1ANW | Genus

Total Genus 124

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	124
sequence length	319
structure length	319
Chain Sequence	AQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 319 atoms

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319 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Calcium/phospholipid-binding protein
source organism	Homo sapiens
publication title	The effect of metal binding on the structure of annexin V and implications for membrane binding. pubmed doi rcsb
molecule keywords	ANNEXIN V
total genus	124
structure length	319
sequence length	319
chains with identical sequence	B
ec nomenclature
pdb deposition date	1993-10-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00191	Annexin	Annexin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1anwA02
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1anwA04
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1anwA01
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1anwA03

2HYUA 4MDVA 1ANNA 2ZHIA 1HVGA 2IE6A 4X9PA 1M9IA 1DK5A 1AIIA 2H0MA 1BCWA 2IICA 1AVRA 4HREA 1YIIA 1HVDA 4MDUA 1BC3A 1ALAA 1A8BA 1HAKA 1G5NA 1AOWA 1HVEA 1HM6A 1YCNA 1ANWA 1W3WA 1BCZA 1BCYA 1DM5A 2HYVA 1XJLA 1AVHA 2Q4CA 1A8AA 2RANA 1YJ0A 2II2A 2ZOCA 1W45A 2XO2A 2ZHJA 1I4AA 2XO3A 2IE7A 1ANXA 1AEIA 1HVFA 1AXNA 1MCXA 1N42A 4EVFA 1BC0A 2H0LA 1N00A 4EVHA 2HYWA 1BC1A 1SAVA 2H0KA 1N41A 1BO9A 3BRXA 1N44A 1W7BA 1AVCA
chains in the Genus database with same CATH superfamily

