2CRKA

Muscle creatine kinase
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
374
structure length
365
Chain Sequence
NKYKLNYKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDDLDPHYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTSVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
publication title Crystal structure of rabbit muscle creatine kinase.
pubmed doi rcsb
molecule keywords PROTEIN (CREATINE KINASE)
total genus 117
structure length 365
sequence length 374
ec nomenclature ec 2.7.3.2: Creatine kinase.
pdb deposition date 1998-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 2crkA01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 2crkA02
2WGSA 4LNKA 3DREA 3L2DA 1P52A 4S0RA 1P50A 5J99A 4XYCA 3ZXRA 4S17A 1QK1A 1BG0A 1U6RA 4GVZA 4LNIA 4Z9MA 1HTOA 4LNFA 1SD0A 4Q2RA 4AM1A 1VRPA 4RF8A 1LGRA 2LGSA 3NG0A 4BG4A 4RF7A 3JU6A 5J9AA 4RF6A 3M10A 4LNOA 4LNNA 1FPYA 4BHLA 3JPZA 3JQ3A 3L2EA 4BG4B 1M15A 1QH4A 3JU5A 2BVCA 4GW2A 1I0EA 1G0WA 2WHIA 1CRKA 3DRBA 2GLSA 4GW0A 1HTQA 4RF9A 4ACFA 3ZXVA 1RL9A 2J1QA 1F1HA 4HPPA 3L2EB 1F52A 3B6RA 4GVYA 2CRKA
chains in the Genus database with same CATH superfamily
4LNKA 4S0RA 1P50A 5J99A 3IG5A 4LNIA 1HTOA 1R8GA 2OJWA 4LNFA 4AM1A 3JU6A 1VA6A 2UU7A 3JPZA 3L2EA 2D32A 1M15A 2BVCA 1CRKA 3ZXVA 2J1QA 3L2EB 4BAXA 2CRKA 3DREA 3L2DA 1P52A 4Z9MA 2D33A 4BG4A 5J9AA 4LNOA 3JQ3A 4BG4B 3LVWA 1QH4A 4GW2A 1G0WA 2GLSA 2D3CA 2GWDA 1RL9A 1F1HA 4HPPA 2GWCA 2WGSA 4S17A 1QK1A 1U6RA 4GVZA 3LVVA 4RF8A 1LGRA 2LGSA 4RF7A 3LN7A 1FPYA 4BHLA 3NZTA 3JU5A 1I0EA 1V4GA 3IG8A 4GW0A 4ACFA 3B6RA 3NG0A 2D3AA 3FKYA 4XYCA 3ZXRA 1BG0A 1SD0A 4Q2RA 1VRPA 2QC8A 4RF6A 3M10A 2D3BA 4LNNA 3DRBA 1HTQA 4RF9A 3LN6A 1F52A 4GVYA 2WHIA 1TT4A
chains in the Genus database with same CATH topology
2WGSA 4LNKA 3DREA 3L2DA 1P52A 4S0RA 1P50A 5J99A 4XYCA 3ZXRA 4S17A 1QK1A 1BG0A 1U6RA 4GVZA 4LNIA 4Z9MA 1HTOA 4LNFA 1SD0A 4Q2RA 4AM1A 1VRPA 4RF8A 1LGRA 2LGSA 3NG0A 4BG4A 4RF7A 3JU6A 5J9AA 4RF6A 3M10A 4LNOA 4LNNA 1FPYA 4BHLA 3JPZA 3JQ3A 3L2EA 4BG4B 1M15A 1QH4A 3JU5A 2BVCA 4GW2A 1I0EA 1G0WA 2WHIA 1CRKA 3DRBA 2GLSA 4GW0A 1HTQA 4RF9A 4ACFA 3ZXVA 1RL9A 2J1QA 1F1HA 4HPPA 3L2EB 1F52A 3B6RA 4GVYA 2CRKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WGS A;  4LNK A;  3DRE A;  3L2D A;  1P52 A;  4S0R A;  1P50 A;  5J99 A;  4XYC A;  3ZXR A;  4S17 A;  1QK1 A;  1BG0 A;  1U6R A;  4GVZ A;  4LNI A;  4Z9M A;  1HTO A;  4LNF A;  1SD0 A;  4Q2R A;  4AM1 A;  1VRP A;  4RF8 A;  1LGR A;  2LGS A;  3NG0 A;  4BG4 A;  4RF7 A;  3JU6 A;  5J9A A;  4RF6 A;  3M10 A;  4LNO A;  4LNN A;  1FPY A;  4BHL A;  3JPZ A;  3JQ3 A;  3L2E A;  4BG4 B;  1M15 A;  1QH4 A;  3JU5 A;  2BVC A;  4GW2 A;  1I0E A;  1G0W A;  2WHI A;  1CRK A;  3DRB A;  2GLS A;  4GW0 A;  1HTQ A;  4RF9 A;  4ACF A;  3ZXV A;  1RL9 A;  2J1Q A;  1F1H A;  4HPP A;  3L2E B;  1F52 A;  3B6R A;  4GVY A;  2CRK A; 
#chains in the Genus database with same CATH topology
 4LNK A;  4S0R A;  1P50 A;  5J99 A;  3IG5 A;  4LNI A;  1HTO A;  1R8G A;  2OJW A;  4LNF A;  4AM1 A;  3JU6 A;  1VA6 A;  2UU7 A;  3JPZ A;  3L2E A;  2D32 A;  1M15 A;  2BVC A;  1CRK A;  3ZXV A;  2J1Q A;  3L2E B;  4BAX A;  2CRK A;  3DRE A;  3L2D A;  1P52 A;  4Z9M A;  2D33 A;  4BG4 A;  5J9A A;  4LNO A;  3JQ3 A;  4BG4 B;  3LVW A;  1QH4 A;  4GW2 A;  1G0W A;  2GLS A;  2D3C A;  2GWD A;  1RL9 A;  1F1H A;  4HPP A;  2GWC A;  2WGS A;  4S17 A;  1QK1 A;  1U6R A;  4GVZ A;  3LVV A;  4RF8 A;  1LGR A;  2LGS A;  4RF7 A;  3LN7 A;  1FPY A;  4BHL A;  3NZT A;  3JU5 A;  1I0E A;  1V4G A;  3IG8 A;  4GW0 A;  4ACF A;  3B6R A;  3NG0 A;  2D3A A;  3FKY A;  4XYC A;  3ZXR A;  1BG0 A;  1SD0 A;  4Q2R A;  1VRP A;  2QC8 A;  4RF6 A;  3M10 A;  2D3B A;  4LNN A;  3DRB A;  1HTQ A;  4RF9 A;  3LN6 A;  1F52 A;  4GVY A;  2WHI A;  1TT4 A; 
#chains in the Genus database with same CATH homology
 2WGS A;  4LNK A;  3DRE A;  3L2D A;  1P52 A;  4S0R A;  1P50 A;  5J99 A;  4XYC A;  3ZXR A;  4S17 A;  1QK1 A;  1BG0 A;  1U6R A;  4GVZ A;  4LNI A;  4Z9M A;  1HTO A;  4LNF A;  1SD0 A;  4Q2R A;  4AM1 A;  1VRP A;  4RF8 A;  1LGR A;  2LGS A;  3NG0 A;  4BG4 A;  4RF7 A;  3JU6 A;  5J9A A;  4RF6 A;  3M10 A;  4LNO A;  4LNN A;  1FPY A;  4BHL A;  3JPZ A;  3JQ3 A;  3L2E A;  4BG4 B;  1M15 A;  1QH4 A;  3JU5 A;  2BVC A;  4GW2 A;  1I0E A;  1G0W A;  2WHI A;  1CRK A;  3DRB A;  2GLS A;  4GW0 A;  1HTQ A;  4RF9 A;  4ACF A;  3ZXV A;  1RL9 A;  2J1Q A;  1F1H A;  4HPP A;  3L2E B;  1F52 A;  3B6R A;  4GVY A;  2CRK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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