2D32A

Crystal structure of michaelis complex of gamma-glutamylcysteine synthetase
Total Genus 188
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
188
sequence length
518
structure length
510
Chain Sequence
MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPSYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKSGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAISSSFLTSLPFEKTESGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of efficient coupling peptide ligation and ATP hydrolysis by gamma-gluatamylcysteine synthetase
rcsb
source organism Escherichia coli
molecule tags Ligase
molecule keywords Glutamate--cysteine ligase
total genus 188
structure length 510
sequence length 518
chains with identical sequence B, C, D
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2005-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2d32A02
1TT4A 1V4GA 1VA6A 2D33A 3LN6A 2GWCA 2GWDA 3LN7A 3NZTA 1R8GA 2D32A
chains in the Genus database with same CATH superfamily
1QK1A 3LN6A 4AM1A 1F1HA 4ACFA 3IG5A 1LGRA 4GVZA 3IG8A 4LNOA 3LVWA 3M10A 1HTQA 3DRBA 2J1QA 4RF6A 3JU6A 4BAXA 3NG0A 1FPYA 1HTOA 2GLSA 3L2DA 3JPZA 1G0WA 1QH4A 2QC8A 2D3BA 4RF8A 2UU7A 4BG4B 2D3CA 5J99A 3NZTA 3L2EA 2WGSA 5J9AA 3JU5A 2D3AA 4LNFA 1VRPA 3L2EB 4RF7A 1U6RA 2CRKA 1M15A 4Z9MA 3DREA 4BHLA 4LNKA 4S17A 1SD0A 4XYCA 4Q2RA 3ZXRA 2BVCA 1P50A 1V4GA 1VA6A 2D33A 2GWDA 1F52A 4BG4A 2GWCA 1I0EA 1TT4A 3B6RA 3JQ3A 3LVVA 1RL9A 3LN7A 4RF9A 3FKYA 1BG0A 2D32A 4GVYA 4LNIA 1P52A 2OJWA 4GW0A 1R8GA 4LNNA 3ZXVA 4HPPA 4S0RA 2LGSA 2WHIA 1CRKA 4GW2A
chains in the Genus database with same CATH topology
1TT4A 4BAXA 3LVVA 3LN6A 3LN7A 3FKYA 2D32A 2QC8A 2OJWA 3IG5A 2D3BA 1R8GA 2UU7A 1V4GA 1VA6A 2D33A 3IG8A 2D3CA 2GWDA 3NZTA 3LVWA 2GWCA 2D3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TT4 A;  1V4G A;  1VA6 A;  2D33 A;  3LN6 A;  2GWC A;  2GWD A;  3LN7 A;  3NZT A;  1R8G A;  2D32 A; 
#chains in the Genus database with same CATH topology
 1QK1 A;  3LN6 A;  4AM1 A;  1F1H A;  4ACF A;  3IG5 A;  1LGR A;  4GVZ A;  3IG8 A;  4LNO A;  3LVW A;  3M10 A;  1HTQ A;  3DRB A;  2J1Q A;  4RF6 A;  3JU6 A;  4BAX A;  3NG0 A;  1FPY A;  1HTO A;  2GLS A;  3L2D A;  3JPZ A;  1G0W A;  1QH4 A;  2QC8 A;  2D3B A;  4RF8 A;  2UU7 A;  4BG4 B;  2D3C A;  5J99 A;  3NZT A;  3L2E A;  2WGS A;  5J9A A;  3JU5 A;  2D3A A;  4LNF A;  1VRP A;  3L2E B;  4RF7 A;  1U6R A;  2CRK A;  1M15 A;  4Z9M A;  3DRE A;  4BHL A;  4LNK A;  4S17 A;  1SD0 A;  4XYC A;  4Q2R A;  3ZXR A;  2BVC A;  1P50 A;  1V4G A;  1VA6 A;  2D33 A;  2GWD A;  1F52 A;  4BG4 A;  2GWC A;  1I0E A;  1TT4 A;  3B6R A;  3JQ3 A;  3LVV A;  1RL9 A;  3LN7 A;  4RF9 A;  3FKY A;  1BG0 A;  2D32 A;  4GVY A;  4LNI A;  1P52 A;  2OJW A;  4GW0 A;  1R8G A;  4LNN A;  3ZXV A;  4HPP A;  4S0R A;  2LGS A;  2WHI A;  1CRK A;  4GW2 A; 
#chains in the Genus database with same CATH homology
 1TT4 A;  4BAX A;  3LVV A;  3LN6 A;  3LN7 A;  3FKY A;  2D32 A;  2QC8 A;  2OJW A;  3IG5 A;  2D3B A;  1R8G A;  2UU7 A;  1V4G A;  1VA6 A;  2D33 A;  3IG8 A;  2D3C A;  2GWD A;  3NZT A;  3LVW A;  2GWC A;  2D3A A; 
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similar chains in the pdb database (?% sequence similarity)

 
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