1KU1A

Crystal structure of the sec7 domain of yeast gea2
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
211
structure length
211
Chain Sequence
GLVPRGSHMDRKTEFIECTNAFNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKTIGLLLCHPDKVSLLNEYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAYCENQDYDPSKISDNAEDDISTVQPDADSVFILSYSIIMLNTDLHNPQVKEHMSFEDYSGNLKGCCNHKDFPFWYLDRVYCSIRDKEIVMP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.
pubmed doi rcsb
molecule tags Endocytosis/exocytosis
source organism Saccharomyces cerevisiae
molecule keywords ARF guanine-nucleotide exchange factor 2
total genus 74
structure length 211
sequence length 211
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1ku1A01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1ku1A02
2R09A 1RE0B 4L5MA 4C7PA 3L8NA 4D7QA 1R8QE 4OIYA 4A4PA 1PBVA 4JMIA 3LTLA 1BC9A 4JMOA 1R8ME 4C0AA 2R0DA 1R8SE 1S9DE 1XSZA 3SWVA 4JXHA 1XT0B 4JWLA 4D7RA 1KU1A 4Z21A
chains in the Genus database with same CATH superfamily
2IE7A 1W45A 4L5MA 4D7QA 3L8NA 1AEIA 1BC3A 1DK5A 2H0LA 3LTLA 2II2A 1BC9A 3ANYA 2ZHJA 4X9PA 2R0DA 2ZHIA 2K6XA 1BO9A 1AVCA 1R8SE 1XSZA 3ABSA 1AVRA 1HVEA 3ABQA 1QC7A 1N42A 1BCYA 1HM6A 1R8QE 4A4PA 1YJ0A 1PBVA 1HAKA 1M9IA 3TW5A 3ABOA 4KN7X 2VXGA 1W3WA 1YCNA 4Q2SA 4JMOA 1R8ME 4MDVA 2XO3A 3AJCA 2HYVA 4KMUX 1ANXA 1AVHA 1XT0B 3BRXA 4JWLA 1ANNA 1N44A 1BC0A 1ANWA 1I4AA 2H0KA 4EVFA 1HVDA 1N41A 3HJLA 1AOWA 1RE0B 4C7PA 4MDUA 1YIIA 1YGMA 1BC1A 1ALAA 4FQ0C 1AXNA 4JMIA 2RANA 1AIIA 1SAVA 1A8BA 1HVGA 1UPTB 1DM5A 4HREA 1BCWA 1XJLA 3ABRA 3USYA 1R4AE 1C1KA 1HVFA 2H0MA 1W7BA 4EVHA 3AO0A 3SWVA 4JXHA 1BCZA 4KN4X 1KU1A 4Z21A 4FHRB 1N00A 2ZOCA 1Q8DA 2R09A 2IE6A 2HYUA 2HYWA 4OIYA 1MCXA 2IICA 1G5NA 4C0AA 2OY9A 3USWA 1S9DE 2HSNA 1LKVX 2QEZA 2Q4CA 4D7RA 1A8AA 4JK1X 2XO2A 3SOHB
chains in the Genus database with same CATH topology
1Q8DA 2R09A 1QC7A 3HJLA 1RE0B 4L5MA 4C7PA 3L8NA 4D7QA 1R8QE 4OIYA 4A4PA 1PBVA 4FQ0C 4JMIA 3TW5A 3LTLA 4KN7X 1BC9A 4JMOA 3USYA 1R8ME 4C0AA 2R0DA 3AJCA 2K6XA 3USWA 1R8SE 1S9DE 2HSNA 1XSZA 4KMUX 3SWVA 1LKVX 4JXHA 1XT0B 4JWLA 4JK1X 4D7RA 4KN4X 1KU1A 4Z21A 4FHRB 3SOHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R09 A;  1RE0 B;  4L5M A;  4C7P A;  3L8N A;  4D7Q A;  1R8Q E;  4OIY A;  4A4P A;  1PBV A;  4JMI A;  3LTL A;  1BC9 A;  4JMO A;  1R8M E;  4C0A A;  2R0D A;  1R8S E;  1S9D E;  1XSZ A;  3SWV A;  4JXH A;  1XT0 B;  4JWL A;  4D7R A;  1KU1 A;  4Z21 A; 
#chains in the Genus database with same CATH topology
 2IE7 A;  1W45 A;  4L5M A;  4D7Q A;  3L8N A;  1AEI A;  1BC3 A;  1DK5 A;  2H0L A;  3LTL A;  2II2 A;  1BC9 A;  3ANY A;  2ZHJ A;  4X9P A;  2R0D A;  2ZHI A;  2K6X A;  1BO9 A;  1AVC A;  1R8S E;  1XSZ A;  3ABS A;  1AVR A;  1HVE A;  3ABQ A;  1QC7 A;  1N42 A;  1BCY A;  1HM6 A;  1R8Q E;  4A4P A;  1YJ0 A;  1PBV A;  1HAK A;  1M9I A;  3TW5 A;  3ABO A;  4KN7 X;  2VXG A;  1W3W A;  1YCN A;  4Q2S A;  4JMO A;  1R8M E;  4MDV A;  2XO3 A;  3AJC A;  2HYV A;  4KMU X;  1ANX A;  1AVH A;  1XT0 B;  3BRX A;  4JWL A;  1ANN A;  1N44 A;  1BC0 A;  1ANW A;  1I4A A;  2H0K A;  4EVF A;  1HVD A;  1N41 A;  3HJL A;  1AOW A;  1RE0 B;  4C7P A;  4MDU A;  1YII A;  1YGM A;  1BC1 A;  1ALA A;  4FQ0 C;  1AXN A;  4JMI A;  2RAN A;  1AII A;  1SAV A;  1A8B A;  1HVG A;  1UPT B;  1DM5 A;  4HRE A;  1BCW A;  1XJL A;  3ABR A;  3USY A;  1R4A E;  1C1K A;  1HVF A;  2H0M A;  1W7B A;  4EVH A;  3AO0 A;  3SWV A;  4JXH A;  1BCZ A;  4KN4 X;  1KU1 A;  4Z21 A;  4FHR B;  1N00 A;  2ZOC A;  1Q8D A;  2R09 A;  2IE6 A;  2HYU A;  2HYW A;  4OIY A;  1MCX A;  2IIC A;  1G5N A;  4C0A A;  2OY9 A;  3USW A;  1S9D E;  2HSN A;  1LKV X;  2QEZ A;  2Q4C A;  4D7R A;  1A8A A;  4JK1 X;  2XO2 A;  3SOH B; 
#chains in the Genus database with same CATH homology
 1Q8D A;  2R09 A;  1QC7 A;  3HJL A;  1RE0 B;  4L5M A;  4C7P A;  3L8N A;  4D7Q A;  1R8Q E;  4OIY A;  4A4P A;  1PBV A;  4FQ0 C;  4JMI A;  3TW5 A;  3LTL A;  4KN7 X;  1BC9 A;  4JMO A;  3USY A;  1R8M E;  4C0A A;  2R0D A;  3AJC A;  2K6X A;  3USW A;  1R8S E;  1S9D E;  2HSN A;  1XSZ A;  4KMU X;  3SWV A;  1LKV X;  4JXH A;  1XT0 B;  4JWL A;  4JK1 X;  4D7R A;  4KN4 X;  1KU1 A;  4Z21 A;  4FHR B;  3SOH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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