2D33A

Crystal structure of gamma-glutamylcysteine synthetase complexed with aluminum fluoride
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
518
structure length
510
Chain Sequence
b'MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPSYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKSGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAISSSFLTSLPFEKTESGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Glutamate--cysteine ligase
publication title Structural basis of efficient coupling between peptide ligation and ATP hydrolysis by gamma-gluatamylcysteine synthetase
rcsb
source organism Escherichia coli
molecule tags Ligase
total genus 193
structure length 510
sequence length 518
chains with identical sequence B, C, D
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2005-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2d33A02
1VA6A 3LN7A 2D32A 3LN6A 1TT4A 1V4GA 1R8GA 2D33A 2GWDA 3NZTA 2GWCA
chains in the Genus database with same CATH superfamily
1G0WA 2CRKA 1FPYA 5J99A 2WHIA 3JU6A 1U6RA 4LNFA 4GW0A 4LNIA 1BG0A 3IG5A 3ZXVA 1QH4A 4S0RA 1TT4A 4BG4B 4RF7A 1VRPA 1RL9A 1HTOA 1VA6A 3IG8A 2D32A 1LGRA 2D3CA 3JQ3A 4BG4A 2GWDA 2GLSA 2D3BA 3JU5A 2LGSA 1P50A 1CRKA 4HPPA 1F52A 2D3AA 4LNKA 1QK1A 4Z9MA 3L2DA 3NG0A 4BHLA 5J9AA 4LNOA 4LNNA 4RF9A 4XYCA 2QC8A 2BVCA 1P52A 3L2EA 3LVVA 2D33A 3NZTA 1F1HA 1I0EA 3LVWA 1SD0A 2J1QA 4RF6A 4S17A 3M10A 4BAXA 2UU7A 3LN7A 4RF8A 3DREA 1HTQA 1V4GA 2OJWA 4GVYA 4Q2RA 4AM1A 2GWCA 2WGSA 3LN6A 1R8GA 3JPZA 3DRBA 3L2EB 4ACFA 1M15A 4GW2A 3FKYA 3ZXRA 4GVZA 3B6RA
chains in the Genus database with same CATH topology
1VA6A 3IG8A 2D32A 2D3CA 4BAXA 2GWDA 2UU7A 3LN7A 2D3BA 1V4GA 2OJWA 2GWCA 3LN6A 3IG5A 1R8GA 2QC8A 3FKYA 1TT4A 3LVVA 2D33A 2D3AA 3NZTA 3LVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VA6 A;  3LN7 A;  2D32 A;  3LN6 A;  1TT4 A;  1V4G A;  1R8G A;  2D33 A;  2GWD A;  3NZT A;  2GWC A; 
#chains in the Genus database with same CATH topology
 1G0W A;  2CRK A;  1FPY A;  5J99 A;  2WHI A;  3JU6 A;  1U6R A;  4LNF A;  4GW0 A;  4LNI A;  1BG0 A;  3IG5 A;  3ZXV A;  1QH4 A;  4S0R A;  1TT4 A;  4BG4 B;  4RF7 A;  1VRP A;  1RL9 A;  1HTO A;  1VA6 A;  3IG8 A;  2D32 A;  1LGR A;  2D3C A;  3JQ3 A;  4BG4 A;  2GWD A;  2GLS A;  2D3B A;  3JU5 A;  2LGS A;  1P50 A;  1CRK A;  4HPP A;  1F52 A;  2D3A A;  4LNK A;  1QK1 A;  4Z9M A;  3L2D A;  3NG0 A;  4BHL A;  5J9A A;  4LNO A;  4LNN A;  4RF9 A;  4XYC A;  2QC8 A;  2BVC A;  1P52 A;  3L2E A;  3LVV A;  2D33 A;  3NZT A;  1F1H A;  1I0E A;  3LVW A;  1SD0 A;  2J1Q A;  4RF6 A;  4S17 A;  3M10 A;  4BAX A;  2UU7 A;  3LN7 A;  4RF8 A;  3DRE A;  1HTQ A;  1V4G A;  2OJW A;  4GVY A;  4Q2R A;  4AM1 A;  2GWC A;  2WGS A;  3LN6 A;  1R8G A;  3JPZ A;  3DRB A;  3L2E B;  4ACF A;  1M15 A;  4GW2 A;  3FKY A;  3ZXR A;  4GVZ A;  3B6R A; 
#chains in the Genus database with same CATH homology
 1VA6 A;  3IG8 A;  2D32 A;  2D3C A;  4BAX A;  2GWD A;  2UU7 A;  3LN7 A;  2D3B A;  1V4G A;  2OJW A;  2GWC A;  3LN6 A;  3IG5 A;  1R8G A;  2QC8 A;  3FKY A;  1TT4 A;  3LVV A;  2D33 A;  2D3A A;  3NZT A;  3LVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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