2D32A

Crystal structure of michaelis complex of gamma-glutamylcysteine synthetase
Total Genus 188
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
188
sequence length
518
structure length
510
Chain Sequence
b'MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPSYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKSGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAISSSFLTSLPFEKTESGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Glutamate--cysteine ligase
publication title Structural basis of efficient coupling peptide ligation and ATP hydrolysis by gamma-gluatamylcysteine synthetase
rcsb
source organism Escherichia coli
molecule tags Ligase
total genus 188
structure length 510
sequence length 518
chains with identical sequence B, C, D
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2005-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2d32A02
2GWDA 2D32A 2GWCA 3NZTA 1VA6A 1TT4A 2D33A 1R8GA 1V4GA 3LN6A 3LN7A
chains in the Genus database with same CATH superfamily
3IG5A 4BAXA 1VA6A 4RF9A 2GWDA 3ZXVA 1F1HA 1P50A 3NG0A 3JU6A 4Q2RA 5J9AA 1G0WA 4GVZA 3LVVA 3JU5A 4RF7A 4LNIA 3JPZA 1QK1A 3L2EB 1P52A 4BG4A 3LN7A 1CRKA 2D3BA 4LNNA 2UU7A 1R8GA 2J1QA 1HTQA 4S17A 3IG8A 3LVWA 2GLSA 4RF8A 4BG4B 1VRPA 1QH4A 2QC8A 4BHLA 3L2DA 4LNFA 1SD0A 5J99A 3FKYA 1I0EA 2D3AA 4AM1A 2GWCA 1HTOA 3M10A 3B6RA 3NZTA 2WGSA 4ACFA 3DREA 4GW2A 3LN6A 1LGRA 4LNOA 2D3CA 3ZXRA 4XYCA 2BVCA 2D32A 1FPYA 3L2EA 4RF6A 1F52A 2WHIA 3JQ3A 1TT4A 2OJWA 4GVYA 4HPPA 4LNKA 4Z9MA 1U6RA 3DRBA 1BG0A 4GW0A 2D33A 1RL9A 1V4GA 1M15A 2CRKA 2LGSA 4S0RA
chains in the Genus database with same CATH topology
2D32A 1TT4A 3IG5A 2OJWA 3LN7A 2QC8A 4BAXA 1VA6A 2D3BA 3FKYA 2D3AA 2GWDA 2GWCA 3NZTA 2D33A 2UU7A 1R8GA 1V4GA 3LN6A 3LVVA 3IG8A 2D3CA 3LVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GWD A;  2D32 A;  2GWC A;  3NZT A;  1VA6 A;  1TT4 A;  2D33 A;  1R8G A;  1V4G A;  3LN6 A;  3LN7 A; 
#chains in the Genus database with same CATH topology
 3IG5 A;  4BAX A;  1VA6 A;  4RF9 A;  2GWD A;  3ZXV A;  1F1H A;  1P50 A;  3NG0 A;  3JU6 A;  4Q2R A;  5J9A A;  1G0W A;  4GVZ A;  3LVV A;  3JU5 A;  4RF7 A;  4LNI A;  3JPZ A;  1QK1 A;  3L2E B;  1P52 A;  4BG4 A;  3LN7 A;  1CRK A;  2D3B A;  4LNN A;  2UU7 A;  1R8G A;  2J1Q A;  1HTQ A;  4S17 A;  3IG8 A;  3LVW A;  2GLS A;  4RF8 A;  4BG4 B;  1VRP A;  1QH4 A;  2QC8 A;  4BHL A;  3L2D A;  4LNF A;  1SD0 A;  5J99 A;  3FKY A;  1I0E A;  2D3A A;  4AM1 A;  2GWC A;  1HTO A;  3M10 A;  3B6R A;  3NZT A;  2WGS A;  4ACF A;  3DRE A;  4GW2 A;  3LN6 A;  1LGR A;  4LNO A;  2D3C A;  3ZXR A;  4XYC A;  2BVC A;  2D32 A;  1FPY A;  3L2E A;  4RF6 A;  1F52 A;  2WHI A;  3JQ3 A;  1TT4 A;  2OJW A;  4GVY A;  4HPP A;  4LNK A;  4Z9M A;  1U6R A;  3DRB A;  1BG0 A;  4GW0 A;  2D33 A;  1RL9 A;  1V4G A;  1M15 A;  2CRK A;  2LGS A;  4S0R A; 
#chains in the Genus database with same CATH homology
 2D32 A;  1TT4 A;  3IG5 A;  2OJW A;  3LN7 A;  2QC8 A;  4BAX A;  1VA6 A;  2D3B A;  3FKY A;  2D3A A;  2GWD A;  2GWC A;  3NZT A;  2D33 A;  2UU7 A;  1R8G A;  1V4G A;  3LN6 A;  3LVV A;  3IG8 A;  2D3C A;  3LVW A; 
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similar chains in the pdb database (?% sequence similarity)

 
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