1SD0A

Structure of arginine kinase c271a mutant
Total Genus 125
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFAPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIRMEKAAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants
pubmed doi rcsb
molecule tags Transferase
source organism Limulus polyphemus
molecule keywords Arginine kinase
total genus 125
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2004-02-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 1sd0A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 1sd0A02
4RF6A 4BHLA 5J99A 1VRPA 3M10A 4GW0A 1LGRA 1G0WA 3ZXRA 4RF9A 2CRKA 4LNOA 3B6RA 1CRKA 1U6RA 4BG4A 4BG4B 4LNNA 3ZXVA 1RL9A 1P52A 2WGSA 4LNIA 5J9AA 4Z9MA 4GW2A 1M15A 4Q2RA 4AM1A 2LGSA 4GVZA 1F52A 2GLSA 4S17A 2J1QA 3DRBA 4HPPA 4ACFA 1HTQA 3JPZA 4RF7A 3L2EB 1I0EA 1BG0A 1P50A 3L2EA 4GVYA 1FPYA 4LNKA 3JQ3A 1SD0A 1QK1A 2BVCA 1HTOA 3DREA 3JU5A 1F1HA 3L2DA 2WHIA 3JU6A 3NG0A 4LNFA 4RF8A 1QH4A 4XYCA 4S0RA
chains in the Genus database with same CATH superfamily
1VRPA 1G0WA 1R8GA 1M15A 4S17A 2J1QA 3DRBA 4BAXA 2GWDA 3IG5A 4ACFA 4LNKA 1I0EA 4GVYA 1FPYA 2GWCA 1QK1A 2BVCA 1HTOA 3L2DA 1V4GA 2D3AA 4RF8A 2UU7A 2WHIA 5J99A 4RF9A 3B6RA 1CRKA 1U6RA 3ZXVA 4BG4B 1RL9A 1P52A 4GW2A 4AM1A 2LGSA 3LVVA 3NZTA 4HPPA 3JPZA 3L2EA 2QC8A 3DREA 3JU6A 3NG0A 4LNFA 4XYCA 4RF6A 4BHLA 3M10A 4GW0A 2D33A 4LNOA 2CRKA 2WGSA 5J9AA 4Z9MA 4Q2RA 1VA6A 4GVZA 1F52A 3LVWA 3IG8A 1HTQA 4RF7A 1TT4A 3L2EB 1P50A 1F1HA 2D32A 1LGRA 3ZXRA 4BG4A 4LNNA 3LN6A 2D3CA 4LNIA 2GLSA 1BG0A 2D3BA 3JQ3A 2OJWA 1SD0A 3JU5A 3LN7A 3FKYA 1QH4A 4S0RA
chains in the Genus database with same CATH topology
4RF6A 4BHLA 5J99A 1VRPA 3M10A 4GW0A 1LGRA 1G0WA 3ZXRA 4RF9A 2CRKA 4LNOA 3B6RA 1CRKA 1U6RA 4BG4A 4BG4B 4LNNA 3ZXVA 1RL9A 1P52A 2WGSA 4LNIA 5J9AA 4Z9MA 4GW2A 1M15A 4Q2RA 4AM1A 2LGSA 4GVZA 1F52A 2GLSA 4S17A 2J1QA 3DRBA 4HPPA 4ACFA 1HTQA 3JPZA 4RF7A 3L2EB 1I0EA 1BG0A 1P50A 3L2EA 4GVYA 1FPYA 4LNKA 3JQ3A 1SD0A 1QK1A 2BVCA 1HTOA 3DREA 3JU5A 1F1HA 3L2DA 2WHIA 3JU6A 3NG0A 4LNFA 4RF8A 1QH4A 4XYCA 4S0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RF6 A;  4BHL A;  5J99 A;  1VRP A;  3M10 A;  4GW0 A;  1LGR A;  1G0W A;  3ZXR A;  4RF9 A;  2CRK A;  4LNO A;  3B6R A;  1CRK A;  1U6R A;  4BG4 A;  4BG4 B;  4LNN A;  3ZXV A;  1RL9 A;  1P52 A;  2WGS A;  4LNI A;  5J9A A;  4Z9M A;  4GW2 A;  1M15 A;  4Q2R A;  4AM1 A;  2LGS A;  4GVZ A;  1F52 A;  2GLS A;  4S17 A;  2J1Q A;  3DRB A;  4HPP A;  4ACF A;  1HTQ A;  3JPZ A;  4RF7 A;  3L2E B;  1I0E A;  1BG0 A;  1P50 A;  3L2E A;  4GVY A;  1FPY A;  4LNK A;  3JQ3 A;  1SD0 A;  1QK1 A;  2BVC A;  1HTO A;  3DRE A;  3JU5 A;  1F1H A;  3L2D A;  2WHI A;  3JU6 A;  3NG0 A;  4LNF A;  4RF8 A;  1QH4 A;  4XYC A;  4S0R A; 
#chains in the Genus database with same CATH topology
 1VRP A;  1G0W A;  1R8G A;  1M15 A;  4S17 A;  2J1Q A;  3DRB A;  4BAX A;  2GWD A;  3IG5 A;  4ACF A;  4LNK A;  1I0E A;  4GVY A;  1FPY A;  2GWC A;  1QK1 A;  2BVC A;  1HTO A;  3L2D A;  1V4G A;  2D3A A;  4RF8 A;  2UU7 A;  2WHI A;  5J99 A;  4RF9 A;  3B6R A;  1CRK A;  1U6R A;  3ZXV A;  4BG4 B;  1RL9 A;  1P52 A;  4GW2 A;  4AM1 A;  2LGS A;  3LVV A;  3NZT A;  4HPP A;  3JPZ A;  3L2E A;  2QC8 A;  3DRE A;  3JU6 A;  3NG0 A;  4LNF A;  4XYC A;  4RF6 A;  4BHL A;  3M10 A;  4GW0 A;  2D33 A;  4LNO A;  2CRK A;  2WGS A;  5J9A A;  4Z9M A;  4Q2R A;  1VA6 A;  4GVZ A;  1F52 A;  3LVW A;  3IG8 A;  1HTQ A;  4RF7 A;  1TT4 A;  3L2E B;  1P50 A;  1F1H A;  2D32 A;  1LGR A;  3ZXR A;  4BG4 A;  4LNN A;  3LN6 A;  2D3C A;  4LNI A;  2GLS A;  1BG0 A;  2D3B A;  3JQ3 A;  2OJW A;  1SD0 A;  3JU5 A;  3LN7 A;  3FKY A;  1QH4 A;  4S0R A; 
#chains in the Genus database with same CATH homology
 4RF6 A;  4BHL A;  5J99 A;  1VRP A;  3M10 A;  4GW0 A;  1LGR A;  1G0W A;  3ZXR A;  4RF9 A;  2CRK A;  4LNO A;  3B6R A;  1CRK A;  1U6R A;  4BG4 A;  4BG4 B;  4LNN A;  3ZXV A;  1RL9 A;  1P52 A;  2WGS A;  4LNI A;  5J9A A;  4Z9M A;  4GW2 A;  1M15 A;  4Q2R A;  4AM1 A;  2LGS A;  4GVZ A;  1F52 A;  2GLS A;  4S17 A;  2J1Q A;  3DRB A;  4HPP A;  4ACF A;  1HTQ A;  3JPZ A;  4RF7 A;  3L2E B;  1I0E A;  1BG0 A;  1P50 A;  3L2E A;  4GVY A;  1FPY A;  4LNK A;  3JQ3 A;  1SD0 A;  1QK1 A;  2BVC A;  1HTO A;  3DRE A;  3JU5 A;  1F1H A;  3L2D A;  2WHI A;  3JU6 A;  3NG0 A;  4LNF A;  4RF8 A;  1QH4 A;  4XYC A;  4S0R A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...