1N44 | Genus

Total Genus 115

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	115
sequence length	318
structure length	318
Chain Sequence	ALRGTVTDFSGFDGRADAEVLEKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__622644133670483__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__622644133670483__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/1N44/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__622644133670483__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"622644133670483","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/1N44/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__622644133670483__ ready

script 1 started

platformSpeed = 8

Viewer cachePut cache://localLOAD_/file/5cfba234ddc5d46cc79f981f/pdb.gz

Viewer cachePut https://genus.fuw.edu.pl/file/5cfba234ddc5d46cc79f981f/pdb.gz

FileManager.getAtomSetCollectionFromFile(/file/5cfba234ddc5d46cc79f981f/pdb.gz)

loadScript /static/js/j2s/core/corezip.z.js

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5cfba234ddc5d46cc79f981f/pdb.gz): 583 ms

reading 318 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

318 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 26 ms

Adding embedded #jmolscript: select ({0:317});backbone only;select *;

platformSpeed = 8

cartoonsFancy = true

sheetSmoothing = 1.0

traceAlpha = true

loadScript /static/js/j2s/core/corescriptcmd.z.js

specularPower = 9

ambientPercent = 20

antialiasDisplay = true

Script completed

Jmol script terminated

loadScript /static/js/j2s/J/g3d/HermiteRenderer.js

loadScript /static/js/j2s/J/renderbio/BioMeshRenderer.js

loadScript /static/js/j2s/J/render/MeshRenderer.js

loadScript /static/js/j2s/J/shape/Mesh.js

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lipid binding protein
source organism	Rattus norvegicus
publication title	Interfacial basic cluster in anexin V couples phospholipid binding and trimer formation on membrane surfaces pubmed doi rcsb
molecule keywords	Annexin V
total genus	115
structure length	318
sequence length	318
ec nomenclature
pdb deposition date	2002-10-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00191	Annexin	Annexin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1n44A02
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1n44A04
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1n44A01
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	1n44A03

1ALAA 2II2A 4X9PA 1W3WA 1G5NA 2HYWA 2Q4CA 1AVCA 1DK5A 1HVEA 1N41A 2ZHJA 1AVRA 1AOWA 2IE6A 1BCZA 2H0KA 1HM6A 2ZHIA 1BO9A 2IICA 2XO2A 1YIIA 1BCWA 1AVHA 1DM5A 4EVFA 1W45A 2H0LA 2HYUA 4EVHA 2ZOCA 1AXNA 1BC3A 2HYVA 1AIIA 1BCYA 1M9IA 1W7BA 1BC0A 1HVDA 1HVFA 2RANA 4MDVA 1HVGA 1SAVA 1MCXA 1A8AA 3BRXA 1YJ0A 1I4AA 2XO3A 1HAKA 1XJLA 1N00A 4MDUA 1N42A 4HREA 1ANWA 2IE7A 1BC1A 1ANNA 2H0MA 1A8BA 1N44A 1AEIA 1ANXA 1YCNA
chains in the Genus database with same CATH superfamily

3ABSA 1BC9A 4X9PA 1G5NA 2HYWA 1AVCA 1HVEA 1S9DE 4L5MA 1R4AE 1R8ME 1BCWA 1PBVA 3AJCA 2ZOCA 4FHRB 4A4PA 4KN4X 1QC7A 4JK1X 4Z21A 1I4AA 2XO3A 1XJLA 3USYA 1A8BA 2ZHIA 4EVFA 1YCNA 3ABRA 1W3WA 2K6XA 4C7PA 1BCZA 4JXHA 2H0KA 3LTLA 1HM6A 2IICA 2XO2A 1KU1A 1YIIA 2OY9A 1R8QE 1AXNA 2HYVA 1YGMA 1BCYA 1BC0A 1HVFA 4MDVA 1SAVA 1XSZA 3SOHB 3SWVA 3USWA 1ANWA 4OIYA 4KMUX 2H0MA 1XT0B 1N44A 4KN7X 1ANXA 2II2A 3TW5A 2ZHJA 1N41A 1AVRA 1AOWA 3ABOA 4C0AA 2IE6A 2R0DA 3ABQA 4JWLA 3ANYA 1DM5A 1Q8DA 4FQ0C 1W45A 2H0LA 2HYUA 4EVHA 1BC3A 1LKVX 1M9IA 1W7BA 1HVDA 2RANA 1HVGA 1MCXA 1A8AA 1C1KA 3BRXA 1YJ0A 1HAKA 1N42A 2R09A 4HREA 3HJLA 1BC1A 1R8SE 1ANNA 1ALAA 4D7QA 2Q4CA 1DK5A 3AO0A 1RE0B 1BO9A 3L8NA 1AVHA 4JMOA 1AIIA 1UPTB 4JMIA 2VXGA 1N00A 4D7RA 4MDUA 2IE7A 2HSNA 4Q2SA 2QEZA 1AEIA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1ALA A;  2II2 A;  4X9P A;  1W3W A;  1G5N A;  2HYW A;  2Q4C A;  1AVC A;  1DK5 A;  1HVE A;  1N41 A;  2ZHJ A;  1AVR A;  1AOW A;  2IE6 A;  1BCZ A;  2H0K A;  1HM6 A;  2ZHI A;  1BO9 A;  2IIC A;  2XO2 A;  1YII A;  1BCW A;  1AVH A;  1DM5 A;  4EVF A;  1W45 A;  2H0L A;  2HYU A;  4EVH A;  2ZOC A;  1AXN A;  1BC3 A;  2HYV A;  1AII A;  1BCY A;  1M9I A;  1W7B A;  1BC0 A;  1HVD A;  1HVF A;  2RAN A;  4MDV A;  1HVG A;  1SAV A;  1MCX A;  1A8A A;  3BRX A;  1YJ0 A;  1I4A A;  2XO3 A;  1HAK A;  1XJL A;  1N00 A;  4MDU A;  1N42 A;  4HRE A;  1ANW A;  2IE7 A;  1BC1 A;  1ANN A;  2H0M A;  1A8B A;  1N44 A;  1AEI A;  1ANX A;  1YCN A; 
#chains in the Genus database with same CATH topology
 3ABS A;  1BC9 A;  4X9P A;  1G5N A;  2HYW A;  1AVC A;  1HVE A;  1S9D E;  4L5M A;  1R4A E;  1R8M E;  1BCW A;  1PBV A;  3AJC A;  2ZOC A;  4FHR B;  4A4P A;  4KN4 X;  1QC7 A;  4JK1 X;  4Z21 A;  1I4A A;  2XO3 A;  1XJL A;  3USY A;  1A8B A;  2ZHI A;  4EVF A;  1YCN A;  3ABR A;  1W3W A;  2K6X A;  4C7P A;  1BCZ A;  4JXH A;  2H0K A;  3LTL A;  1HM6 A;  2IIC A;  2XO2 A;  1KU1 A;  1YII A;  2OY9 A;  1R8Q E;  1AXN A;  2HYV A;  1YGM A;  1BCY A;  1BC0 A;  1HVF A;  4MDV A;  1SAV A;  1XSZ A;  3SOH B;  3SWV A;  3USW A;  1ANW A;  4OIY A;  4KMU X;  2H0M A;  1XT0 B;  1N44 A;  4KN7 X;  1ANX A;  2II2 A;  3TW5 A;  2ZHJ A;  1N41 A;  1AVR A;  1AOW A;  3ABO A;  4C0A A;  2IE6 A;  2R0D A;  3ABQ A;  4JWL A;  3ANY A;  1DM5 A;  1Q8D A;  4FQ0 C;  1W45 A;  2H0L A;  2HYU A;  4EVH A;  1BC3 A;  1LKV X;  1M9I A;  1W7B A;  1HVD A;  2RAN A;  1HVG A;  1MCX A;  1A8A A;  1C1K A;  3BRX A;  1YJ0 A;  1HAK A;  1N42 A;  2R09 A;  4HRE A;  3HJL A;  1BC1 A;  1R8S E;  1ANN A;  1ALA A;  4D7Q A;  2Q4C A;  1DK5 A;  3AO0 A;  1RE0 B;  1BO9 A;  3L8N A;  1AVH A;  4JMO A;  1AII A;  1UPT B;  4JMI A;  2VXG A;  1N00 A;  4D7R A;  4MDU A;  2IE7 A;  2HSN A;  4Q2S A;  2QEZ A;  1AEI A; 
#chains in the Genus database with same CATH homology
 1ALA A;  2II2 A;  4X9P A;  1W3W A;  1G5N A;  2HYW A;  2Q4C A;  1AVC A;  1DK5 A;  1HVE A;  1N41 A;  2ZHJ A;  1AVR A;  1AOW A;  2IE6 A;  1BCZ A;  2H0K A;  1HM6 A;  2ZHI A;  1BO9 A;  2IIC A;  2XO2 A;  1YII A;  1BCW A;  1AVH A;  1DM5 A;  4EVF A;  1W45 A;  2H0L A;  2HYU A;  4EVH A;  2ZOC A;  1AXN A;  1BC3 A;  2HYV A;  1AII A;  1BCY A;  1M9I A;  1W7B A;  1BC0 A;  1HVD A;  1HVF A;  2RAN A;  4MDV A;  1HVG A;  1SAV A;  1MCX A;  1A8A A;  3BRX A;  1YJ0 A;  1I4A A;  2XO3 A;  1HAK A;  1XJL A;  1N00 A;  4MDU A;  1N42 A;  4HRE A;  1ANW A;  2IE7 A;  1BC1 A;  1ANN A;  2H0M A;  1A8B A;  1N44 A;  1AEI A;  1ANX A;  1YCN A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

1N44A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations