1DM5A

Annexin xii e105k homohexamer crystal structure
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
315
structure length
315
Chain Sequence
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQIKTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGLGTDKNALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLLVSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSYPQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAERLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADDCSGDYKDLLLQITGH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization.
pubmed doi rcsb
molecule tags Unknown function
source organism Hydra vulgaris
molecule keywords ANNEXIN XII E105K MUTANT HOMOHEXAMER
total genus 128
structure length 315
sequence length 315
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 1999-12-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1dm5A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1dm5A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1dm5A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1dm5A03
1AEIA 1MCXA 2H0MA 1N44A 1BCWA 1A8AA 1AOWA 1BC0A 1N00A 2ZHIA 1BO9A 1HVGA 4MDVA 2H0KA 1N42A 2HYVA 1HAKA 2XO3A 1ANWA 2H0LA 4EVFA 1HVEA 1BCYA 4MDUA 1YCNA 1HVFA 1SAVA 2IE6A 1DK5A 1W45A 1BC3A 1DM5A 1W7BA 1YJ0A 1XJLA 1AXNA 1N41A 1ALAA 1I4AA 1ANNA 2Q4CA 2ZOCA 1BC1A 1AVCA 2IE7A 1A8BA 2XO2A 1ANXA 1YIIA 2HYWA 2IICA 3BRXA 1BCZA 1W3WA 4X9PA 4EVHA 1M9IA 4HREA 1AVRA 1HVDA 2RANA 2ZHJA 2II2A 1AIIA 2HYUA 1HM6A 1G5NA 1AVHA
chains in the Genus database with same CATH superfamily
1AEIA 4JWLA 1MCXA 2H0MA 3TW5A 1AOWA 2ZHIA 1BO9A 3HJLA 2H0LA 3ABRA 1DK5A 1W45A 4JMIA 1C1KA 1AXNA 2K6XA 1I4AA 4FQ0C 2Q4CA 4D7RA 1BC1A 3LTLA 3ANYA 2OY9A 4KN7X 2IICA 4X9PA 1M9IA 1AVRA 1HVDA 2RANA 3AO0A 4FHRB 1N44A 1Q8DA 1A8AA 1RE0B 3USYA 4A4PA 1HVGA 4OIYA 2H0KA 1N42A 1ANWA 3L8NA 1BCYA 1R8ME 4JK1X 1HVFA 1BC9A 2IE6A 1XSZA 1DM5A 1XJLA 1AVCA 2IE7A 3ABSA 1A8BA 2HYWA 1BCZA 2VXGA 3USWA 4HREA 4Q2SA 3SWVA 2R09A 1AIIA 1R8QE 2XO2A 2QEZA 1BC0A 4Z21A 2HYVA 2XO3A 1PBVA 4KMUX 4KN4X 4EVFA 3ABOA 4MDUA 4D7QA 1SAVA 1W7BA 1YJ0A 1ALAA 2ZOCA 1R8SE 1ANXA 1YIIA 4EVHA 1S9DE 2II2A 1UPTB 3SOHB 2ZHJA 1G5NA 1AVHA 1QC7A 4JMOA 1BCWA 1N00A 4MDVA 1HAKA 4C0AA 3AJCA 1KU1A 1HVEA 3ABQA 1YCNA 1BC3A 1YGMA 4JXHA 2R0DA 1N41A 1ANNA 2HSNA 3BRXA 1XT0B 1W3WA 4C7PA 4L5MA 1R4AE 2HYUA 1LKVX 1HM6A
chains in the Genus database with same CATH topology
