3LN6A

Crystal structure of a bifunctional glutathione synthetase from streptococcus agalactiae
Total Genus 204
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
204
sequence length
747
structure length
743
Chain Sequence
DRLLQRSHSHLPILQATFGLERESLRIHQPTQRVAQTPHPKTLGSRNYHPYIQTDYSEPQLELITPIAKDSQEAIRFLKAISDVAGRSINHDEYLWPLSMPPKVREEDIQIAQLEDAFEYDYRKYLEKTYGKLIQSISGIHYNLGLGQELLTSLFELSQADNAIDFQNQLYMKLSQNFLRYRWLLTYLYGASPVAEEDFLDQKLNNPVRSLRNSHLGYVNHKDIRISYTSLKDYVNDLENAVKSGQAEKEFYSPVRLRGSKACRNYLEKGITYLEFRTFDLNPFSPIGITQETVDTVHLFLLALLWIDSHIDQDIKEANRLNDLIALSHPLEKLPNQAPVSDLVDAMQSVIQHFNLSPYYQDLLESVKRQIQSPELTVAGQLLEMIEGLSLETFGQRQGQIYHDYAWEAPYALKGYETMELSTQLLLFDVIQKGVNFEVLDEQDQFLKLWHNSHIEYVKNGNMTSKDNYIVPLAMANKVVTKKILDEKHFPTPFGDEFTDRKEALNYFSQIQDKPIVVKPKSTNFGLGISIFKTSANLASYEKAIDIAFTEDSAILVEEYIEGTEYRFFVLEGDCIAVLLRVAANVVGDGIHTISQLVKLKNQNPLRGYDHRSPLEVIELGEVEQLMLEQQGYTVNSIPPEGTKIELRRNSNISTGGDSIDVTNTMDPTYKQLAAEMAEAMGAWVCGVDLIIPNATQAYSKDKKNATCIELNFNPLMYMHTYCQEGPGQSITPRILAKLFPEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structures of two bifunctional gamma-Glutamate-cysteine Ligase/Glutathione synthetases (GshF) reveal a novel hybrid ATP-grasp fold
rcsb
source organism Streptococcus agalactiae serogroup v
molecule tags Ligase
molecule keywords Glutathione biosynthesis bifunctional protein gshAB
total genus 204
structure length 743
sequence length 747
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2010-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01071 GARS_A Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
A PF18419 ATP-grasp_6 ATP-grasp-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 3ln6A01
3LN7A 1R8GA 3LN6A 2D32A 1VA6A 2GWCA 3NZTA 2GWDA 1V4GA 2D33A 1TT4A
chains in the Genus database with same CATH superfamily
1CRKA 1HTOA 4RF9A 4BHLA 2UU7A 1G0WA 3DRBA 2D3BA 4XYCA 3DREA 3ZXVA 3JU5A 1F52A 1LGRA 1U6RA 1P50A 2GWDA 2D3AA 4GW2A 3LN6A 2WHIA 4RF6A 1QK1A 4HPPA 2BVCA 1I0EA 2D3CA 2CRKA 2QC8A 4BG4A 4RF8A 3JQ3A 5J9AA 1HTQA 1F1HA 3ZXRA 3IG8A 1RL9A 3B6RA 1TT4A 1M15A 4LNFA 5J99A 3L2EB 2OJWA 1VRPA 3JPZA 4GVZA 2LGSA 4RF7A 1V4GA 3LN7A 3LVVA 1P52A 2WGSA 1QH4A 2J1QA 4LNOA 3L2DA 4S17A 4LNNA 4S0RA 3JU6A 3FKYA 3NZTA 4ACFA 4Q2RA 4BAXA 2GLSA 1VA6A 4Z9MA 4BG4B 1BG0A 1R8GA 1FPYA 1SD0A 4LNIA 4GVYA 4GW0A 3LVWA 2D32A 4LNKA 4AM1A 2GWCA 3IG5A 3L2EA 3NG0A 3M10A 2D33A
chains in the Genus database with same CATH topology
2D3CA 2QC8A 2UU7A 3FKYA 2D3BA 3NZTA 4BAXA 2OJWA 1VA6A 1V4GA 3LN7A 1R8GA 3LVVA 2GWDA 2D3AA 3IG8A 3LVWA 3LN6A 2D32A 2GWCA 3IG5A 1TT4A 2D33A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LN7 A;  1R8G A;  3LN6 A;  2D32 A;  1VA6 A;  2GWC A;  3NZT A;  2GWD A;  1V4G A;  2D33 A;  1TT4 A; 
#chains in the Genus database with same CATH topology
 1CRK A;  1HTO A;  4RF9 A;  4BHL A;  2UU7 A;  1G0W A;  3DRB A;  2D3B A;  4XYC A;  3DRE A;  3ZXV A;  3JU5 A;  1F52 A;  1LGR A;  1U6R A;  1P50 A;  2GWD A;  2D3A A;  4GW2 A;  3LN6 A;  2WHI A;  4RF6 A;  1QK1 A;  4HPP A;  2BVC A;  1I0E A;  2D3C A;  2CRK A;  2QC8 A;  4BG4 A;  4RF8 A;  3JQ3 A;  5J9A A;  1HTQ A;  1F1H A;  3ZXR A;  3IG8 A;  1RL9 A;  3B6R A;  1TT4 A;  1M15 A;  4LNF A;  5J99 A;  3L2E B;  2OJW A;  1VRP A;  3JPZ A;  4GVZ A;  2LGS A;  4RF7 A;  1V4G A;  3LN7 A;  3LVV A;  1P52 A;  2WGS A;  1QH4 A;  2J1Q A;  4LNO A;  3L2D A;  4S17 A;  4LNN A;  4S0R A;  3JU6 A;  3FKY A;  3NZT A;  4ACF A;  4Q2R A;  4BAX A;  2GLS A;  1VA6 A;  4Z9M A;  4BG4 B;  1BG0 A;  1R8G A;  1FPY A;  1SD0 A;  4LNI A;  4GVY A;  4GW0 A;  3LVW A;  2D32 A;  4LNK A;  4AM1 A;  2GWC A;  3IG5 A;  3L2E A;  3NG0 A;  3M10 A;  2D33 A; 
#chains in the Genus database with same CATH homology
 2D3C A;  2QC8 A;  2UU7 A;  3FKY A;  2D3B A;  3NZT A;  4BAX A;  2OJW A;  1VA6 A;  1V4G A;  3LN7 A;  1R8G A;  3LVV A;  2GWD A;  2D3A A;  3IG8 A;  3LVW A;  3LN6 A;  2D32 A;  2GWC A;  3IG5 A;  1TT4 A;  2D33 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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