2CRKA

Muscle creatine kinase
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
374
structure length
365
Chain Sequence
NKYKLNYKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDDLDPHYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTSVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rabbit muscle creatine kinase.
pubmed doi rcsb
molecule tags Transferase
molecule keywords PROTEIN (CREATINE KINASE)
total genus 117
structure length 365
sequence length 374
ec nomenclature ec 2.7.3.2: Creatine kinase.
pdb deposition date 1998-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 2crkA01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 2crkA02
4S17A 1SD0A 3ZXVA 4LNFA 3M10A 3JU5A 1F1HA 1FPYA 4ACFA 4GVYA 1CRKA 1RL9A 4RF9A 4LNOA 1U6RA 4Z9MA 1HTOA 2BVCA 4Q2RA 1LGRA 2LGSA 4HPPA 2J1QA 4S0RA 1P50A 3JQ3A 1P52A 4RF7A 1M15A 1F52A 3DRBA 3DREA 1VRPA 4GW0A 4XYCA 4GW2A 1BG0A 3L2DA 3ZXRA 4LNNA 4BG4B 3JU6A 1QK1A 1HTQA 4BHLA 3JPZA 4AM1A 3L2EB 4RF8A 2CRKA 4LNIA 1QH4A 3B6RA 1I0EA 5J9AA 2WGSA 2GLSA 4LNKA 4BG4A 1G0WA 4GVZA 4RF6A 5J99A 2WHIA 3L2EA 3NG0A
chains in the Genus database with same CATH superfamily
4ACFA 4GVYA 1U6RA 4HPPA 4Q2RA 2LGSA 2J1QA 4S0RA 1P52A 3DREA 2OJWA 4BG4B 1R8GA 4BHLA 2D33A 3L2EB 2CRKA 4LNKA 1G0WA 3ZXVA 3FKYA 1CRKA 4RF9A 2BVCA 4BAXA 1V4GA 1F52A 1VRPA 3L2DA 3JU6A 2D32A 4AM1A 2GLSA 2UU7A 3LVVA 4RF6A 2WHIA 2GWDA 4S17A 1SD0A 3LN6A 3M10A 3JU5A 4LNOA 1VA6A 1HTOA 2D3AA 3JQ3A 4RF7A 1M15A 3DRBA 4XYCA 3ZXRA 4GW2A 3IG5A 1QK1A 3B6RA 1I0EA 5J9AA 1TT4A 2QC8A 3NZTA 3NG0A 2D3BA 4LNFA 1F1HA 1FPYA 3LN7A 1RL9A 4Z9MA 1LGRA 1P50A 4GW0A 1BG0A 4LNNA 1HTQA 3JPZA 3LVWA 4RF8A 4LNIA 1QH4A 2WGSA 4BG4A 4GVZA 2D3CA 5J99A 2GWCA 3L2EA 3IG8A
chains in the Genus database with same CATH topology
4S17A 1SD0A 3ZXVA 4LNFA 3M10A 3JU5A 1F1HA 1FPYA 4ACFA 4GVYA 1CRKA 1RL9A 4RF9A 4LNOA 1U6RA 4Z9MA 1HTOA 2BVCA 4Q2RA 1LGRA 2LGSA 4HPPA 2J1QA 4S0RA 1P50A 3JQ3A 1P52A 4RF7A 1M15A 1F52A 3DRBA 3DREA 1VRPA 4GW0A 4XYCA 4GW2A 1BG0A 3L2DA 3ZXRA 4LNNA 4BG4B 3JU6A 1QK1A 1HTQA 4BHLA 3JPZA 4AM1A 3L2EB 4RF8A 2CRKA 4LNIA 1QH4A 3B6RA 1I0EA 5J9AA 2WGSA 2GLSA 4LNKA 4BG4A 1G0WA 4GVZA 4RF6A 5J99A 2WHIA 3L2EA 3NG0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4S17 A;  1SD0 A;  3ZXV