1SD0A

Structure of arginine kinase c271a mutant
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFAPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIRMEKAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants
pubmed doi rcsb
molecule tags Transferase
source organism Limulus polyphemus
molecule keywords Arginine kinase
total genus 125
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2004-02-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1sd0A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1sd0A02
1U6RA 3JU5A 3NG0A 4LNOA 1F52A 4S0RA 2LGSA 4LNIA 4BG4A 1P50A 5J99A 4RF8A 2BVCA 2GLSA 4GW2A 1HTOA 4Q2RA 3B6RA 4GW0A 1SD0A 4ACFA 4LNFA 3JQ3A 2J1QA 4RF6A 2WHIA 3L2EA 3ZXVA 4RF9A 4BG4B 3DRBA 3JU6A 1HTQA 4BHLA 3DREA 1QK1A 4GVZA 4GVYA 1M15A 3L2DA 3ZXRA 1RL9A 3M10A 1F1HA 4Z9MA 4AM1A 4HPPA 4LNNA 1G0WA 1I0EA 4S17A 3L2EB 1FPYA 4XYCA 5J9AA 4LNKA 1VRPA 4RF7A 2WGSA 2CRKA 1LGRA 1BG0A 3JPZA 1CRKA 1QH4A 1P52A
chains in the Genus database with same CATH superfamily
1F52A 2LGSA 4GW2A 3IG5A 3ZXVA 4BG4B 4BHLA 4GVYA 3IG8A 1VA6A 4Z9MA 1R8GA 1VRPA 3LVWA 2CRKA 1LGRA 1HTQA 5J9AA 1U6RA 3JU5A 4LNOA 4LNIA 4BG4A 4RF8A 2GLSA 4GW0A 4LNFA 2J1QA 2WHIA 1TT4A 2D3CA 3M10A 3LVVA 2D33A 4RF6A 1BG0A 1CRKA 1P52A 3LN6A 1V4GA 3B6RA 3FKYA 4ACFA 3JQ3A 2UU7A 3DRBA 2OJWA 1QK1A 1M15A 3L2DA 3ZXRA 1RL9A 1F1HA 2GWCA 2QC8A 4XYCA 4LNKA 4RF7A 2WGSA 1QH4A 3NG0A 4S0RA 1P50A 5J99A 2BVCA 1HTOA 1SD0A 3LN7A 3L2EA 2D3BA 4RF9A 3JU6A 3DREA 3NZTA 4BAXA 4GVZA 4AM1A 2GWDA 4HPPA 4LNNA 1G0WA 1I0EA 4S17A 3L2EB 2D3AA 1FPYA 2D32A 4Q2RA 3JPZA
chains in the Genus database with same CATH topology
1U6RA 3JU5A 3NG0A 4LNOA 1F52A 4S0RA 2LGSA 4LNIA 4BG4A 1P50A 5J99A 4RF8A 2BVCA 2GLSA 4GW2A 1HTOA 4Q2RA 3B6RA 4GW0A 1SD0A 4ACFA 4LNFA 3JQ3A 2J1QA 4RF6A 2WHIA 3L2EA 3ZXVA 4RF9A 4BG4B 3DRBA 3JU6A 1HTQA 4BHLA 3DREA 1QK1A 4GVZA 4GVYA 1M15A 3L2DA 3ZXRA 1RL9A 3M10A 1F1HA 4Z9MA 4AM1A 4HPPA 4LNNA 1G0WA 1I0EA 4S17A 3L2EB 1FPYA 4XYCA 5J9AA 4LNKA 1VRPA 4RF7A 2WGSA 2CRKA 1LGRA 1BG0A 3JPZA 1CRKA 1QH4A 1P52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U6R A;  3JU5 A;  3NG0 A;  4LNO A;  1F52 A;  4S0R A;  2LGS A;  4LNI A;  4BG4 A;  1P50 A;  5J99 