1BC3A

Recombinant rat annexin v, triple mutant (t72k, s144k, s228k)
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
318
structure length
318
Chain Sequence
ALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELKGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTKGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETKGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
pubmed doi rcsb
molecule tags Calcium-binding protein
source organism Rattus norvegicus
molecule keywords ANNEXIN V
total genus 131
structure length 318
sequence length 318
ec nomenclature
pdb deposition date 1998-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bc3A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bc3A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bc3A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bc3A03
1AOWA 1BC3A 1BC0A 1N00A 1HVGA 1HVEA 2H0MA 3BRXA 2ZHJA 4MDVA 1AXNA 2XO2A 1A8BA 2H0KA 2H0LA 1M9IA 2HYUA 2II2A 2RANA 4EVFA 1ANNA 1HM6A 1N44A 2Q4CA 1W7BA 1BCWA 1MCXA 1AEIA 4HREA 1SAVA 1AVRA 2ZOCA 1YIIA 1DK5A 1YJ0A 1A8AA 2ZHIA 2IICA 1YCNA 1I4AA 2IE7A 1N42A 4X9PA 4EVHA 1ANWA 1BCYA 1AVCA 1ALAA 1W45A 1DM5A 2HYVA 1N41A 1AIIA 1G5NA 1HAKA 1XJLA 2HYWA 1W3WA 1BCZA 4MDUA 1BO9A 1HVDA 2IE6A 2XO3A 1ANXA 1HVFA 1AVHA 1BC1A
chains in the Genus database with same CATH superfamily
1AOWA 1PBVA 1BC0A 1HVEA 2H0MA 2ZHJA 2HSNA 2HYUA 1M9IA 4EVFA 1ANNA 1N44A 3SOHB 3USWA 4JMIA 1BC9A 1MCXA 2R09A 4JWLA 1YIIA 4KN4X 2IICA 4EVHA 3LTLA 1AIIA 1UPTB 1BCZA 4MDUA 4D7QA 1HVDA 1BC3A 1N00A 1HVGA 1AXNA 1A8BA 1R8QE 2H0LA 2II2A 1HM6A 4A4PA 1W7BA 3SWVA 3ABSA 4FQ0C 4HREA 1SAVA 1AVRA 1DK5A 3AO0A 1YCNA 1N42A 1ANWA 1W45A 4C0AA 1XJLA 1W3WA 4JMOA 1BO9A 1KU1A 3ABOA 2XO3A 1R8SE 1BC1A 1S9DE 2QEZA 4X9PA 1Q8DA 3BRXA 2XO2A 1XSZA 2RANA 4L5MA 2Q4CA 1BCWA 3TW5A 1AEIA 1C1KA 4JK1X 2R0DA 1A8AA 3HJLA 1BCYA 1AVCA 1DM5A 1N41A 1HAKA 3USYA 1QC7A 2K6XA 1R4AE 4OIYA 4FHRB 2IE6A 3ANYA 2ZHIA 1ANXA 4JXHA 1AVHA 1LKVX 3L8NA 4MDVA 3ABQA 4Q2SA 1YGMA 3ABRA 4Z21A 1R8ME 2ZOCA 1YJ0A 4KN7X 1I4AA 2IE7A 2OY9A 1RE0B 3AJCA 1XT0B 1ALAA 2HYVA 2VXGA 4KMUX 4C7PA 4D7RA 1G5NA 2HYWA 1HVFA 2H0KA
chains in the Genus database with same CATH topology
1AOWA 1BC3A 1BC0A 1N00A 1HVGA 1HVEA 2H0MA 3BRXA 2ZHJA 4MDVA 1AXNA 2XO2A 1A8BA 2H0KA 2H0LA 1M9IA 2HYUA 2II2A 2RANA 4EVFA 1ANNA 1HM6A 1N44A 2Q4CA 1W7BA 1BCWA 1MCXA 1AEIA 4HREA 1SAVA 1AVRA 2ZOCA 1YIIA 1DK5A 1YJ0A 1A8AA 2ZHIA 2IICA 1YCNA 1I4AA 2IE7A 1N42A 4X9PA 4EVHA 1ANWA 1BCYA 1AVCA 1ALAA 1W45A 1DM5A 2HYVA 1N41A 1AIIA 1G5NA 1HAKA 1XJLA 2HYWA 1W3WA 1BCZA 4MDUA 1BO9A 1HVDA 2IE6A 2XO3A 1ANXA 1HVFA 1AVHA 1BC1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AOW A;  1BC3 A;  1BC0 A;  1N00 A;  1HVG A;  1HVE A;  2H0M A;  3BRX A;  2ZHJ A;  4MDV A;  1AXN A;  2XO2 A;  1A8B A;  2H0K A;  2H0L A;  1M9I A;  2HYU A;  2II2 A;  2RAN A;  4EVF A;  1ANN A;  1HM6 A;  1N44 A;  2Q4C A;  1W7B A;  1BCW A;  1MCX A;  1AEI A;  4HRE A;  1SAV A;  1AVR A;  2ZOC A;  1YII A;  1DK5 A;  1YJ0 A;  1A8A A;  2ZHI A;  2IIC A;  1YCN A;  1I4A A;  2IE7 A;  1N42 A;  4X9P A;  4EVH A;  1ANW A;  1BCY A;  1AVC A;  1ALA A;  1W45 A;  1DM5 A;  2HYV A;  1N41 A;  1AII A;  1G5N A;  1HAK A;  1XJL A;  2HYW A;  1W3W A;  1BCZ A;  4MDU A;  1BO9 A;  1HVD A;  2IE6 A;  2XO3 A;  1ANX A;  1HVF A;  1AVH A;  1BC1 A; 
#chains in the Genus database with same CATH topology
 1AOW A;  1PBV A;  1BC0 A;  1HVE A;  2H0M A;  2ZHJ A;  2HSN A;  2HYU A;  1M9I A;  4EVF A;  1ANN A;  1N44 A;  3SOH B;  3USW A;  4JMI A;  1BC9 A;  1MCX A;  2R09 A;  4JWL A;  1YII A;  4KN4 X;  2IIC A;  4EVH A;  3LTL A;  1AII A;  1UPT B;  1BCZ A;  4MDU A;  4D7Q A;  1HVD A;  1BC3 A;  1N00 A;  1HVG A;  1AXN A;  1A8B A;  1R8Q E;  2H0L A;  2II2 A;  1HM6 A;  4A4P A;  1W7B A;  3SWV A;  3ABS A;  4FQ0 C;  4HRE A;  1SAV A;  1AVR A;  1DK5 A;  3AO0 A;  1YCN A;  1N42 A;  1ANW A;  1W45 A;  4C0A A;  1XJL A;  1W3W A;  4JMO A;  1BO9 A;  1KU1 A;  3ABO A;  2XO3 A;  1R8S E;  1BC1 A;  1S9D E;  2QEZ A;  4X9P A;  1Q8D A;  3BRX A;  2XO2 A;  1XSZ A;  2RAN A;  4L5M A;  2Q4C A;  1BCW A;  3TW5 A;  1AEI A;  1C1K A;  4JK1 X;  2R0D A;  1A8A A;  3HJL A;  1BCY A;  1AVC A;  1DM5 A;  1N41 A;  1HAK A;  3USY A;  1QC7 A;  2K6X A;  1R4A E;  4OIY A;  4FHR B;  2IE6 A;  3ANY A;  2ZHI A;  1ANX A;  4JXH A;  1AVH A;  1LKV X;  3L8N A;  4MDV A;  3ABQ A;  4Q2S A;  1YGM A;  3ABR A;  4Z21 A;  1R8M E;  2ZOC A;  1YJ0 A;  4KN7 X;  1I4A A;  2IE7 A;  2OY9 A;  1RE0 B;  3AJC A;  1XT0 B;  1ALA A;  2HYV A;  2VXG A;  4KMU X;  4C7P A;  4D7R A;  1G5N A;  2HYW A;  1HVF A;  2H0K A; 
#chains in the Genus database with same CATH homology
 1AOW A;  1BC3 A;  1BC0 A;  1N00 A;  1HVG A;  1HVE A;  2H0M A;  3BRX A;  2ZHJ A;  4MDV A;  1AXN A;  2XO2 A;  1A8B A;  2H0K A;  2H0L A;  1M9I A;  2HYU A;  2II2 A;  2RAN A;  4EVF A;  1ANN A;  1HM6 A;  1N44 A;  2Q4C A;  1W7B A;  1BCW A;  1MCX A;  1AEI A;  4HRE A;  1SAV A;  1AVR A;  2ZOC A;  1YII A;  1DK5 A;  1YJ0 A;  1A8A A;  2ZHI A;  2IIC A;  1YCN A;  1I4A A;  2IE7 A;  1N42 A;  4X9P A;  4EVH A;  1ANW A;  1BCY A;  1AVC A;  1ALA A;  1W45 A;  1DM5 A;  2HYV A;  1N41 A;  1AII A;  1G5N A;  1HAK A;  1XJL A;  2HYW A;  1W3W A;  1BCZ A;  4MDU A;  1BO9 A;  1HVD A;  2IE6 A;  2XO3 A;  1ANX A;  1HVF A;  1AVH A;  1BC1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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