1AVHA

Crystal and molecular structure of human annexin v after refinement. implications for structure, membrane binding and ion channel formation of the annexin family of proteins
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
318
structure length
318
Chain Sequence
QVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins.
pubmed doi rcsb
molecule tags Calcium/phospholipid binding
source organism Homo sapiens
molecule keywords ANNEXIN V
total genus 120
structure length 318
sequence length 318
chains with identical sequence B
ec nomenclature
pdb deposition date 1991-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1avhA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1avhA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1avhA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1avhA03
1ANXA 2IE7A 1BC1A 2Q4CA 1I4AA 1BC3A 1AXNA 2RANA 1ANWA 1BC0A 1A8AA 4HREA 2II2A 1DK5A 1AEIA 2IE6A 2ZOCA 1ANNA 1AOWA 1ALAA 1AVCA 1W45A 4EVHA 2XO2A 4MDUA 1AVHA 1YJ0A 1G5NA 2IICA 2H0MA 2XO3A 1HVGA 4X9PA 2H0KA 1YIIA 1BCWA 1BO9A 1W7BA 1N42A 1HAKA 4EVFA 1HVEA 1HVDA 1HVFA 1N44A 2H0LA 2HYUA 1DM5A 1XJLA 1BCYA 1N00A 1N41A 1M9IA 1W3WA 1A8BA 1BCZA 1SAVA 2HYVA 2ZHIA 4MDVA 1AVRA 1YCNA 3BRXA 2HYWA 2ZHJA 1MCXA 1AIIA 1HM6A
chains in the Genus database with same CATH superfamily
3L8NA 1R8ME 1XSZA 1A8AA 2II2A 3AJCA 1DK5A 2QEZA 1ANNA 1AOWA 1AVCA 2VXGA 1W45A 1PBVA 1AVHA 1YGMA 4Q2SA 1HVEA 1N44A 1RE0B 2R0DA 2XO3A 1BCYA 1N41A 4MDVA 1A8BA 1BCZA 1BC9A 1SAVA 2HYVA 3BRXA 2HSNA 4C7PA 1UPTB 4L5MA 1I4AA 4KMUX 1AXNA 2RANA 1BC0A 1R8QE 4KN4X 1R8SE 2ZOCA 3AO0A 4JMOA 2XO2A 4C0AA 3ABQA 1G5NA 2IICA 3ANYA 4Z21A 4X9PA 3ABRA 4D7QA 4EVFA 1R4AE 1HVDA 1Q8DA 1C1KA 4FHRB 1M9IA 1XT0B 2ZHIA 3LTLA 1AVRA 1QC7A 2OY9A 3ABOA 1S9DE 4JMIA 3HJLA 4EVHA 3SOHB 1ALAA 4A4PA 1YJ0A 2K6XA 2H0MA 2H0KA 1BCWA 1KU1A 4JK1X 1N42A 1LKVX 1HVFA 1XJLA 1N00A 4FQ0C 3USYA 2HYWA 1AIIA 2IE6A 1ANXA 2IE7A 1BC1A 2Q4CA 3ABSA 1BC3A 3USWA 1ANWA 4HREA 4D7RA 1AEIA 4MDUA 2R09A 4OIYA 1HVGA 4JWLA 1YIIA 1BO9A 1W7BA 3TW5A 1HAKA 2H0LA 2HYUA 1DM5A 1W3WA 4KN7X 4JXHA 1YCNA 2ZHJA 3SWVA 1MCXA 1HM6A
chains in the Genus database with same CATH topology
1ANXA 2IE7A 1BC1A 2Q4CA 1I4AA 1BC3A 1AXNA 2RANA 1ANWA 1BC0A 1A8AA 4HREA 2II2A 1DK5A 1AEIA 2IE6A 2ZOCA 1ANNA 1AOWA 1ALAA 1AVCA 1W45A 4EVHA 2XO2A 4MDUA 1AVHA 1YJ0A 1G5NA 2IICA 2H0MA 2XO3A 1HVGA 4X9PA 2H0KA 1YIIA 1BCWA 1BO9A 1W7BA 1N42A 1HAKA 4EVFA 1HVEA 1HVDA 1HVFA 1N44A 2H0LA 2HYUA 1DM5A 1XJLA 1BCYA 1N00A 1N41A 1M9IA 1W3WA 1A8BA 1BCZA 1SAVA 2HYVA 2ZHIA 4MDVA 1AVRA 1YCNA 3BRXA 2HYWA 2ZHJA 1MCXA 1AIIA 1HM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ANX A;  