1N42A

Crystal structure of annexin v r149e mutant
Total Genus 124
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
318
structure length
318
Chain Sequence
ALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQEMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Rattus norvegicus
molecule keywords Annexin V
total genus 124
structure length 318
sequence length 318
ec nomenclature
pdb deposition date 2002-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n42A03
1I4AA 1W7BA 1N42A 1YJ0A 2XO2A 1BCWA 1ALAA 1HVEA 1N41A 2II2A 1YIIA 1BC1A 1BCYA 1AIIA 1DK5A 1HVDA 4MDVA 4EVFA 2HYVA 1MCXA 2ZHIA 3BRXA 2ZOCA 1HAKA 1AVCA 2IE7A 1M9IA 4EVHA 1AVHA 1N00A 1N44A 1ANWA 1SAVA 2HYWA 1ANNA 2HYUA 1A8BA 1BCZA 2ZHJA 1BC3A 1ANXA 1YCNA 2XO3A 4X9PA 1BC0A 1A8AA 1HVFA 2H0KA 1HVGA 1G5NA 1AXNA 1W3WA 2H0MA 2IICA 2RANA 1BO9A 1AEIA 2IE6A 1HM6A 4MDUA 2H0LA 1DM5A 2Q4CA 1AVRA 4HREA 1AOWA 1W45A 1XJLA
chains in the Genus database with same CATH superfamily
4C7PA 1BCWA 4D7RA 1HVEA 4KN7X 1DK5A 1HVDA 2OY9A 1HAKA 3HJLA 1AVCA 3L8NA 1N00A 1ANWA 1SAVA 2HYUA 4C0AA 1Q8DA 2HSNA 1BCZA 2VXGA 2XO3A 1A8AA 1BO9A 1DM5A 4HREA 1W45A 3TW5A 3LTLA 3SOHB 3AJCA 1I4AA 1N42A 3ABQA 4JXHA 1YIIA 1BC9A 1AIIA 4EVFA 4MDVA 1C1KA 2QEZA 2ZHIA 2ZOCA 1N44A 4JMIA 2K6XA 4JK1X 4KN4X 1S9DE 1ANXA 1YCNA 1BC0A 1HVGA 1G5NA 2IICA 1RE0B 2RANA 1KU1A 1HM6A 4MDUA 4KMUX 1QC7A 3USYA 2Q4CA 1XJLA 3ABSA 1LKVX 1W7BA 1YJ0A 1R8ME 1PBVA 1N41A 2II2A 3SWVA 3AO0A 1BC1A 1BCYA 4FQ0C 2HYVA 1MCXA 3BRXA 2IE7A 1R8SE 4L5MA 1AVHA 2HYWA 2R09A 3ANYA 1ANNA 3ABOA 1A8BA 1R4AE 1BC3A 3ABRA 1R8QE 2H0MA 1AXNA 1AEIA 3USWA 1AVRA 1UPTB 2R0DA 1XSZA 4OIYA 2XO2A 1ALAA 4Q2SA 1XT0B 1M9IA 4EVHA 4FHRB 1YGMA 4JMOA 2ZHJA 4X9PA 4A4PA 2H0KA 1HVFA 1W3WA 4JWLA 2IE6A 2H0LA 4Z21A 1AOWA 4D7QA
chains in the Genus database with same CATH topology
1I4AA 1W7BA 1N42A 1YJ0A 2XO2A 1BCWA 1ALAA 1HVEA 1N41A 2II2A 1YIIA 1BC1A 1BCYA 1AIIA 1DK5A 1HVDA 4MDVA 4EVFA 2HYVA 1MCXA 2ZHIA 3BRXA 2ZOCA 1HAKA 1AVCA 2IE7A 1M9IA 4EVHA 1AVHA 1N00A 1N44A 1ANWA 1SAVA 2HYWA 1ANNA 2HYUA 1A8BA 1BCZA 2ZHJA 1BC3A 1ANXA 1YCNA 2XO3A 4X9PA 1BC0A 1A8AA 1HVFA 2H0KA 1HVGA 1G5NA 1AXNA 1W3WA 2H0MA 2IICA 2RANA 1BO9A 1AEIA 2IE6A 1HM6A 4MDUA 2H0LA 1DM5A 2Q4CA 1AVRA 4HREA 1AOWA 1W45A 1XJLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I4A A;  1W7B A;  1N42 A;  1YJ0 A;  2XO2 A;  1BCW A;  1ALA A;  1HVE A;  1N41 A;  2II2 A;  1YII A;  1BC1 A;  1BCY A;  1AII A;  1DK5 A;  1HVD A;  4MDV A;  4EVF A;  2HYV A;  1MCX A;  2ZHI A;  3BRX A;  2ZOC A;  1HAK A;  1AVC A;  2IE7 A;  1M9I A;  4EVH A;  1AVH A;  1N00 A;  1N44 A;  1ANW A;  1SAV A;  2HYW A;  1ANN A;  2HYU A;  1A8B A;  1BCZ A;  2ZHJ A;  1BC3 A;  1ANX A;  1YCN A;  2XO3 A;  4X9P A;  1BC0 A;  1A8A A;  1HVF A;  2H0K A;  1HVG A;  1G5N A;  1AXN A;  1W3W A;  2H0M A;  2IIC A;  2RAN A;  1BO9 A;  1AEI A;  2IE6 A;  1HM6 A;  4MDU A;  2H0L A;  1DM5 A;  2Q4C A;  1AVR A;  4HRE A;  1AOW A;  1W45 A;  1XJL A; 
#chains in the Genus database with same CATH topology
 4C7P A;  1BCW A;  4D7R A;  1HVE A;  4KN7 X;  1DK5 A;  1HVD A;  2OY9 A;  1HAK A;  3HJL A;  1AVC A;  3L8N A;  1N00 A;  1ANW A;  1SAV A;  2HYU A;  4C0A A;  1Q8D A;  2HSN A;  1BCZ A;  2VXG A;  2XO3 A;  1A8A A;  1BO9 A;  1DM5 A;  4HRE A;  1W45 A;  3TW5 A;  3LTL A;  3SOH B;  3AJC A;  1I4A A;  1N42 A;  3ABQ A;  4JXH A;  1YII A;  1BC9 A;  1AII A;  4EVF A;  4MDV A;  1C1K A;  2QEZ A;  2ZHI A;  2ZOC A;  1N44 A;  4JMI A;  2K6X A;  4JK1 X;  4KN4 X;  1S9D E;  1ANX A;  1YCN A;  1BC0 A;  1HVG A;  1G5N A;  2IIC A;  1RE0 B;  2RAN A;  1KU1 A;  1HM6 A;  4MDU A;  4KMU X;  1QC7 A;  3USY A;  2Q4C A;  1XJL A;  3ABS A;  1LKV X;  1W7B A;  1YJ0 A;  1R8M E;  1PBV A;  1N41 A;  2II2 A;  3SWV A;  3AO0 A;  1BC1 A;  1BCY A;  4FQ0 C;  2HYV A;  1MCX A;  3BRX A;  2IE7 A;  1R8S E;  4L5M A;  1AVH A;  2HYW A;  2R09 A;  3ANY A;  1ANN A;  3ABO A;  1A8B A;  1R4A E;  1BC3 A;  3ABR A;  1R8Q E;  2H0M A;  1AXN A;  1AEI A;  3USW A;  1AVR A;  1UPT B;  2R0D A;  1XSZ A;  4OIY A;  2XO2 A;  1ALA A;  4Q2S A;  1XT0 B;  1M9I A;  4EVH A;  4FHR B;  1YGM A;  4JMO A;  2ZHJ A;  4X9P A;  4A4P A;  2H0K A;  1HVF A;  1W3W A;  4JWL A;  2IE6 A;  2H0L A;  4Z21 A;  1AOW A;  4D7Q A; 
#chains in the Genus database with same CATH homology
 1I4A A;  1W7B A;  1N42 A;  1YJ0 A;  2XO2 A;  1BCW A;  1ALA A;  1HVE A;  1N41 A;  2II2 A;  1YII A;  1BC1 A;  1BCY A;  1AII A;  1DK5 A;  1HVD A;  4MDV A;  4EVF A;  2HYV A;  1MCX A;  2ZHI A;  3BRX A;  2ZOC A;  1HAK A;  1AVC A;  2IE7 A;  1M9I A;  4EVH A;  1AVH A;  1N00 A;  1N44 A;  1ANW A;  1SAV A;  2HYW A;  1ANN A;  2HYU A;  1A8B A;  1BCZ A;  2ZHJ A;  1BC3 A;  1ANX A;  1YCN A;  2XO3 A;  4X9P A;  1BC0 A;  1A8A A;  1HVF A;  2H0K A;  1HVG A;  1G5N A;  1AXN A;  1W3W A;  2H0M A;  2IIC A;  2RAN A;  1BO9 A;  1AEI A;  2IE6 A;  1HM6 A;  4MDU A;  2H0L A;  1DM5 A;  2Q4C A;  1AVR A;  4HRE A;  1AOW A;  1W45 A;  1XJL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...