1ANXA

The crystal structure of a new high-calcium form of annexin v
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
316
structure length
316
Chain Sequence
QVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of a new high-calcium form of annexin V.
pubmed doi rcsb
molecule tags Calcium/phospholipid-binding protein
source organism Homo sapiens
molecule keywords ANNEXIN V
total genus 128
structure length 316
sequence length 316
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1993-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1anxA03
1SAVA 1N00A 2II2A 1AXNA 1I4AA 4MDUA 1XJLA 1YCNA 1HVDA 2ZHIA 1BO9A 1ANXA 2HYUA 1YIIA 2ZOCA 1BC0A 1MCXA 1YJ0A 1M9IA 2Q4CA 1AEIA 1BC1A 1HM6A 3BRXA 1A8BA 1AVHA 4X9PA 2IE6A 1G5NA 4HREA 1ANWA 2HYWA 1BCWA 1DK5A 1W3WA 1W7BA 2RANA 1HVEA 2XO3A 1N44A 2IE7A 4EVHA 1AVRA 2H0KA 1BC3A 1ALAA 1A8AA 1HAKA 1N41A 1N42A 1AIIA 2ZHJA 1DM5A 1HVGA 2IICA 1AVCA 1W45A 2HYVA 1BCYA 1BCZA 2H0LA 2XO2A 4MDVA 4EVFA 1ANNA 2H0MA 1AOWA 1HVFA
chains in the Genus database with same CATH superfamily
1AXNA 1AOWA 1XJLA 1R8QE 2HYUA 2ZOCA 3ABSA 1MCXA 1Q8DA 3USYA 3L8NA 1HM6A 1A8BA 4X9PA 1XT0B 4FQ0C 1PBVA 4HREA 4D7QA 2RANA 1BC9A 1A8AA 1BC3A 1RE0B 1N42A 3ABQA 1UPTB 1BCZA 2H0LA 4EVFA 2OY9A 2VXGA 3AJCA 1HVFA 1SAVA 1S9DE 1XSZA 1BO9A 4C0AA 1YIIA 1BC0A 1YJ0A 1M9IA 1YGMA 3SWVA 4Q2SA 3AO0A 4JXHA 1G5NA 2R0DA 1ANWA 1BCWA 2IE7A 4EVHA 1AVRA 2H0KA 1N41A 1HAKA 1AIIA 2ZHJA 4Z21A 1AVCA 4JMOA 2HYVA 1BCYA 3ANYA 2K6XA 3USWA 1N00A 4MDUA 1I4AA 1YCNA 2ZHIA 1ANXA 1R4AE 1BC1A 3ABRA 4FHRB 2XO3A 1HVEA 4D7RA 1N44A 4OIYA 1R8ME 3TW5A 3SOHB 4JK1X 1QC7A 4JMIA 2IICA 1W45A 4MDVA 2HSNA 1ANNA 4A4PA 1R8SE 2II2A 3LTLA 1HVDA 2Q4CA 1AEIA 3BRXA 1AVHA 4KN7X 4L5MA 2IE6A 4KN4X 1LKVX 1C1KA 1DK5A 1W3WA 1W7BA 2HYWA 4JWLA 1ALAA 1KU1A 1DM5A 1HVGA 4C7PA 2XO2A 3HJLA 3ABOA 2H0MA 2QEZA 2R09A 4KMUX
chains in the Genus database with same CATH topology
1SAVA 1N00A 2II2A 1AXNA 1I4AA 4MDUA 1XJLA 1YCNA 1HVDA 2ZHIA 1BO9A 1ANXA 2HYUA 1YIIA 2ZOCA 1BC0A 1MCXA 1YJ0A 1M9IA 2Q4CA 1AEIA 1BC1A 1HM6A 3BRXA 1A8BA 1AVHA 4X9PA 2IE6A 1G5NA 4HREA 1ANWA 2HYWA 1BCWA 1DK5A 1W3WA 1W7BA 2RANA 1HVEA 2XO3A 1N44A 2IE7A 4EVHA 1AVRA 2H0KA 1BC3A 1ALAA 1A8AA 1HAKA 1N41A 1N42A 1AIIA 2ZHJA 1DM5A 1HVGA 2IICA 1AVCA 1W45A 2HYVA 1BCYA 1BCZA 2H0LA 2XO2A 4MDVA 4EVFA 1ANNA 2H0MA 1AOWA 1HVFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SAV A;  1N00 A;  2II2 A;  1AXN A;  1I4A A;  4MDU A;  1XJL A;  1YCN A;  1HVD A;  2ZHI A;  1BO9 A;  1ANX A;  2HYU A;  1YII A;  2ZOC A;  1BC0 A;  1MCX A;  1YJ0 A;  1M9I A;  2Q4C A;  1AEI A;  1BC1 A;  1HM6 A;  3BRX A;  1A8B A;  1AVH A;  4X9P A;  2IE6 A;  1G5N A;  4HRE A;  1ANW A;  2HYW A;  1BCW A;  1DK5 A;  1W3W A;  1W7B A;  2RAN A;  1HVE A;  2XO3 A;  1N44 A;  2IE7 A;  4EVH A;  1AVR A;  2H0K A;  1BC3 A;  1ALA A;  1A8A A;  1HAK A;  1N41 A;  1N42 A;  1AII A;  2ZHJ A;  1DM5 A;  1HVG A;  2IIC A;  1AVC A;  1W45 A;  2HYV A;  1BCY A;  1BCZ A;  2H0L A;  2XO2 A;  4MDV A;  4EVF A;  1ANN A;  2H0M A;  1AOW A;  1HVF A; 
#chains in the Genus database with same CATH topology
 1AXN A;  1AOW A;  1XJL A;  1R8Q E;  2HYU A;  2ZOC A;  3ABS A;  1MCX A;  1Q8D A;  3USY A;  3L8N A;  1HM6 A;  1A8B A;  4X9P A;  1XT0 B;  4FQ0 C;  1PBV A;  4HRE A;  4D7Q A;  2RAN A;  1BC9 A;  1A8A A;  1BC3 A;  1RE0 B;  1N42 A;  3ABQ A;  1UPT B;  1BCZ A;  2H0L A;  4EVF A;  2OY9 A;  2VXG A;  3AJC A;  1HVF A;  1SAV A;  1S9D E;  1XSZ A;  1BO9 A;  4C0A A;  1YII A;  1BC0 A;  1YJ0 A;  1M9I A;  1YGM A;  3SWV A;  4Q2S A;  3AO0 A;  4JXH A;  1G5N A;  2R0D A;  1ANW A;  1BCW A;  2IE7 A;  4EVH A;  1AVR A;  2H0K A;  1N41 A;  1HAK A;  1AII A;  2ZHJ A;  4Z21 A;  1AVC A;  4JMO A;  2HYV A;  1BCY A;  3ANY A;  2K6X A;  3USW A;  1N00 A;  4MDU A;  1I4A A;  1YCN A;  2ZHI A;  1ANX A;  1R4A E;  1BC1 A;  3ABR A;  4FHR B;  2XO3 A;  1HVE A;  4D7R A;  1N44 A;  4OIY A;  1R8M E;  3TW5 A;  3SOH B;  4JK1 X;  1QC7 A;  4JMI A;  2IIC A;  1W45 A;  4MDV A;  2HSN A;  1ANN A;  4A4P A;  1R8S E;  2II2 A;  3LTL A;  1HVD A;  2Q4C A;  1AEI A;  3BRX A;  1AVH A;  4KN7 X;  4L5M A;  2IE6 A;  4KN4 X;  1LKV X;  1C1K A;  1DK5 A;  1W3W A;  1W7B A;  2HYW A;  4JWL A;  1ALA A;  1KU1 A;  1DM5 A;  1HVG A;  4C7P A;  2XO2 A;  3HJL A;  3ABO A;  2H0M A;  2QEZ A;  2R09 A;  4KMU X; 
#chains in the Genus database with same CATH homology
 1SAV A;  1N00 A;  2II2 A;  1AXN A;  1I4A A;  4MDU A;  1XJL A;  1YCN A;  1HVD A;  2ZHI A;  1BO9 A;  1ANX A;  2HYU A;  1YII A;  2ZOC A;  1BC0 A;  1MCX A;  1YJ0 A;  1M9I A;  2Q4C A;  1AEI A;  1BC1 A;  1HM6 A;  3BRX A;  1A8B A;  1AVH A;  4X9P A;  2IE6 A;  1G5N A;  4HRE A;  1ANW A;  2HYW A;  1BCW A;  1DK5 A;  1W3W A;  1W7B A;  2RAN A;  1HVE A;  2XO3 A;  1N44 A;  2IE7 A;  4EVH A;  1AVR A;  2H0K A;  1BC3 A;  1ALA A;  1A8A A;  1HAK A;  1N41 A;  1N42 A;  1AII A;  2ZHJ A;  1DM5 A;  1HVG A;  2IIC A;  1AVC A;  1W45 A;  2HYV A;  1BCY A;  1BCZ A;  2H0L A;  2XO2 A;  4MDV A;  4EVF A;  1ANN A;  2H0M A;  1AOW A;  1HVF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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