1RE0B

Structure of arf1-gdp bound to sec7 domain complexed with brefeldin a
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
221
structure length
195
Chain Sequence
GSHMASDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism.
pubmed doi rcsb
molecule tags Protein transport
source organism Homo sapiens
molecule keywords ADP-ribosylation factor 1
total genus 75
structure length 195
sequence length 221
ec nomenclature
pdb deposition date 2003-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1re0B01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1re0B02
4JMIA 4JMOA 1R8ME 4C0AA 2R0DA 1KU1A 4JWLA 4A4PA 4JXHA 3L8NA 4D7RA 1XSZA 1S9DE 4D7QA 4OIYA 1BC9A 3LTLA 3SWVA 1XT0B 1PBVA 2R09A 4L5MA 1R8SE 1RE0B 1R8QE 4C7PA 4Z21A
chains in the Genus database with same CATH superfamily
2R0DA 1SAVA 1BC0A 1KU1A 1A8BA 2H0LA 4KN4X 3ABRA 4X9PA 1YIIA 1YCNA 4Q2SA 4FQ0C 2QEZA 1W3WA 2IE7A 2ZOCA 3AO0A 4D7RA 1XSZA 1BCZA 1R4AE 1BC1A 1BC9A 1AIIA 1ANNA 3BRXA 2H0KA 1LKVX 2ZHJA 3TW5A 2HYWA 1ANWA 1BCWA 1QC7A 2II2A 3ABQA 3USYA 1M9IA 4KMUX 1AEIA 2XO3A 1DK5A 2ZHIA 1HVDA 1AVCA 1A8AA 1HM6A 1XT0B 1PBVA 1AOWA 1AXNA 1R8SE 1RE0B 1HAKA 4C7PA 4Z21A 1N42A 3SOHB 4C0AA 1XJLA 1HVFA 3AJCA 1ANXA 4MDVA 4FHRB 3HJLA 1N44A 2IICA 1N00A 2K6XA 3ABOA 2HYUA 1I4AA 1DM5A 2HSNA 1BCYA 4EVHA 2XO2A 1HVGA 3LTLA 1W7BA 1YJ0A 3ABSA 1YGMA 2R09A 4L5MA 1MCXA 1BC3A 2HYVA 4JMIA 4JMOA 1R8ME 2Q4CA 3USWA 4EVFA 1HVEA 3ANYA 2RANA 4JWLA 1N41A 4JXHA 4A4PA 1BO9A 1C1KA 3L8NA 2OY9A 4KN7X 4JK1X 1S9DE 4D7QA 1UPTB 4OIYA 4MDUA 2VXGA 1AVRA 1AVHA 1G5NA 1W45A 3SWVA 2H0MA 2IE6A 4HREA 1Q8DA 1R8QE 1ALAA
chains in the Genus database with same CATH topology
1LKVX 4JMIA 1R8ME 4JMOA 3TW5A 4C0AA 2R0DA 3USWA 1KU1A 4KN4X 3AJCA 4JWLA 4JXHA 4A4PA 4FHRB 3HJLA 1QC7A 4FQ0C 2K6XA 3USYA 4KMUX 3L8NA 4D7RA 1XSZA 4KN7X 4JK1X 2HSNA 1S9DE 4D7QA 4OIYA 1BC9A 3LTLA 3SWVA 1XT0B 1PBVA 1Q8DA 2R09A 4L5MA 1R8SE 1RE0B 1R8QE 4C7PA 4Z21A 3SOHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JMI A;  4JMO A;  1R8M E;  4C0A A;  2R0D A;  1KU1 A;  4JWL A;  4A4P A;  4JXH A;  3L8N A;  4D7R A;  1XSZ A;  1S9D E;  4D7Q A;  4OIY A;  1BC9 A;  3LTL A;  3SWV A;  1XT0 B;  1PBV A;  2R09 A;  4L5M A;  1R8S E;  1RE0 B;  1R8Q E;  4C7P A;  4Z21 A; 
#chains in the Genus database with same CATH topology
 2R0D A;  1SAV A;  1BC0 A;  1KU1 A;  1A8B A;  2H0L A;  4KN4 X;  3ABR A;  4X9P A;  1YII A;  1YCN A;  4Q2S A;  4FQ0 C;  2QEZ A;  1W3W A;  2IE7 A;  2ZOC A;  3AO0 A;  4D7R A;  1XSZ A;  1BCZ A;  1R4A E;  1BC1 A;  1BC9 A;  1AII A;  1ANN A;  3BRX A;  2H0K A;  1LKV X;  2ZHJ A;  3TW5 A;  2HYW A;  1ANW A;  1BCW A;  1QC7 A;  2II2 A;  3ABQ A;  3USY A;  1M9I A;  4KMU X;  1AEI A;  2XO3 A;  1DK5 A;  2ZHI A;  1HVD A;  1AVC A;  1A8A A;  1HM6 A;  1XT0 B;  1PBV A;  1AOW A;  1AXN A;  1R8S E;  1RE0 B;  1HAK A;  4C7P A;  4Z21 A;  1N42 A;  3SOH B;  4C0A A;  1XJL A;  1HVF A;  3AJC A;  1ANX A;  4MDV A;  4FHR B;  3HJL A;  1N44 A;  2IIC A;  1N00 A;  2K6X A;  3ABO A;  2HYU A;  1I4A A;  1DM5 A;  2HSN A;  1BCY A;  4EVH A;  2XO2 A;  1HVG A;  3LTL A;  1W7B A;  1YJ0 A;  3ABS A;  1YGM A;  2R09 A;  4L5M A;  1MCX A;  1BC3 A;  2HYV A;  4JMI A;  4JMO A;  1R8M E;  2Q4C A;  3USW A;  4EVF A;  1HVE A;  3ANY A;  2RAN A;  4JWL A;  1N41 A;  4JXH A;  4A4P A;  1BO9 A;  1C1K A;  3L8N A;  2OY9 A;  4KN7 X;  4JK1 X;  1S9D E;  4D7Q A;  1UPT B;  4OIY A;  4MDU A;  2VXG A;  1AVR A;  1AVH A;  1G5N A;  1W45 A;  3SWV A;  2H0M A;  2IE6 A;  4HRE A;  1Q8D A;  1R8Q E;  1ALA A; 
#chains in the Genus database with same CATH homology
 1LKV X;  4JMI A;  1R8M E;  4JMO A;  3TW5 A;  4C0A A;  2R0D A;  3USW A;  1KU1 A;  4KN4 X;  3AJC A;  4JWL A;  4JXH A;  4A4P A;  4FHR B;  3HJL A;  1QC7 A;  4FQ0 C;  2K6X A;  3USY A;  4KMU X;  3L8N A;  4D7R A;  1XSZ A;  4KN7 X;  4JK1 X;  2HSN A;  1S9D E;  4D7Q A;  4OIY A;  1BC9 A;  3LTL A;  3SWV A;  1XT0 B;  1PBV A;  1Q8D A;  2R09 A;  4L5M A;  1R8S E;  1RE0 B;  1R8Q E;  4C7P A;  4Z21 A;  3SOH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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