1R8SE

Arf1[delta1-17]-gdp in complex with a sec7 domain carrying the mutation of the catalytic glutamate to lysine
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
187
structure length
187
Chain Sequence
NRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGKAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSYSVIMLNTDLHNPNVRDKMGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
pubmed doi rcsb
molecule tags Protein transport/exchange factor
source organism Bos taurus
molecule keywords ADP-ribosylation factor 1
total genus 69
structure length 187
sequence length 187
ec nomenclature
pdb deposition date 2003-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1r8sE01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1r8sE02
2R09A 1R8ME 4JMOA 4C7PA 1BC9A 4L5MA 4A4PA 4D7QA 1XT0B 4OIYA 4C0AA 3SWVA 4JMIA 1S9DE 4D7RA 1R8QE 3LTLA 2R0DA 1PBVA 1KU1A 4JWLA 4JXHA 3L8NA 1XSZA 1RE0B 1R8SE 4Z21A
chains in the Genus database with same CATH superfamily
1Q8DA 4KN7X 3ABQA 2IICA 1I4AA 3USYA 4L5MA 4A4PA 3ABRA 1ANXA 4C0AA 1BC3A 2HSNA 4HREA 1C1KA 1AOWA 1PBVA 2VXGA 2K6XA 4FQ0C 1BCWA 2QEZA 1YJ0A 1ANWA 1M9IA 1R8SE 1N41A 1BC1A 4Z21A 2HYVA 1G5NA 2R09A 1N44A 1R8ME 1AEIA 1YIIA 3ANYA 1YGMA 4C7PA 2IE6A 1MCXA 1HVGA 1N42A 1ALAA 1S9DE 1HVFA 4D7RA 2RANA 1R8QE 1YCNA 1A8AA 2IE7A 2Q4CA 4JWLA 3L8NA 4MDVA 2HYWA 3ABOA 1HVEA 4Q2SA 1W3WA 1DK5A 4JK1X 1HAKA 2XO2A 1BC9A 3ABSA 1SAVA 1N00A 1AVHA 1W7BA 2H0LA 4JMIA 3HJLA 1A8BA 3LTLA 2R0DA 2XO3A 1XJLA 1UPTB 1BC0A 1DM5A 2II2A 2ZHJA 2OY9A 1BCYA 4JXHA 4KN4X 4FHRB 3USWA 1AIIA 1XSZA 4EVFA 1RE0B 1AVRA 2HYUA 1QC7A 4JMOA 1ANNA 4EVHA 4MDUA 1R4AE 1BCZA 3BRXA 1AXNA 4D7QA 4X9PA 1XT0B 2H0KA 4OIYA 3SWVA 3SOHB 1HM6A 1BO9A 3AO0A 1W45A 4KMUX 3AJCA 1KU1A 2ZOCA 1AVCA 1HVDA 1LKVX 2H0MA 3TW5A 2ZHIA
chains in the Genus database with same CATH topology
1Q8DA 4KN7X 2R09A 1QC7A 1R8ME 4JMOA 4C7PA 3USYA 1BC9A 4L5MA 4A4PA 4D7QA 4Z21A 1XT0B 4OIYA 4C0AA 3SWVA 3SOHB 4JMIA 3HJLA 2HSNA 1S9DE 4D7RA 1R8QE 3LTLA 2R0DA 1PBVA 4KMUX 3AJCA 1KU1A 2K6XA 4FQ0C 4JWLA 4JXHA 4KN4X 3L8NA 4FHRB 3USWA 1LKVX 1XSZA 1RE0B 3TW5A 1R8SE 4JK1X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R09 A;  1R8M E;  4JMO A;  4C7P A;  1BC9 A;  4L5M A;  4A4P A;  4D7Q A;  1XT0 B;  4OIY A;  4C0A A;  3SWV A;  4JMI A;  1S9D E;  4D7R A;  1R8Q E;  3LTL A;  2R0D A;  1PBV A;  1KU1 A;  4JWL A;  4JXH A;  3L8N A;  1XSZ A;  1RE0 B;  1R8S E;  4Z21 A; 
#chains in the Genus database with same CATH topology
 1Q8D A;  4KN7 X;  3ABQ A;  2IIC A;  1I4A A;  3USY A;  4L5M A;  4A4P A;  3ABR A;  1ANX A;  4C0A A;  1BC3 A;  2HSN A;  4HRE A;  1C1K A;  1AOW A;  1PBV A;  2VXG A;  2K6X A;  4FQ0 C;  1BCW A;  2QEZ A;  1YJ0 A;  1ANW A;  1M9I A;  1R8S E;  1N41 A;  1BC1 A;  4Z21 A;  2HYV A;  1G5N A;  2R09 A;  1N44 A;  1R8M E;  1AEI A;  1YII A;  3ANY A;  1YGM A;  4C7P A;  2IE6 A;  1MCX A;  1HVG A;  1N42 A;  1ALA A;  1S9D E;  1HVF A;  4D7R A;  2RAN A;  1R8Q E;  1YCN A;  1A8A A;  2IE7 A;  2Q4C A;  4JWL A;  3L8N A;  4MDV A;  2HYW A;  3ABO A;  1HVE A;  4Q2S A;  1W3W A;  1DK5 A;  4JK1 X;  1HAK A;  2XO2 A;  1BC9 A;  3ABS A;  1SAV A;  1N00 A;  1AVH A;  1W7B A;  2H0L A;  4JMI A;  3HJL A;  1A8B A;  3LTL A;  2R0D A;  2XO3 A;  1XJL A;  1UPT B;  1BC0 A;  1DM5 A;  2II2 A;  2ZHJ A;  2OY9 A;  1BCY A;  4JXH A;  4KN4 X;  4FHR B;  3USW A;  1AII A;  1XSZ A;  4EVF A;  1RE0 B;  1AVR A;  2HYU A;  1QC7 A;  4JMO A;  1ANN A;  4EVH A;  4MDU A;  1R4A E;  1BCZ A;  3BRX A;  1AXN A;  4D7Q A;  4X9P A;  1XT0 B;  2H0K A;  4OIY A;  3SWV A;  3SOH B;  1HM6 A;  1BO9 A;  3AO0 A;  1W45 A;  4KMU X;  3AJC A;  1KU1 A;  2ZOC A;  1AVC A;  1HVD A;  1LKV X;  2H0M A;  3TW5 A;  2ZHI A; 
#chains in the Genus database with same CATH homology
 1Q8D A;  4KN7 X;  2R09 A;  1QC7 A;  1R8M E;  4JMO A;  4C7P A;  3USY A;  1BC9 A;  4L5M A;  4A4P A;  4D7Q A;  4Z21 A;  1XT0 B;  4OIY A;  4C0A A;  3SWV A;  3SOH B;  4JMI A;  3HJL A;  2HSN A;  1S9D E;  4D7R A;  1R8Q E;  3LTL A;  2R0D A;  1PBV A;  4KMU X;  3AJC A;  1KU1 A;  2K6X A;  4FQ0 C;  4JWL A;  4JXH A;  4KN4 X;  3L8N A;  4FHR B;  3USW A;  1LKV X;  1XSZ A;  1RE0 B;  3TW5 A;  1R8S E;  4JK1 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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