1HM6A

X-ray structure of full-length annexin 1
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
343
structure length
343
Chain Sequence
AMVSEFLKQAWFIDNEEQEYIKTVKGSKGGPGSAVSPYPTFNPSSDVEALHKAITVKGVDEATIIEILTKRTNAQRQQIKAAYLQEKGKPLDEALKKALTGHLEEVALALLKTPAQFDADELRAAMKGLGTDEDTLNEILASRTNREIREINRVYKEELKRDLAKDITSDTSGDYQKALLSLAKGDRSEDLAINDDLADTDARALYEAGERRKGTDLNVFITILTTRSYPHLRRVFQKYSKYSKHDMNKVLDLELKGDIENCLTVVVKCATSKPMFFAEKLHQAMKGIGTRHKTLIRIMVSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILVALCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of full-length annexin 1 and implications for membrane aggregation.
pubmed doi rcsb
molecule tags Metal, lipid binding protein
source organism Sus scrofa
molecule keywords ANNEXIN 1
total genus 136
structure length 343
sequence length 343
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1hm6A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1hm6A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1hm6A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1hm6A03
1N00A 1HVFA 2HYVA 2HYUA 1BCYA 1BC3A 1W3WA 1AXNA 2H0LA 1BC1A 2XO3A 1MCXA 1HVGA 2ZHIA 4X9PA 1BO9A 1BCWA 1YIIA 2IE7A 1AVRA 1ANNA 1XJLA 4HREA 2XO2A 1DK5A 1BCZA 1W7BA 2H0KA 2IE6A 1AVHA 1HM6A 1A8AA 1HAKA 1SAVA 1A8BA 2ZHJA 1YJ0A 1ANXA 1HVDA 1I4AA 4EVHA 1DM5A 1HVEA 1ANWA 1YCNA 3BRXA 1N42A 1W45A 4MDUA 2RANA 1AVCA 1ALAA 1BC0A 2II2A 2IICA 2ZOCA 1AEIA 1N41A 2H0MA 1G5NA 2Q4CA 2HYWA 4MDVA 1N44A 1M9IA 1AOWA 4EVFA 1AIIA
chains in the Genus database with same CATH superfamily
2HYUA 2K6XA 1BCYA 2R0DA 2ZHIA 3HJLA 1BCWA 1QC7A 1A8BA 1KU1A 1YJ0A 1HVDA 3ABSA 1YGMA 3BRXA 4C7PA 2RANA 4A4PA 1ALAA 1S9DE 4KMUX 1G5NA 1UPTB 2OY9A 1C1KA 2H0LA 1W3WA 4JK1X 1BC1A 3LTLA 1HVGA 4FHRB 3SWVA 4JMOA 2IE7A 1AVRA 1ANNA 1R8ME 4L5MA 1A8AA 1HAKA 3AO0A 4D7RA 1Q8DA 1ANXA 4D7QA 2QEZA 1ANWA 4MDUA 1BC0A 2II2A 3ANYA 1AEIA 1N41A 1XSZA 2H0MA 1N44A 1M9IA 1AOWA 4EVFA 1RE0B 4Z21A 1PBVA 3L8NA 1MCXA 1BO9A 4FQ0C 4HREA 1XJLA 2VXGA 3ABQA 2XO2A 1W7BA 2H0KA 1AVHA 1HM6A 1SAVA 2HSNA 1BC9A 4EVHA 1DM5A 1HVEA 3AJCA 1N42A 4OIYA 3USWA 2Q4CA 3TW5A 2HYWA 1N00A 1HVFA 2HYVA 4KN7X 1BC3A 1XT0B 1AXNA 2XO3A 4X9PA 2R09A 1YIIA 4C0AA 4Q2SA 1R8SE 1DK5A 4KN4X 1BCZA 4JMIA 2IE6A 1R4AE 4JXHA 2ZHJA 4JWLA 3ABRA 3USYA 1I4AA 1R8QE 3ABOA 1YCNA 1W45A 3SOHB 1AVCA 2IICA 2ZOCA 1LKVX 4MDVA 1AIIA
chains in the Genus database with same CATH topology
