1N44A

Crystal structure of annexin v r23e mutant
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
318
structure length
318
Chain Sequence
ALRGTVTDFSGFDGRADAEVLEKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Interfacial basic cluster in anexin V couples phospholipid binding and trimer formation on membrane surfaces
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Rattus norvegicus
molecule keywords Annexin V
total genus 115
structure length 318
sequence length 318
ec nomenclature
pdb deposition date 2002-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n44A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n44A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n44A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1n44A03
1BCYA 1AIIA 2IICA 1A8BA 2H0LA 1BC1A 4MDVA 4MDUA 1I4AA 2XO2A 2II2A 2IE6A 2XO3A 1ANWA 1BC3A 1DK5A 1N00A 1DM5A 1G5NA 1SAVA 3BRXA 1MCXA 1AVRA 1HVDA 1W45A 2HYVA 1ALAA 1YJ0A 1BCWA 1AOWA 2ZHIA 1YCNA 4X9PA 2HYWA 2ZHJA 1HM6A 1AEIA 1XJLA 1N41A 2HYUA 1M9IA 4HREA 1ANNA 1A8AA 1HVEA 4EVFA 1AVCA 1ANXA 1BC0A 1BCZA 1AVHA 1W7BA 2RANA 1W3WA 2IE7A 1HVGA 2H0MA 1AXNA 1HAKA 4EVHA 2ZOCA 2Q4CA 1BO9A 1N42A 1N44A 1HVFA 1YIIA 2H0KA
chains in the Genus database with same CATH superfamily
1BCYA 4D7RA 3AO0A 1A8BA 1BC1A 1S9DE 4JWLA 2XO2A 3AJCA 4OIYA 2R0DA 1BC3A 1DK5A 1AVRA 1HVDA 1ALAA 4C7PA 1AOWA 2ZHIA 2ZHJA 4HREA 1ANNA 2HSNA 1AVCA 1BC0A 3ABQA 2H0MA 1N44A 1YIIA 1C1KA 2IICA 2OY9A 4FHRB 2II2A 4D7QA 3ABOA 2XO3A 1G5NA 1SAVA 1XSZA 3TW5A 2HYVA 1YJ0A 1BCWA 3ABRA 1YCNA 2HYWA 3ABSA 4JK1X 1HM6A 1XJLA 1N41A 1R8QE 2HYUA 1M9IA 1HVEA 1ANXA 3SWVA 2RANA 1R8ME 2ZOCA 1RE0B 2Q4CA 1N42A 4JMIA 4JXHA 2H0KA 1AIIA 3USWA 2QEZA 3USYA 2R09A 4KN4X 1PBVA 4Z21A 1N00A 1DM5A 1MCXA 1YGMA 3ANYA 3LTLA 1Q8DA 1R4AE 4JMOA 1A8AA 1R8SE 4C0AA 1W3WA 1BC9A 1AXNA 1HVFA 1LKVX 2H0LA 2VXGA 4MDVA 4MDUA 1I4AA 1XT0B 4A4PA 2IE6A 1ANWA 4KMUX 1W45A 3L8NA 4FQ0C 4X9PA 1QC7A 2K6XA 1AEIA 4KN7X 3HJLA 4EVFA 3SOHB 1BCZA 1UPTB 1AVHA 1W7BA 1KU1A 4L5MA 1HVGA 1HAKA 4EVHA 1BO9A 2IE7A 3BRXA 4Q2SA
chains in the Genus database with same CATH topology
1BCYA 1AIIA 2IICA 1A8BA 2H0LA 1BC1A 4MDVA 4MDUA 1I4AA 2XO2A 2II2A 2IE6A 2XO3A 1ANWA 1BC3A 1DK5A 1N00A 1DM5A 1G5NA 1SAVA 3BRXA 1MCXA 1AVRA 1HVDA 1W45A 2HYVA 1ALAA 1YJ0A 1BCWA 1AOWA 2ZHIA 1YCNA 4X9PA 2HYWA 2ZHJA 1HM6A 1AEIA 1XJLA 1N41A 2HYUA 1M9IA 4HREA 1ANNA 1A8AA 1HVEA 4EVFA 1AVCA 1ANXA 1BC0A 1BCZA 1AVHA 1W7BA 2RANA 1W3WA 2IE7A 1HVGA 2H0MA 1AXNA 1HAKA 4EVHA 2ZOCA 2Q4CA 1BO9A 1N42A 1N44A 1HVFA 1YIIA 2H0KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BCY A;  1AII A;  2IIC A;  1A8B A;  2H0L A;  1BC1 A;  4MDV A;  4MDU A;  1I4A A;  2XO2 A;  2II2 A;  2IE6 A;  2XO3 A;  1ANW A;  1BC3 A;  1DK5 A;  1N00 A;  1DM5 A;  1G5N A;  1SAV A;  3BRX A;  1MCX A;  1AVR A;  1HVD A;  1W45 A;  2HYV A;  1ALA A;  1YJ0 A;  1BCW A;  1AOW A;  2ZHI A;  1YCN A;  4X9P A;  2HYW A;  2ZHJ A;  1HM6 A;  1AEI A;  1XJL A;  1N41 A;  2HYU A;  1M9I A;  4HRE A;  1ANN A;  1A8A A;  1HVE A;  4EVF A;  1AVC A;  1ANX A;  1BC0 A;  1BCZ A;  1AVH A;  1W7B A;  2RAN A;  1W3W A;  2IE7 A;  1HVG A;  2H0M A;  1AXN A;  1HAK A;  4EVH A;  2ZOC A;  2Q4C A;  1BO9 A;  1N42 A;  1N44 A;  1HVF A;  1YII A;  2H0K A; 
#chains in the Genus database with same CATH topology
 1BCY A;  4D7R A;  3AO0 A;  1A8B A;  1BC1 A;  1S9D E;  4JWL A;  2XO2 A;  3AJC A;  4OIY A;  2R0D A;  1BC3 A;  1DK5 A;  1AVR A;  1HVD A;  1ALA A;  4C7P A;  1AOW A;  2ZHI A;  2ZHJ A;  4HRE A;  1ANN A;  2HSN A;  1AVC A;  1BC0 A;  3ABQ A;  2H0M A;  1N44 A;  1YII A;  1C1K A;  2IIC A;  2OY9 A;  4FHR B;  2II2 A;  4D7Q A;  3ABO A;  2XO3 A;  1G5N A;  1SAV A;  1XSZ A;  3TW5 A;  2HYV A;  1YJ0 A;  1BCW A;  3ABR A;  1YCN A;  2HYW A;  3ABS A;  4JK1 X;  1HM6 A;  1XJL A;  1N41 A;  1R8Q E;  2HYU A;  1M9I A;  1HVE A;  1ANX A;  3SWV A;  2RAN A;  1R8M E;  2ZOC A;  1RE0 B;  2Q4C A;  1N42 A;  4JMI A;  4JXH A;  2H0K A;  1AII A;  3USW A;  2QEZ A;  3USY A;  2R09 A;  4KN4 X;  1PBV A;  4Z21 A;  1N00 A;  1DM5 A;  1MCX A;  1YGM A;  3ANY A;  3LTL A;  1Q8D A;  1R4A E;  4JMO A;  1A8A A;  1R8S E;  4C0A A;  1W3W A;  1BC9 A;  1AXN A;  1HVF A;  1LKV X;  2H0L A;  2VXG A;  4MDV A;  4MDU A;  1I4A A;  1XT0 B;  4A4P A;  2IE6 A;  1ANW A;  4KMU X;  1W45 A;  3L8N A;  4FQ0 C;  4X9P A;  1QC7 A;  2K6X A;  1AEI A;  4KN7 X;  3HJL A;  4EVF A;  3SOH B;  1BCZ A;  1UPT B;  1AVH A;  1W7B A;  1KU1 A;  4L5M A;  1HVG A;  1HAK A;  4EVH A;  1BO9 A;  2IE7 A;  3BRX A;  4Q2S A; 
#chains in the Genus database with same CATH homology
 1BCY A;  1AII A;  2IIC A;  1A8B A;  2H0L A;  1BC1 A;  4MDV A;  4MDU A;  1I4A A;  2XO2 A;  2II2 A;  2IE6 A;  2XO3 A;  1ANW A;  1BC3 A;  1DK5 A;  1N00 A;  1DM5 A;  1G5N A;  1SAV A;  3BRX A;  1MCX A;  1AVR A;  1HVD A;  1W45 A;  2HYV A;  1ALA A;  1YJ0 A;  1BCW A;  1AOW A;  2ZHI A;  1YCN A;  4X9P A;  2HYW A;  2ZHJ A;  1HM6 A;  1AEI A;  1XJL A;  1N41 A;  2HYU A;  1M9I A;  4HRE A;  1ANN A;  1A8A A;  1HVE A;  4EVF A;  1AVC A;  1ANX A;  1BC0 A;  1BCZ A;  1AVH A;  1W7B A;  2RAN A;  1W3W A;  2IE7 A;  1HVG A;  2H0M A;  1AXN A;  1HAK A;  4EVH A;  2ZOC A;  2Q4C A;  1BO9 A;  1N42 A;  1N44 A;  1HVF A;  1YII A;  2H0K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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