1KU1A

Crystal structure of the sec7 domain of yeast gea2
Total Genus 74
20406080100120140160180200010203040506070
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
211
structure length
211
Chain Sequence
GLVPRGSHMDRKTEFIECTNAFNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKTIGLLLCHPDKVSLLNEYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAYCENQDYDPSKISDNAEDDISTVQPDADSVFILSYSIIMLNTDLHNPQVKEHMSFEDYSGNLKGCCNHKDFPFWYLDRVYCSIRDKEIVMP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Endocytosis/exocytosis
source organism Saccharomyces cerevisiae
publication title Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.
pubmed doi rcsb
molecule keywords ARF guanine-nucleotide exchange factor 2
total genus 74
structure length 211
sequence length 211
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1ku1A01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1ku1A02
4D7QA 4C0AA 3SWVA 4C7PA 4A4PA 4Z21A 4JMIA 4JMOA 2R09A 1PBVA 1KU1A 1R8QE 3LTLA 4L5MA 1BC9A 2R0DA 4OIYA 4JWLA 1R8ME 4JXHA 4D7RA 1R8SE 3L8NA 1RE0B 1XT0B 1S9DE 1XSZA
chains in the Genus database with same CATH superfamily
4Q2SA 1AVRA 1AOWA 1DM5A 4C0AA 3ABQA 2ZOCA 4C7PA 1AEIA 1A8AA 2R09A 1PBVA 4EVFA 1R8QE 2HYUA 1BCYA 1MCXA 1BC1A 1ANWA 1ANNA 1XJLA 3TW5A 1Q8DA 1QC7A 1R8ME 1BCWA 3USWA 1ALAA 1DK5A 4JK1X 1XT0B 2OY9A 1S9DE 1XSZA 4MDUA 4FQ0C 1R4AE 1W3WA 2ZHJA 1I4AA 1AXNA 1C1KA 1N00A 1HVGA 2QEZA 3ABOA 2RANA 4X9PA 1KU1A 1BCZA 1HM6A 3ANYA 4L5MA 1BC9A 2HYWA 2R0DA 2HYVA 3SOHB 1BC0A 2XO3A 4D7RA 2K6XA 1ANXA 1N42A 3USYA 4KMUX 1YJ0A 1YGMA 2H0LA 1UPTB 4FHRB 4HREA 4D7QA 3HJLA 3BRXA 1BC3A 3SWVA 2ZHIA 2VXGA 4EVHA 4JMIA 2IE6A 2XO2A 4KN4X 2H0KA 3ABSA 2Q4CA 1W7BA 2HSNA 4KN7X 4OIYA 1AIIA 4JXHA 2II2A 1R8SE 3L8NA 1M9IA 1N44A 1AVCA 1SAVA 1A8BA 4MDVA 2H0MA 2IICA 1HVDA 4A4PA 1BO9A 4Z21A 1HVEA 1AVHA 1LKVX 4JMOA 1G5NA 3ABRA 1HVFA 1YCNA 3LTLA 1HAKA 2IE7A 3AO0A 4JWLA 1N41A 3AJCA 1RE0B 1YIIA 1W45A
chains in the Genus database with same CATH topology
4D7QA 4C0AA 3HJLA 3SWVA 4C7PA 4A4PA 4FHRB 4Z21A 4JMIA 1LKVX 4JMOA 2R09A 1PBVA 1KU1A 1R8QE 4KN4X 3LTLA 4L5MA 1BC9A 2R0DA 2HSNA 3SOHB 4KN7X 4OIYA 3TW5A 4JWLA 1Q8DA 1R8ME 1QC7A 4JXHA 4D7RA 2K6XA 3AJCA 3USWA 1R8SE 3L8NA 1RE0B 4JK1X 3USYA 4KMUX 1XT0B 1S9DE 1XSZA 4FQ0C
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4D7Q A;  4C0A A;  3SWV A;  4C7P A;  4A4P A;  4Z21 A;  4JMI A;  4JMO A;  2R09 A;  1PBV A;  1KU1 A;  1R8Q E;  3LTL A;  4L5M A;  1BC9 A;  2R0D A;  4OIY A;  4JWL A;  1R8M E;  4JXH A;  4D7R A;  1R8S E;  3L8N A;  1RE0 B;  1XT0 B;  1S9D E;  1XSZ A; 
#chains in the Genus database with same CATH topology
 4Q2S A;  1AVR A;  1AOW A;  1DM5 A;  4C0A A;  3ABQ A;  2ZOC A;  4C7P A;  1AEI A;  1A8A A;  2R09 A;  1PBV A;  4EVF A;  1R8Q E;  2HYU A;  1BCY A;  1MCX A;  1BC1 A;  1ANW A;  1ANN A;  1XJL A;  3TW5 A;  1Q8D A;  1QC7 A;  1R8M E;  1BCW A;  3USW A;  1ALA A;  1DK5 A;  4JK1 X;  1XT0 B;  2OY9 A;  1S9D E;  1XSZ A;  4MDU A;  4FQ0 C;  1R4A E;  1W3W A;  2ZHJ A;  1I4A A;  1AXN A;  1C1K A;  1N00 A;  1HVG A;  2QEZ A;  3ABO A;  2RAN A;  4X9P A;  1KU1 A;  1BCZ A;  1HM6 A;  3ANY A;  4L5M A;  1BC9 A;  2HYW A;  2R0D A;  2HYV A;  3SOH B;  1BC0 A;  2XO3 A;  4D7R A;  2K6X A;  1ANX A;  1N42 A;  3USY A;  4KMU X;  1YJ0 A;  1YGM A;  2H0L A;  1UPT B;  4FHR B;  4HRE A;  4D7Q A;  3HJL A;  3BRX A;  1BC3 A;  3SWV A;  2ZHI A;  2VXG A;  4EVH A;  4JMI A;  2IE6 A;  2XO2 A;  4KN4 X;  2H0K A;  3ABS A;  2Q4C A;  1W7B A;  2HSN A;  4KN7 X;  4OIY A;  1AII A;  4JXH A;  2II2 A;  1R8S E;  3L8N A;  1M9I A;  1N44 A;  1AVC A;  1SAV A;  1A8B A;  4MDV A;  2H0M A;  2IIC A;  1HVD A;  4A4P A;  1BO9 A;  4Z21 A;  1HVE A;  1AVH A;  1LKV X;  4JMO A;  1G5N A;  3ABR A;  1HVF A;  1YCN A;  3LTL A;  1HAK A;  2IE7 A;  3AO0 A;  4JWL A;  1N41 A;  3AJC A;  1RE0 B;  1YII A;  1W45 A; 
#chains in the Genus database with same CATH homology
 4D7Q A;  4C0A A;  3HJL A;  3SWV A;  4C7P A;  4A4P A;  4FHR B;  4Z21 A;  4JMI A;  1LKV X;  4JMO A;  2R09 A;  1PBV A;  1KU1 A;  1R8Q E;  4KN4 X;  3LTL A;  4L5M A;  1BC9 A;  2R0D A;  2HSN A;  3SOH B;  4KN7 X;  4OIY A;  3TW5 A;  4JWL A;  1Q8D A;  1R8M E;  1QC7 A;  4JXH A;  4D7R A;  2K6X A;  3AJC A;  3USW A;  1R8S E;  3L8N A;  1RE0 B;  4JK1 X;  3USY A;  4KMU X;  1XT0 B;  1S9D E;  1XSZ A;  4FQ0 C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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