4GW2A

Crystal structure of arginine kinase in complex with l-ornithine, mgadp, and nitrate.
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginine kinase
publication title Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
pubmed doi rcsb
source organism Limulus polyphemus
molecule tags Transferase
total genus 128
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2012-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 4gw2A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 4gw2A02
4Z9MA 1I0EA 1HTOA 4S17A 4ACFA 3ZXRA 3L2DA 1M15A 2GLSA 4LNFA 4HPPA 1F1HA 1FPYA 1QK1A 1P50A 2J1QA 3L2EB 4Q2RA 4XYCA 3JQ3A 3ZXVA 4RF6A 1LGRA 1CRKA 1VRPA 1P52A 3M10A 1RL9A 4GW0A 4RF7A 3DRBA 3DREA 1QH4A 1G0WA 3L2EA 4GW2A 1HTQA 1BG0A 4RF8A 4LNNA 4GVYA 3B6RA 1SD0A 4LNKA 4LNOA 2CRKA 4BG4B 4BHLA 2WGSA 1F52A 2LGSA 3JU6A 3JU5A 1U6RA 4BG4A 5J9AA 4RF9A 4GVZA 4LNIA 5J99A 2WHIA 3NG0A 4AM1A 2BVCA 3JPZA 4S0RA
chains in the Genus database with same CATH superfamily
4Z9MA 1I0EA 4ACFA 1M15A 4HPPA 1P50A 2J1QA 3L2EB 4Q2RA 3IG8A 1CRKA 3L2EA 1BG0A 4RF8A 1SD0A 2D3BA 4LNKA 2CRKA 4LNOA 4BHLA 1F52A 1TT4A 4BG4A 1R8GA 4RF9A 2D33A 5J99A 2WHIA 4S0RA 1HTOA 2GWDA 1V4GA 4LNFA 1FPYA 4XYCA 4RF6A 1LGRA 1P52A 1RL9A 2D3AA 3DRBA 3DREA 1G0WA 4GW2A 4BG4B 3LVVA 5J9AA 4LNIA 3LN6A 3NG0A 1U6RA 2OJWA 3L2DA 3LVWA 1F1HA 3IG5A 2GWCA 3M10A 1HTQA 4LNNA 4BAXA 2QC8A 2WGSA 2LGSA 4GVZA 2BVCA 3JPZA 4S17A 3ZXRA 2GLSA 1QK1A 3ZXVA 3JQ3A 1VRPA 4GW0A 4RF7A 1QH4A 2D32A 4GVYA 3B6RA 3LN7A 2D3CA 3JU6A 3JU5A 2UU7A 3FKYA 3NZTA 4AM1A 1VA6A
chains in the Genus database with same CATH topology
4Z9MA 1I0EA 1HTOA 4S17A 4ACFA 3ZXRA 3L2DA 1M15A 2GLSA 4LNFA 4HPPA 1F1HA 1FPYA 1QK1A 1P50A 2J1QA 3L2EB 4Q2RA 4XYCA 3JQ3A 3ZXVA 4RF6A 1LGRA 1CRKA 1VRPA 1P52A 3M10A 1RL9A 4GW0A 4RF7A 3DRBA 3DREA 1QH4A 1G0WA 3L2EA 4GW2A 1HTQA 1BG0A 4RF8A 4LNNA 4GVYA 3B6RA 1SD0A 4LNKA 4LNOA 2CRKA 4BG4B 4BHLA 2WGSA 1F52A 2LGSA 3JU6A 3JU5A 1U6RA 4BG4A 5J9AA 4RF9A 4GVZA 4LNIA 5J99A 2WHIA 3NG0A 4AM1A 2BVCA 3JPZA 4S0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z9M A;  1I0E A;  1HTO A;  4S17 A;  4ACF A;  3ZXR A;  3L2D A;  1M15 A;  2GLS A;  4LNF A;  4HPP A;  1F1H A;  1FPY A;  1QK1 A;  1P50 A;  2J1Q A;  3L2E B;  4Q2R A;  4XYC A;  3JQ3 A;  3ZXV A;  4RF6 A;  1LGR A;  1CRK A;  1VRP A;  1P52 A;  3M10 A;  1RL9 A;  4GW0 A;  4RF7 A;  3DRB A;  3DRE A;  1QH4 A;  1G0W A;  3L2E A;  4GW2 A;  1HTQ A;  1BG0 A;  4RF8 A;  4LNN A;  4GVY A;  3B6R A;  1SD0 A;  4LNK A;  4LNO A;  2CRK A;  4BG4 B;  4BHL A;  2WGS A;  1F52 A;  2LGS A;  3JU6 A;  3JU5 A;  1U6R A;  4BG4 A;  5J9A A;  4RF9 A;  4GVZ A;  4LNI A;  5J99 A;  2WHI A;  3NG0 A;  4AM1 A;  2BVC A;  3JPZ A;  4S0R A; 
#chains in the Genus database with same CATH topology
 4Z9M A;  1I0E A;  4ACF A;  1M15 A;  4HPP A;  1P50 A;  2J1Q A;  3L2E B;  4Q2R A;  3IG8 A;  1CRK A;  3L2E A;  1BG0 A;  4RF8 A;  1SD0 A;  2D3B A;  4LNK A;  2CRK A;  4LNO A;  4BHL A;  1F52 A;  1TT4 A;  4BG4 A;  1R8G A;  4RF9 A;  2D33 A;  5J99 A;  2WHI A;  4S0R A;  1HTO A;  2GWD A;  1V4G A;  4LNF A;  1FPY A;  4XYC A;  4RF6 A;  1LGR A;  1P52 A;  1RL9 A;  2D3A A;  3DRB A;  3DRE A;  1G0W A;  4GW2 A;  4BG4 B;  3LVV A;  5J9A A;  4LNI A;  3LN6 A;  3NG0 A;  1U6R A;  2OJW A;  3L2D A;  3LVW A;  1F1H A;  3IG5 A;  2GWC A;  3M10 A;  1HTQ A;  4LNN A;  4BAX A;  2QC8 A;  2WGS A;  2LGS A;  4GVZ A;  2BVC A;  3JPZ A;  4S17 A;  3ZXR A;  2GLS A;  1QK1 A;  3ZXV A;  3JQ3 A;  1VRP A;  4GW0 A;  4RF7 A;  1QH4 A;  2D32 A;  4GVY A;  3B6R A;  3LN7 A;  2D3C A;  3JU6 A;  3JU5 A;  2UU7 A;  3FKY A;  3NZT A;  4AM1 A;  1VA6 A; 
#chains in the Genus database with same CATH homology
 4Z9M A;  1I0E A;  1HTO A;  4S17 A;  4ACF A;  3ZXR A;  3L2D A;  1M15 A;  2GLS A;  4LNF A;  4HPP A;  1F1H A;  1FPY A;  1QK1 A;  1P50 A;  2J1Q A;  3L2E B;  4Q2R A;  4XYC A;  3JQ3 A;  3ZXV A;  4RF6 A;  1LGR A;  1CRK A;  1VRP A;  1P52 A;  3M10 A;  1RL9 A;  4GW0 A;  4RF7 A;  3DRB A;  3DRE A;  1QH4 A;  1G0W A;  3L2E A;  4GW2 A;  1HTQ A;  1BG0 A;  4RF8 A;  4LNN A;  4GVY A;  3B6R A;  1SD0 A;  4LNK A;  4LNO A;  2CRK A;  4BG4 B;  4BHL A;  2WGS A;  1F52 A;  2LGS A;  3JU6 A;  3JU5 A;  1U6R A;  4BG4 A;  5J9A A;  4RF9 A;  4GVZ A;  4LNI A;  5J99 A;  2WHI A;  3NG0 A;  4AM1 A;  2BVC A;  3JPZ A;  4S0R A; 
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similar chains in the Genus database (?% sequence similarity)
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