2IE7 A;  1BC1 A;  2Q4C A;  1I4A A;  1BC3 A;  1AXN A;  2RAN A;  1ANW A;  1BC0 A;  1A8A A;  4HRE A;  2II2 A;  1DK5 A;  1AEI A;  2IE6 A;  2ZOC A;  1ANN A;  1AOW A;  1ALA A;  1AVC A;  1W45 A;  4EVH A;  2XO2 A;  4MDU A;  1AVH A;  1YJ0 A;  1G5N A;  2IIC A;  2H0M A;  2XO3 A;  1HVG A;  4X9P A;  2H0K A;  1YII A;  1BCW A;  1BO9 A;  1W7B A;  1N42 A;  1HAK A;  4EVF A;  1HVE A;  1HVD A;  1HVF A;  1N44 A;  2H0L A;  2HYU A;  1DM5 A;  1XJL A;  1BCY A;  1N00 A;  1N41 A;  1M9I A;  1W3W A;  1A8B A;  1BCZ A;  1SAV A;  2HYV A;  2ZHI A;  4MDV A;  1AVR A;  1YCN A;  3BRX A;  2HYW A;  2ZHJ A;  1MCX A;  1AII A;  1HM6 A; 
#chains in the Genus database with same CATH topology
 3L8N A;  1R8M E;  1XSZ A;  1A8A A;  2II2 A;  3AJC A;  1DK5 A;  2QEZ A;  1ANN A;  1AOW A;  1AVC A;  2VXG A;  1W45 A;  1PBV A;  1AVH A;  1YGM A;  4Q2S A;  1HVE A;  1N44 A;  1RE0 B;  2R0D A;  2XO3 A;  1BCY A;  1N41 A;  4MDV A;  1A8B A;  1BCZ A;  1BC9 A;  1SAV A;  2HYV A;  3BRX A;  2HSN A;  4C7P A;  1UPT B;  4L5M A;  1I4A A;  4KMU X;  1AXN A;  2RAN A;  1BC0 A;  1R8Q E;  4KN4 X;  1R8S E;  2ZOC A;  3AO0 A;  4JMO A;  2XO2 A;  4C0A A;  3ABQ A;  1G5N A;  2IIC A;  3ANY A;  4Z21 A;  4X9P A;  3ABR A;  4D7Q A;  4EVF A;  1R4A E;  1HVD A;  1Q8D A;  1C1K A;  4FHR B;  1M9I A;  1XT0 B;  2ZHI A;  3LTL A;  1AVR A;  1QC7 A;  2OY9 A;  3ABO A;  1S9D E;  4JMI A;  3HJL A;  4EVH A;  3SOH B;  1ALA A;  4A4P A;  1YJ0 A;  2K6X A;  2H0M A;  2H0K A;  1BCW A;  1KU1 A;  4JK1 X;  1N42 A;  1LKV X;  1HVF A;  1XJL A;  1N00 A;  4FQ0 C;  3USY A;  2HYW A;  1AII A;  2IE6 A;  1ANX A;  2IE7 A;  1BC1 A;  2Q4C A;  3ABS A;  1BC3 A;  3USW A;  1ANW A;  4HRE A;  4D7R A;  1AEI A;  4MDU A;  2R09 A;  4OIY A;  1HVG A;  4JWL A;  1YII A;  1BO9 A;  1W7B A;  3TW5 A;  1HAK A;  2H0L A;  2HYU A;  1DM5 A;  1W3W A;  4KN7 X;  4JXH A;  1YCN A;  2ZHJ A;  3SWV A;  1MCX A;  1HM6 A; 
#chains in the Genus database with same CATH homology
 1ANX A;  2IE7 A;  1BC1 A;  2Q4C A;  1I4A A;  1BC3 A;  1AXN A;  2RAN A;  1ANW A;  1BC0 A;  1A8A A;  4HRE A;  2II2 A;  1DK5 A;  1AEI A;  2IE6 A;  2ZOC A;  1ANN A;  1AOW A;  1ALA A;  1AVC A;  1W45 A;  4EVH A;  2XO2 A;  4MDU A;  1AVH A;  1YJ0 A;  1G5N A;  2IIC A;  2H0M A;  2XO3 A;  1HVG A;  4X9P A;  2H0K A;  1YII A;  1BCW A;  1BO9 A;  1W7B A;  1N42 A;  1HAK A;  4EVF A;  1HVE A;  1HVD A;  1HVF A;  1N44 A;  2H0L A;  2HYU A;  1DM5 A;  1XJL A;  1BCY A;  1N00 A;  1N41 A;  1M9I A;  1W3W A;  1A8B A;  1BCZ A;  1SAV A;  2HYV A;  2ZHI A;  4MDV A;  1AVR A;  1YCN A;  3BRX A;  2HYW A;  2ZHJ A;  1MCX A;  1AII A;  1HM6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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