A;  4RF8 A;  2BVC A;  2GLS A;  4GW2 A;  1HTO A;  4Q2R A;  3B6R A;  4GW0 A;  1SD0 A;  4ACF A;  4LNF A;  3JQ3 A;  2J1Q A;  4RF6 A;  2WHI A;  3L2E A;  3ZXV A;  4RF9 A;  4BG4 B;  3DRB A;  3JU6 A;  1HTQ A;  4BHL A;  3DRE A;  1QK1 A;  4GVZ A;  4GVY A;  1M15 A;  3L2D A;  3ZXR A;  1RL9 A;  3M10 A;  1F1H A;  4Z9M A;  4AM1 A;  4HPP A;  4LNN A;  1G0W A;  1I0E A;  4S17 A;  3L2E B;  1FPY A;  4XYC A;  5J9A A;  4LNK A;  1VRP A;  4RF7 A;  2WGS A;  2CRK A;  1LGR A;  1BG0 A;  3JPZ A;  1CRK A;  1QH4 A;  1P52 A; 
#chains in the Genus database with same CATH topology
 1F52 A;  2LGS A;  4GW2 A;  3IG5 A;  3ZXV A;  4BG4 B;  4BHL A;  4GVY A;  3IG8 A;  1VA6 A;  4Z9M A;  1R8G A;  1VRP A;  3LVW A;  2CRK A;  1LGR A;  1HTQ A;  5J9A A;  1U6R A;  3JU5 A;  4LNO A;  4LNI A;  4BG4 A;  4RF8 A;  2GLS A;  4GW0 A;  4LNF A;  2J1Q A;  2WHI A;  1TT4 A;  2D3C A;  3M10 A;  3LVV A;  2D33 A;  4RF6 A;  1BG0 A;  1CRK A;  1P52 A;  3LN6 A;  1V4G A;  3B6R A;  3FKY A;  4ACF A;  3JQ3 A;  2UU7 A;  3DRB A;  2OJW A;  1QK1 A;  1M15 A;  3L2D A;  3ZXR A;  1RL9 A;  1F1H A;  2GWC A;  2QC8 A;  4XYC A;  4LNK A;  4RF7 A;  2WGS A;  1QH4 A;  3NG0 A;  4S0R A;  1P50 A;  5J99 A;  2BVC A;  1HTO A;  1SD0 A;  3LN7 A;  3L2E A;  2D3B A;  4RF9 A;  3JU6 A;  3DRE A;  3NZT A;  4BAX A;  4GVZ A;  4AM1 A;  2GWD A;  4HPP A;  4LNN A;  1G0W A;  1I0E A;  4S17 A;  3L2E B;  2D3A A;  1FPY A;  2D32 A;  4Q2R A;  3JPZ A; 
#chains in the Genus database with same CATH homology
 1U6R A;  3JU5 A;  3NG0 A;  4LNO A;  1F52 A;  4S0R A;  2LGS A;  4LNI A;  4BG4 A;  1P50 A;  5J99 A;  4RF8 A;  2BVC A;  2GLS A;  4GW2 A;  1HTO A;  4Q2R A;  3B6R A;  4GW0 A;  1SD0 A;  4ACF A;  4LNF A;  3JQ3 A;  2J1Q A;  4RF6 A;  2WHI A;  3L2E A;  3ZXV A;  4RF9 A;  4BG4 B;  3DRB A;  3JU6 A;  1HTQ A;  4BHL A;  3DRE A;  1QK1 A;  4GVZ A;  4GVY A;  1M15 A;  3L2D A;  3ZXR A;  1RL9 A;  3M10 A;  1F1H A;  4Z9M A;  4AM1 A;  4HPP A;  4LNN A;  1G0W A;  1I0E A;  4S17 A;  3L2E B;  1FPY A;  4XYC A;  5J9A A;  4LNK A;  1VRP A;  4RF7 A;  2WGS A;  2CRK A;  1LGR A;  1BG0 A;  3JPZ A;  1CRK A;  1QH4 A;  1P52 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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