1AEIA 1MCXA 2H0MA 1N44A 1BCWA 1A8AA 1AOWA 1BC0A 1N00A 2ZHIA 1BO9A 1HVGA 4MDVA 2H0KA 1N42A 2HYVA 1HAKA 2XO3A 1ANWA 2H0LA 4EVFA 1HVEA 1BCYA 4MDUA 1YCNA 1HVFA 1SAVA 2IE6A 1DK5A 1W45A 1BC3A 1DM5A 1W7BA 1YJ0A 1XJLA 1AXNA 1N41A 1ALAA 1I4AA 1ANNA 2Q4CA 2ZOCA 1BC1A 1AVCA 2IE7A 1A8BA 2XO2A 1ANXA 1YIIA 2HYWA 2IICA 3BRXA 1BCZA 1W3WA 4X9PA 4EVHA 1M9IA 4HREA 1AVRA 1HVDA 2RANA 2ZHJA 2II2A 1AIIA 2HYUA 1HM6A 1G5NA 1AVHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AEI A;  1MCX A;  2H0M A;  1N44 A;  1BCW A;  1A8A A;  1AOW A;  1BC0 A;  1N00 A;  2ZHI A;  1BO9 A;  1HVG A;  4MDV A;  2H0K A;  1N42 A;  2HYV A;  1HAK A;  2XO3 A;  1ANW A;  2H0L A;  4EVF A;  1HVE A;  1BCY A;  4MDU A;  1YCN A;  1HVF A;  1SAV A;  2IE6 A;  1DK5 A;  1W45 A;  1BC3 A;  1DM5 A;  1W7B A;  1YJ0 A;  1XJL A;  1AXN A;  1N41 A;  1ALA A;  1I4A A;  1ANN A;  2Q4C A;  2ZOC A;  1BC1 A;  1AVC A;  2IE7 A;  1A8B A;  2XO2 A;  1ANX A;  1YII A;  2HYW A;  2IIC A;  3BRX A;  1BCZ A;  1W3W A;  4X9P A;  4EVH A;  1M9I A;  4HRE A;  1AVR A;  1HVD A;  2RAN A;  2ZHJ A;  2II2 A;  1AII A;  2HYU A;  1HM6 A;  1G5N A;  1AVH A; 
#chains in the Genus database with same CATH topology
 1AEI A;  4JWL A;  1MCX A;  2H0M A;  3TW5 A;  1AOW A;  2ZHI A;  1BO9 A;  3HJL A;  2H0L A;  3ABR A;  1DK5 A;  1W45 A;  4JMI A;  1C1K A;  1AXN A;  2K6X A;  1I4A A;  4FQ0 C;  2Q4C A;  4D7R A;  1BC1 A;  3LTL A;  3ANY A;  2OY9 A;  4KN7 X;  2IIC A;  4X9P A;  1M9I A;  1AVR A;  1HVD A;  2RAN A;  3AO0 A;  4FHR B;  1N44 A;  1Q8D A;  1A8A A;  1RE0 B;  3USY A;  4A4P A;  1HVG A;  4OIY A;  2H0K A;  1N42 A;  1ANW A;  3L8N A;  1BCY A;  1R8M E;  4JK1 X;  1HVF A;  1BC9 A;  2IE6 A;  1XSZ A;  1DM5 A;  1XJL A;  1AVC A;  2IE7 A;  3ABS A;  1A8B A;  2HYW A;  1BCZ A;  2VXG A;  3USW A;  4HRE A;  4Q2S A;  3SWV A;  2R09 A;  1AII A;  1R8Q E;  2XO2 A;  2QEZ A;  1BC0 A;  4Z21 A;  2HYV A;  2XO3 A;  1PBV A;  4KMU X;  4KN4 X;  4EVF A;  3ABO A;  4MDU A;  4D7Q A;  1SAV A;  1W7B A;  1YJ0 A;  1ALA A;  2ZOC A;  1R8S E;  1ANX A;  1YII A;  4EVH A;  1S9D E;  2II2 A;  1UPT B;  3SOH B;  2ZHJ A;  1G5N A;  1AVH A;  1QC7 A;  4JMO A;  1BCW A;  1N00 A;  4MDV A;  1HAK A;  4C0A A;  3AJC A;  1KU1 A;  1HVE A;  3ABQ A;  1YCN A;  1BC3 A;  1YGM A;  4JXH A;  2R0D A;  1N41 A;  1ANN A;  2HSN A;  3BRX A;  1XT0 B;  1W3W A;  4C7P A;  4L5M A;  1R4A E;  2HYU A;  1LKV X;  1HM6 A; 
#chains in the Genus database with same CATH homology
 1AEI A;  1MCX A;  2H0M A;  1N44 A;  1BCW A;  1A8A A;  1AOW A;  1BC0 A;  1N00 A;  2ZHI A;  1BO9 A;  1HVG A;  4MDV A;  2H0K A;  1N42 A;  2HYV A;  1HAK A;  2XO3 A;  1ANW A;  2H0L A;  4EVF A;  1HVE A;  1BCY A;  4MDU A;  1YCN A;  1HVF A;  1SAV A;  2IE6 A;  1DK5 A;  1W45 A;  1BC3 A;  1DM5 A;  1W7B A;  1YJ0 A;  1XJL A;  1AXN A;  1N41 A;  1ALA A;  1I4A A;  1ANN A;  2Q4C A;  2ZOC A;  1BC1 A;  1AVC A;  2IE7 A;  1A8B A;  2XO2 A;  1ANX A;  1YII A;  2HYW A;  2IIC A;  3BRX A;  1BCZ A;  1W3W A;  4X9P A;  4EVH A;  1M9I A;  4HRE A;  1AVR A;  1HVD A;  2RAN A;  2ZHJ A;  2II2 A;  1AII A;  2HYU A;  1HM6 A;  1G5N A;  1AVH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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