4GW2A

Crystal structure of arginine kinase in complex with l-ornithine, mgadp, and nitrate.
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
pubmed doi rcsb
molecule tags Transferase
source organism Limulus polyphemus
molecule keywords Arginine kinase
total genus 128
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2012-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 4gw2A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 4gw2A02
3DREA 4Z9MA 1P52A 3NG0A 2J1QA 4AM1A 4RF7A 1G0WA 4XYCA 1SD0A 1QK1A 1F52A 4GVYA 1P50A 3L2EA 4Q2RA 4RF9A 4BG4A 4GW0A 4BHLA 2LGSA 1U6RA 4RF8A 1F1HA 5J99A 1LGRA 3ZXRA 5J9AA 1I0EA 2GLSA 1VRPA 1QH4A 3JQ3A 4LNFA 4GW2A 3DRBA 4LNKA 2CRKA 3L2DA 3ZXVA 1CRKA 2BVCA 3B6RA 4S17A 4S0RA 1HTQA 1BG0A 3JPZA 4LNOA 2WHIA 3JU6A 4GVZA 1HTOA 4ACFA 3JU5A 4LNNA 3L2EB 4RF6A 4BG4B 3M10A 4LNIA 1M15A 1FPYA 2WGSA 1RL9A 4HPPA
chains in the Genus database with same CATH superfamily
3NG0A 1P52A 1R8GA 4XYCA 1QK1A 1TT4A 4LNOA 1P50A 3L2EA 4Q2RA 4RF9A 2D32A 4RF8A 5J9AA 1I0EA 3L2DA 2D3CA 2GWDA 2QC8A 1BG0A 3L2EB 3LN7A 3DREA 4Z9MA 2J1QA 4GVYA 2LGSA 1F1HA 3IG8A 2CRKA 1CRKA 2BVCA 4S0RA 1VA6A 2D3AA 1V4GA 4GVZA 1HTOA 4ACFA 3JU5A 3LVVA 2WGSA 1RL9A 4HPPA 2GWCA 4AM1A 1G0WA 4BAXA 1F52A 3LN6A 4BG4A 4GW0A 2D33A 2GLSA 4LNFA 1QH4A 3JQ3A 4GW2A 4LNKA 4S17A 1HTQA 3NZTA 3JPZA 4LNNA 4BG4B 3M10A 4LNIA 1M15A 2UU7A 4RF7A 1SD0A 4BHLA 1U6RA 3ZXRA 5J99A 1LGRA 1VRPA 3DRBA 3IG5A 3ZXVA 3B6RA 2OJWA 2WHIA 3JU6A 2D3BA 3FKYA 4RF6A 3LVWA 1FPYA
chains in the Genus database with same CATH topology
3DREA 4Z9MA 1P52A 3NG0A 2J1QA 4AM1A 4RF7A 1G0WA 4XYCA 1SD0A 1QK1A 1F52A 4GVYA 1P50A 3L2EA 4Q2RA 4RF9A 4BG4A 4GW0A 4BHLA 2LGSA 1U6RA 4RF8A 1F1HA 5J99A 1LGRA 3ZXRA 5J9AA 1I0EA 2GLSA 1VRPA 1QH4A 3JQ3A 4LNFA 4GW2A 3DRBA 4LNKA 2CRKA 3L2DA 3ZXVA 1CRKA 2BVCA 3B6RA 4S17A 4S0RA 1HTQA 1BG0A 3JPZA 4LNOA 2WHIA 3JU6A 4GVZA 1HTOA 4ACFA 3JU5A 4LNNA 3L2EB 4RF6A 4BG4B 3M10A 4LNIA 1M15A 1FPYA 2WGSA 1RL9A 4HPPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DRE A;  4Z9M A;  1P52 A;  3NG0 A;  2J1Q A;  4AM1 A;  4RF7 A;  1G0W A;  4XYC A;  1SD0 A;  1QK1 A;  1F52 A;  4GVY A;  1P50 A;  3L2E A;  4Q2R A;  4RF9 A;  4BG4 A;  