3NZTA

2.0 angstrom crystal structure of glutamate--cysteine ligase (gsha) ftom francisella tularensis in complex with amp
Total Genus 190
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
190
sequence length
500
structure length
498
Chain Sequence
YDFKKINNLRGIERETLRVTDCGNLATSNHPDGLGHKLTNNSITVDFSENLLELITKPHDSIDKAIGELYQLSAFTLDNMHSDEIILNTSMPLSANDNDIQEADFGSSNSGRMKRVYRKGLSARYGKIMQIISGIHYNFSFDKDLISNIATNKQVSISDIYFDVLNNYFEFMWLLPYLFGASPICAKTSVKNKPDYLSVLDDKFYVGEYATSLRMSDLGSPAQKDLAISYDNVKAYVKDLIQATDDTFADYKRIGLYNSQGQRIQLNDGILQIENEYYSAIRPKQIAKRGERPACALYNRGVEYVEVRVLDVDPFEPVGISKDTALFVEVMLMTCLDKDAKKYHKDIIKQAKQNLTAVAIQGRNPQLKLKKLDDDSEILLKDYALELFDEIEAVAKKMPKEYLDAVEIQKRKVLDISQTPSAKIIELARQHGYKKFILDISRRVSQQFRSYELPAAIVAKLKDQAGQSVAAEKELVANDKISLDEYINRYYKSSKGCC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title 2.0 Angstrom Crystal structure of Glutamate--Cysteine Ligase (gshA) ftom Francisella tularensis in Complex with AMP.
rcsb
source organism Francisella tularensis subsp. tularensis
molecule tags Ligase
molecule keywords Glutamate--cysteine ligase
total genus 190
structure length 498
sequence length 500
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 3nztA00
1V4GA 3LN7A 3NZTA 2GWCA 1VA6A 2GWDA 1TT4A 2D32A 2D33A 1R8GA 3LN6A
chains in the Genus database with same CATH superfamily
1HTOA 1HTQA 2BVCA 2CRKA 2D3CA 1VA6A 4RF9A 2WGSA 4GW0A 1CRKA 1QK1A 3FKYA 4GVZA 1FPYA 3JPZA 4BG4B 2D3AA 4RF8A 1F52A 2J1QA 3JQ3A 4RF6A 1RL9A 5J9AA 1P52A 2GWCA 3IG8A 4AM1A 2UU7A 3LN6A 4GVYA 1SD0A 3DRBA 2WHIA 1F1HA 3JU5A 3ZXRA 1M15A 1LGRA 1TT4A 2D3BA 4LNFA 1QH4A 4LNNA 4BAXA 2LGSA 3LVWA 1P50A 3DREA 4HPPA 3NZTA 1VRPA 2OJWA 3ZXVA 2QC8A 4BG4A 4ACFA 3LN7A 3NG0A 1V4GA 3L2EB 4Z9MA 4BHLA 3LVVA 4GW2A 4LNKA 2D32A 4Q2RA 1U6RA 3JU6A 3L2EA 2D33A 1G0WA 4LNIA 4S17A 5J99A 3IG5A 1R8GA 4LNOA 4S0RA 2GWDA 3B6RA 1BG0A 3M10A 1I0EA 2GLSA 4RF7A 4XYCA 3L2DA
chains in the Genus database with same CATH topology
3NZTA 2GWCA 3IG8A 2OJWA 2D33A 2QC8A 2UU7A 3LN6A 2D3CA 3LN7A 1VA6A 3IG5A 1R8GA 3FKYA 1V4GA 2GWDA 1TT4A 2D3BA 3LVVA 2D3AA 4BAXA 3LVWA 2D32A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V4G A;  3LN7 A;  3NZT A;  2GWC A;  1VA6 A;  2GWD A;  1TT4 A;  2D32 A;  2D33 A;  1R8G A;  3LN6 A; 
#chains in the Genus database with same CATH topology
 1HTO A;  1HTQ A;  2BVC A;  2CRK A;  2D3C A;  1VA6 A;  4RF9 A;  2WGS A;  4GW0 A;  1CRK A;  1QK1 A;  3FKY A;  4GVZ A;  1FPY A;  3JPZ A;  4BG4 B;  2D3A A;  4RF8 A;  1F52 A;  2J1Q A;  3JQ3 A;  4RF6 A;  1RL9 A;  5J9A A;  1P52 A;  2GWC A;  3IG8 A;  4AM1 A;  2UU7 A;  3LN6 A;  4GVY A;  1SD0 A;  3DRB A;  2WHI A;  1F1H A;  3JU5 A;  3ZXR A;  1M15 A;  1LGR A;  1TT4 A;  2D3B A;  4LNF A;  1QH4 A;  4LNN A;  4BAX A;  2LGS A;  3LVW A;  1P50 A;  3DRE A;  4HPP A;  3NZT A;  1VRP A;  2OJW A;  3ZXV A;  2QC8 A;  4BG4 A;  4ACF A;  3LN7 A;  3NG0 A;  1V4G A;  3L2E B;  4Z9M A;  4BHL A;  3LVV A;  4GW2 A;  4LNK A;  2D32 A;  4Q2R A;  1U6R A;  3JU6 A;  3L2E A;  2D33 A;  1G0W A;  4LNI A;  4S17 A;  5J99 A;  3IG5 A;  1R8G A;  4LNO A;  4S0R A;  2GWD A;  3B6R A;  1BG0 A;  3M10 A;  1I0E A;  2GLS A;  4RF7 A;  4XYC A;  3L2D A; 
#chains in the Genus database with same CATH homology
 3NZT A;  2GWC A;  3IG8 A;  2OJW A;  2D33 A;  2QC8 A;  2UU7 A;  3LN6 A;  2D3C A;  3LN7 A;  1VA6 A;  3IG5 A;  1R8G A;  3FKY A;  1V4G A;  2GWD A;  1TT4 A;  2D3B A;  3LVV A;  2D3A A;  4BAX A;  3LVW A;  2D32 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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