1R8S | Genus

Total Genus 69

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	69
sequence length	187
structure length	187
Chain Sequence	NRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGKAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSYSVIMLNTDLHNPNVRDKMGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPED

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 187 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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187 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein transport/exchange factor
source organism	Bos taurus
publication title	Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor pubmed doi rcsb
molecule keywords	ADP-ribosylation factor 1
total genus	69
structure length	187
sequence length	187
ec nomenclature
pdb deposition date	2003-10-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
E	PF01369	Sec7	Sec7 domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.20	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin V; domain 1	1r8sE01
1.10.1000.11	Mainly Alpha	Orthogonal Bundle	Arf Nucleotide-binding Site Opener; domain 2	Arf Nucleotide-binding Site Opener,domain 2	1r8sE02

4JMOA 4D7RA 1XT0B 2R0DA 1XSZA 1KU1A 4JXHA 3L8NA 4JWLA 1S9DE 1RE0B 1R8QE 1PBVA 4Z21A 1R8SE 2R09A 4A4PA 4OIYA 3LTLA 1R8ME 1BC9A 3SWVA 4C0AA 4C7PA 4D7QA 4L5MA 4JMIA
chains in the Genus database with same CATH superfamily

1AIIA 3USWA 1HAKA 1DK5A 2R0DA 4HREA 2XO2A 1W45A 2HYWA 1W7BA 1HVFA 1PBVA 2HYUA 1YGMA 4KMUX 2VXGA 2H0LA 4A4PA 2HYVA 2ZOCA 1M9IA 4MDUA 4Q2SA 1HVDA 3LTLA 1C1KA 2QEZA 1N42A 1ALAA 1I4AA 2XO3A 1BC9A 2HSNA 2RANA 2ZHJA 3SWVA 4C0AA 1AXNA 1BC3A 1UPTB 2H0KA 3AJCA 2II2A 4JMOA 1G5NA 1HVGA 4D7RA 1XT0B 1AVHA 1QC7A 1Q8DA 1S9DE 1A8BA 1BCWA 3ABOA 4Z21A 1HVEA 2R09A 3AO0A 1BC0A 4FQ0C 2OY9A 4EVHA 1BO9A 3USYA 1ANNA 1YIIA 2IE6A 4JK1X 1BCZA 4MDVA 3SOHB 3ABRA 1AEIA 2H0MA 1KU1A 2K6XA 1HM6A 1N44A 1RE0B 1R8QE 1R8SE 2Q4CA 4OIYA 1LKVX 2ZHIA 1SAVA 1AOWA 2IE7A 1R4AE 1DM5A 1YCNA 3BRXA 1AVRA 4X9PA 3ANYA 1XJLA 1XSZA 3HJLA 4JXHA 1ANXA 3L8NA 4JWLA 1N41A 4EVFA 1MCXA 3TW5A 1BC1A 1BCYA 1ANWA 2IICA 4KN7X 1AVCA 1W3WA 3ABQA 4FHRB 1R8ME 1N00A 4KN4X 1A8AA 4C7PA 4D7QA 4L5MA 4JMIA 3ABSA 1YJ0A
chains in the Genus database with same CATH topology

3USWA 4JMOA 4D7RA 1XT0B 1QC7A 2R0DA 1XSZA 1KU1A 3HJLA 4JXHA 2K6XA 3L8NA 4JWLA 1S9DE 1Q8DA 1RE0B 1R8QE 1PBVA 4Z21A 4KMUX 3TW5A 1R8SE 2R09A 4A4PA 4FQ0C 4OIYA 1LKVX 4KN7X 3LTLA 3USYA 4JK1X 4FHRB 1R8ME 1BC9A 2HSNA 3SWVA 4C0AA 4KN4X 4C7PA 3SOHB 4D7QA 4L5MA 3AJCA 4JMIA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4JMO A;  4D7R A;  1XT0 B;  2R0D A;  1XSZ A;  1KU1 A;  4JXH A;  3L8N A;  4JWL A;  1S9D E;  1RE0 B;  1R8Q E;  1PBV A;  4Z21 A;  1R8S E;  2R09 A;  4A4P A;  4OIY A;  3LTL A;  1R8M E;  1BC9 A;  3SWV A;  4C0A A;  4C7P A;  4D7Q A;  4L5M A;  4JMI A; 
#chains in the Genus database with same CATH topology
 1AII A;  3USW A;  1HAK A;  1DK5 A;  2R0D A;  4HRE A;  2XO2 A;  1W45 A;  2HYW A;  1W7B A;  1HVF A;  1PBV A;  2HYU A;  1YGM A;  4KMU X;  2VXG A;  2H0L A;  4A4P A;  2HYV A;  2ZOC A;  1M9I A;  4MDU A;  4Q2S A;  1HVD A;  3LTL A;  1C1K A;  2QEZ A;  1N42 A;  1ALA A;  1I4A A;  2XO3 A;  1BC9 A;  2HSN A;  2RAN A;  2ZHJ A;  3SWV A;  4C0A A;  1AXN A;  1BC3 A;  1UPT B;  2H0K A;  3AJC A;  2II2 A;  4JMO A;  1G5N A;  1HVG A;  4D7R A;  1XT0 B;  1AVH A;  1QC7 A;  1Q8D A;  1S9D E;  1A8B A;  1BCW A;  3ABO A;  4Z21 A;  1HVE A;  2R09 A;  3AO0 A;  1BC0 A;  4FQ0 C;  2OY9 A;  4EVH A;  1BO9 A;  3USY A;  1ANN A;  1YII A;  2IE6 A;  4JK1 X;  1BCZ A;  4MDV A;  3SOH B;  3ABR A;  1AEI A;  2H0M A;  1KU1 A;  2K6X A;  1HM6 A;  1N44 A;  1RE0 B;  1R8Q E;  1R8S E;  2Q4C A;  4OIY A;  1LKV X;  2ZHI A;  1SAV A;  1AOW A;  2IE7 A;  1R4A E;  1DM5 A;  1YCN A;  3BRX A;  1AVR A;  4X9P A;  3ANY A;  1XJL A;  1XSZ A;  3HJL A;  4JXH A;  1ANX A;  3L8N A;  4JWL A;  1N41 A;  4EVF A;  1MCX A;  3TW5 A;  1BC1 A;  1BCY A;  1ANW A;  2IIC A;  4KN7 X;  1AVC A;  1W3W A;  3ABQ A;  4FHR B;  1R8M E;  1N00 A;  4KN4 X;  1A8A A;  4C7P A;  4D7Q A;  4L5M A;  4JMI A;  3ABS A;  1YJ0 A; 
#chains in the Genus database with same CATH homology
 3USW A;  4JMO A;  4D7R A;  1XT0 B;  1QC7 A;  2R0D A;  1XSZ A;  1KU1 A;  3HJL A;  4JXH A;  2K6X A;  3L8N A;  4JWL A;  1S9D E;  1Q8D A;  1RE0 B;  1R8Q E;  1PBV A;  4Z21 A;  4KMU X;  3TW5 A;  1R8S E;  2R09 A;  4A4P A;  4FQ0 C;  4OIY A;  1LKV X;  4KN7 X;  3LTL A;  3USY A;  4JK1 X;  4FHR B;  1R8M E;  1BC9 A;  2HSN A;  3SWV A;  4C0A A;  4KN4 X;  4C7P A;  3SOH B;  4D7Q A;  4L5M A;  3AJC A;  4JMI A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1R8SE

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations