1AVH | Genus

Total Genus 120

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	120
sequence length	318
structure length	318
Chain Sequence	QVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 318 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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318 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Calcium/phospholipid binding
source organism	Homo sapiens
publication title	Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins. pubmed doi rcsb
molecule keywords	ANNEXIN V
total genus	120
structure length	318
sequence length	318
chains with identical sequence	B
ec nomenclature
pdb deposition date	1991-10-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00191	Annexin	Annexin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1avhA02
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1avhA04
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1avhA01
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1avhA03

1HVGA 1M9IA 2IE7A 4EVHA 1ALAA 1BCZA 1AVCA 1DK5A 1BC3A 1AIIA 1HVFA 1N00A 2H0LA 2HYVA 1ANNA 1AVRA 1W3WA 2ZOCA 2IE6A 4HREA 2ZHJA 2RANA 1AVHA 1HVDA 3BRXA 1DM5A 1N44A 2II2A 1YCNA 4MDVA 1HM6A 1YJ0A 4EVFA 1HAKA 1XJLA 2ZHIA 1AEIA 1N42A 1HVEA 4X9PA 2HYUA 1A8AA 1MCXA 1BO9A 1N41A 1A8BA 1I4AA 1ANXA 1AXNA 1W45A 1BCWA 1G5NA 2H0KA 2Q4CA 2IICA 1W7BA 1AOWA 2HYWA 4MDUA 1BCYA 1SAVA 1ANWA 1BC0A 1YIIA 2XO2A 1BC1A 2XO3A 2H0MA
chains in the Genus database with same CATH superfamily

4OIYA 2HSNA 1ALAA 1HVFA 1N00A 3ABOA 3ANYA 4JXHA 1HVDA 3BRXA 1DM5A 1N44A 3L8NA 1YCNA 1RE0B 1YJ0A 1LKVX 1XJLA 1R4AE 2QEZA 4JMOA 1N42A 4FHRB 1MCXA 2VXGA 1W45A 2H0KA 1G5NA 4A4PA 2K6XA 4JWLA 2H0LA 2XO2A 1AIIA 1HM6A 2H0MA 1M9IA 1AVCA 4FQ0C 2R09A 1R8ME 1QC7A 1AVRA 1W3WA 4HREA 2IE6A 2RANA 1AVHA 4D7QA 3AO0A 4MDVA 1PBVA 1HVEA 2HYUA 1A8AA 4KMUX 3HJLA 1XSZA 1BCWA 3USYA 1AOWA 3USWA 1BC9A 4C0AA 1ANWA 1BC0A 1YGMA 2XO3A 2IE7A 4Q2SA 1DK5A 2R0DA 2HYVA 4Z21A 1ANNA 4L5MA 4C7PA 1HAKA 2ZHIA 1AEIA 4X9PA 1BO9A 1A8BA 1XT0B 1ANXA 1AXNA 2Q4CA 2IICA 4D7RA 1S9DE 2HYWA 4MDUA 2ZHJA 1BC1A 1HVGA 4EVHA 3SOHB 1BCZA 3ABQA 3ABRA 1BC3A 4KN4X 2ZOCA 2OY9A 2II2A 4JMIA 4EVFA 3AJCA 1R8SE 1Q8DA 1R8QE 3LTLA 4JK1X 3TW5A 1KU1A 1UPTB 1N41A 1I4AA 4KN7X 3ABSA 1W7BA 3SWVA 1C1KA 1BCYA 1SAVA 1YIIA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1HVG A;  1M9I A;  2IE7 A;  4EVH A;  1ALA A;  1BCZ A;  1AVC A;  1DK5 A;  1BC3 A;  1AII A;  1HVF A;  1N00 A;  2H0L A;  2HYV A;  1ANN A;  1AVR A;  1W3W A;  2ZOC A;  2IE6 A;  4HRE A;  2ZHJ A;  2RAN A;  1AVH A;  1HVD A;  3BRX A;  1DM5 A;  1N44 A;  2II2 A;  1YCN A;  4MDV A;  1HM6 A;  1YJ0 A;  4EVF A;  1HAK A;  1XJL A;  2ZHI A;  1AEI A;  1N42 A;  1HVE A;  4X9P A;  2HYU A;  1A8A A;  1MCX A;  1BO9 A;  1N41 A;  1A8B A;  1I4A A;  1ANX A;  1AXN A;  1W45 A;  1BCW A;  1G5N A;  2H0K A;  2Q4C A;  2IIC A;  1W7B A;  1AOW A;  2HYW A;  4MDU A;  1BCY A;  1SAV A;  1ANW A;  1BC0 A;  1YII A;  2XO2 A;  1BC1 A;  2XO3 A;  2H0M A; 
#chains in the Genus database with same CATH topology
 4OIY A;  2HSN A;  1ALA A;  1HVF A;  1N00 A;  3ABO A;  3ANY A;  4JXH A;  1HVD A;  3BRX A;  1DM5 A;  1N44 A;  3L8N A;  1YCN A;  1RE0 B;  1YJ0 A;  1LKV X;  1XJL A;  1R4A E;  2QEZ A;  4JMO A;  1N42 A;  4FHR B;  1MCX A;  2VXG A;  1W45 A;  2H0K A;  1G5N A;  4A4P A;  2K6X A;  4JWL A;  2H0L A;  2XO2 A;  1AII A;  1HM6 A;  2H0M A;  1M9I A;  1AVC A;  4FQ0 C;  2R09 A;  1R8M E;  1QC7 A;  1AVR A;  1W3W A;  4HRE A;  2IE6 A;  2RAN A;  1AVH A;  4D7Q A;  3AO0 A;  4MDV A;  1PBV A;  1HVE A;  2HYU A;  1A8A A;  4KMU X;  3HJL A;  1XSZ A;  1BCW A;  3USY A;  1AOW A;  3USW A;  1BC9 A;  4C0A A;  1ANW A;  1BC0 A;  1YGM A;  2XO3 A;  2IE7 A;  4Q2S A;  1DK5 A;  2R0D A;  2HYV A;  4Z21 A;  1ANN A;  4L5M A;  4C7P A;  1HAK A;  2ZHI A;  1AEI A;  4X9P A;  1BO9 A;  1A8B A;  1XT0 B;  1ANX A;  1AXN A;  2Q4C A;  2IIC A;  4D7R A;  1S9D E;  2HYW A;  4MDU A;  2ZHJ A;  1BC1 A;  1HVG A;  4EVH A;  3SOH B;  1BCZ A;  3ABQ A;  3ABR A;  1BC3 A;  4KN4 X;  2ZOC A;  2OY9 A;  2II2 A;  4JMI A;  4EVF A;  3AJC A;  1R8S E;  1Q8D A;  1R8Q E;  3LTL A;  4JK1 X;  3TW5 A;  1KU1 A;  1UPT B;  1N41 A;  1I4A A;  4KN7 X;  3ABS A;  1W7B A;  3SWV A;  1C1K A;  1BCY A;  1SAV A;  1YII A; 
#chains in the Genus database with same CATH homology
 1HVG A;  1M9I A;  2IE7 A;  4EVH A;  1ALA A;  1BCZ A;  1AVC A;  1DK5 A;  1BC3 A;  1AII A;  1HVF A;  1N00 A;  2H0L A;  2HYV A;  1ANN A;  1AVR A;  1W3W A;  2ZOC A;  2IE6 A;  4HRE A;  2ZHJ A;  2RAN A;  1AVH A;  1HVD A;  3BRX A;  1DM5 A;  1N44 A;  2II2 A;  1YCN A;  4MDV A;  1HM6 A;  1YJ0 A;  4EVF A;  1HAK A;  1XJL A;  2ZHI A;  1AEI A;  1N42 A;  1HVE A;  4X9P A;  2HYU A;  1A8A A;  1MCX A;  1BO9 A;  1N41 A;  1A8B A;  1I4A A;  1ANX A;  1AXN A;  1W45 A;  1BCW A;  1G5N A;  2H0K A;  2Q4C A;  2IIC A;  1W7B A;  1AOW A;  2HYW A;  4MDU A;  1BCY A;  1SAV A;  1ANW A;  1BC0 A;  1YII A;  2XO2 A;  1BC1 A;  2XO3 A;  2H0M A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1AVHA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations