1BCWA

Recombinant rat annexin v, t72a mutant
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
318
structure length
318
Chain Sequence
ALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELAGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
pubmed doi rcsb
molecule tags Calcium-binding protein
source organism Rattus norvegicus
molecule keywords ANNEXIN V
total genus 128
structure length 318
sequence length 318
ec nomenclature
pdb deposition date 1998-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bcwA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bcwA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bcwA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1bcwA03
1BC3A 1AXNA 1N00A 2RANA 1HVGA 2ZOCA 4EVHA 1AOWA 1YCNA 2Q4CA 1BO9A 1I4AA 1ANNA 1BCZA 1G5NA 1HVEA 2HYUA 1W3WA 1BC1A 2IE7A 1AVRA 1W45A 1XJLA 1HVDA 1N41A 1M9IA 4MDVA 1A8BA 1W7BA 1HM6A 1BCWA 2HYVA 2II2A 2H0LA 1AEIA 2ZHJA 3BRXA 2H0KA 2HYWA 1DK5A 1DM5A 1AIIA 4MDUA 1MCXA 2XO3A 2IE6A 1A8AA 4HREA 1AVHA 1BC0A 1ALAA 4X9PA 1SAVA 1BCYA 4EVFA 1HVFA 1HAKA 1N42A 2XO2A 2ZHIA 1ANWA 1YIIA 1N44A 1ANXA 1AVCA 2IICA 1YJ0A 2H0MA
chains in the Genus database with same CATH superfamily
1BC3A 1N00A 4JXHA 4D7QA 3HJLA 1YCNA 3ABQA 1BO9A 4D7RA 2HYUA 3LTLA 4FHRB 1W3WA 1HVDA 1N41A 3AJCA 4MDVA 1W7BA 2II2A 4JMIA 4JWLA 4MDUA 3ABOA 1MCXA 2IE6A 4X9PA 1AVHA 1ALAA 1SAVA 1S9DE 2VXGA 4KMUX 1AVCA 2RANA 1AXNA 4EVHA 2Q4CA 3ABRA 1BCZA 4A4PA 3TW5A 2IE7A 3USYA 4FQ0C 1HM6A 1AEIA 1UPTB 1R8QE 2ZHJA 2H0KA 3BRXA 1C1KA 1Q8DA 4HREA 1BC0A 1N42A 1XT0B 3L8NA 2ZHIA 3ANYA 3AO0A 2IICA 2OY9A 1XSZA 2ZOCA 1HVGA 4KN7X 2K6XA 1ANNA 1BC1A 1R8SE 1AVRA 4Z21A 1W45A 1XJLA 4JK1X 4JMOA 1A8BA 2HYVA 1BCWA 1R4AE 2HYWA 1AIIA 4KN4X 1RE0B 2XO3A 2HSNA 1BCYA 1HVFA 1HAKA 2XO2A 1ANWA 1YIIA 1N44A 1QC7A 1YJ0A 4C0AA 2QEZA 3SOHB 1AOWA 4C7PA 1I4AA 1G5NA 1HVEA 1PBVA 1M9IA 1R8ME 2H0LA 1KU1A 1YGMA 1BC9A 1DK5A 1DM5A 3SWVA 3ABSA 1A8AA 2R0DA 4EVFA 4L5MA 3USWA 1LKVX 4Q2SA 1ANXA 2R09A 4OIYA 2H0MA
chains in the Genus database with same CATH topology
1BC3A 1AXNA 1N00A 2RANA 1HVGA 2ZOCA 4EVHA 1AOWA 1YCNA 2Q4CA 1BO9A 1I4AA 1ANNA 1BCZA 1G5NA 1HVEA 2HYUA 1W3WA 1BC1A 2IE7A 1AVRA 1W45A 1XJLA 1HVDA 1N41A 1M9IA 4MDVA 1A8BA 1W7BA 1HM6A 1BCWA 2HYVA 2II2A 2H0LA 1AEIA 2ZHJA 3BRXA 2H0KA 2HYWA 1DK5A 1DM5A 1AIIA 4MDUA 1MCXA 2XO3A 2IE6A 1A8AA 4HREA 1AVHA 1BC0A 1ALAA 4X9PA 1SAVA 1BCYA 4EVFA 1HVFA 1HAKA 1N42A 2XO2A 2ZHIA 1ANWA 1YIIA 1N44A 1ANXA 1AVCA 2IICA 1YJ0A 2H0MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BC3 A;  1AXN A;  1N00 A;  2RAN A;  1HVG A;  2ZOC A;  4EVH A;  1AOW A;  1YCN A;  2Q4C A;  1BO9 A;  1I4A A;  1ANN A;  1BCZ A;  1G5N A;  1HVE A;  2HYU A;  1W3W A;  1BC1 A;  2IE7 A;  1AVR A;  1W45 A;  1XJL A;  1HVD A;  1N41 A;  1M9I A;  4MDV A;  1A8B A;  1W7B A;  1HM6 A;  1BCW A;  2HYV A;  2II2 A;  2H0L A;  1AEI A;  2ZHJ A;  3BRX A;  2H0K A;  2HYW A;  1DK5 A;  1DM5 A;  1AII A;  4MDU A;  1MCX A;  2XO3 A;  2IE6 A;  1A8A A;  4HRE A;  1AVH A;  1BC0 A;  1ALA A;  4X9P A;  1SAV A;  1BCY A;  4EVF A;  1HVF A;  1HAK A;  1N42 A;  2XO2 A;  2ZHI A;  1ANW A;  1YII A;  1N44 A;  1ANX A;  1AVC A;  2IIC A;  1YJ0 A;  2H0M A; 
#chains in the Genus database with same CATH topology
 1BC3 A;  1N00 A;  4JXH A;  4D7Q A;  3HJL A;  1YCN A;  3ABQ A;  1BO9 A;  4D7R A;  2HYU A;  3LTL A;  4FHR B;  1W3W A;  1HVD A;  1N41 A;  3AJC A;  4MDV A;  1W7B A;  2II2 A;  4JMI A;  4JWL A;  4MDU A;  3ABO A;  1MCX A;  2IE6 A;  4X9P A;  1AVH A;  1ALA A;  1SAV A;  1S9D E;  2VXG A;  4KMU X;  1AVC A;  2RAN A;  1AXN A;  4EVH A;  2Q4C A;  3ABR A;  1BCZ A;  4A4P A;  3TW5 A;  2IE7 A;  3USY A;  4FQ0 C;  1HM6 A;  1AEI A;  1UPT B;  1R8Q E;  2ZHJ A;  2H0K A;  3BRX A;  1C1K A;  1Q8D A;  4HRE A;  1BC0 A;  1N42 A;  1XT0 B;  3L8N A;  2ZHI A;  3ANY A;  3AO0 A;  2IIC A;  2OY9 A;  1XSZ A;  2ZOC A;  1HVG A;  4KN7 X;  2K6X A;  1ANN A;  1BC1 A;  1R8S E;  1AVR A;  4Z21 A;  1W45 A;  1XJL A;  4JK1 X;  4JMO A;  1A8B A;  2HYV A;  1BCW A;  1R4A E;  2HYW A;  1AII A;  4KN4 X;  1RE0 B;  2XO3 A;  2HSN A;  1BCY A;  1HVF A;  1HAK A;  2XO2 A;  1ANW A;  1YII A;  1N44 A;  1QC7 A;  1YJ0 A;  4C0A A;  2QEZ A;  3SOH B;  1AOW A;  4C7P A;  1I4A A;  1G5N A;  1HVE A;  1PBV A;  1M9I A;  1R8M E;  2H0L A;  1KU1 A;  1YGM A;  1BC9 A;  1DK5 A;  1DM5 A;  3SWV A;  3ABS A;  1A8A A;  2R0D A;  4EVF A;  4L5M A;  3USW A;  1LKV X;  4Q2S A;  1ANX A;  2R09 A;  4OIY A;  2H0M A; 
#chains in the Genus database with same CATH homology
 1BC3 A;  1AXN A;  1N00 A;  2RAN A;  1HVG A;  2ZOC A;  4EVH A;  1AOW A;  1YCN A;  2Q4C A;  1BO9 A;  1I4A A;  1ANN A;  1BCZ A;  1G5N A;  1HVE A;  2HYU A;  1W3W A;  1BC1 A;  2IE7 A;  1AVR A;  1W45 A;  1XJL A;  1HVD A;  1N41 A;  1M9I A;  4MDV A;  1A8B A;  1W7B A;  1HM6 A;  1BCW A;  2HYV A;  2II2 A;  2H0L A;  1AEI A;  2ZHJ A;  3BRX A;  2H0K A;  2HYW A;  1DK5 A;  1DM5 A;  1AII A;  4MDU A;  1MCX A;  2XO3 A;  2IE6 A;  1A8A A;  4HRE A;  1AVH A;  1BC0 A;  1ALA A;  4X9P A;  1SAV A;  1BCY A;  4EVF A;  1HVF A;  1HAK A;  1N42 A;  2XO2 A;  2ZHI A;  1ANW A;  1YII A;  1N44 A;  1ANX A;  1AVC A;  2IIC A;  1YJ0 A;  2H0M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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