1N00A 1HVFA 2HYVA 2HYUA 1BCYA 1BC3A 1W3WA 1AXNA 2H0LA 1BC1A 2XO3A 1MCXA 1HVGA 2ZHIA 4X9PA 1BO9A 1BCWA 1YIIA 2IE7A 1AVRA 1ANNA 1XJLA 4HREA 2XO2A 1DK5A 1BCZA 1W7BA 2H0KA 2IE6A 1AVHA 1HM6A 1A8AA 1HAKA 1SAVA 1A8BA 2ZHJA 1YJ0A 1ANXA 1HVDA 1I4AA 4EVHA 1DM5A 1HVEA 1ANWA 1YCNA 3BRXA 1N42A 1W45A 4MDUA 2RANA 1AVCA 1ALAA 1BC0A 2II2A 2IICA 2ZOCA 1AEIA 1N41A 2H0MA 1G5NA 2Q4CA 2HYWA 4MDVA 1N44A 1M9IA 1AOWA 4EVFA 1AIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N00 A;  1HVF A;  2HYV A;  2HYU A;  1BCY A;  1BC3 A;  1W3W A;  1AXN A;  2H0L A;  1BC1 A;  2XO3 A;  1MCX A;  1HVG A;  2ZHI A;  4X9P A;  1BO9 A;  1BCW A;  1YII A;  2IE7 A;  1AVR A;  1ANN A;  1XJL A;  4HRE A;  2XO2 A;  1DK5 A;  1BCZ A;  1W7B A;  2H0K A;  2IE6 A;  1AVH A;  1HM6 A;  1A8A A;  1HAK A;  1SAV A;  1A8B A;  2ZHJ A;  1YJ0 A;  1ANX A;  1HVD A;  1I4A A;  4EVH A;  1DM5 A;  1HVE A;  1ANW A;  1YCN A;  3BRX A;  1N42 A;  1W45 A;  4MDU A;  2RAN A;  1AVC A;  1ALA A;  1BC0 A;  2II2 A;  2IIC A;  2ZOC A;  1AEI A;  1N41 A;  2H0M A;  1G5N A;  2Q4C A;  2HYW A;  4MDV A;  1N44 A;  1M9I A;  1AOW A;  4EVF A;  1AII A; 
#chains in the Genus database with same CATH topology
 2HYU A;  2K6X A;  1BCY A;  2R0D A;  2ZHI A;  3HJL A;  1BCW A;  1QC7 A;  1A8B A;  1KU1 A;  1YJ0 A;  1HVD A;  3ABS A;  1YGM A;  3BRX A;  4C7P A;  2RAN A;  4A4P A;  1ALA A;  1S9D E;  4KMU X;  1G5N A;  1UPT B;  2OY9 A;  1C1K A;  2H0L A;  1W3W A;  4JK1 X;  1BC1 A;  3LTL A;  1HVG A;  4FHR B;  3SWV A;  4JMO A;  2IE7 A;  1AVR A;  1ANN A;  1R8M E;  4L5M A;  1A8A A;  1HAK A;  3AO0 A;  4D7R A;  1Q8D A;  1ANX A;  4D7Q A;  2QEZ A;  1ANW A;  4MDU A;  1BC0 A;  2II2 A;  3ANY A;  1AEI A;  1N41 A;  1XSZ A;  2H0M A;  1N44 A;  1M9I A;  1AOW A;  4EVF A;  1RE0 B;  4Z21 A;  1PBV A;  3L8N A;  1MCX A;  1BO9 A;  4FQ0 C;  4HRE A;  1XJL A;  2VXG A;  3ABQ A;  2XO2 A;  1W7B A;  2H0K A;  1AVH A;  1HM6 A;  1SAV A;  2HSN A;  1BC9 A;  4EVH A;  1DM5 A;  1HVE A;  3AJC A;  1N42 A;  4OIY A;  3USW A;  2Q4C A;  3TW5 A;  2HYW A;  1N00 A;  1HVF A;  2HYV A;  4KN7 X;  1BC3 A;  1XT0 B;  1AXN A;  2XO3 A;  4X9P A;  2R09 A;  1YII A;  4C0A A;  4Q2S A;  1R8S E;  1DK5 A;  4KN4 X;  1BCZ A;  4JMI A;  2IE6 A;  1R4A E;  4JXH A;  2ZHJ A;  4JWL A;  3ABR A;  3USY A;  1I4A A;  1R8Q E;  3ABO A;  1YCN A;  1W45 A;  3SOH B;  1AVC A;  2IIC A;  2ZOC A;  1LKV X;  4MDV A;  1AII A; 
#chains in the Genus database with same CATH homology
 1N00 A;  1HVF A;  2HYV A;  2HYU A;  1BCY A;  1BC3 A;  1W3W A;  1AXN A;  2H0L A;  1BC1 A;  2XO3 A;  1MCX A;  1HVG A;  2ZHI A;  4X9P A;  1BO9 A;  1BCW A;  1YII A;  2IE7 A;  1AVR A;  1ANN A;  1XJL A;  4HRE A;  2XO2 A;  1DK5 A;  1BCZ A;  1W7B A;  2H0K A;  2IE6 A;  1AVH A;  1HM6 A;  1A8A A;  1HAK A;  1SAV A;  1A8B A;  2ZHJ A;  1YJ0 A;  1ANX A;  1HVD A;  1I4A A;  4EVH A;  1DM5 A;  1HVE A;  1ANW A;  1YCN A;  3BRX A;  1N42 A;  1W45 A;  4MDU A;  2RAN A;  1AVC A;  1ALA A;  1BC0 A;  2II2 A;  2IIC A;  2ZOC A;  1AEI A;  1N41 A;  2H0M A;  1G5N A;  2Q4C A;  2HYW A;  4MDV A;  1N44 A;  1M9I A;  1AOW A;  4EVF A;  1AII A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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