1M9I | Genus

Total Genus 251

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	251
sequence length	664
structure length	664
Chain Sequence	YRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGDVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDDKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLALCGGED

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Lipid binding protein
source organism	Homo sapiens
publication title	Structural and Dynamic Changes in Human Annexin VI Induced by a Phosphorylation-Mimicking Mutation, T356D pubmed doi rcsb
molecule keywords	Annexin VI
total genus	251
structure length	664
sequence length	664
ec nomenclature
pdb deposition date	2002-07-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00191	Annexin	Annexin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA02
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA04
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA08
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA05
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA01
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA06
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA03
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1m9iA07

2ZHIA 1HAKA 2HYUA 1MCXA 2Q4CA 1ANXA 1N00A 2XO2A 1BO9A 1AVCA 1ANWA 1BCWA 3BRXA 1AVHA 1AXNA 1W45A 2ZHJA 1ANNA 1DM5A 1M9IA 1BC1A 2IE7A 2II2A 4EVFA 1N44A 1HVEA 1A8BA 1BCYA 1YJ0A 1AVRA 1BC0A 1N41A 1AOWA 1N42A 1G5NA 2H0KA 2IICA 4EVHA 1HVGA 1YIIA 1HM6A 4MDUA 1W3WA 1ALAA 1HVFA 2H0LA 1AIIA 4X9PA 2HYWA 2HYVA 2RANA 2IE6A 4MDVA 1BC3A 1I4AA 2ZOCA 1BCZA 1HVDA 1AEIA 1W7BA 4HREA 1SAVA 2H0MA 1YCNA 1XJLA 2XO3A 1A8AA 1DK5A
chains in the Genus database with same CATH superfamily

1R8ME 2XO2A 3ABQA 4D7QA 1BO9A 1AXNA 1Q8DA 1DM5A 1BC1A 4EVFA 1R8SE 1YJ0A 1BC0A 1N41A 4EVHA 1AOWA 1N42A 4C7PA 1XSZA 3ABOA 4X9PA 1UPTB 4Z21A 1BC9A 4Q2SA 2IE6A 1YGMA 4JWLA 1BCZA 3SOHB 2XO3A 1A8AA 1DK5A 2Q4CA 1N00A 1BCWA 4FHRB 1W45A 3HJLA 2II2A 2IE7A 3AJCA 3TW5A 1N44A 3ABSA 1BCYA 2H0KA 1AVRA 1HVGA 2R09A 4MDUA 1W3WA 2H0LA 1R8QE 4MDVA 1HVDA 3ABRA 1AEIA 1LKVX 2H0MA 1XT0B 2HSNA 2ZHIA 4JK1X 1ANXA 4L5MA 1C1KA 1AVCA 1ANWA 3BRXA 1AVHA 4A4PA 1ANNA 3SWVA 1R4AE 4KN4X 3ANYA 2IICA 3LTLA 1YIIA 1HM6A 1ALAA 4JXHA 1HVFA 2K6XA 2HYWA 2HYVA 1PBVA 2RANA 3USYA 1QC7A 1S9DE 2QEZA 1W7BA 4HREA 1SAVA 2OY9A 4C0AA 2ZHJA 3USWA 3AO0A 1HAKA 2HYUA 1MCXA 1KU1A 1M9IA 1HVEA 1A8BA 1G5NA 4OIYA 4D7RA 4KN7X 1AIIA 2R0DA 4JMOA 3L8NA 1RE0B 4JMIA 1BC3A 1I4AA 4FQ0C 2ZOCA 4KMUX 2VXGA 1YCNA 1XJLA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2ZHI A;  1HAK A;  2HYU A;  1MCX A;  2Q4C A;  1ANX A;  1N00 A;  2XO2 A;  1BO9 A;  1AVC A;  1ANW A;  1BCW A;  3BRX A;  1AVH A;  1AXN A;  1W45 A;  2ZHJ A;  1ANN A;  1DM5 A;  1M9I A;  1BC1 A;  2IE7 A;  2II2 A;  4EVF A;  1N44 A;  1HVE A;  1A8B A;  1BCY A;  1YJ0 A;  1AVR A;  1BC0 A;  1N41 A;  1AOW A;  1N42 A;  1G5N A;  2H0K A;  2IIC A;  4EVH A;  1HVG A;  1YII A;  1HM6 A;  4MDU A;  1W3W A;  1ALA A;  1HVF A;  2H0L A;  1AII A;  4X9P A;  2HYW A;  2HYV A;  2RAN A;  2IE6 A;  4MDV A;  1BC3 A;  1I4A A;  2ZOC A;  1BCZ A;  1HVD A;  1AEI A;  1W7B A;  4HRE A;  1SAV A;  2H0M A;  1YCN A;  1XJL A;  2XO3 A;  1A8A A;  1DK5 A; 
#chains in the Genus database with same CATH topology
 1R8M E;  2XO2 A;  3ABQ A;  4D7Q A;  1BO9 A;  1AXN A;  1Q8D A;  1DM5 A;  1BC1 A;  4EVF A;  1R8S E;  1YJ0 A;  1BC0 A;  1N41 A;  4EVH A;  1AOW A;  1N42 A;  4C7P A;  1XSZ A;  3ABO A;  4X9P A;  1UPT B;  4Z21 A;  1BC9 A;  4Q2S A;  2IE6 A;  1YGM A;  4JWL A;  1BCZ A;  3SOH B;  2XO3 A;  1A8A A;  1DK5 A;  2Q4C A;  1N00 A;  1BCW A;  4FHR B;  1W45 A;  3HJL A;  2II2 A;  2IE7 A;  3AJC A;  3TW5 A;  1N44 A;  3ABS A;  1BCY A;  2H0K A;  1AVR A;  1HVG A;  2R09 A;  4MDU A;  1W3W A;  2H0L A;  1R8Q E;  4MDV A;  1HVD A;  3ABR A;  1AEI A;  1LKV X;  2H0M A;  1XT0 B;  2HSN A;  2ZHI A;  4JK1 X;  1ANX A;  4L5M A;  1C1K A;  1AVC A;  1ANW A;  3BRX A;  1AVH A;  4A4P A;  1ANN A;  3SWV A;  1R4A E;  4KN4 X;  3ANY A;  2IIC A;  3LTL A;  1YII A;  1HM6 A;  1ALA A;  4JXH A;  1HVF A;  2K6X A;  2HYW A;  2HYV A;  1PBV A;  2RAN A;  3USY A;  1QC7 A;  1S9D E;  2QEZ A;  1W7B A;  4HRE A;  1SAV A;  2OY9 A;  4C0A A;  2ZHJ A;  3USW A;  3AO0 A;  1HAK A;  2HYU A;  1MCX A;  1KU1 A;  1M9I A;  1HVE A;  1A8B A;  1G5N A;  4OIY A;  4D7R A;  4KN7 X;  1AII A;  2R0D A;  4JMO A;  3L8N A;  1RE0 B;  4JMI A;  1BC3 A;  1I4A A;  4FQ0 C;  2ZOC A;  4KMU X;  2VXG A;  1YCN A;  1XJL A; 
#chains in the Genus database with same CATH homology
 2ZHI A;  1HAK A;  2HYU A;  1MCX A;  2Q4C A;  1ANX A;  1N00 A;  2XO2 A;  1BO9 A;  1AVC A;  1ANW A;  1BCW A;  3BRX A;  1AVH A;  1AXN A;  1W45 A;  2ZHJ A;  1ANN A;  1DM5 A;  1M9I A;  1BC1 A;  2IE7 A;  2II2 A;  4EVF A;  1N44 A;  1HVE A;  1A8B A;  1BCY A;  1YJ0 A;  1AVR A;  1BC0 A;  1N41 A;  1AOW A;  1N42 A;  1G5N A;  2H0K A;  2IIC A;  4EVH A;  1HVG A;  1YII A;  1HM6 A;  4MDU A;  1W3W A;  1ALA A;  1HVF A;  2H0L A;  1AII A;  4X9P A;  2HYW A;  2HYV A;  2RAN A;  2IE6 A;  4MDV A;  1BC3 A;  1I4A A;  2ZOC A;  1BCZ A;  1HVD A;  1AEI A;  1W7B A;  4HRE A;  1SAV A;  2H0M A;  1YCN A;  1XJL A;  2XO3 A;  1A8A A;  1DK5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1M9IA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations