1N42A

Crystal structure of annexin v r149e mutant
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
318
structure length
318
Chain Sequence
ALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQEMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Rattus norvegicus
molecule keywords Annexin V
total genus 124
structure length 318
sequence length 318
ec nomenclature
pdb deposition date 2002-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A03
1BCZA 1DK5A 1SAVA 1HVEA 1W3WA 2HYWA 1ANWA 1BC3A 1AIIA 2H0LA 1AVRA 1AXNA 3BRXA 2ZHIA 1N42A 1HVFA 1AVHA 1HAKA 1N44A 2IE6A 2H0MA 2XO2A 4HREA 1I4AA 1W7BA 2RANA 1ANXA 2ZOCA 1A8AA 2Q4CA 1ANNA 1AVCA 1YJ0A 1YCNA 2ZHJA 2XO3A 1AOWA 1BCYA 1XJLA 2IICA 1BC1A 1A8BA 1BCWA 4MDUA 1G5NA 1BO9A 1HM6A 1YIIA 1M9IA 2II2A 1BC0A 2HYUA 1N41A 2H0KA 1W45A 4X9PA 1DM5A 1MCXA 1AEIA 2HYVA 1HVGA 2IE7A 4EVHA 1HVDA 1N00A 1ALAA 4MDVA 4EVFA
chains in the Genus database with same CATH superfamily
1SAVA 4OIYA 4JMOA 3USWA 1AIIA 1RE0B 3BRXA 1N42A 2XO2A 4Q2SA 2RANA 1W7BA 3LTLA 1A8AA 1YJ0A 1YGMA 3ABRA 2II2A 1KU1A 2R09A 4EVHA 4FQ0C 1BCZA 1DK5A 4KN4X 1W3WA 4C0AA 4KMUX 2H0LA 2IE6A 3HJLA 1HAKA 4HREA 2H0MA 3ABSA 1I4AA 2ZOCA 1ANXA 1R4AE 1R8SE 2VXGA 2Q4CA 3USYA 2XO3A 3SWVA 1HM6A 1LKVX 3ABOA 4D7RA 1BC0A 3AO0A 1S9DE 1DM5A 1MCXA 3AJCA 2IE7A 1UPTB 1N00A 2HYWA 1ALAA 4C7PA 1R8QE 3ANYA 4JWLA 1HVEA 1BC3A 4JXHA 1XT0B 1AVHA 1N44A 2OY9A 1ANNA 1BC9A 1AVCA 1YCNA 1AOWA 2QEZA 1BC1A 2R0DA 3L8NA 1YIIA 4JK1X 1M9IA 4X9PA 2H0KA 1W45A 1QC7A 1AEIA 2HYVA 1HVDA 1Q8DA 2HSNA 1PBVA 1XSZA 1C1KA 1ANWA 4L5MA 4KN7X 2K6XA 1AVRA 1AXNA 4A4PA 2ZHIA 1HVFA 1R8ME 3SOHB 2ZHJA 4D7QA 1XJLA 1BCYA 2IICA 1A8BA 1BCWA 4MDUA 1G5NA 1BO9A 4FHRB 3ABQA 2HYUA 4Z21A 1N41A 4JMIA 3TW5A 1HVGA 4MDVA 4EVFA
chains in the Genus database with same CATH topology
1BCZA 1DK5A 1SAVA 1HVEA 1W3WA 2HYWA 1ANWA 1BC3A 1AIIA 2H0LA 1AVRA 1AXNA 3BRXA 2ZHIA 1N42A 1HVFA 1AVHA 1HAKA 1N44A 2IE6A 2H0MA 2XO2A 4HREA 1I4AA 1W7BA 2RANA 1ANXA 2ZOCA 1A8AA 2Q4CA 1ANNA 1AVCA 1YJ0A 1YCNA 2ZHJA 2XO3A 1AOWA 1BCYA 1XJLA 2IICA 1BC1A 1A8BA 1BCWA 4MDUA 1G5NA 1BO9A 1HM6A 1YIIA 1M9IA 2II2A 1BC0A 2HYUA 1N41A 2H0KA 1W45A 4X9PA 1DM5A 1MCXA 1AEIA 2HYVA 1HVGA 2IE7A 4EVHA 1HVDA 1N00A 1ALAA 4MDVA 4EVFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BCZ A;  1DK5 A;  1SAV A;  1HVE A;  1W3W A;  2HYW A;  1ANW A;  1BC3 A;  1AII A;  2H0L A;  1AVR A;  1AXN A;  3BRX A;  2ZHI A;  1N42 A;  1HVF A;  1AVH A;  1HAK A;  1N44 A;  2IE6 A;  2H0M A;  2XO2 A;  4HRE A;  1I4A A;  1W7B A;  2RAN A;  1ANX A;  2ZOC A;  1A8A A;  2Q4C A;  1ANN A;  1AVC A;  1YJ0 A;  1YCN A;  2ZHJ A;  2XO3 A;  1AOW A;  1BCY A;  1XJL A;  2IIC A;  1BC1 A;  1A8B A;  1BCW A;  4MDU A;  1G5N A;  1BO9 A;  1HM6 A;  1YII A;  1M9I A;  2II2 A;  1BC0 A;  2HYU A;  1N41 A;  2H0K A;  1W45 A;  4X9P A;  1DM5 A;  1MCX A;  1AEI A;  2HYV A;  1HVG A;  2IE7 A;  4EVH A;  1HVD A;  1N00 A;  1ALA A;  4MDV A;  4EVF A; 
#chains in the Genus database with same CATH topology
 1SAV A;  4OIY A;  4JMO A;  3USW A;  1AII A;  1RE0 B;  3BRX A;  1N42 A;  2XO2 A;  4Q2S A;  2RAN A;  1W7B A;  3LTL A;  1A8A A;  1YJ0 A;  1YGM A;  3ABR A;  2II2 A;  1KU1 A;  2R09 A;  4EVH A;  4FQ0 C;  1BCZ A;  1DK5 A;  4KN4 X;  1W3W A;  4C0A A;  4KMU X;  2H0L A;  2IE6 A;  3HJL A;  1HAK A;  4HRE A;  2H0M A;  3ABS A;  1I4A A;  2ZOC A;  1ANX A;  1R4A E;  1R8S E;  2VXG A;  2Q4C A;  3USY A;  2XO3 A;  3SWV A;  1HM6 A;  1LKV X;  3ABO A;  4D7R A;  1BC0 A;  3AO0 A;  1S9D E;  1DM5 A;  1MCX A;  3AJC A;  2IE7 A;  1UPT B;  1N00 A;  2HYW A;  1ALA A;  4C7P A;  1R8Q E;  3ANY A;  4JWL A;  1HVE A;  1BC3 A;  4JXH A;  1XT0 B;  1AVH A;  1N44 A;  2OY9 A;  1ANN A;  1BC9 A;  1AVC A;  1YCN A;  1AOW A;  2QEZ A;  1BC1 A;  2R0D A;  3L8N A;  1YII A;  4JK1 X;  1M9I A;  4X9P A;  2H0K A;  1W45 A;  1QC7 A;  1AEI A;  2HYV A;  1HVD A;  1Q8D A;  2HSN A;  1PBV A;  1XSZ A;  1C1K A;  1ANW A;  4L5M A;  4KN7 X;  2K6X A;  1AVR A;  1AXN A;  4A4P A;  2ZHI A;  1HVF A;  1R8M E;  3SOH B;  2ZHJ A;  4D7Q A;  1XJL A;  1BCY A;  2IIC A;  1A8B A;  1BCW A;  4MDU A;  1G5N A;  1BO9 A;  4FHR B;  3ABQ A;  2HYU A;  4Z21 A;  1N41 A;  4JMI A;  3TW5 A;  1HVG A;  4MDV A;  4EVF A; 
#chains in the Genus database with same CATH homology
 1BCZ A;  1DK5 A;  1SAV A;  1HVE A;  1W3W A;  2HYW A;  1ANW A;  1BC3 A;  1AII A;  2H0L A;  1AVR A;  1AXN A;  3BRX A;  2ZHI A;  1N42 A;  1HVF A;  1AVH A;  1HAK A;  1N44 A;  2IE6 A;  2H0M A;  2XO2 A;  4HRE A;  1I4A A;  1W7B A;  2RAN A;  1ANX A;  2ZOC A;  1A8A A;  2Q4C A;  1ANN A;  1AVC A;  1YJ0 A;  1YCN A;  2ZHJ A;  2XO3 A;  1AOW A;  1BCY A;  1XJL A;  2IIC A;  1BC1 A;  1A8B A;  1BCW A;  4MDU A;  1G5N A;  1BO9 A;  1HM6 A;  1YII A;  1M9I A;  2II2 A;  1BC0 A;  2HYU A;  1N41 A;  2H0K A;  1W45 A;  4X9P A;  1DM5 A;  1MCX A;  1AEI A;  2HYV A;  1HVG A;  2IE7 A;  4EVH A;  1HVD A;  1N00 A;  1ALA A;  4MDV A;  4EVF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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