1XJLA

Structure of human annexin a2 in the presence of calcium ions
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
319
structure length
319
Chain Sequence
PSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Annexin A2: Does it induce membrane aggregation by a new multimeric state of the protein?
pubmed rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Annexin A2
total genus 131
structure length 319
sequence length 319
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1xjlA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1xjlA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1xjlA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 1xjlA03
2HYVA 1AVRA 1N42A 1HVGA 1AVHA 2ZHIA 2IICA 1BO9A 2IE6A 2RANA 1AEIA 1BCWA 1HM6A 2H0MA 1YCNA 2H0KA 2HYWA 1BC3A 1N41A 1G5NA 2Q4CA 1W7BA 2XO3A 2H0LA 1I4AA 2XO2A 2HYUA 1ANWA 1A8AA 1AXNA 1BCYA 1AVCA 4X9PA 1HVFA 1W45A 1BC1A 1HVDA 1N44A 2IE7A 2ZHJA 1ANNA 1N00A 1DM5A 1M9IA 4HREA 4MDVA 1BCZA 1YJ0A 2II2A 1ALAA 1AIIA 4MDUA 4EVFA 1W3WA 4EVHA 1BC0A 1MCXA 3BRXA 1A8BA 1HVEA 1DK5A 1YIIA 1ANXA 1SAVA 2ZOCA 1HAKA 1AOWA 1XJLA
chains in the Genus database with same CATH superfamily
3AO0A 2HSNA 4Z21A 2IICA 2IE6A 4C7PA 1BCWA 1HM6A 2H0MA 3ABSA 2R09A 2VXGA 1ANWA 4D7RA 1BCYA 4FQ0C 1XT0B 1XSZA 3L8NA 4HREA 4Q2SA 4C0AA 1BC0A 1MCXA 3ABRA 1YIIA 1ANXA 1LKVX 1AOWA 1S9DE 2HYWA 1N41A 1W7BA 1I4AA 2XO2A 2HYUA 3HJLA 1R8QE 1R8SE 4X9PA 1HVFA 1N44A 3TW5A 1DM5A 1M9IA 4EVFA 1AIIA 4MDUA 1W3WA 2QEZA 3USWA 3AJCA 1SAVA 1UPTB 1BO9A 2OY9A 1BC9A 1N42A 1RE0B 1C1KA 1HVGA 4D7QA 2ZHIA 4JMOA 1PBVA 1BC3A 1R4AE 4KMUX 2Q4CA 4FHRB 2K6XA 4A4PA 2XO3A 3ANYA 1AXNA 1KU1A 3SOHB 1BCZA 1YJ0A 1ALAA 3ABOA 3SWVA 3BRXA 1HVEA 1DK5A 1HAKA 1XJLA 3USYA 2HYVA 4KN7X 1AVRA 1QC7A 3ABQA 4JMIA 4JXHA 1AVHA 1R8ME 2RANA 1AEIA 1YCNA 2H0KA 4KN4X 1G5NA 2H0LA 3LTLA 1A8AA 1AVCA 4JK1X 1W45A 2IE7A 1BC1A 1HVDA 4OIYA 2ZHJA 1ANNA 1N00A 4MDVA 2II2A 4EVHA 4L5MA 4JWLA 1A8BA 2R0DA 2ZOCA 1Q8DA 1YGMA
chains in the Genus database with same CATH topology
2HYVA 1AVRA 1N42A 1HVGA 1AVHA 2ZHIA 2IICA 1BO9A 2IE6A 2RANA 1AEIA 1BCWA 1HM6A 2H0MA 1YCNA 2H0KA 2HYWA 1BC3A 1N41A 1G5NA 2Q4CA 1W7BA 2XO3A 2H0LA 1I4AA 2XO2A 2HYUA 1ANWA 1A8AA 1AXNA 1BCYA 1AVCA 4X9PA 1HVFA 1W45A 1BC1A 1HVDA 1N44A 2IE7A 2ZHJA 1ANNA 1N00A 1DM5A 1M9IA 4HREA 4MDVA 1BCZA 1YJ0A 2II2A 1ALAA 1AIIA 4MDUA 4EVFA 1W3WA 4EVHA 1BC0A 1MCXA 3BRXA 1A8BA 1HVEA 1DK5A 1YIIA 1ANXA 1SAVA 2ZOCA 1HAKA 1AOWA 1XJLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HYV A;  1AVR A;  1N42 A;  1HVG A;  1AVH A;  2ZHI A;  2IIC A;  1BO9 A;  2IE6 A;  