1M15A

Transition state structure of arginine kinase
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refinement of the arginine kinase transition-state analogue complex at 1.2 A resolution: mechanistic insights.
pubmed doi rcsb
source organism Limulus polyphemus
molecule tags Transferase
molecule keywords arginine kinase
total genus 132
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2002-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1m15A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1m15A02
1SD0A 4LNOA 4ACFA 3JU6A 2LGSA 2WGSA 3DREA 1VRPA 1F1HA 4BG4A 1FPYA 5J99A 1HTOA 4AM1A 4XYCA 4BG4B 4HPPA 4LNNA 3ZXVA 1M15A 1QH4A 1QK1A 4RF6A 2GLSA 3JPZA 4BHLA 2CRKA 4GW2A 4LNKA 3ZXRA 3JU5A 3L2EA 4LNFA 4S17A 4RF8A 1BG0A 4GVYA 1LGRA 2BVCA 4GVZA 3DRBA 4RF7A 3L2DA 4Z9MA 4GW0A 3NG0A 1G0WA 4S0RA 3B6RA 3JQ3A 1P50A 1F52A 4Q2RA 4LNIA 1RL9A 1P52A 3L2EB 1U6RA 3M10A 4RF9A 5J9AA 1CRKA 1HTQA 2J1QA 2WHIA 1I0EA
chains in the Genus database with same CATH superfamily
1SD0A 4LNOA 2GWDA 4ACFA 1F1HA 4BG4A 1HTOA 2GWCA 3LVWA 2CRKA 4LNKA 3NG0A 3B6RA 1V4GA 1P52A 5J9AA 1R8GA 3IG5A 1VA6A 3DREA 4AM1A 4XYCA 4LNNA 3ZXVA 2QC8A 2GLSA 4BHLA 3ZXRA 3L2EA 4RF8A 1BG0A 1LGRA 2D3CA 4GVZA 3DRBA 3IG8A 4Z9MA 4GW0A 4S0RA 3JQ3A 3FKYA 3L2EB 1CRKA 2J1QA 1I0EA 3JU6A 4BAXA 1FPYA 5J99A 4BG4B 4HPPA 3LN7A 1M15A 4RF6A 3JPZA 4GW2A 4S17A 1TT4A 4RF7A 3L2DA 3LN6A 1G0WA 1P50A 1F52A 4Q2RA 2D32A 1HTQA 1U6RA 3M10A 2UU7A 2LGSA 2WGSA 3LVVA 1VRPA 2D3BA 1QH4A 1QK1A 3NZTA 3JU5A 4LNFA 4GVYA 2BVCA 2OJWA 4LNIA 1RL9A 4RF9A 2D33A 2D3AA 2WHIA
chains in the Genus database with same CATH topology
1SD0A 4LNOA 4ACFA 3JU6A 2LGSA 2WGSA 3DREA 1VRPA 1F1HA 4BG4A 1FPYA 5J99A 1HTOA 4AM1A 4XYCA 4BG4B 4HPPA 4LNNA 3ZXVA 1M15A 1QH4A 1QK1A 4RF6A 2GLSA 3JPZA 4BHLA 2CRKA 4GW2A 4LNKA 3ZXRA 3JU5A 3L2EA 4LNFA 4S17A 4RF8A 1BG0A 4GVYA 1LGRA 2BVCA 4GVZA 3DRBA 4RF7A 3L2DA 4Z9MA 4GW0A 3NG0A 1G0WA 4S0RA 3B6RA 3JQ3A 1P50A 1F52A 4Q2RA 4LNIA 1RL9A 1P52A 3L2EB 1U6RA 3M10A 4RF9A 5J9AA 1CRKA 1HTQA 2J1QA 2WHIA 1I0EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SD0 A;  4LNO A;  4ACF A;  3JU6 A;  2LGS A;  2WGS A;  3DRE A;  1VRP A;  1F1H A;  4BG4 A;  1FPY A;  5J99 A;  1HTO A;  4AM1 A;  4XYC A;  4BG4 B;  4HPP A;  4LNN A;  3ZXV A;  1M15 A;  1QH4 A;  1QK1 A;  4RF6 A;  2GLS A;  3JPZ A;  4BHL A;  2CRK A;  4GW2 A;  4LNK A;  3ZXR A;  3JU5 A;  3L2E A;  4LNF A;  4S17 A;  4RF8 A;  1BG0 A;  4GVY A;  1LGR A;  2BVC A;  4GVZ A;  3DRB A;  4RF7 A;  3L2D A;  4Z9M A;  4GW0 A;  3NG0 A;  1G0W A;  4S0R A;  3B6R A;  3JQ3 A;  1P50 A;  1F52 A;  4Q2R A;  4LNI A;  1RL9 A;  1P52 A;  3L2E B;  1U6R A;  3M10 A;  4RF9 A;  5J9A A;  1CRK A;  1HTQ A;  2J1Q A;  2WHI A;  1I0E A; 
#chains in the Genus database with same CATH topology
 1SD0 A;  4LNO A;  2GWD A;  4ACF A;  1F1H A;  4BG4 A;  1HTO A;  2GWC A;  3LVW A;  2CRK A;  4LNK A;  3NG0 A;  3B6R A;  1V4G A;  1P52 A;  5J9A A;  1R8G A;  3IG5 A;  1VA6 A;  3DRE A;  4AM1 A;  4XYC A;  4LNN A;  3ZXV A;  2QC8 A;  2GLS A;  4BHL A;  3ZXR A;  3L2E A;  4RF8 A;  1BG0 A;  1LGR A;  2D3C A;  4GVZ A;  3DRB A;  3IG8 A;  4Z9M A;  4GW0 A;  4S0R A;  3JQ3 A;  3FKY A;  3L2E B;  1CRK A;  2J1Q A;  1I0E A;  3JU6 A;  4BAX A;  1FPY A;  5J99 A;  4BG4 B;  4HPP A;  3LN7 A;  1M15 A;  4RF6 A;  3JPZ A;  4GW2 A;  4S17 A;  1TT4 A;  4RF7 A;  3L2D A;  3LN6 A;  1G0W A;  1P50 A;  1F52 A;  4Q2R A;  2D32 A;  1HTQ A;  1U6R A;  3M10 A;  2UU7 A;  2LGS A;  2WGS A;  3LVV A;  1VRP A;  2D3B A;  1QH4 A;  1QK1 A;  3NZT A;  3JU5 A;  4LNF A;  4GVY A;  2BVC A;  2OJW A;  4LNI A;  1RL9 A;  4RF9 A;  2D33 A;  2D3A A;  2WHI A; 
#chains in the Genus database with same CATH homology
 1SD0 A;  4LNO A;  4ACF A;  3JU6 A;  2LGS A;  2WGS A;  3DRE A;  1VRP A;  1F1H A;  4BG4 A;  1FPY A;  5J99 A;  1HTO A;  4AM1 A;  4XYC A;  4BG4 B;  4HPP A;  4LNN A;  3ZXV A;  1M15 A;  1QH4 A;  1QK1 A;  4RF6 A;  2GLS A;  3JPZ A;  4BHL A;  2CRK A;  4GW2 A;  4LNK A;  3ZXR A;  3JU5 A;  3L2E A;  4LNF A;  4S17 A;  4RF8 A;  1BG0 A;  4GVY A;  1LGR A;  2BVC A;  4GVZ A;  3DRB A;  4RF7 A;  3L2D A;  4Z9M A;  4GW0 A;  3NG0 A;  1G0W A;  4S0R A;  3B6R A;  3JQ3 A;  1P50 A;  1F52 A;  4Q2R A;  4LNI A;  1RL9 A;  1P52 A;  3L2E B;  1U6R A;  3M10 A;  4RF9 A;  5J9A A;  1CRK A;  1HTQ A;  2J1Q A;  2WHI A;  1I0E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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