3LN7A

Crystal structure of a bifunctional glutathione synthetase from pasteurella multocida
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
755
structure length
747
Chain Sequence
b'KIQHIIHENQLGLLFQQGSFGLEKESQRVTADGAIVTTPHPAVFGNRRYHPYIQTDFAESQLELITPPTKKLEDTFRWLSVIHEVVQRSLPEEEYIFPLSMPAGLPAIRVAQLDNPEDVAYREYLVKIYGKNKQMVSGIHYNFQLSPDLITRLFRLQNEYQSAVDFQNDLYLKMAKNFLRYQWILLYLLAATPTYFKDGSPLAKGQFVRSLRSSQYGYVNDPEINVSFDSVEKYVESLEHWVSTKLIAEKEFYSNVRLRGAKKAREFLTTGIQYLEFRLFDLNPFEIYGISLKDAKFIHVFALFMIWMDHTADQEEVELGKARLAEVAFEHPLEKTAYAVEGELVLLELLSMLEQIGAEPELFEIVKEKLTQFTDPSKTVAGRLVRAIEQAGSDQQLGAQLAQQYKAQAFERFYALSAFDNMELSTQALLFDVIQKGIHTEILDENDQFLCLKYGDHIEYVKNGNMTSHDSYISPLIMENKVVTKKVLQKAGFNVPQSVEFTSLEKAVASYALFENRAVVIKPKSTNYGLGITIFQQGVQNREDFAKALEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVVGDSVHSVAELVAMKNDHPLRGDGSRTPLKKIALGEIEQLQLKEQGLTIDSIPAKDQLVQLRANSNISTGGDSIDMTDEMHESYKQLAVGITKAMGAAVCGVDLIIPDLKQPATPNLTSWGVIEANFNPMMMMHIFPYAGKSRRLTQNVIKMLFPEL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Glutathione biosynthesis bifunctional protein gshAB
publication title Structures of two bifunctional gamma-Glutamate-cysteine Ligase/Glutathione synthetases (GshF) reveal a novel hybrid ATP-grasp fold
rcsb
source organism Pasteurella multocida
molecule tags Ligase
total genus 166
structure length 747
sequence length 755
chains with identical sequence B
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2010-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02655 ATP-grasp_3 ATP-grasp domain
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
A PF18419 ATP-grasp_6 ATP-grasp-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 3ln7A01
2GWDA 1V4GA 1VA6A 1TT4A 3LN7A 2D33A 2D32A 3LN6A 1R8GA 2GWCA 3NZTA
chains in the Genus database with same CATH superfamily
5J9AA 2BVCA 4GW2A 4LNKA 2WGSA 4GVZA 4S0RA 2D32A 4LNNA 3ZXVA 2D33A 1G0WA 3NZTA 2J1QA 3DREA 4RF8A 4RF7A 3L2EB 4Q2RA 4LNIA 3LN6A 3JU6A 2D3CA 4BG4A 3L2DA 2CRKA 1F1HA 3JQ3A 1TT4A 4GW0A 3DRBA 1R8GA 4BAXA 4LNOA 1LGRA 3B6RA 4S17A 1VA6A 2LGSA 2D3BA 1M15A 4ACFA 3JPZA 4HPPA 4XYCA 1V4GA 3M10A 1I0EA 2GWDA 1P50A 1CRKA 3NG0A 2D3AA 2QC8A 4BG4B 3LN7A 4RF6A 1QH4A 4RF9A 2GWCA 2WHIA 1FPYA 4BHLA 5J99A 1P52A 1BG0A 1QK1A 2GLSA 4AM1A 1VRPA 3IG5A 2UU7A 3JU5A 1HTOA 1RL9A 3FKYA 1SD0A 3LVVA 3IG8A 3ZXRA 4LNFA 4GVYA 3L2EA 1U6RA 4Z9MA 2OJWA 1HTQA 3LVWA 1F52A
chains in the Genus database with same CATH topology
1V4GA 3LN6A 3IG5A 2UU7A 2GWDA 2D3CA 2D32A 3FKYA 2D3AA 3LVVA 3IG8A 1TT4A 2QC8A 3LN7A 2D33A 1R8GA 4BAXA 2GWCA 3NZTA 1VA6A 2D3BA 2OJWA 3LVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GWD A;  1V4G A;  1VA6 A;  1TT4 A;  3LN7 A;  2D33 A;  2D32 A;  3LN6 A;  1R8G A;  2GWC A;  3NZT A; 
#chains in the Genus database with same CATH topology
 5J9A A;  2BVC A;  4GW2 A;  4LNK A;  2WGS A;  4GVZ A;  4S0R A;  2D32 A;  4LNN A;  3ZXV A;  2D33 A;  1G0W A;  3NZT A;  2J1Q A;  3DRE A;  4RF8 A;  4RF7 A;  3L2E B;  4Q2R A;  4LNI A;  3LN6 A;  3JU6 A;  2D3C A;  4BG4 A;  3L2D A;  2CRK A;  1F1H A;  3JQ3 A;  1TT4 A;  4GW0 A;  3DRB A;  1R8G A;  4BAX A;  4LNO A;  1LGR A;  3B6R A;  4S17 A;  1VA6 A;  2LGS A;  2D3B A;  1M15 A;  4ACF A;  3JPZ A;  4HPP A;  4XYC A;  1V4G A;  3M10 A;  1I0E A;  2GWD A;  1P50 A;  1CRK A;  3NG0 A;  2D3A A;  2QC8 A;  4BG4 B;  3LN7 A;  4RF6 A;  1QH4 A;  4RF9 A;  2GWC A;  2WHI A;  1FPY A;  4BHL A;  5J99 A;  1P52 A;  1BG0 A;  1QK1 A;  2GLS A;  4AM1 A;  1VRP A;  3IG5 A;  2UU7 A;  3JU5 A;  1HTO A;  1RL9 A;  3FKY A;  1SD0 A;  3LVV A;  3IG8 A;  3ZXR A;  4LNF A;  4GVY A;  3L2E A;  1U6R A;  4Z9M A;  2OJW A;  1HTQ A;  3LVW A;  1F52 A; 
#chains in the Genus database with same CATH homology
 1V4G A;  3LN6 A;  3IG5 A;  2UU7 A;  2GWD A;  2D3C A;  2D32 A;  3FKY A;  2D3A A;  3LVV A;  3IG8 A;  1TT4 A;  2QC8 A;  3LN7 A;  2D33 A;  1R8G A;  4BAX A;  2GWC A;  3NZT A;  1VA6 A;  2D3B A;  2OJW A;  3LVW A; 
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