3LN7A

Crystal structure of a bifunctional glutathione synthetase from pasteurella multocida
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
755
structure length
747
Chain Sequence
KIQHIIHENQLGLLFQQGSFGLEKESQRVTADGAIVTTPHPAVFGNRRYHPYIQTDFAESQLELITPPTKKLEDTFRWLSVIHEVVQRSLPEEEYIFPLSMPAGLPAIRVAQLDNPEDVAYREYLVKIYGKNKQMVSGIHYNFQLSPDLITRLFRLQNEYQSAVDFQNDLYLKMAKNFLRYQWILLYLLAATPTYFKDGSPLAKGQFVRSLRSSQYGYVNDPEINVSFDSVEKYVESLEHWVSTKLIAEKEFYSNVRLRGAKKAREFLTTGIQYLEFRLFDLNPFEIYGISLKDAKFIHVFALFMIWMDHTADQEEVELGKARLAEVAFEHPLEKTAYAVEGELVLLELLSMLEQIGAEPELFEIVKEKLTQFTDPSKTVAGRLVRAIEQAGSDQQLGAQLAQQYKAQAFERFYALSAFDNMELSTQALLFDVIQKGIHTEILDENDQFLCLKYGDHIEYVKNGNMTSHDSYISPLIMENKVVTKKVLQKAGFNVPQSVEFTSLEKAVASYALFENRAVVIKPKSTNYGLGITIFQQGVQNREDFAKALEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVVGDSVHSVAELVAMKNDHPLRGDGSRTPLKKIALGEIEQLQLKEQGLTIDSIPAKDQLVQLRANSNISTGGDSIDMTDEMHESYKQLAVGITKAMGAAVCGVDLIIPDLKQPATPNLTSWGVIEANFNPMMMMHIFPYAGKSRRLTQNVIKMLFPEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Glutathione biosynthesis bifunctional protein gshAB
publication title Structures of two bifunctional gamma-Glutamate-cysteine Ligase/Glutathione synthetases (GshF) reveal a novel hybrid ATP-grasp fold
rcsb
source organism Pasteurella multocida
molecule tags Ligase
total genus 166
structure length 747
sequence length 755
chains with identical sequence B
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2010-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02655 ATP-grasp_3 ATP-grasp domain
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
A PF18419 ATP-grasp_6 ATP-grasp-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 3ln7A01
1R8GA 1VA6A 2GWDA 3LN6A 2D33A 3NZTA 3LN7A 2GWCA 2D32A 1TT4A 1V4GA
chains in the Genus database with same CATH superfamily
2WHIA 4LNOA 2GWDA 4BAXA 4RF8A 2BVCA 2LGSA 1VRPA 3FKYA 3LN7A 2GWCA 1HTOA 1M15A 1U6RA 4GVYA 1FPYA 4LNNA 3DREA 4LNFA 3LVVA 1HTQA 3JU5A 2OJWA 3NG0A 3JQ3A 1G0WA 4RF9A 1F52A 1VA6A 1QH4A 4AM1A 3L2DA 1BG0A 1V4GA 2D3BA 1R8GA 1I0EA 1RL9A 4RF6A 1P52A 3L2EB 4GVZA 4XYCA 4GW0A 2D33A 1TT4A 4S0RA 5J9AA 1F1HA 3M10A 4Q2RA 5J99A 4LNKA 4ACFA 4LNIA 3ZXVA 3LVWA 4BG4B 4HPPA 2D3CA 2D32A 1QK1A 4S17A 1CRKA 3ZXRA 3LN6A 4RF7A 2D3AA 2GLSA 2UU7A 3DRBA 4BHLA 1SD0A 3B6RA 4Z9MA 2WGSA 3JPZA 2CRKA 1P50A 3JU6A 2J1QA 3IG5A 1LGRA 2QC8A 3IG8A 4BG4A 3NZTA 3L2EA 4GW2A
chains in the Genus database with same CATH topology
2GWDA 4BAXA 3LN6A 2D3AA 2UU7A 1VA6A 3FKYA 3LN7A 2GWCA 2D3BA 1V4GA 1R8GA 3LVWA 3IG5A 2D3CA 2D32A 3LVVA 2QC8A 3IG8A 2D33A 3NZTA 2OJWA 1TT4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R8G A;  1VA6 A;  2GWD A;  3LN6 A;  2D33 A;  3NZT A;  3LN7 A;  2GWC A;  2D32 A;  1TT4 A;  1V4G A; 
#chains in the Genus database with same CATH topology
 2WHI A;  4LNO A;  2GWD A;  4BAX A;  4RF8 A;  2BVC A;  2LGS A;  1VRP A;  3FKY A;  3LN7 A;  2GWC A;  1HTO A;  1M15 A;  1U6R A;  4GVY A;  1FPY A;  4LNN A;  3DRE A;  4LNF A;  3LVV A;  1HTQ A;  3JU5 A;  2OJW A;  3NG0 A;  3JQ3 A;  1G0W A;  4RF9 A;  1F52 A;  1VA6 A;  1QH4 A;  4AM1 A;  3L2D A;  1BG0 A;  1V4G A;  2D3B A;  1R8G A;  1I0E A;  1RL9 A;  4RF6 A;  1P52 A;  3L2E B;  4GVZ A;  4XYC A;  4GW0 A;  2D33 A;  1TT4 A;  4S0R A;  5J9A A;  1F1H A;  3M10 A;  4Q2R A;  5J99 A;  4LNK A;  4ACF A;  4LNI A;  3ZXV A;  3LVW A;  4BG4 B;  4HPP A;  2D3C A;  2D32 A;  1QK1 A;  4S17 A;  1CRK A;  3ZXR A;  3LN6 A;  4RF7 A;  2D3A A;  2GLS A;  2UU7 A;  3DRB A;  4BHL A;  1SD0 A;  3B6R A;  4Z9M A;  2WGS A;  3JPZ A;  2CRK A;  1P50 A;  3JU6 A;  2J1Q A;  3IG5 A;  1LGR A;  2QC8 A;  3IG8 A;  4BG4 A;  3NZT A;  3L2E A;  4GW2 A; 
#chains in the Genus database with same CATH homology
 2GWD A;  4BAX A;  3LN6 A;  2D3A A;  2UU7 A;  1VA6 A;  3FKY A;  3LN7 A;  2GWC A;  2D3B A;  1V4G A;  1R8G A;  3LVW A;  3IG5 A;  2D3C A;  2D32 A;  3LVV A;  2QC8 A;  3IG8 A;  2D33 A;  3NZT A;  2OJW A;  1TT4 A; 
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