A;  4LNF A;  3M10 A;  3JU5 A;  1F1H A;  1FPY A;  4ACF A;  4GVY A;  1CRK A;  1RL9 A;  4RF9 A;  4LNO A;  1U6R A;  4Z9M A;  1HTO A;  2BVC A;  4Q2R A;  1LGR A;  2LGS A;  4HPP A;  2J1Q A;  4S0R A;  1P50 A;  3JQ3 A;  1P52 A;  4RF7 A;  1M15 A;  1F52 A;  3DRB A;  3DRE A;  1VRP A;  4GW0 A;  4XYC A;  4GW2 A;  1BG0 A;  3L2D A;  3ZXR A;  4LNN A;  4BG4 B;  3JU6 A;  1QK1 A;  1HTQ A;  4BHL A;  3JPZ A;  4AM1 A;  3L2E B;  4RF8 A;  2CRK A;  4LNI A;  1QH4 A;  3B6R A;  1I0E A;  5J9A A;  2WGS A;  2GLS A;  4LNK A;  4BG4 A;  1G0W A;  4GVZ A;  4RF6 A;  5J99 A;  2WHI A;  3L2E A;  3NG0 A; 
#chains in the Genus database with same CATH topology
 4ACF A;  4GVY A;  1U6R A;  4HPP A;  4Q2R A;  2LGS A;  2J1Q A;  4S0R A;  1P52 A;  3DRE A;  2OJW A;  4BG4 B;  1R8G A;  4BHL A;  2D33 A;  3L2E B;  2CRK A;  4LNK A;  1G0W A;  3ZXV A;  3FKY A;  1CRK A;  4RF9 A;  2BVC A;  4BAX A;  1V4G A;  1F52 A;  1VRP A;  3L2D A;  3JU6 A;  2D32 A;  4AM1 A;  2GLS A;  2UU7 A;  3LVV A;  4RF6 A;  2WHI A;  2GWD A;  4S17 A;  1SD0 A;  3LN6 A;  3M10 A;  3JU5 A;  4LNO A;  1VA6 A;  1HTO A;  2D3A A;  3JQ3 A;  4RF7 A;  1M15 A;  3DRB A;  4XYC A;  3ZXR A;  4GW2 A;  3IG5 A;  1QK1 A;  3B6R A;  1I0E A;  5J9A A;  1TT4 A;  2QC8 A;  3NZT A;  3NG0 A;  2D3B A;  4LNF A;  1F1H A;  1FPY A;  3LN7 A;  1RL9 A;  4Z9M A;  1LGR A;  1P50 A;  4GW0 A;  1BG0 A;  4LNN A;  1HTQ A;  3JPZ A;  3LVW A;  4RF8 A;  4LNI A;  1QH4 A;  2WGS A;  4BG4 A;  4GVZ A;  2D3C A;  5J99 A;  2GWC A;  3L2E A;  3IG8 A; 
#chains in the Genus database with same CATH homology
 4S17 A;  1SD0 A;  3ZXV A;  4LNF A;  3M10 A;  3JU5 A;  1F1H A;  1FPY A;  4ACF A;  4GVY A;  1CRK A;  1RL9 A;  4RF9 A;  4LNO A;  1U6R A;  4Z9M A;  1HTO A;  2BVC A;  4Q2R A;  1LGR A;  2LGS A;  4HPP A;  2J1Q A;  4S0R A;  1P50 A;  3JQ3 A;  1P52 A;  4RF7 A;  1M15 A;  1F52 A;  3DRB A;  3DRE A;  1VRP A;  4GW0 A;  4XYC A;  4GW2 A;  1BG0 A;  3L2D A;  3ZXR A;  4LNN A;  4BG4 B;  3JU6 A;  1QK1 A;  1HTQ A;  4BHL A;  3JPZ A;  4AM1 A;  3L2E B;  4RF8 A;  2CRK A;  4LNI A;  1QH4 A;  3B6R A;  1I0E A;  5J9A A;  2WGS A;  2GLS A;  4LNK A;  4BG4 A;  1G0W A;  4GVZ A;  4RF6 A;  5J99 A;  2WHI A;  3L2E A;  3NG0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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