4GW0 A;  4BHL A;  2LGS A;  1U6R A;  4RF8 A;  1F1H A;  5J99 A;  1LGR A;  3ZXR A;  5J9A A;  1I0E A;  2GLS A;  1VRP A;  1QH4 A;  3JQ3 A;  4LNF A;  4GW2 A;  3DRB A;  4LNK A;  2CRK A;  3L2D A;  3ZXV A;  1CRK A;  2BVC A;  3B6R A;  4S17 A;  4S0R A;  1HTQ A;  1BG0 A;  3JPZ A;  4LNO A;  2WHI A;  3JU6 A;  4GVZ A;  1HTO A;  4ACF A;  3JU5 A;  4LNN A;  3L2E B;  4RF6 A;  4BG4 B;  3M10 A;  4LNI A;  1M15 A;  1FPY A;  2WGS A;  1RL9 A;  4HPP A; 
#chains in the Genus database with same CATH topology
 3NG0 A;  1P52 A;  1R8G A;  4XYC A;  1QK1 A;  1TT4 A;  4LNO A;  1P50 A;  3L2E A;  4Q2R A;  4RF9 A;  2D32 A;  4RF8 A;  5J9A A;  1I0E A;  3L2D A;  2D3C A;  2GWD A;  2QC8 A;  1BG0 A;  3L2E B;  3LN7 A;  3DRE A;  4Z9M A;  2J1Q A;  4GVY A;  2LGS A;  1F1H A;  3IG8 A;  2CRK A;  1CRK A;  2BVC A;  4S0R A;  1VA6 A;  2D3A A;  1V4G A;  4GVZ A;  1HTO A;  4ACF A;  3JU5 A;  3LVV A;  2WGS A;  1RL9 A;  4HPP A;  2GWC A;  4AM1 A;  1G0W A;  4BAX A;  1F52 A;  3LN6 A;  4BG4 A;  4GW0 A;  2D33 A;  2GLS A;  4LNF A;  1QH4 A;  3JQ3 A;  4GW2 A;  4LNK A;  4S17 A;  1HTQ A;  3NZT A;  3JPZ A;  4LNN A;  4BG4 B;  3M10 A;  4LNI A;  1M15 A;  2UU7 A;  4RF7 A;  1SD0 A;  4BHL A;  1U6R A;  3ZXR A;  5J99 A;  1LGR A;  1VRP A;  3DRB A;  3IG5 A;  3ZXV A;  3B6R A;  2OJW A;  2WHI A;  3JU6 A;  2D3B A;  3FKY A;  4RF6 A;  3LVW A;  1FPY A; 
#chains in the Genus database with same CATH homology
 3DRE A;  4Z9M A;  1P52 A;  3NG0 A;  2J1Q A;  4AM1 A;  4RF7 A;  1G0W A;  4XYC A;  1SD0 A;  1QK1 A;  1F52 A;  4GVY A;  1P50 A;  3L2E A;  4Q2R A;  4RF9 A;  4BG4 A;  4GW0 A;  4BHL A;  2LGS A;  1U6R A;  4RF8 A;  1F1H A;  5J99 A;  1LGR A;  3ZXR A;  5J9A A;  1I0E A;  2GLS A;  1VRP A;  1QH4 A;  3JQ3 A;  4LNF A;  4GW2 A;  3DRB A;  4LNK A;  2CRK A;  3L2D A;  3ZXV A;  1CRK A;  2BVC A;  3B6R A;  4S17 A;  4S0R A;  1HTQ A;  1BG0 A;  3JPZ A;  4LNO A;  2WHI A;  3JU6 A;  4GVZ A;  1HTO A;  4ACF A;  3JU5 A;  4LNN A;  3L2E B;  4RF6 A;  4BG4 B;  3M10 A;  4LNI A;  1M15 A;  1FPY A;  2WGS A;  1RL9 A;  4HPP A; 
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similar chains in the Genus database (?% sequence similarity)
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