1R8SE

Arf1[delta1-17]-gdp in complex with a sec7 domain carrying the mutation of the catalytic glutamate to lysine
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
187
structure length
187
Chain Sequence
NRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGKAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSYSVIMLNTDLHNPNVRDKMGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein transport/exchange factor
source organism Bos taurus
publication title Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
pubmed doi rcsb
molecule keywords ADP-ribosylation factor 1
total genus 69
structure length 187
sequence length 187
ec nomenclature
pdb deposition date 2003-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1r8sE01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1r8sE02
1RE0B 1KU1A 1R8QE 1S9DE 2R09A 3LTLA 4C7PA 3SWVA 1R8SE 4JMOA 4JWLA 4D7QA 1R8ME 4C0AA 1PBVA 3L8NA 4A4PA 4JMIA 1BC9A 4JXHA 4OIYA 1XT0B 4Z21A 2R0DA 4D7RA 1XSZA 4L5MA
chains in the Genus database with same CATH superfamily
4HREA 2K6XA 4KMUX 4EVFA 1KU1A 1AEIA 1N41A 1W3WA 1QC7A 1N42A 2ZOCA 3ABQA 2HSNA 1BCWA 2IICA 2VXGA 4Q2SA 4MDUA 1N44A 2HYUA 4KN4X 4JMOA 4JWLA 1HAKA 1ANWA 4A4PA 1XJLA 2H0KA 2II2A 3BRXA 1BC9A 4FQ0C 4JK1X 4D7RA 3USYA 1LKVX 1W7BA 3ABRA 4L5MA 1R4AE 1YJ0A 1HVGA 1RE0B 1R8QE 1M9IA 1ANNA 3USWA 1YIIA 3SWVA 1BCZA 1DK5A 1A8BA 4D7QA 1HVFA 1PBVA 1YGMA 1BC3A 1AVRA 1HVDA 3TW5A 1AVCA 4JMIA 2H0LA 2XO2A 1AVHA 1N00A 2H0MA 1A8AA 1BO9A 3AJCA 3ANYA 1AXNA 1W45A 1AOWA 1S9DE 1BC1A 1HM6A 4EVHA 2R09A 3LTLA 1SAVA 1I4AA 1Q8DA 2Q4CA 1MCXA 2XO3A 1R8ME 4C0AA 4FHRB 4KN7X 4JXHA 1XT0B 1HVEA 1DM5A 1ALAA 1AIIA 3AO0A 4MDVA 3ABSA 1YCNA 4C7PA 1BCYA 2QEZA 2ZHJA 1R8SE 1G5NA 1UPTB 3L8NA 2ZHIA 1ANXA 2RANA 2IE6A 2OY9A 3SOHB 1BC0A 2IE7A 1C1KA 3HJLA 2HYVA 2HYWA 4OIYA 2R0DA 4X9PA 4Z21A 3ABOA 1XSZA
chains in the Genus database with same CATH topology
3AJCA 2K6XA 4KMUX 1RE0B 1KU1A 1R8QE 1QC7A 1S9DE 2HSNA 2R09A 3LTLA 3USWA 4C7PA 3SWVA 1Q8DA 1R8SE 4KN4X 4JMOA 4JWLA 4D7QA 1R8ME 4C0AA 1PBVA 3L8NA 3TW5A 4FHRB 3SOHB 4KN7X 4A4PA 4JMIA 1BC9A 4JXHA 3HJLA 1XT0B 4OIYA 4FQ0C 2R0DA 4JK1X 4D7RA 3USYA 4Z21A 1LKVX 1XSZA 4L5MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RE0 B;  1KU1 A;  1R8Q E;  1S9D E;  2R09 A;  3LTL A;  4C7P A;  3SWV A;  1R8S E;  4JMO A;  4JWL A;  4D7Q A;  1R8M E;  4C0A A;  1PBV A;  3L8N A;  4A4P A;  4JMI A;  1BC9 A;  4JXH A;  4OIY A;  1XT0 B;  4Z21 A;  2R0D A;  4D7R A;  1XSZ A;  4L5M A; 
#chains in the Genus database with same CATH topology
 4HRE A;  2K6X A;  4KMU X;  4EVF A;  1KU1 A;  1AEI A;  1N41 A;  1W3W A;  1QC7 A;  1N42 A;  2ZOC A;  3ABQ A;  2HSN A;  1BCW A;  2IIC A;  2VXG A;  4Q2S A;  4MDU A;  1N44 A;  2HYU A;  4KN4 X;  4JMO A;  4JWL A;  1HAK A;  1ANW A;  4A4P A;  1XJL A;  2H0K A;  2II2 A;  3BRX A;  1BC9 A;  4FQ0 C;  4JK1 X;  4D7R A;  3USY A;  1LKV X;  1W7B A;  3ABR A;  4L5M A;  1R4A E;  1YJ0 A;  1HVG A;  1RE0 B;  1R8Q E;  1M9I A;  1ANN A;  3USW A;  1YII A;  3SWV A;  1BCZ A;  1DK5 A;  1A8B A;  4D7Q A;  1HVF A;  1PBV A;  1YGM A;  1BC3 A;  1AVR A;  1HVD A;  3TW5 A;  1AVC A;  4JMI A;  2H0L A;  2XO2 A;  1AVH A;  1N00 A;  2H0M A;  1A8A A;  1BO9 A;  3AJC A;  3ANY A;  1AXN A;  1W45 A;  1AOW A;  1S9D E;  1BC1 A;  1HM6 A;  4EVH A;  2R09 A;  3LTL A;  1SAV A;  1I4A A;  1Q8D A;  2Q4C A;  1MCX A;  2XO3 A;  1R8M E;  4C0A A;  4FHR B;  4KN7 X;  4JXH A;  1XT0 B;  1HVE A;  1DM5 A;  1ALA A;  1AII A;  3AO0 A;  4MDV A;  3ABS A;  1YCN A;  4C7P A;  1BCY A;  2QEZ A;  2ZHJ A;  1R8S E;  1G5N A;  1UPT B;  3L8N A;  2ZHI A;  1ANX A;  2RAN A;  2IE6 A;  2OY9 A;  3SOH B;  1BC0 A;  2IE7 A;  1C1K A;  3HJL A;  2HYV A;  2HYW A;  4OIY A;  2R0D A;  4X9P A;  4Z21 A;  3ABO A;  1XSZ A; 
#chains in the Genus database with same CATH homology
 3AJC A;  2K6X A;  4KMU X;  1RE0 B;  1KU1 A;  1R8Q E;  1QC7 A;  1S9D E;  2HSN A;  2R09 A;  3LTL A;  3USW A;  4C7P A;  3SWV A;  1Q8D A;  1R8S E;  4KN4 X;  4JMO A;  4JWL A;  4D7Q A;  1R8M E;  4C0A A;  1PBV A;  3L8N A;  3TW5 A;  4FHR B;  3SOH B;  4KN7 X;  4A4P A;  4JMI A;  1BC9 A;  4JXH A;  3HJL A;  1XT0 B;  4OIY A;  4FQ0 C;  2R0D A;  4JK1 X;  4D7R A;  3USY A;  4Z21 A;  1LKV X;  1XSZ A;  4L5M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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