2D33A

Crystal structure of gamma-glutamylcysteine synthetase complexed with aluminum fluoride
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
518
structure length
510
Chain Sequence
MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPSYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKSGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAISSSFLTSLPFEKTESGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of efficient coupling between peptide ligation and ATP hydrolysis by gamma-gluatamylcysteine synthetase
rcsb
source organism Escherichia coli
molecule tags Ligase
molecule keywords Glutamate--cysteine ligase
total genus 193
structure length 510
sequence length 518
chains with identical sequence B, C, D
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2005-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2d33A02
1R8GA 1VA6A 2D32A 3LN7A 3NZTA 1V4GA 3LN6A 2GWCA 2GWDA 2D33A 1TT4A
chains in the Genus database with same CATH superfamily
4AM1A 3JQ3A 3M10A 2D3AA 3NZTA 1BG0A 1FPYA 1V4GA 2OJWA 1SD0A 1VA6A 4LNFA 2J1QA 4XYCA 1P52A 4GVYA 3IG5A 1P50A 3FKYA 3NG0A 4RF7A 3ZXRA 1HTQA 1F1HA 3LN6A 4RF8A 4S17A 2CRKA 3B6RA 4LNOA 4ACFA 4BHLA 1G0WA 4LNKA 2WGSA 1TT4A 3JU6A 5J9AA 4BAXA 3LVWA 4S0RA 4GW0A 4BG4A 4BG4B 3IG8A 1QH4A 4Q2RA 3JU5A 3LVVA 4Z9MA 1CRKA 2D3BA 2D33A 4RF6A 3L2EA 2UU7A 2D3CA 3ZXVA 2GWCA 4GW2A 3L2DA 2QC8A 2BVCA 4LNNA 1VRPA 3L2EB 3LN7A 1F52A 4LNIA 2GLSA 4RF9A 1U6RA 1R8GA 4HPPA 2LGSA 3DREA 1M15A 1I0EA 2D32A 5J99A 1RL9A 2GWDA 2WHIA 3DRBA 3JPZA 1LGRA 1HTOA 1QK1A 4GVZA
chains in the Genus database with same CATH topology
2D3BA 3LN7A 2D33A 1R8GA 2UU7A 2D3CA 2D3AA 3LN6A 2GWCA 2D32A 3NZTA 1V4GA 2OJWA 2QC8A 2GWDA 1VA6A 1TT4A 4BAXA 3IG5A 3LVWA 3IG8A 3FKYA 3LVVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R8G A;  1VA6 A;  2D32 A;  3LN7 A;  3NZT A;  1V4G A;  3LN6 A;  2GWC A;  2GWD A;  2D33 A;  1TT4 A; 
#chains in the Genus database with same CATH topology
 4AM1 A;  3JQ3 A;  3M10 A;  2D3A A;  3NZT A;  1BG0 A;  1FPY A;  1V4G A;  2OJW A;  1SD0 A;  1VA6 A;  4LNF A;  2J1Q A;  4XYC A;  1P52 A;  4GVY A;  3IG5 A;  1P50 A;  3FKY A;  3NG0 A;  4RF7 A;  3ZXR A;  1HTQ A;  1F1H A;  3LN6 A;  4RF8 A;  4S17 A;  2CRK A;  3B6R A;  4LNO A;  4ACF A;  4BHL A;  1G0W A;  4LNK A;  2WGS A;  1TT4 A;  3JU6 A;  5J9A A;  4BAX A;  3LVW A;  4S0R A;  4GW0 A;  4BG4 A;  4BG4 B;  3IG8 A;  1QH4 A;  4Q2R A;  3JU5 A;  3LVV A;  4Z9M A;  1CRK A;  2D3B A;  2D33 A;  4RF6 A;  3L2E A;  2UU7 A;  2D3C A;  3ZXV A;  2GWC A;  4GW2 A;  3L2D A;  2QC8 A;  2BVC A;  4LNN A;  1VRP A;  3L2E B;  3LN7 A;  1F52 A;  4LNI A;  2GLS A;  4RF9 A;  1U6R A;  1R8G A;  4HPP A;  2LGS A;  3DRE A;  1M15 A;  1I0E A;  2D32 A;  5J99 A;  1RL9 A;  2GWD A;  2WHI A;  3DRB A;  3JPZ A;  1LGR A;  1HTO A;  1QK1 A;  4GVZ A; 
#chains in the Genus database with same CATH homology
 2D3B A;  3LN7 A;  2D33 A;  1R8G A;  2UU7 A;  2D3C A;  2D3A A;  3LN6 A;  2GWC A;  2D32 A;  3NZT A;  1V4G A;  2OJW A;  2QC8 A;  2GWD A;  1VA6 A;  1TT4 A;  4BAX A;  3IG5 A;  3LVW A;  3IG8 A;  3FKY A;  3LVV A; 
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similar chains in the pdb database (?% sequence similarity)

 
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