  1N42 A;  2ZHI A;  4JMO A;  2H0K A;  3ANY A;  4X9P A;  3TW5 A;  2IIC A;  4KMU X;  1G5N A;  4C7P A;  1W3W A;  1R8S E;  1KU1 A;  4FQ0 C;  1AXN A;  2HYU A;  4JXH A;  4KN7 X;  1MCX A;  1R8Q E;  1S9D E;  1N44 A;  1DM5 A;  2XO2 A;  4KN4 X;  1UPT B;  1A8A A;  1AVR A;  1R4A E;  2R0D A;  1ALA A;  2VXG A;  1XSZ A;  4MDU A;  1N41 A;  2HYV A;  4D7Q A;  3HJL A;  4MDV A;  1BC9 A;  1HM6 A;  4Q2S A;  1AOW A;  1N00 A;  4JK1 X;  2IE7 A; 
#chains in the Genus database with same CATH homology
 1AEI A;  1ANX A;  1AVC A;  1M9I A;  1BO9 A;  1AXN A;  1HVE A;  2HYU A;  1BC1 A;  2Q4C A;  2ZOC A;  4EVF A;  2H0L A;  1MCX A;  4HRE A;  1AII A;  1BCW A;  1N44 A;  3BRX A;  1ANW A;  1YCN A;  1YII A;  1DM5 A;  1AVH A;  2XO2 A;  1BCZ A;  1SAV A;  1A8A A;  1W45 A;  1AVR A;  2H0M A;  1I4A A;  1BCY A;  1ALA A;  1XJL A;  2XO3 A;  2RAN A;  1BC3 A;  1HVG A;  1N42 A;  2II2 A;  2ZHI A;  2H0K A;  4MDU A;  1N41 A;  2IE6 A;  4X9P A;  1HAK A;  1YJ0 A;  2HYV A;  1W7B A;  4EVH A;  1A8B A;  1HVD A;  2IIC A;  2ZHJ A;  2HYW A;  1ANN A;  1G5N A;  4MDV A;  1HM6 A;  1HVF A;  1BC0 A;  1W3W A;  1AOW A;  1N00 A;  1DK5 A;  2IE7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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