1P52A

Structure of arginine kinase e314d mutant
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
356
structure length
356
Chain Sequence
b'VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVDLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGDHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginine kinase
publication title The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase.
pubmed doi rcsb
source organism Limulus polyphemus
molecule tags Transferase
total genus 128
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2003-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1p52A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1p52A02
4GVZA 3JQ3A 1I0EA 1BG0A 1RL9A 4LNFA 4S17A 2J1QA 4ACFA 2WHIA 4LNKA 3JU5A 5J9AA 4S0RA 2CRKA 1SD0A 3JU6A 4BG4B 4RF8A 1P52A 3L2EB 3ZXRA 3JPZA 4GVYA 1F1HA 5J99A 2BVCA 4LNIA 3ZXVA 4GW2A 3L2DA 2LGSA 4LNOA 4Q2RA 4Z9MA 4BHLA 1P50A 4RF9A 4AM1A 1QK1A 4HPPA 4XYCA 1M15A 3M10A 1FPYA 3DRBA 1CRKA 1HTQA 2GLSA 1G0WA 1QH4A 1HTOA 3DREA 4RF7A 4BG4A 1U6RA 4RF6A 4LNNA 2WGSA 1VRPA 1LGRA 3NG0A 3L2EA 1F52A 3B6RA 4GW0A
chains in the Genus database with same CATH superfamily
4GVZA 3JQ3A 2J1QA 4LNKA 3JU5A 5J9AA 4S0RA 2CRKA 1P52A 2UU7A 1F1HA 3LVWA 4LNIA 3LN6A 2GWDA 4Q2RA 2QC8A 4BHLA 4HPPA 1FPYA 3DRBA 1CRKA 1HTQA 2OJWA 1G0WA 3DREA 2D3AA 2WGSA 1F52A 1RL9A 4BG4B 3ZXVA 4GW2A 3L2DA 2LGSA 4LNOA 3LVVA 3FKYA 4XYCA 2D33A 4RF7A 1LGRA 3NG0A 3L2EA 1TT4A 4GW0A 1I0EA 4LNFA 2WHIA 1SD0A 3LN7A 3L2EB 1V4GA 3ZXRA 3JPZA 4Z9MA 1R8GA 4RF9A 1M15A 3IG8A 1VA6A 3IG5A 4LNNA 1QH4A 4RF6A 1VRPA 2GWCA 2D32A 1BG0A 4S17A 4BAXA 4ACFA 3JU6A 4RF8A 2D3CA 4GVYA 5J99A 2BVCA 1P50A 3NZTA 4AM1A 1QK1A 2D3BA 3M10A 2GLSA 1HTOA 4BG4A 1U6RA 3B6RA
chains in the Genus database with same CATH topology
4GVZA 3JQ3A 1I0EA 1BG0A 1RL9A 4LNFA 4S17A 2J1QA 4ACFA 2WHIA 4LNKA 3JU5A 5J9AA 4S0RA 2CRKA 1SD0A 3JU6A 4BG4B 4RF8A 1P52A 3L2EB 3ZXRA 3JPZA 4GVYA 1F1HA 5J99A 2BVCA 4LNIA 3ZXVA 4GW2A 3L2DA 2LGSA 4LNOA 4Q2RA 4Z9MA 4BHLA 1P50A 4RF9A 4AM1A 1QK1A 4HPPA 4XYCA 1M15A 3M10A 1FPYA 3DRBA 1CRKA 1HTQA 2GLSA 1G0WA 1QH4A 1HTOA 3DREA 4RF7A 4BG4A 1U6RA 4RF6A 4LNNA 2WGSA 1VRPA 1LGRA 3NG0A 3L2EA 1F52A 3B6RA 4GW0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GVZ A;  3JQ3 A;  1I0E A;  1BG0 A;  1RL9 A;  4LNF A;  4S17 A;  2J1Q A;  4ACF A;  2WHI A;  4LNK A;  3JU5 A;  5J9A A;  4S0R A;  2CRK A;  1SD0 A;  3JU6 A;  4BG4 B;  4RF8 A;  1P52 A;  3L2E B;  3ZXR A;  3JPZ A;  4GVY A;  1F1H A;  5J99 A;  2BVC A;  4LNI A;  3ZXV A;  4GW2 A;  3L2D A;  2LGS A;  4LNO A;  4Q2R A;  4Z9M A;  4BHL A;  1P50 A;  4RF9 A;  4AM1 A;  1QK1 A;  4HPP A;  4XYC A;  1M15 A;  3M10 A;  1FPY A;  3DRB A;  1CRK A;  1HTQ A;  2GLS A;  1G0W A;  1QH4 A;  1HTO A;  3DRE A;  4RF7 A;  4BG4 A;  1U6R A;  4RF6 A;  4LNN A;  2WGS A;  1VRP A;  1LGR A;  3NG0 A;  3L2E A;  1F52 A;  3B6R A;  4GW0 A; 
#chains in the Genus database with same CATH topology
 4GVZ A;  3JQ3 A;  2J1Q A;  4LNK A;  3JU5 A;  5J9A A;  4S0R A;  2CRK A;  1P52 A;  2UU7 A;  1F1H A;  3LVW A;  4LNI A;  3LN6 A;  2GWD A;  4Q2R A;  2QC8 A;  4BHL A;  4HPP A;  1FPY A;  3DRB A;  1CRK A;  1HTQ A;  2OJW A;  1G0W A;  3DRE A;  2D3A A;  2WGS A;  1F52 A;  1RL9 A;  4BG4 B;  3ZXV A;  4GW2 A;  3L2D A;  2LGS A;  4LNO A;  3LVV A;  3FKY A;  4XYC A;  2D33 A;  4RF7 A;  1LGR A;  3NG0 A;  3L2E A;  1TT4 A;  4GW0 A;  1I0E A;  4LNF A;  2WHI A;  1SD0 A;  3LN7 A;  3L2E B;  1V4G A;  3ZXR A;  3JPZ A;  4Z9M A;  1R8G A;  4RF9 A;  1M15 A;  3IG8 A;  1VA6 A;  3IG5 A;  4LNN A;  1QH4 A;  4RF6 A;  1VRP A;  2GWC A;  2D32 A;  1BG0 A;  4S17 A;  4BAX A;  4ACF A;  3JU6 A;  4RF8 A;  2D3C A;  4GVY A;  5J99 A;  2BVC A;  1P50 A;  3NZT A;  4AM1 A;  1QK1 A;  2D3B A;  3M10 A;  2GLS A;  1HTO A;  4BG4 A;  1U6R A;  3B6R A; 
#chains in the Genus database with same CATH homology
 4GVZ A;  3JQ3 A;  1I0E A;  1BG0 A;  1RL9 A;  4LNF A;  4S17 A;  2J1Q A;  4ACF A;  2WHI A;  4LNK A;  3JU5 A;  5J9A A;  4S0R A;  2CRK A;  1SD0 A;  3JU6 A;  4BG4 B;  4RF8 A;  1P52 A;  3L2E B;  3ZXR A;  3JPZ A;  4GVY A;  1F1H A;  5J99 A;  2BVC A;  4LNI A;  3ZXV A;  4GW2 A;  3L2D A;  2LGS A;  4LNO A;  4Q2R A;  4Z9M A;  4BHL A;  1P50 A;  4RF9 A;  4AM1 A;  1QK1 A;  4HPP A;  4XYC A;  1M15 A;  3M10 A;  1FPY A;  3DRB A;  1CRK A;  1HTQ A;  2GLS A;  1G0W A;  1QH4 A;  1HTO A;  3DRE A;  4RF7 A;  4BG4 A;  1U6R A;  4RF6 A;  4LNN A;  2WGS A;  1VRP A;  1LGR A;  3NG0 A;  3L2E A;  1F52 A;  3B6R A;  4GW0 A; 
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similar chains in the Genus database (?% sequence similarity)
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