1I0EA

Crystal structure of creatine kinase from human muscle
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
374
structure length
365
Chain Sequence
NKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human muscle creatine kinase.
pubmed rcsb
molecule tags Transferase
molecule keywords CREATINE KINASE,M CHAIN
total genus 99
structure length 365
sequence length 374
chains with identical sequence B, C, D
ec nomenclature ec 2.7.3.2: Creatine kinase.
pdb deposition date 2001-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1i0eA01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1i0eA02
1RL9A 4GVYA 4BG4B 4GW0A 4LNNA 4BG4A 4S17A 4ACFA 3JU5A 1VRPA 4RF8A 4LNKA 1F52A 2J1QA 4S0RA 3ZXRA 2CRKA 2GLSA 4XYCA 1CRKA 1QH4A 4GVZA 1QK1A 1G0WA 5J99A 3NG0A 3JQ3A 1SD0A 4LNOA 1HTQA 4Q2RA 3L2EB 4LNFA 3L2EA 4RF9A 3L2DA 2WHIA 3ZXVA 3JPZA 2LGSA 4HPPA 3M10A 4BHLA 2WGSA 1HTOA 1BG0A 1P52A 3DRBA 4RF6A 4RF7A 2BVCA 1P50A 4AM1A 3B6RA 1U6RA 3DREA 1LGRA 4GW2A 1I0EA 5J9AA 4LNIA 1F1HA 1FPYA 1M15A 3JU6A 4Z9MA
chains in the Genus database with same CATH superfamily
4LNNA 4LNKA 3ZXRA 1QK1A 1G0WA 5J99A 3NG0A 2UU7A 3L2EA 4RF9A 2LGSA 3M10A 2WGSA 3LVWA 2OJWA 4RF7A 3LVVA 1P50A 3B6RA 3IG8A 3LN6A 4Z9MA 1RL9A 4BG4B 2D3AA 4BAXA 2J1QA 2D33A 2GWDA 1V4GA 4HPPA 1P52A 2BVCA 1LGRA 5J9AA 1F1HA 1FPYA 1M15A 4GVYA 4GW0A 4ACFA 3JU5A 1VRPA 4RF8A 3IG5A 1F52A 4S0RA 2CRKA 4XYCA 1QH4A 1R8GA 1TT4A 4LNOA 4Q2RA 3L2EB 4LNFA 3L2DA 1BG0A 4RF6A 1VA6A 4GW2A 4LNIA 2D3BA 3DRBA 3JU6A 3ZXVA 4BG4A 4S17A 2QC8A 2GLSA 1CRKA 2GWCA 4GVZA 3LN7A 3JQ3A 1SD0A 1HTQA 3NZTA 2WHIA 2D32A 3JPZA 4BHLA 4AM1A 3DREA 1U6RA 1I0EA 3FKYA 2D3CA 1HTOA
chains in the Genus database with same CATH topology
1RL9A 4GVYA 4BG4B 4GW0A 4LNNA 4BG4A 4S17A 4ACFA 3JU5A 1VRPA 4RF8A 4LNKA 1F52A 2J1QA 4S0RA 3ZXRA 2CRKA 2GLSA 4XYCA 1CRKA 1QH4A 4GVZA 1QK1A 1G0WA 5J99A 3NG0A 3JQ3A 1SD0A 4LNOA 1HTQA 4Q2RA 3L2EB 4LNFA 3L2EA 4RF9A 3L2DA 2WHIA 3ZXVA 3JPZA 2LGSA 4HPPA 3M10A 4BHLA 2WGSA 1HTOA 1BG0A 1P52A 3DRBA 4RF6A 4RF7A 2BVCA 1P50A 4AM1A 3B6RA 1U6RA 3DREA 1LGRA 4GW2A 1I0EA 5J9AA 4LNIA 1F1HA 1FPYA 1M15A 3JU6A 4Z9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RL9 A;  4GVY A;  4BG4 B;  4GW0 A;  4LNN A;  4BG4 A;  4S17 A;  4ACF A;  3JU5 A;  1VRP