2GWCA

Crystal structure of plant glutamate cysteine ligase in complex with a transition state analogue
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
438
structure length
438
Chain Sequence
ATEPLTREDLIAYLASGCKSKEKWRIGTEHEKFGFEVNTLRPMKYDQIAELLNSIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGMGFQPKWRREDIPTMPKGRYDIMRNYMPKVGSLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYALDVPMYFAYRNGKYVDCTGMTFRQFLAGKLPCLPGELPTYNDWENHLTTIFPEVRLKRYMEMRGADGGPWRRLCALPAFWVGLLYDEDVLQSVLDLTADWTPAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEVGFLNAVTEVVRTGVTPAENLLEMYNGEWGQSVDPVFQELLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the redox control of plant glutamate cysteine ligase.
pubmed doi rcsb
source organism Brassica juncea
molecule tags Ligase
molecule keywords Glutamate cysteine ligase
total genus 139
structure length 438
sequence length 438
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04107 GCS2 Glutamate-cysteine ligase family 2(GCS2)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2gwcA00
3NZTA 2D32A 1VA6A 2GWCA 3LN6A 1V4GA 3LN7A 1R8GA 2GWDA 1TT4A 2D33A
chains in the Genus database with same CATH superfamily
4BAXA 3L2DA 2WHIA 1TT4A 1F52A 1M15A 2BVCA 2CRKA 3JPZA 1QK1A 4RF7A 1P52A 1BG0A 1CRKA 2GWDA 2OJWA 4LNOA 1HTQA 1RL9A 2UU7A 4RF9A 3L2EA 2D33A 2D3BA 1P50A 4LNKA 4XYCA 4GW0A 1SD0A 4LNIA 4GVZA 2J1QA 3IG5A 1I0EA 3JQ3A 3NZTA 4GW2A 1VA6A 4AM1A 4HPPA 3ZXVA 1QH4A 2D3CA 1F1HA 2D3AA 4BG4B 1V4GA 1U6RA 3ZXRA 3LVWA 4LNFA 2LGSA 4BG4A 4BHLA 3B6RA 3L2EB 4Z9MA 3NG0A 3LN7A 4S0RA 4GVYA 1G0WA 1VRPA 2QC8A 2GLSA 4RF6A 3M10A 2GWCA 4LNNA 5J9AA 1HTOA 3IG8A 3DREA 2WGSA 3LVVA 5J99A 3LN6A 1R8GA 3DRBA 4ACFA 2D32A 1FPYA 4S17A 3FKYA 1LGRA 4Q2RA 3JU5A 4RF8A 3JU6A
chains in the Genus database with same CATH topology
4BAXA 2GWCA 1V4GA 2D3BA 3LVWA 3IG8A 1TT4A 3LVVA 3LN6A 3LN7A 1R8GA 3IG5A 3NZTA 2D32A 1VA6A 2D3CA 2OJWA 2GWDA 3FKYA 2QC8A 2D3AA 2UU7A 2D33A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NZT A;  2D32 A;  1VA6 A;  2GWC A;  3LN6 A;  1V4G A;  3LN7 A;  1R8G A;  2GWD A;  1TT4 A;  2D33 A; 
#chains in the Genus database with same CATH topology
 4BAX A;  3L2D A;  2WHI A;  1TT4 A;  1F52 A;  1M15 A;  2BVC A;  2CRK A;  3JPZ A;  1QK1 A;  4RF7 A;  1P52 A;  1BG0 A;  1CRK A;  2GWD A;  2OJW A;  4LNO A;  1HTQ A;  1RL9 A;  2UU7 A;  4RF9 A;  3L2E A;  2D33 A;  2D3B A;  1P50 A;  4LNK A;  4XYC A;  4GW0 A;  1SD0 A;  4LNI A;  4GVZ A;  2J1Q A;  3IG5 A;  1I0E A;  3JQ3 A;  3NZT A;  4GW2 A;  1VA6 A;  4AM1 A;  4HPP A;  3ZXV A;  1QH4 A;  2D3C A;  1F1H A;  2D3A A;  4BG4 B;  1V4G A;  1U6R A;  3ZXR A;  3LVW A;  4LNF A;  2LGS A;  4BG4 A;  4BHL A;  3B6R A;  3L2E B;  4Z9M A;  3NG0 A;  3LN7 A;  4S0R A;  4GVY A;  1G0W A;  1VRP A;  2QC8 A;  2GLS A;  4RF6 A;  3M10 A;  2GWC A;  4LNN A;  5J9A A;  1HTO A;  3IG8 A;  3DRE A;  2WGS A;  3LVV A;  5J99 A;  3LN6 A;  1R8G A;  3DRB A;  4ACF A;  2D32 A;  1FPY A;  4S17 A;  3FKY A;  1LGR A;  4Q2R A;  3JU5 A;  4RF8 A;  3JU6 A; 
#chains in the Genus database with same CATH homology
 4BAX A;  2GWC A;  1V4G A;  2D3B A;  3LVW A;  3IG8 A;  1TT4 A;  3LVV A;  3LN6 A;  3LN7 A;  1R8G A;  3IG5 A;  3NZT A;  2D32 A;  1VA6 A;  2D3C A;  2OJW A;  2GWD A;  3FKY A;  2QC8 A;  2D3A A;  2UU7 A;  2D33 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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