2GWCA

Crystal structure of plant glutamate cysteine ligase in complex with a transition state analogue
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
438
structure length
438
Chain Sequence
b'ATEPLTREDLIAYLASGCKSKEKWRIGTEHEKFGFEVNTLRPMKYDQIAELLNSIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGMGFQPKWRREDIPTMPKGRYDIMRNYMPKVGSLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYALDVPMYFAYRNGKYVDCTGMTFRQFLAGKLPCLPGELPTYNDWENHLTTIFPEVRLKRYMEMRGADGGPWRRLCALPAFWVGLLYDEDVLQSVLDLTADWTPAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEVGFLNAVTEVVRTGVTPAENLLEMYNGEWGQSVDPVFQELLY'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Glutamate cysteine ligase
publication title Structural basis for the redox control of plant glutamate cysteine ligase.
pubmed doi rcsb
source organism Brassica juncea
molecule tags Ligase
total genus 139
structure length 438
sequence length 438
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04107 GCS2 Glutamate-cysteine ligase family 2(GCS2)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2gwcA00
1R8GA 2D32A 3LN7A 3NZTA 2D33A 2GWCA 1TT4A 2GWDA 1V4GA 1VA6A 3LN6A
chains in the Genus database with same CATH superfamily
4Q2RA 4BG4A 1CRKA 3NG0A 4LNKA 4BHLA 1P52A 3L2DA 2D32A 3LN7A 4RF9A 4ACFA 1U6RA 4AM1A 2D3BA 3JU5A 2QC8A 1HTOA 1M15A 2CRKA 1R8GA 1QH4A 1BG0A 1G0WA 1SD0A 3M10A 4LNFA 1FPYA 2BVCA 4LNIA 2LGSA 4RF7A 3IG5A 3DREA 1RL9A 2GLSA 1QK1A 4GW2A 3LN6A 2D3CA 2WHIA 3JQ3A 2WGSA 3JU6A 3B6RA 1P50A 1VRPA 3IG8A 2GWDA 4LNNA 1F1HA 3L2EB 2D33A 4Z9MA 2GWCA 1TT4A 5J99A 3JPZA 3FKYA 4XYCA 2J1QA 3LVVA 4S17A 1F52A 4S0RA 4BAXA 4RF8A 3ZXRA 4GVYA 4LNOA 3L2EA 3ZXVA 3LVWA 2UU7A 4RF6A 4HPPA 3NZTA 1LGRA 4BG4B 2D3AA 1HTQA 2OJWA 4GVZA 4GW0A 3DRBA 5J9AA 1I0EA 1V4GA 1VA6A
chains in the Genus database with same CATH topology
2QC8A 1V4GA 1R8GA 3LVWA 3IG8A 2GWDA 2UU7A 2D32A 3LN7A 3NZTA 2D33A 2GWCA 1TT4A 2D3AA 3FKYA 2OJWA 3IG5A 3LVVA 2D3BA 4BAXA 3LN6A 1VA6A 2D3CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R8G A;  2D32 A;  3LN7 A;  3NZT A;  2D33 A;  2GWC A;  1TT4 A;  2GWD A;  1V4G A;  1VA6 A;  3LN6 A; 
#chains in the Genus database with same CATH topology
 4Q2R A;  4BG4 A;  1CRK A;  3NG0 A;  4LNK A;  4BHL A;  1P52 A;  3L2D A;  2D32 A;  3LN7 A;  4RF9 A;  4ACF A;  1U6R A;  4AM1 A;  2D3B A;  3JU5 A;  2QC8 A;  1HTO A;  1M15 A;  2CRK A;  1R8G A;  1QH4 A;  1BG0 A;  1G0W A;  1SD0 A;  3M10 A;  4LNF A;  1FPY A;  2BVC A;  4LNI A;  2LGS A;  4RF7 A;  3IG5 A;  3DRE A;  1RL9 A;  2GLS A;  1QK1 A;  4GW2 A;  3LN6 A;  2D3C A;  2WHI A;  3JQ3 A;  2WGS A;  3JU6 A;  3B6R A;  1P50 A;  1VRP A;  3IG8 A;  2GWD A;  4LNN A;  1F1H A;  3L2E B;  2D33 A;  4Z9M A;  2GWC A;  1TT4 A;  5J99 A;  3JPZ A;  3FKY A;  4XYC A;  2J1Q A;  3LVV A;  4S17 A;  1F52 A;  4S0R A;  4BAX A;  4RF8 A;  3ZXR A;  4GVY A;  4LNO A;  3L2E A;  3ZXV A;  3LVW A;  2UU7 A;  4RF6 A;  4HPP A;  3NZT A;  1LGR A;  4BG4 B;  2D3A A;  1HTQ A;  2OJW A;  4GVZ A;  4GW0 A;  3DRB A;  5J9A A;  1I0E A;  1V4G A;  1VA6 A; 
#chains in the Genus database with same CATH homology
 2QC8 A;  1V4G A;  1R8G A;  3LVW A;  3IG8 A;  2GWD A;  2UU7 A;  2D32 A;  3LN7 A;  3NZT A;  2D33 A;  2GWC A;  1TT4 A;  2D3A A;  3FKY A;  2OJW A;  3IG5 A;  3LVV A;  2D3B A;  4BAX A;  3LN6 A;  1VA6 A;  2D3C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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