1SD0A

Structure of arginine kinase c271a mutant
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFAPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIRMEKAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants
pubmed doi rcsb
molecule tags Transferase
source organism Limulus polyphemus
molecule keywords Arginine kinase
total genus 125
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2004-02-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1sd0A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1sd0A02
3DREA 3L2DA 4AM1A 4GVYA 1BG0A 4GW0A 4ACFA 3ZXRA 4GVZA 4Z9MA 1I0EA 1RL9A 1VRPA 4RF6A 2BVCA 1FPYA 4RF9A 4Q2RA 3NG0A 4S0RA 3B6RA 4BHLA 4RF8A 3JPZA 1P50A 2GLSA 1U6RA 4BG4A 1LGRA 3DRBA 2J1QA 2LGSA 1P52A 4LNOA 4BG4B 4XYCA 1HTQA 4GW2A 3JU6A 4RF7A 1F1HA 1SD0A 2CRKA 4S17A 5J9AA 1QK1A 1G0WA 1F52A 1M15A 4HPPA 1CRKA 3L2EA 3ZXVA 1QH4A 3L2EB 4LNIA 5J99A 1HTOA 4LNFA 4LNNA 4LNKA 3JQ3A 3M10A 2WHIA 2WGSA 3JU5A
chains in the Genus database with same CATH superfamily
3DREA 1I0EA 2BVCA 3FKYA 2D33A 3B6RA 2GLSA 2LGSA 4LNOA 4GW2A 4S17A 1SD0A 2D3CA 1QK1A 2D3AA 1R8GA 4LNKA 2WHIA 3LVVA 2WGSA 3JU5A 3L2DA 1BG0A 4ACFA 4GVZA 4Z9MA 1VRPA 1TT4A 4S0RA 3IG8A 1F1HA 2OJWA 5J9AA 4BAXA 4HPPA 3ZXVA 3LN6A 4LNIA 4LNFA 3NZTA 3IG5A 3ZXRA 1RL9A 1V4GA 3NG0A 4RF8A 3JPZA 1U6RA 4BG4B 2D32A 4RF7A 1VA6A 1F52A 1M15A 2QC8A 1QH4A 3L2EB 4LNNA 3M10A 4Q2RA 4AM1A 4GVYA 4GW0A 4RF6A 2GWCA 1FPYA 4RF9A 4BHLA 2GWDA 1P50A 4BG4A 1LGRA 3DRBA 2J1QA 2UU7A 1P52A 4XYCA 1HTQA 3JU6A 2CRKA 1G0WA 1CRKA 2D3BA 3L2EA 5J99A 1HTOA 3LN7A 3JQ3A 3LVWA
chains in the Genus database with same CATH topology
3DREA 3L2DA 4AM1A 4GVYA 1BG0A 4GW0A 4ACFA 3ZXRA 4GVZA 4Z9MA 1I0EA 1RL9A 1VRPA 4RF6A 2BVCA 1FPYA 4RF9A 4Q2RA 3NG0A 4S0RA 3B6RA 4BHLA 4RF8A 3JPZA 1P50A 2GLSA 1U6RA 4BG4A 1LGRA 3DRBA 2J1QA 2LGSA 1P52A 4LNOA 4BG4B 4XYCA 1HTQA 4GW2A 3JU6A 4RF7A 1F1HA 1SD0A 2CRKA 4S17A 5J9AA 1QK1A 1G0WA 1F52A 1M15A 4HPPA 1CRKA 3L2EA 3ZXVA 1QH4A 3L2EB 4LNIA 5J99A 1HTOA 4LNFA 4LNNA 4LNKA 3JQ3A 3M10A 2WHIA 2WGSA 3JU5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DRE A;  3L2D A;  4AM1 A;  4GVY A;  1BG0 A;  4GW0 A;  4ACF A;  3ZXR A;  4GVZ A;  4Z9M A;  1I0E A;  1RL9 A;  1VRP A;  4RF6 A;  2BVC A;  1FPY A;  4RF9 A;  4Q2R A;  3NG0 A;  4S0R A;  3B6R A;  4BHL A;  4RF8 A;  3JPZ A;  1P50 A;  2GLS A;  1U6R A;  4BG4 A;  1LGR A;  3DRB A;  2J1Q A;  2LGS A;  1P52 A;  4LNO A;  4BG4 B;  4XYC A;  1HTQ A;  4GW2 A;  3JU6 A;  4RF7 A;  1F1H A;  1SD0 A;  2CRK A;  4S17 A;  5J9A A;  1QK1 A;  1G0W A;  1F52 A;  1M15 A;  4HPP A;  1CRK A;  3L2E A;  3ZXV A;  1QH4 A;  3L2E B;  4LNI A;  5J99 A;  1HTO A;  4LNF A;  4LNN A;  4LNK A;  3JQ3 A;  3M10 A;  2WHI A;  2WGS A;  3JU5 A; 
#chains in the Genus database with same CATH topology
 3DRE A;  1I0E A;  2BVC A;  3FKY A;  2D33 A;  3B6R A;  2GLS A;  2LGS A;  4LNO A;  4GW2 A;  4S17 A;  1SD0 A;  2D3C A;  1QK1 A;  2D3A A;  1R8G A;  4LNK A;  2WHI A;  3LVV A;  2WGS A;  3JU5 A;  3L2D A;  1BG0 A;  4ACF A;  4GVZ A;  4Z9M A;  1VRP A;  1TT4 A;  4S0R A;  3IG8 A;  1F1H A;  2OJW A;  5J9A A;  4BAX A;  4HPP A;  3ZXV A;  3LN6 A;  4LNI A;  4LNF A;  3NZT A;  3IG5 A;  3ZXR A;  1RL9 A;  1V4G A;  3NG0 A;  4RF8 A;  3JPZ A;  1U6R A;  4BG4 B;  2D32 A;  4RF7 A;  1VA6 A;  1F52 A;  1M15 A;  2QC8 A;  1QH4 A;  3L2E B;  4LNN A;  3M10 A;  4Q2R A;  4AM1 A;  4GVY A;  4GW0 A;  4RF6 A;  2GWC A;  1FPY A;  4RF9 A;  4BHL A;  2GWD A;  1P50 A;  4BG4 A;  1LGR A;  3DRB A;  2J1Q A;  2UU7 A;  1P52 A;  4XYC A;  1HTQ A;  3JU6 A;  2CRK A;  1G0W A;  1CRK A;  2D3B A;  3L2E A;  5J99 A;  1HTO A;  3LN7 A;  3JQ3 A;  3LVW A; 
#chains in the Genus database with same CATH homology
 3DRE A;  3L2D A;  4AM1 A;  4GVY A;  1BG0 A;  4GW0 A;  4ACF A;  3ZXR A;  4GVZ A;  4Z9M A;  1I0E A;  1RL9 A;  1VRP A;  4RF6 A;  2BVC A;  1FPY A;  4RF9 A;  4Q2R A;  3NG0 A;  4S0R A;  3B6R A;  4BHL A;  4RF8 A;  3JPZ A;  1P50 A;  2GLS A;  1U6R A;  4BG4 A;  1LGR A;  3DRB A;  2J1Q A;  2LGS A;  1P52 A;  4LNO A;  4BG4 B;  4XYC A;  1HTQ A;  4GW2 A;  3JU6 A;  4RF7 A;  1F1H A;  1SD0 A;  2CRK A;  4S17 A;  5J9A A;  1QK1 A;  1G0W A;  1F52 A;  1M15 A;  4HPP A;  1CRK A;  3L2E A;  3ZXV A;  1QH4 A;  3L2E B;  4LNI A;  5J99 A;  1HTO A;  4LNF A;  4LNN A;  4LNK A;  3JQ3 A;  3M10 A;  2WHI A;  2WGS A;  3JU5 A; 
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similar chains in the Genus database (?% sequence similarity)
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