2RAN A;  1AEI A;  1BCW A;  1HM6 A;  2H0M A;  1YCN A;  2H0K A;  2HYW A;  1BC3 A;  1N41 A;  1G5N A;  2Q4C A;  1W7B A;  2XO3 A;  2H0L A;  1I4A A;  2XO2 A;  2HYU A;  1ANW A;  1A8A A;  1AXN A;  1BCY A;  1AVC A;  4X9P A;  1HVF A;  1W45 A;  1BC1 A;  1HVD A;  1N44 A;  2IE7 A;  2ZHJ A;  1ANN A;  1N00 A;  1DM5 A;  1M9I A;  4HRE A;  4MDV A;  1BCZ A;  1YJ0 A;  2II2 A;  1ALA A;  1AII A;  4MDU A;  4EVF A;  1W3W A;  4EVH A;  1BC0 A;  1MCX A;  3BRX A;  1A8B A;  1HVE A;  1DK5 A;  1YII A;  1ANX A;  1SAV A;  2ZOC A;  1HAK A;  1AOW A;  1XJL A; 
#chains in the Genus database with same CATH topology
 3AO0 A;  2HSN A;  4Z21 A;  2IIC A;  2IE6 A;  4C7P A;  1BCW A;  1HM6 A;  2H0M A;  3ABS A;  2R09 A;  2VXG A;  1ANW A;  4D7R A;  1BCY A;  4FQ0 C;  1XT0 B;  1XSZ A;  3L8N A;  4HRE A;  4Q2S A;  4C0A A;  1BC0 A;  1MCX A;  3ABR A;  1YII A;  1ANX A;  1LKV X;  1AOW A;  1S9D E;  2HYW A;  1N41 A;  1W7B A;  1I4A A;  2XO2 A;  2HYU A;  3HJL A;  1R8Q E;  1R8S E;  4X9P A;  1HVF A;  1N44 A;  3TW5 A;  1DM5 A;  1M9I A;  4EVF A;  1AII A;  4MDU A;  1W3W A;  2QEZ A;  3USW A;  3AJC A;  1SAV A;  1UPT B;  1BO9 A;  2OY9 A;  1BC9 A;  1N42 A;  1RE0 B;  1C1K A;  1HVG A;  4D7Q A;  2ZHI A;  4JMO A;  1PBV A;  1BC3 A;  1R4A E;  4KMU X;  2Q4C A;  4FHR B;  2K6X A;  4A4P A;  2XO3 A;  3ANY A;  1AXN A;  1KU1 A;  3SOH B;  1BCZ A;  1YJ0 A;  1ALA A;  3ABO A;  3SWV A;  3BRX A;  1HVE A;  1DK5 A;  1HAK A;  1XJL A;  3USY A;  2HYV A;  4KN7 X;  1AVR A;  1QC7 A;  3ABQ A;  4JMI A;  4JXH A;  1AVH A;  1R8M E;  2RAN A;  1AEI A;  1YCN A;  2H0K A;  4KN4 X;  1G5N A;  2H0L A;  3LTL A;  1A8A A;  1AVC A;  4JK1 X;  1W45 A;  2IE7 A;  1BC1 A;  1HVD A;  4OIY A;  2ZHJ A;  1ANN A;  1N00 A;  4MDV A;  2II2 A;  4EVH A;  4L5M A;  4JWL A;  1A8B A;  2R0D A;  2ZOC A;  1Q8D A;  1YGM A; 
#chains in the Genus database with same CATH homology
 2HYV A;  1AVR A;  1N42 A;  1HVG A;  1AVH A;  2ZHI A;  2IIC A;  1BO9 A;  2IE6 A;  2RAN A;  1AEI A;  1BCW A;  1HM6 A;  2H0M A;  1YCN A;  2H0K A;  2HYW A;  1BC3 A;  1N41 A;  1G5N A;  2Q4C A;  1W7B A;  2XO3 A;  2H0L A;  1I4A A;  2XO2 A;  2HYU A;  1ANW A;  1A8A A;  1AXN A;  1BCY A;  1AVC A;  4X9P A;  1HVF A;  1W45 A;  1BC1 A;  1HVD A;  1N44 A;  2IE7 A;  2ZHJ A;  1ANN A;  1N00 A;  1DM5 A;  1M9I A;  4HRE A;  4MDV A;  1BCZ A;  1YJ0 A;  2II2 A;  1ALA A;  1AII A;  4MDU A;  4EVF A;  1W3W A;  4EVH A;  1BC0 A;  1MCX A;  3BRX A;  1A8B A;  1HVE A;  1DK5 A;  1YII A;  1ANX A;  1SAV A;  2ZOC A;  1HAK A;  1AOW A;  1XJL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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