2GWCA

Crystal structure of plant glutamate cysteine ligase in complex with a transition state analogue
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
438
structure length
438
Chain Sequence
ATEPLTREDLIAYLASGCKSKEKWRIGTEHEKFGFEVNTLRPMKYDQIAELLNSIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGMGFQPKWRREDIPTMPKGRYDIMRNYMPKVGSLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYALDVPMYFAYRNGKYVDCTGMTFRQFLAGKLPCLPGELPTYNDWENHLTTIFPEVRLKRYMEMRGADGGPWRRLCALPAFWVGLLYDEDVLQSVLDLTADWTPAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEVGFLNAVTEVVRTGVTPAENLLEMYNGEWGQSVDPVFQELLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Glutamate cysteine ligase
publication title Structural basis for the redox control of plant glutamate cysteine ligase.
pubmed doi rcsb
source organism Brassica juncea
molecule tags Ligase
total genus 139
structure length 438
sequence length 438
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04107 GCS2 Glutamate-cysteine ligase family 2(GCS2)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2gwcA00
2GWDA 1VA6A 2D33A 3LN7A 3NZTA 2GWCA 1TT4A 1V4GA 3LN6A 2D32A 1R8GA
chains in the Genus database with same CATH superfamily
4BHLA 2GWDA 1G0WA 1U6RA 1CRKA 4LNFA 2BVCA 2LGSA 3JU6A 3JPZA 4GVYA 2D33A 1M15A 4HPPA 1SD0A 3DREA 5J9AA 1QK1A 1VRPA 2UU7A 4AM1A 4RF6A 1P50A 3B6RA 3JU5A 1HTQA 1F1HA 4GVZA 3ZXVA 1TT4A 1V4GA 4Q2RA 3L2EA 1I0EA 3JQ3A 1HTOA 4BG4B 1VA6A 1BG0A 5J99A 4ACFA 3ZXRA 4XYCA 3IG8A 3M10A 2D3BA 3FKYA 4LNIA 2D32A 1FPYA 2J1QA 4RF9A 4LNKA 4GW0A 4Z9MA 2D3AA 2GWCA 2WGSA 4RF8A 4BAXA 3LN7A 3LVVA 3DRBA 4S17A 3L2EB 3LN6A 4LNNA 3L2DA 1LGRA 3NG0A 2OJWA 1QH4A 2WHIA 4GW2A 2GLSA 2QC8A 4LNOA 4RF7A 1R8GA 4S0RA 4BG4A 2CRKA 3LVWA 1P52A 3NZTA 1F52A 1RL9A 2D3CA 3IG5A
chains in the Genus database with same CATH topology
2GWDA 2OJWA 3FKYA 1TT4A 1V4GA 2D32A 1VA6A 2QC8A 1R8GA 2D33A 2D3AA 2GWCA 3LVWA 4BAXA 3LN7A 3LVVA 3IG8A 2D3BA 3NZTA 2UU7A 2D3CA 3LN6A 3IG5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GWD A;  1VA6 A;  2D33 A;  3LN7 A;  3NZT A;  2GWC A;  1TT4 A;  1V4G A;  3LN6 A;  2D32 A;  1R8G A; 
#chains in the Genus database with same CATH topology
 4BHL A;  2GWD A;  1G0W A;  1U6R A;  1CRK A;  4LNF A;  2BVC A;  2LGS A;  3JU6 A;  3JPZ A;  4GVY A;  2D33 A;  1M15 A;  4HPP A;  1SD0 A;  3DRE A;  5J9A A;  1QK1 A;  1VRP A;  2UU7 A;  4AM1 A;  4RF6 A;  1P50 A;  3B6R A;  3JU5 A;  1HTQ A;  1F1H A;  4GVZ A;  3ZXV A;  1TT4 A;  1V4G A;  4Q2R A;  3L2E A;  1I0E A;  3JQ3 A;  1HTO A;  4BG4 B;  1VA6 A;  1BG0 A;  5J99 A;  4ACF A;  3ZXR A;  4XYC A;  3IG8 A;  3M10 A;  2D3B A;  3FKY A;  4LNI A;  2D32 A;  1FPY A;  2J1Q A;  4RF9 A;  4LNK A;  4GW0 A;  4Z9M A;  2D3A A;  2GWC A;  2WGS A;  4RF8 A;  4BAX A;  3LN7 A;  3LVV A;  3DRB A;  4S17 A;  3L2E B;  3LN6 A;  4LNN A;  3L2D A;  1LGR A;  3NG0 A;  2OJW A;  1QH4 A;  2WHI A;  4GW2 A;  2GLS A;  2QC8 A;  4LNO A;  4RF7 A;  1R8G A;  4S0R A;  4BG4 A;  2CRK A;  3LVW A;  1P52 A;  3NZT A;  1F52 A;  1RL9 A;  2D3C A;  3IG5 A; 
#chains in the Genus database with same CATH homology
 2GWD A;  2OJW A;  3FKY A;  1TT4 A;  1V4G A;  2D32 A;  1VA6 A;  2QC8 A;  1R8G A;  2D33 A;  2D3A A;  2GWC A;  3LVW A;  4BAX A;  3LN7 A;  3LVV A;  3IG8 A;  2D3B A;  3NZT A;  2UU7 A;  2D3C A;  3LN6 A;  3IG5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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