1M15A

Transition state structure of arginine kinase
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refinement of the arginine kinase transition-state analogue complex at 1.2 A resolution: mechanistic insights.
pubmed doi rcsb
molecule tags Transferase
source organism Limulus polyphemus
molecule keywords arginine kinase
total genus 132
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2002-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1m15A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1m15A02
3JPZA 4HPPA 4Z9MA 4BG4B 3NG0A 3JQ3A 4RF6A 3DREA 4RF9A 5J99A 5J9AA 3JU5A 1SD0A 2LGSA 4S0RA 4LNKA 1FPYA 3L2EB 1HTQA 4GVZA 3L2DA 4BHLA 1LGRA 2J1QA 4RF8A 2BVCA 2GLSA 1QH4A 3DRBA 4GW2A 2CRKA 2WHIA 3B6RA 4LNFA 1CRKA 4GW0A 1F1HA 4RF7A 1HTOA 1P52A 4BG4A 4LNNA 1I0EA 2WGSA 1RL9A 4GVYA 1U6RA 1BG0A 4ACFA 1P50A 3M10A 1F52A 4S17A 3L2EA 1QK1A 3JU6A 4Q2RA 4LNOA 1M15A 4XYCA 3ZXRA 3ZXVA 1VRPA 4LNIA 1G0WA 4AM1A
chains in the Genus database with same CATH superfamily
2D3BA 3IG5A 4RF6A 5J9AA 2D32A 4S0RA 1FPYA 3L2EB 2J1QA 3DRBA 1F1HA 1HTOA 1I0EA 2WGSA 4GVYA 4ACFA 3M10A 4Q2RA 3ZXVA 1M15A 1VA6A 4LNIA 3JPZA 2D3AA 4BAXA 3DREA 5J99A 3NZTA 1HTQA 4GVZA 4RF8A 2BVCA 1QH4A 4GW2A 3LN6A 2WHIA 3B6RA 3LVVA 4BG4A 4LNNA 1RL9A 1U6RA 1P50A 4S17A 3JU6A 1G0WA 4Z9MA 3FKYA 4BG4B 3LVWA 2OJWA 1SD0A 2GWDA 2LGSA 1LGRA 2D33A 2GLSA 2GWCA 2UU7A 4GW0A 4RF7A 1TT4A 1BG0A 1F52A 3ZXRA 4LNOA 4XYCA 1VRPA 2QC8A 4HPPA 3NG0A 3JQ3A 1V4GA 4RF9A 1R8GA 3JU5A 4LNKA 4BHLA 3L2DA 3LN7A 2CRKA 4LNFA 1CRKA 2D3CA 1P52A 3L2EA 1QK1A 3IG8A 4AM1A
chains in the Genus database with same CATH topology
3JPZA 4HPPA 4Z9MA 4BG4B 3NG0A 3JQ3A 4RF6A 3DREA 4RF9A 5J99A 5J9AA 3JU5A 1SD0A 2LGSA 4S0RA 4LNKA 1FPYA 3L2EB 1HTQA 4GVZA 3L2DA 4BHLA 1LGRA 2J1QA 4RF8A 2BVCA 2GLSA 1QH4A 3DRBA 4GW2A 2CRKA 2WHIA 3B6RA 4LNFA 1CRKA 4GW0A 1F1HA 4RF7A 1HTOA 1P52A 4BG4A 4LNNA 1I0EA 2WGSA 1RL9A 4GVYA 1U6RA 1BG0A 4ACFA 1P50A 3M10A 1F52A 4S17A 3L2EA 1QK1A 3JU6A 4Q2RA 4LNOA 1M15A 4XYCA 3ZXRA 3ZXVA 1VRPA 4LNIA 1G0WA 4AM1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JPZ A;  4HPP A;  4Z9M A;  4BG4 B;  3NG0 A;  3JQ3 A;  4RF6 A;  3DRE A;  4RF9 A;  5J99 A;  5J9A A;  3JU5 A;  1SD0 A;  2LGS A;  4S0R A;  4LNK A;  1FPY A;  3L2E B;  1HTQ A;  4GVZ A;  3L2D A;  4BHL A;  1LGR A;  2J1Q A;  4RF8 A;  2BVC A;  2GLS A;  1QH4 A;  3DRB A;  4GW2 A;  2CRK A;  2WHI A;  3B6R A;  4LNF A;  1CRK A;  4GW0 A;  1F1H A;  4RF7 A;  1HTO A;  1P52 A;  4BG4 A;  4LNN A;  1I0E A;  2WGS A;  1RL9 A;  4GVY A;  1U6R A;  1BG0 A;  4ACF A;  1P50 A;  3M10 A;  1F52 A;  4S17 A;  3L2E A;  1QK1 A;  3JU6 A;  4Q2R A;  4LNO A;  1M15 A;  4XYC A;  3ZXR A;  3ZXV A;  1VRP A;  4LNI A;  1G0W A;  4AM1 A; 
#chains in the Genus database with same CATH topology
 2D3B A;  3IG5 A;  4RF6 A;  5J9A A;  2D32 A;  4S0R A;  1FPY A;  3L2E B;  2J1Q A;  3DRB A;  1F1H A;  1HTO A;  1I0E A;  2WGS A;  4GVY A;  4ACF A;  3M10 A;  4Q2R A;  3ZXV A;  1M15 A;  1VA6 A;  4LNI A;  3JPZ A;  2D3A A;  4BAX A;  3DRE A;  5J99 A;  3NZT A;  1HTQ A;  4GVZ A;  4RF8 A;  2BVC A;  1QH4 A;  4GW2 A;  3LN6 A;  2WHI A;  3B6R A;  3LVV A;  4BG4 A;  4LNN A;  1RL9 A;  1U6R A;  1P50 A;  4S17 A;  3JU6 A;  1G0W A;  4Z9M A;  3FKY A;  4BG4 B;  3LVW A;  2OJW A;  1SD0 A;  2GWD A;  2LGS A;  1LGR A;  2D33 A;  2GLS A;  2GWC A;  2UU7 A;  4GW0 A;  4RF7 A;  1TT4 A;  1BG0 A;  1F52 A;  3ZXR A;  4LNO A;  4XYC A;  1VRP A;  2QC8 A;  4HPP A;  3NG0 A;  3JQ3 A;  1V4G A;  4RF9 A;  1R8G A;  3JU5 A;  4LNK A;  4BHL A;  3L2D A;  3LN7 A;  2CRK A;  4LNF A;  1CRK A;  2D3C A;  1P52 A;  3L2E A;  1QK1 A;  3IG8 A;  4AM1 A; 
#chains in the Genus database with same CATH homology
 3JPZ A;  4HPP A;  4Z9M A;  4BG4 B;  3NG0 A;  3JQ3 A;  4RF6 A;  3DRE A;  4RF9 A;  5J99 A;  5J9A A;  3JU5 A;  1SD0 A;  2LGS A;  4S0R A;  4LNK A;  1FPY A;  3L2E B;  1HTQ A;  4GVZ A;  3L2D A;  4BHL A;  1LGR A;  2J1Q A;  4RF8 A;  2BVC A;  2GLS A;  1QH4 A;  3DRB A;  4GW2 A;  2CRK A;  2WHI A;  3B6R A;  4LNF A;  1CRK A;  4GW0 A;  1F1H A;  4RF7 A;  1HTO A;  1P52 A;  4BG4 A;  4LNN A;  1I0E A;  2WGS A;  1RL9 A;  4GVY A;  1U6R A;  1BG0 A;  4ACF A;  1P50 A;  3M10 A;  1F52 A;  4S17 A;  3L2E A;  1QK1 A;  3JU6 A;  4Q2R A;  4LNO A;  1M15 A;  4XYC A;  3ZXR A;  3ZXV A;  1VRP A;  4LNI A;  1G0W A;  4AM1 A; 
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similar chains in the Genus database (?% sequence similarity)
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