4KMUX 2ZHIA 3ANYA 1HVGA 4X9PA 1AIIA 1S9DE 1R4AE 1BCWA 2IICA 1AVRA 1R8SE 4HREA 3SWVA 4FHRB 1HVEA 1KU1A 1HM6A 1BCZA 3LTLA 1YJ0A 1I4AA 2XO3A 1N42A 3USYA 1AXNA 1MCXA 1QC7A 2H0LA 1YGMA 1SAVA 1C1KA 3BRXA 1BC3A 3ABSA 2R0DA 4C7PA 3SOHB 2IE6A 4FQ0C 2H0MA 4MDUA 1A8BA 4JK1X 1W3WA 1DM5A 2K6XA 2QEZA 1XJLA 1AVHA 3ABQA 2ZHJA 2IE7A 1ANXA 1AEIA 4A4PA 4EVHA 2HYWA 2H0KA 1N41A 1PBVA 1BC9A 2HYUA 4MDVA 2R09A 1Q8DA 1M9IA 4D7QA 1DK5A 2HSNA 4C0AA 1RE0B 1HAKA 1G5NA 1AOWA 1XSZA 1YCNA 1ANWA 1BCYA 2HYVA 1UPTB 4Q2SA 3TW5A 1A8AA 4JWLA 3AO0A 3L8NA 1HVFA 4EVFA 1N00A 1BC1A 1N44A 4JMOA 1ANNA 4L5MA 1R8QE 1R8ME 3HJLA 1YIIA 1ALAA 1XT0B 4KN7X 1LKVX 4Z21A 3ABOA 2VXGA 4JXHA 1AVCA 3AJCA 4JMIA 2Q4CA 2RANA 2II2A 2ZOCA 1W45A 2XO2A 4D7RA 2OY9A 1BC0A 3USWA 3ABRA 4OIYA 4KN4X 1BO9A 1W7BA 1HVDA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2HYU A;  4MDV A;  1ANN A;  2ZHI A;  1HVG A;  2IE6 A;  4X9P A;  1M9I A;  1DK5 A;  1AII A;  2H0M A;  1BCW A;  2IIC A;  1AVR A;  4HRE A;  1YII A;  1HVD A;  4MDU A;  1BC3 A;  1ALA A;  1A8B A;  1HAK A;  1G5N A;  1AOW A;  1HVE A;  1HM6 A;  1YCN A;  1ANW A;  1W3W A;  1BCZ A;  1BCY A;  1DM5 A;  2HYV A;  1XJL A;  1AVH A;  2Q4C A;  1A8A A;  2RAN A;  1YJ0 A;  2II2 A;  2ZOC A;  1W45 A;  2XO2 A;  2ZHJ A;  1I4A A;  2XO3 A;  2IE7 A;  1ANX A;  1AEI A;  1HVF A;  1AXN A;  1MCX A;  1N42 A;  4EVF A;  1BC0 A;  2H0L A;  1N00 A;  4EVH A;  2HYW A;  1BC1 A;  1SAV A;  2H0K A;  1N41 A;  1BO9 A;  3BRX A;  1N44 A;  1W7B A;  1AVC A; 
#chains in the Genus database with same CATH topology
 4KMU X;  2ZHI A;  3ANY A;  1HVG A;  4X9P A;  1AII A;  1S9D E;  1R4A E;  1BCW A;  2IIC A;  1AVR A;  1R8S E;  4HRE A;  3SWV A;  4FHR B;  1HVE A;  1KU1 A;  1HM6 A;  1BCZ A;  3LTL A;  1YJ0 A;  1I4A A;  2XO3 A;  1N42 A;  3USY A;  1AXN A;  1MCX A;  1QC7 A;  2H0L A;  1YGM A;  1SAV A;  1C1K A;  3BRX A;  1BC3 A;  3ABS A;  2R0D A;  4C7P A;  3SOH B;  2IE6 A;  4FQ0 C;  2H0M A;  4MDU A;  1A8B A;  4JK1 X;  1W3W A;  1DM5 A;  2K6X A;  2QEZ A;  1XJL A;  1AVH A;  3ABQ A;  2ZHJ A;  2IE7 A;  1ANX A;  1AEI A;  4A4P A;  4EVH A;  2HYW A;  2H0K A;  1N41 A;  1PBV A;  1BC9 A;  2HYU A;  4MDV A;  2R09 A;  1Q8D A;  1M9I A;  4D7Q A;  1DK5 A;  2HSN A;  4C0A A;  1RE0 B;  1HAK A;  1G5N A;  1AOW A;  1XSZ A;  1YCN A;  1ANW A;  1BCY A;  2HYV A;  1UPT B;  4Q2S A;  3TW5 A;  1A8A A;  4JWL A;  3AO0 A;  3L8N A;  1HVF A;  4EVF A;  1N00 A;  1BC1 A;  1N44 A;  4JMO A;  1ANN A;  4L5M A;  1R8Q E;  1R8M E;  3HJL A;  1YII A;  1ALA A;  1XT0 B;  4KN7 X;  1LKV X;  4Z21 A;  3ABO A;  2VXG A;  4JXH A;  1AVC A;  3AJC A;  4JMI A;  2Q4C A;  2RAN A;  2II2 A;  2ZOC A;  1W45 A;  2XO2 A;  4D7R A;  2OY9 A;  1BC0 A;  3USW A;  3ABR A;  4OIY A;  4KN4 X;  1BO9 A;  1W7B A;  1HVD A; 
#chains in the Genus database with same CATH homology
 2HYU A;  4MDV A;  1ANN A;  2ZHI A;  1HVG A;  2IE6 A;  4X9P A;  1M9I A;  1DK5 A;  1AII A;  2H0M A;  1BCW A;  2IIC A;  1AVR A;  4HRE A;  1YII A;  1HVD A;  4MDU A;  1BC3 A;  1ALA A;  1A8B A;  1HAK A;  1G5N A;  1AOW A;  1HVE A;  1HM6 A;  1YCN A;  1ANW A;  1W3W A;  1BCZ A;  1BCY A;  1DM5 A;  2HYV A;  1XJL A;  1AVH A;  2Q4C A;  1A8A A;  2RAN A;  1YJ0 A;  2II2 A;  2ZOC A;  1W45 A;  2XO2 A;  2ZHJ A;  1I4A A;  2XO3 A;  2IE7 A;  1ANX A;  1AEI A;  1HVF A;  1AXN A;  1MCX A;  1N42 A;  4EVF A;  1BC0 A;  2H0L A;  1N00 A;  4EVH A;  2HYW A;  1BC1 A;  1SAV A;  2H0K A;  1N41 A;  1BO9 A;  3BRX A;  1N44 A;  1W7B A;  1AVC A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1ANWA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations