1R8QE

Full-length arf1-gdp-mg in complex with brefeldin a and a sec7 domain
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
191
structure length
191
Chain Sequence
SKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSYSVIMLNTDLHNPNVRDKMGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
pubmed doi rcsb
molecule tags Protein transport/exchange factor
source organism Bos taurus
molecule keywords ADP-ribosylation factor 1
total genus 72
structure length 191
sequence length 191
chains with identical sequence F
ec nomenclature
pdb deposition date 2003-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1r8qE01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1r8qE02
4OIYA 4JMIA 1XT0B 4A4PA 4Z21A 1RE0B 4JXHA 3L8NA 1R8ME 4C0AA 3LTLA 1R8QE 4D7QA 1XSZA 1PBVA 1S9DE 4JWLA 2R09A 4C7PA 4D7RA 1R8SE 1BC9A 1KU1A 4JMOA 2R0DA 3SWVA 4L5MA
chains in the Genus database with same CATH superfamily
3AJCA 4FHRB 3SOHB 3ABRA 1QC7A 1HVDA 1RE0B 1A8BA 3USWA 2IE6A 1UPTB 3ABSA 1DM5A 1Q8DA 2IICA 1YCNA 1AEIA 1ANWA 2QEZA 2HYWA 1BC1A 1W45A 3BRXA 1S9DE 4JWLA 2IE7A 3ABOA 1XJLA 2XO3A 1AVHA 1HVGA 2ZHIA 1BC9A 2HYUA 1ANNA 2H0MA 2ZHJA 4L5MA 1A8AA 4FQ0C 3AO0A 4MDUA 1HAKA 1XT0B 4A4PA 1N41A 2H0LA 2VXGA 1BCZA 1YGMA 4MDVA 1R8ME 1AVCA 2Q4CA 1HVEA 2K6XA 4D7QA 1BO9A 1N42A 4EVFA 3HJLA 2OY9A 1I4AA 4C7PA 1ANXA 2HYVA 4D7RA 1R8SE 4X9PA 1C1KA 1W3WA 4JMOA 2R0DA 1DK5A 1AIIA 4OIYA 1AVRA 4JMIA 2H0KA 1N44A 4KN4X 1BC0A 1AOWA 2RANA 1YJ0A 1ALAA 4KN7X 1W7BA 1R4AE 4JK1X 1PBVA 1N00A 2ZOCA 4HREA 4EVHA 1BCYA 2R09A 1G5NA 4Q2SA 1SAVA 1KU1A 1YIIA 1BC3A 1HVFA 1BCWA 3TW5A 3USYA 4Z21A 4JXHA 3L8NA 4C0AA 2HSNA 2II2A 1R8QE 3LTLA 1M9IA 1XSZA 1HM6A 1MCXA 3ABQA 1AXNA 4KMUX 3ANYA 1LKVX 2XO2A 3SWVA
chains in the Genus database with same CATH topology
3AJCA 4FQ0C 4OIYA 4FHRB 4JMIA 1XT0B 3SOHB 1QC7A 4A4PA 3USYA 3TW5A 4Z21A 1RE0B 4JXHA 3L8NA 4KN4X 3USWA 1Q8DA 1R8ME 4C0AA 2HSNA 4KN7X 1R8QE 3LTLA 2K6XA 4D7QA 4JK1X 1XSZA 1PBVA 1S9DE 4JWLA 3HJLA 2R09A 4C7PA 4KMUX 4D7RA 1R8SE 1BC9A 1KU1A 4JMOA 1LKVX 2R0DA 3SWVA 4L5MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OIY A;  4JMI A;  1XT0 B;  4A4P A;  4Z21 A;  1RE0 B;  4JXH A;  3L8N A;  1R8M E;  4C0A A;  3LTL A;  1R8Q E;  4D7Q A;  1XSZ A;  1PBV A;  1S9D E;  4JWL A;  2R09 A;  4C7P A;  4D7R A;  1R8S E;  1BC9 A;  1KU1 A;  4JMO A;  2R0D A;  3SWV A;  4L5M A; 
#chains in the Genus database with same CATH topology
 3AJC A;  4FHR B;  3SOH B;  3ABR A;  1QC7 A;  1HVD A;  1RE0 B;  1A8B A;  3USW A;  2IE6 A;  1UPT B;  3ABS A;  1DM5 A;  1Q8D A;  2IIC A;  1YCN A;  1AEI A;  1ANW A;  2QEZ A;  2HYW A;  1BC1 A;  1W45 A;  3BRX A;  1S9D E;  4JWL A;  2IE7 A;  3ABO A;  1XJL A;  2XO3 A;  1AVH A;  1HVG A;  2ZHI A;  1BC9 A;  2HYU A;  1ANN A;  2H0M A;  2ZHJ A;  4L5M A;  1A8A A;  4FQ0 C;  3AO0 A;  4MDU A;  1HAK A;  1XT0 B;  4A4P A;  1N41 A;  2H0L A;  2VXG A;  1BCZ A;  1YGM A;  4MDV A;  1R8M E;  1AVC A;  2Q4C A;  1HVE A;  2K6X A;  4D7Q A;  1BO9 A;  1N42 A;  4EVF A;  3HJL A;  2OY9 A;  1I4A A;  4C7P A;  1ANX A;  2HYV A;  4D7R A;  1R8S E;  4X9P A;  1C1K A;  1W3W A;  4JMO A;  2R0D A;  1DK5 A;  1AII A;  4OIY A;  1AVR A;  4JMI A;  2H0K A;  1N44 A;  4KN4 X;  1BC0 A;  1AOW A;  2RAN A;  1YJ0 A;  1ALA A;  4KN7 X;  1W7B A;  1R4A E;  4JK1 X;  1PBV A;  1N00 A;  2ZOC A;  4HRE A;  4EVH A;  1BCY A;  2R09 A;  1G5N A;  4Q2S A;  1SAV A;  1KU1 A;  1YII A;  1BC3 A;  1HVF A;  1BCW A;  3TW5 A;  3USY A;  4Z21 A;  4JXH A;  3L8N A;  4C0A A;  2HSN A;  2II2 A;  1R8Q E;  3LTL A;  1M9I A;  1XSZ A;  1HM6 A;  1MCX A;  3ABQ A;  1AXN A;  4KMU X;  3ANY A;  1LKV X;  2XO2 A;  3SWV A; 
#chains in the Genus database with same CATH homology
 3AJC A;  4FQ0 C;  4OIY A;  4FHR B;  4JMI A;  1XT0 B;  3SOH B;  1QC7 A;  4A4P A;  3USY A;  3TW5 A;  4Z21 A;  1RE0 B;  4JXH A;  3L8N A;  4KN4 X;  3USW A;  1Q8D A;  1R8M E;  4C0A A;  2HSN A;  4KN7 X;  1R8Q E;  3LTL A;  2K6X A;  4D7Q A;  4JK1 X;  1XSZ A;  1PBV A;  1S9D E;  4JWL A;  3HJL A;  2R09 A;  4C7P A;  4KMU X;  4D7R A;  1R8S E;  1BC9 A;  1KU1 A;  4JMO A;  1LKV X;  2R0D A;  3SWV A;  4L5M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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