4Q2RA

Structural proteomics from crude native rod outer segments
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
376
structure length
366
Chain Sequence
SHNLKLRFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGHPYIMTVGCVAGDEESYDVFKELFDPIIEDRHGGYKPTDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFPEVLKRLRLQKRGGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Proteomics From Crude Native Rod Outer Segments
rcsb
molecule tags Transferase
molecule keywords Creatine kinase B-type
total genus 128
structure length 366
sequence length 376
chains with identical sequence B
ec nomenclature ec 2.7.3.2: Creatine kinase.
pdb deposition date 2014-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 4q2rA01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 4q2rA02
4LNIA 3JPZA 4HPPA 5J9AA 4ACFA 1QH4A 1CRKA 1FPYA 4RF6A 1F1HA 3JU5A 1P50A 4GVYA 1LGRA 1F52A 3ZXRA 3DREA 4GW2A 3JQ3A 4BG4A 3L2EB 4RF9A 1QK1A 1G0WA 2CRKA 4Q2RA 1HTOA 2WHIA 2WGSA 4AM1A 4S17A 3NG0A 4LNKA 4RF7A 4BHLA 3ZXVA 2BVCA 1VRPA 1P52A 4GW0A 4Z9MA 3L2EA 1SD0A 3L2DA 4GVZA 1RL9A 2J1QA 2LGSA 4LNOA 3DRBA 1BG0A 3JU6A 3M10A 4LNNA 4S0RA 3B6RA 4RF8A 2GLSA 4LNFA 1M15A 1U6RA 1HTQA 4BG4B 5J99A 1I0EA 4XYCA
chains in the Genus database with same CATH superfamily
4LNIA 4HPPA 5J9AA 2UU7A 1CRKA 2OJWA 2D3CA 1HTOA 2WHIA 4LNKA 4BHLA 2GWDA 2BVCA 4LNOA 1BG0A 3ZXVA 3IG8A 1F52A 5J99A 4S0RA 1V4GA 3LVVA 1R8GA 1TT4A 3IG5A 2D3BA 3L2EB 1QK1A 2QC8A 4Q2RA 4S17A 1VRPA 3L2EA 2LGSA 3FKYA 3M10A 3B6RA 4RF8A 1I0EA 4XYCA 3JPZA 4ACFA 1QH4A 1FPYA 3LVWA 4RF6A 1F1HA 3JU5A 1P50A 4GW2A 3NZTA 3JQ3A 4RF9A 2CRKA 2WGSA 2D3AA 1P52A 4GW0A 3L2DA 1SD0A 4GVZA 2D33A 2J1QA 3DRBA 3LN6A 1HTQA 1U6RA 4BG4B 2D32A 3LN7A 1LGRA 3ZXRA 4GVYA 3DREA 4BG4A 1G0WA 4AM1A 2GWCA 3NG0A 4RF7A 4BAXA 1VA6A 4Z9MA 1RL9A 4LNNA 3JU6A 2GLSA 4LNFA 1M15A
chains in the Genus database with same CATH topology
4LNIA 3JPZA 4HPPA 5J9AA 4ACFA 1QH4A 1CRKA 1FPYA 4RF6A 1F1HA 3JU5A 1P50A 4GVYA 1LGRA 1F52A 3ZXRA 3DREA 4GW2A 3JQ3A 4BG4A 3L2EB 4RF9A 1QK1A 1G0WA 2CRKA 4Q2RA 1HTOA 2WHIA 2WGSA 4AM1A 4S17A 3NG0A 4LNKA 4RF7A 4BHLA 3ZXVA 2BVCA 1VRPA 1P52A 4GW0A 4Z9MA 3L2EA 1SD0A 3L2DA 4GVZA 1RL9A 2J1QA 2LGSA 4LNOA 3DRBA 1BG0A 3JU6A 3M10A 4LNNA 4S0RA 3B6RA 4RF8A 2GLSA 4LNFA 1M15A 1U6RA 1HTQA 4BG4B 5J99A 1I0EA 4XYCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LNI A;  3JPZ A;  4HPP A;  5J9A A;  4ACF A;  1QH4 A;  1CRK A;  1FPY A;  4RF6 A;  1F1H A;  3JU5 A;  1P50 A;  4GVY A;  1LGR A;  1F52 A;  3ZXR A;  3DRE A;  4GW2 A;  3JQ3 A;  4BG4 A;  3L2E B;  4RF9 A;  1QK1 A;  1G0W A;  2CRK A;  4Q2R A;  1HTO A;  2WHI A;  2WGS A;  4AM1 A;  4S17 A;  3NG0 A;  4LNK A;  4RF7 A;  4BHL A;  3ZXV A;  2BVC A;  1VRP A;  1P52 A;  4GW0 A;  4Z9M A;  3L2E A;  1SD0 A;  3L2D A;  4GVZ A;  1RL9 A;  2J1Q A;  2LGS A;  4LNO A;  3DRB A;  1BG0 A;  3JU6 A;  3M10 A;  4LNN A;  4S0R A;  3B6R A;  4RF8 A;  2GLS A;  4LNF A;  1M15 A;  1U6R A;  1HTQ A;  4BG4 B;  5J99 A;  1I0E A;  4XYC A; 
#chains in the Genus database with same CATH topology
 4LNI A;  4HPP A;  5J9A A;  2UU7 A;  1CRK A;  2OJW A;  2D3C A;  1HTO A;  2WHI A;  4LNK A;  4BHL A;  2GWD A;  2BVC A;  4LNO A;  1BG0 A;  3ZXV A;  3IG8 A;  1F52 A;  5J99 A;  4S0R A;  1V4G A;  3LVV A;  1R8G A;  1TT4 A;  3IG5 A;  2D3B A;  3L2E B;  1QK1 A;  2QC8 A;  4Q2R A;  4S17 A;  1VRP A;  3L2E A;  2LGS A;  3FKY A;  3M10 A;  3B6R A;  4RF8 A;  1I0E A;  4XYC A;  3JPZ A;  4ACF A;  1QH4 A;  1FPY A;  3LVW A;  4RF6 A;  1F1H A;  3JU5 A;  1P50 A;  4GW2 A;  3NZT A;  3JQ3 A;  4RF9 A;  2CRK A;  2WGS A;  2D3A A;  1P52 A;  4GW0 A;  3L2D A;  1SD0 A;  4GVZ A;  2D33 A;  2J1Q A;  3DRB A;  3LN6 A;  1HTQ A;  1U6R A;  4BG4 B;  2D32 A;  3LN7 A;  1LGR A;  3ZXR A;  4GVY A;  3DRE A;  4BG4 A;  1G0W A;  4AM1 A;  2GWC A;  3NG0 A;  4RF7 A;  4BAX A;  1VA6 A;  4Z9M A;  1RL9 A;  4LNN A;  3JU6 A;  2GLS A;  4LNF A;  1M15 A; 
#chains in the Genus database with same CATH homology
 4LNI A;  3JPZ A;  4HPP A;  5J9A A;  4ACF A;  1QH4 A;  1CRK A;  1FPY A;  4RF6 A;  1F1H A;  3JU5 A;  1P50 A;  4GVY A;  1LGR A;  1F52 A;  3ZXR A;  3DRE A;  4GW2 A;  3JQ3 A;  4BG4 A;  3L2E B;  4RF9 A;  1QK1 A;  1G0W A;  2CRK A;  4Q2R A;  1HTO A;  2WHI A;  2WGS A;  4AM1 A;  4S17 A;  3NG0 A;  4LNK A;  4RF7 A;  4BHL A;  3ZXV A;  2BVC A;  1VRP A;  1P52 A;  4GW0 A;  4Z9M A;  3L2E A;  1SD0 A;  3L2D A;  4GVZ A;  1RL9 A;  2J1Q A;  2LGS A;  4LNO A;  3DRB A;  1BG0 A;  3JU6 A;  3M10 A;  4LNN A;  4S0R A;  3B6R A;  4RF8 A;  2GLS A;  4LNF A;  1M15 A;  1U6R A;  1HTQ A;  4BG4 B;  5J99 A;  1I0E A;  4XYC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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