1ANXA

The crystal structure of a new high-calcium form of annexin v
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
316
structure length
316
Chain Sequence
QVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of a new high-calcium form of annexin V.
pubmed doi rcsb
molecule tags Calcium/phospholipid-binding protein
source organism Homo sapiens
molecule keywords ANNEXIN V
total genus 128
structure length 316
sequence length 316
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1993-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA03
1DK5A 1YJ0A 1DM5A 1ANWA 1A8BA 4MDVA 1ANXA 1BCZA 1YIIA 1N42A 1N41A 2Q4CA 4MDUA 4X9PA 1AVHA 1BO9A 1HM6A 1XJLA 1YCNA 4EVHA 4HREA 1G5NA 1MCXA 2XO2A 2XO3A 1W7BA 1BC1A 1AXNA 4EVFA 1AVRA 1BC0A 2HYUA 1HVEA 1W45A 1HVDA 2H0KA 1AVCA 2RANA 2ZOCA 1I4AA 1HAKA 2IE7A 2II2A 1SAVA 2H0MA 1AIIA 2IE6A 2IICA 1ANNA 1HVGA 1N44A 2H0LA 1N00A 2ZHJA 3BRXA 1BCYA 1BC3A 1ALAA 1M9IA 2HYWA 1AEIA 1W3WA 1A8AA 2HYVA 1AOWA 2ZHIA 1HVFA 1BCWA
chains in the Genus database with same CATH superfamily
1DM5A 4MDVA 1XT0B 1PBVA 1BCZA 1N41A 2Q4CA 4JMIA 1RE0B 3SOHB 1XJLA 4L5MA 3HJLA 4JMOA 3L8NA 3ABSA 3USWA 3SWVA 1AVCA 1C1KA 2H0MA 1AIIA 3AO0A 1N44A 1M9IA 2XO3A 4Q2SA 4D7RA 4KN7X 1ANWA 1LKVX 1R8QE 1ANXA 4X9PA 3AJCA 1HM6A 2R09A 1R8ME 4EVHA 4FQ0C 4Z21A 2XO2A 4EVFA 1AVRA 1S9DE 1UPTB 4C7PA 2ZOCA 2II2A 1HAKA 2R0DA 4D7QA 2IICA 1ANNA 2H0LA 1BCYA 1BC3A 1ALAA 3USYA 2HYVA 1YIIA 1AOWA 1YJ0A 1A8BA 2QEZA 4JXHA 1R8SE 1N42A 4MDUA 1XSZA 2HSNA 4FHRB 4JK1X 1BO9A 4JWLA 1MCXA 1W7BA 1BC1A 3ABOA 1AXNA 1BC9A 1W45A 1HVDA 2H0KA 3ANYA 4C0AA 2IE7A 2IE6A 2K6XA 1HVGA 2ZHJA 3BRXA 1W3WA 1HVEA 1DK5A 1KU1A 1YGMA 4KMUX 1AVHA 1QC7A 1YCNA 4KN4X 4HREA 1G5NA 4OIYA 3ABQA 3TW5A 2VXGA 1BC0A 4A4PA 2OY9A 2HYUA 3ABRA 2RANA 1SAVA 3LTLA 1N00A 1Q8DA 2HYWA 1AEIA 1R4AE 1A8AA 2ZHIA 1I4AA 1HVFA 1BCWA
chains in the Genus database with same CATH topology
1DK5A 1YJ0A 1DM5A 1ANWA 1A8BA 4MDVA 1ANXA 1BCZA 1YIIA 1N42A 1N41A 2Q4CA 4MDUA 4X9PA 1AVHA 1BO9A 1HM6A 1XJLA 1YCNA 4EVHA 4HREA 1G5NA 1MCXA 2XO2A 2XO3A 1W7BA 1BC1A 1AXNA 4EVFA 1AVRA 1BC0A 2HYUA 1HVEA 1W45A 1HVDA 2H0KA 1AVCA 2RANA 2ZOCA 1I4AA 1HAKA 2IE7A 2II2A 1SAVA 2H0MA 1AIIA 2IE6A 2IICA 1ANNA 1HVGA 1N44A 2H0LA 1N00A 2ZHJA 3BRXA 1BCYA 1BC3A 1ALAA 1M9IA 2HYWA 1AEIA 1W3WA 1A8AA 2HYVA 1AOWA 2ZHIA 1HVFA 1BCWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DK5 A;  1YJ0 A;  1DM5 A;  1ANW A;  1A8B A;  4MDV A;  1ANX A;  1BCZ A;  1YII A;  1N42 A;  1N41 A;  2Q4C A;  4MDU A;  4X9P A;  1AVH A;  1BO9 A;  1HM6 A;  1XJL A;  1YCN A;  4EVH A;  4HRE A;  1G5N A;  1MCX A;  2XO2 A;  2XO3 A;  1W7B A;  1BC1 A;  1AXN A;  4EVF A;  1AVR A;  1BC0 A;  2HYU A;  1HVE A;  1W45 A;  1HVD A;  2H0K A;  1AVC A;  2RAN A;  2ZOC A;  1I4A A;  1HAK A;  2IE7 A;  2II2 A;  1SAV A;  2H0M A;  1AII A;  2IE6 A;  2IIC A;  1ANN A;  1HVG A;  1N44 A;  2H0L A;  1N00 A;  2ZHJ A;  3BRX A;  1BCY A;  1BC3 A;  1ALA A;  1M9I A;  2HYW A;  1AEI A;  1W3W A;  1A8A A;  2HYV A;  1AOW A;  2ZHI A;  1HVF A;  1BCW A; 
#chains in the Genus database with same CATH topology
 1DM5 A;  4MDV A;  1XT0 B;  1PBV A;  1BCZ A;  1N41 A;  2Q4C A;  4JMI A;  1RE0 B;  3SOH B;  1XJL A;  4L5M A;  3HJL A;  4JMO A;  3L8N A;  3ABS A;  3USW A;  3SWV A;  1AVC A;  1C1K A;  2H0M A;  1AII A;  3AO0 A;  1N44 A;  1M9I A;  2XO3 A;  4Q2S A;  4D7R A;  4KN7 X;  1ANW A;  1LKV X;  1R8Q E;  1ANX A;  4X9P A;  3AJC A;  1HM6 A;  2R09 A;  1R8M E;  4EVH A;  4FQ0 C;  4Z21 A;  2XO2 A;  4EVF A;  1AVR A;  1S9D E;  1UPT B;  4C7P A;  2ZOC A;  2II2 A;  1HAK A;  2R0D A;  4D7Q A;  2IIC A;  1ANN A;  2H0L A;  1BCY A;  1BC3 A;  1ALA A;  3USY A;  2HYV A;  1YII A;  1AOW A;  1YJ0 A;  1A8B A;  2QEZ A;  4JXH A;  1R8S E;  1N42 A;  4MDU A;  1XSZ A;  2HSN A;  4FHR B;  4JK1 X;  1BO9 A;  4JWL A;  1MCX A;  1W7B A;  1BC1 A;  3ABO A;  1AXN A;  1BC9 A;  1W45 A;  1HVD A;  2H0K A;  3ANY A;  4C0A A;  2IE7 A;  2IE6 A;  2K6X A;  1HVG A;  2ZHJ A;  3BRX A;  1W3W A;  1HVE A;  1DK5 A;  1KU1 A;  1YGM A;  4KMU X;  1AVH A;  1QC7 A;  1YCN A;  4KN4 X;  4HRE A;  1G5N A;  4OIY A;  3ABQ A;  3TW5 A;  2VXG A;  1BC0 A;  4A4P A;  2OY9 A;  2HYU A;  3ABR A;  2RAN A;  1SAV A;  3LTL A;  1N00 A;  1Q8D A;  2HYW A;  1AEI A;  1R4A E;  1A8A A;  2ZHI A;  1I4A A;  1HVF A;  1BCW A; 
#chains in the Genus database with same CATH homology
 1DK5 A;  1YJ0 A;  1DM5 A;  1ANW A;  1A8B A;  4MDV A;  1ANX A;  1BCZ A;  1YII A;  1N42 A;  1N41 A;  2Q4C A;  4MDU A;  4X9P A;  1AVH A;  1BO9 A;  1HM6 A;  1XJL A;  1YCN A;  4EVH A;  4HRE A;  1G5N A;  1MCX A;  2XO2 A;  2XO3 A;  1W7B A;  1BC1 A;  1AXN A;  4EVF A;  1AVR A;  1BC0 A;  2HYU A;  1HVE A;  1W45 A;  1HVD A;  2H0K A;  1AVC A;  2RAN A;  2ZOC A;  1I4A A;  1HAK A;  2IE7 A;  2II2 A;  1SAV A;  2H0M A;  1AII A;  2IE6 A;  2IIC A;  1ANN A;  1HVG A;  1N44 A;  2H0L A;  1N00 A;  2ZHJ A;  3BRX A;  1BCY A;  1BC3 A;  1ALA A;  1M9I A;  2HYW A;  1AEI A;  1W3W A;  1A8A A;  2HYV A;  1AOW A;  2ZHI A;  1HVF A;  1BCW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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