A;  4RF8 A;  4LNK A;  1F52 A;  2J1Q A;  4S0R A;  3ZXR A;  2CRK A;  2GLS A;  4XYC A;  1CRK A;  1QH4 A;  4GVZ A;  1QK1 A;  1G0W A;  5J99 A;  3NG0 A;  3JQ3 A;  1SD0 A;  4LNO A;  1HTQ A;  4Q2R A;  3L2E B;  4LNF A;  3L2E A;  4RF9 A;  3L2D A;  2WHI A;  3ZXV A;  3JPZ A;  2LGS A;  4HPP A;  3M10 A;  4BHL A;  2WGS A;  1HTO A;  1BG0 A;  1P52 A;  3DRB A;  4RF6 A;  4RF7 A;  2BVC A;  1P50 A;  4AM1 A;  3B6R A;  1U6R A;  3DRE A;  1LGR A;  4GW2 A;  1I0E A;  5J9A A;  4LNI A;  1F1H A;  1FPY A;  1M15 A;  3JU6 A;  4Z9M A; 
#chains in the Genus database with same CATH topology
 4LNN A;  4LNK A;  3ZXR A;  1QK1 A;  1G0W A;  5J99 A;  3NG0 A;  2UU7 A;  3L2E A;  4RF9 A;  2LGS A;  3M10 A;  2WGS A;  3LVW A;  2OJW A;  4RF7 A;  3LVV A;  1P50 A;  3B6R A;  3IG8 A;  3LN6 A;  4Z9M A;  1RL9 A;  4BG4 B;  2D3A A;  4BAX A;  2J1Q A;  2D33 A;  2GWD A;  1V4G A;  4HPP A;  1P52 A;  2BVC A;  1LGR A;  5J9A A;  1F1H A;  1FPY A;  1M15 A;  4GVY A;  4GW0 A;  4ACF A;  3JU5 A;  1VRP A;  4RF8 A;  3IG5 A;  1F52 A;  4S0R A;  2CRK A;  4XYC A;  1QH4 A;  1R8G A;  1TT4 A;  4LNO A;  4Q2R A;  3L2E B;  4LNF A;  3L2D A;  1BG0 A;  4RF6 A;  1VA6 A;  4GW2 A;  4LNI A;  2D3B A;  3DRB A;  3JU6 A;  3ZXV A;  4BG4 A;  4S17 A;  2QC8 A;  2GLS A;  1CRK A;  2GWC A;  4GVZ A;  3LN7 A;  3JQ3 A;  1SD0 A;  1HTQ A;  3NZT A;  2WHI A;  2D32 A;  3JPZ A;  4BHL A;  4AM1 A;  3DRE A;  1U6R A;  1I0E A;  3FKY A;  2D3C A;  1HTO A; 
#chains in the Genus database with same CATH homology
 1RL9 A;  4GVY A;  4BG4 B;  4GW0 A;  4LNN A;  4BG4 A;  4S17 A;  4ACF A;  3JU5 A;  1VRP A;  4RF8 A;  4LNK A;  1F52 A;  2J1Q A;  4S0R A;  3ZXR A;  2CRK A;  2GLS A;  4XYC A;  1CRK A;  1QH4 A;  4GVZ A;  1QK1 A;  1G0W A;  5J99 A;  3NG0 A;  3JQ3 A;  1SD0 A;  4LNO A;  1HTQ A;  4Q2R A;  3L2E B;  4LNF A;  3L2E A;  4RF9 A;  3L2D A;  2WHI A;  3ZXV A;  3JPZ A;  2LGS A;  4HPP A;  3M10 A;  4BHL A;  2WGS A;  1HTO A;  1BG0 A;  1P52 A;  3DRB A;  4RF6 A;  4RF7 A;  2BVC A;  1P50 A;  4AM1 A;  3B6R A;  1U6R A;  3DRE A;  1LGR A;  4GW2 A;  1I0E A;  5J9A A;  4LNI A;  1F1H A;  1FPY A;  1M15 A;  3JU6 A;  4Z9M A; 
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similar chains in the Genus database (?% sequence similarity)
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