1P52A

Structure of arginine kinase e314d mutant
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVDLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGDHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase.
pubmed doi rcsb
source organism Limulus polyphemus
molecule tags Transferase
molecule keywords Arginine kinase
total genus 128
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2003-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1p52A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1p52A02
4Z9MA 1SD0A 4HPPA 4LNIA 4LNKA 1CRKA 1LGRA 4S0RA 2WGSA 1QK1A 1HTQA 3JQ3A 3JU6A 4AM1A 1QH4A 4BG4B 4ACFA 1G0WA 2J1QA 2LGSA 1F52A 3JU5A 4Q2RA 1FPYA 2WHIA 4LNOA 1F1HA 3ZXVA 4XYCA 3ZXRA 1P50A 3L2EA 3M10A 4RF6A 1P52A 3DREA 4GVZA 4GW2A 4RF9A 4BG4A 2BVCA 1I0EA 3L2DA 3L2EB 1VRPA 1BG0A 3DRBA 2CRKA 3B6RA 5J99A 5J9AA 1HTOA 3NG0A 1RL9A 4GVYA 3JPZA 4RF7A 4LNNA 4RF8A 2GLSA 4BHLA 1U6RA 4GW0A 4S17A 1M15A 4LNFA
chains in the Genus database with same CATH superfamily
4HPPA 1SD0A 1CRKA 4S0RA 1HTQA 3JU6A 1R8GA 1F52A 3ZXVA 3LN7A 4XYCA 4RF9A 4GW2A 1I0EA 3JPZA 4LNNA 4RF8A 2D33A 1M15A 4Z9MA 1QK1A 2OJWA 3NZTA 2QC8A 4AM1A 1FPYA 1F1HA 1P52A 2BVCA 2GWCA 3L2DA 3L2EB 2D3CA 2CRKA 3IG5A 3FKYA 1U6RA 2LGSA 4GW0A 4LNFA 2D3BA 4LNIA 1LGRA 3LN6A 2GWDA 1TT4A 1QH4A 1G0WA 3IG8A 2WHIA 4BAXA 3M10A 4RF6A 4GVZA 4BG4A 1V4GA 1VRPA 1BG0A 3LVVA 5J99A 1HTOA 1RL9A 2GLSA 3LVWA 4LNKA 2WGSA 2UU7A 2D3AA 3JQ3A 4BG4B 4ACFA 2J1QA 3JU5A 4Q2RA 4LNOA 3ZXRA 1P50A 3L2EA 3DREA 1VA6A 3DRBA 3B6RA 5J9AA 3NG0A 4GVYA 4RF7A 2D32A 4BHLA 4S17A
chains in the Genus database with same CATH topology
4Z9MA 1SD0A 4HPPA 4LNIA 4LNKA 1CRKA 1LGRA 4S0RA 2WGSA 1QK1A 1HTQA 3JQ3A 3JU6A 4AM1A 1QH4A 4BG4B 4ACFA 1G0WA 2J1QA 2LGSA 1F52A 3JU5A 4Q2RA 1FPYA 2WHIA 4LNOA 1F1HA 3ZXVA 4XYCA 3ZXRA 1P50A 3L2EA 3M10A 4RF6A 1P52A 3DREA 4GVZA 4GW2A 4RF9A 4BG4A 2BVCA 1I0EA 3L2DA 3L2EB 1VRPA 1BG0A 3DRBA 2CRKA 3B6RA 5J99A 5J9AA 1HTOA 3NG0A 1RL9A 4GVYA 3JPZA 4RF7A 4LNNA 4RF8A 2GLSA 4BHLA 1U6RA 4GW0A 4S17A 1M15A 4LNFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z9M A;  1SD0 A;  4HPP A;  4LNI A;  4LNK A;  1CRK A;  1LGR A;  4S0R A;  2WGS A;  1QK1 A;  1HTQ A;  3JQ3 A;  3JU6 A;  4AM1 A;  1QH4 A;  4BG4 B;  4ACF A;  1G0W A;  2J1Q A;  2LGS A;  1F52 A;  3JU5 A;  4Q2R A;  1FPY A;  2WHI A;  4LNO A;  1F1H A;  3ZXV A;  4XYC A;  3ZXR A;  1P50 A;  3L2E A;  3M10 A;  4RF6 A;  1P52 A;  3DRE A;  4GVZ A;  4GW2 A;  4RF9 A;  4BG4 A;  2BVC A;  1I0E A;  3L2D A;  3L2E B;  1VRP A;  1BG0 A;  3DRB A;  2CRK A;  3B6R A;  5J99 A;  5J9A A;  1HTO A;  3NG0 A;  1RL9 A;  4GVY A;  3JPZ A;  4RF7 A;  4LNN A;  4RF8 A;  2GLS A;  4BHL A;  1U6R A;  4GW0 A;  4S17 A;  1M15 A;  4LNF A; 
#chains in the Genus database with same CATH topology
 4HPP A;  1SD0 A;  1CRK A;  4S0R A;  1HTQ A;  3JU6 A;  1R8G A;  1F52 A;  3ZXV A;  3LN7 A;  4XYC A;  4RF9 A;  4GW2 A;  1I0E A;  3JPZ A;  4LNN A;  4RF8 A;  2D33 A;  1M15 A;  4Z9M A;  1QK1 A;  2OJW A;  3NZT A;  2QC8 A;  4AM1 A;  1FPY A;  1F1H A;  1P52 A;  2BVC A;  2GWC A;  3L2D A;  3L2E B;  2D3C A;  2CRK A;  3IG5 A;  3FKY A;  1U6R A;  2LGS A;  4GW0 A;  4LNF A;  2D3B A;  4LNI A;  1LGR A;  3LN6 A;  2GWD A;  1TT4 A;  1QH4 A;  1G0W A;  3IG8 A;  2WHI A;  4BAX A;  3M10 A;  4RF6 A;  4GVZ A;  4BG4 A;  1V4G A;  1VRP A;  1BG0 A;  3LVV A;  5J99 A;  1HTO A;  1RL9 A;  2GLS A;  3LVW A;  4LNK A;  2WGS A;  2UU7 A;  2D3A A;  3JQ3 A;  4BG4 B;  4ACF A;  2J1Q A;  3JU5 A;  4Q2R A;  4LNO A;  3ZXR A;  1P50 A;  3L2E A;  3DRE A;  1VA6 A;  3DRB A;  3B6R A;  5J9A A;  3NG0 A;  4GVY A;  4RF7 A;  2D32 A;  4BHL A;  4S17 A; 
#chains in the Genus database with same CATH homology
 4Z9M A;  1SD0 A;  4HPP A;  4LNI A;  4LNK A;  1CRK A;  1LGR A;  4S0R A;  2WGS A;  1QK1 A;  1HTQ A;  3JQ3 A;  3JU6 A;  4AM1 A;  1QH4 A;  4BG4 B;  4ACF A;  1G0W A;  2J1Q A;  2LGS A;  1F52 A;  3JU5 A;  4Q2R A;  1FPY A;  2WHI A;  4LNO A;  1F1H A;  3ZXV A;  4XYC A;  3ZXR A;  1P50 A;  3L2E A;  3M10 A;  4RF6 A;  1P52 A;  3DRE A;  4GVZ A;  4GW2 A;  4RF9 A;  4BG4 A;  2BVC A;  1I0E A;  3L2D A;  3L2E B;  1VRP A;  1BG0 A;  3DRB A;  2CRK A;  3B6R A;  5J99 A;  5J9A A;  1HTO A;  3NG0 A;  1RL9 A;  4GVY A;  3JPZ A;  4RF7 A;  4LNN A;  4RF8 A;  2GLS A;  4BHL A;  1U6R A;  4GW0 A;  4S17 A;  1M15 A;  4LNF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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