2GWCA

Crystal structure of plant glutamate cysteine ligase in complex with a transition state analogue
Total Genus 139
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
438
structure length
438
Chain Sequence
ATEPLTREDLIAYLASGCKSKEKWRIGTEHEKFGFEVNTLRPMKYDQIAELLNSIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGMGFQPKWRREDIPTMPKGRYDIMRNYMPKVGSLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYALDVPMYFAYRNGKYVDCTGMTFRQFLAGKLPCLPGELPTYNDWENHLTTIFPEVRLKRYMEMRGADGGPWRRLCALPAFWVGLLYDEDVLQSVLDLTADWTPAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEVGFLNAVTEVVRTGVTPAENLLEMYNGEWGQSVDPVFQELLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis for the redox control of plant glutamate cysteine ligase.
pubmed doi rcsb
molecule tags Ligase
source organism Brassica juncea
molecule keywords Glutamate cysteine ligase
total genus 139
structure length 438
sequence length 438
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04107 GCS2 Glutamate-cysteine ligase family 2(GCS2)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2gwcA00
2D32A 1R8GA 2GWCA 3LN6A 1VA6A 1TT4A 1V4GA 2GWDA 3LN7A 3NZTA 2D33A
chains in the Genus database with same CATH superfamily
3L2DA 4GW2A 2D3BA 3M10A 4BG4B 3JQ3A 1VRPA 1I0EA 4RF9A 3LN7A 4AM1A 1HTQA 2LGSA 4Q2RA 4RF6A 4BG4A 1QK1A 2GWDA 3JU5A 4RF7A 4ACFA 3IG8A 4Z9MA 2WHIA 3DRBA 2GWCA 4S17A 2D3AA 1TT4A 1V4GA 3ZXRA 2J1QA 1RL9A 1F1HA 3FKYA 1R8GA 1U6RA 4BHLA 4LNFA 3NZTA 3IG5A 2UU7A 3JU6A 3LN6A 5J9AA 3B6RA 2D32A 1VA6A 1BG0A 1FPYA 2CRKA 4LNKA 4GVYA 2D3CA 1QH4A 4GW0A 1P52A 2BVCA 1P50A 4LNOA 1M15A 4BAXA 4S0RA 4GVZA 3LVWA 3NG0A 1CRKA 3L2EB 4XYCA 3LVVA 5J99A 1G0WA 3JPZA 2D33A 3L2EA 2OJWA 2QC8A 2GLSA 4RF8A 1LGRA 1HTOA 4LNIA 3DREA 1F52A 1SD0A 4LNNA 2WGSA 3ZXVA 4HPPA
chains in the Genus database with same CATH topology
2GWCA 2D3AA 1TT4A 1V4GA 2D3BA 2D3CA 2D33A 2OJWA 3FKYA 1R8GA 2QC8A 3NZTA 3LN7A 3IG5A 4BAXA 2UU7A 3LN6A 2GWDA 3LVWA 2D32A 1VA6A 3IG8A 3LVVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D32 A;  1R8G A;  2GWC A;  3LN6 A;  1VA6 A;  1TT4 A;  1V4G A;  2GWD A;  3LN7 A;  3NZT A;  2D33 A; 
#chains in the Genus database with same CATH topology
 3L2D A;  4GW2 A;  2D3B A;  3M10 A;  4BG4 B;  3JQ3 A;  1VRP A;  1I0E A;  4RF9 A;  3LN7 A;  4AM1 A;  1HTQ A;  2LGS A;  4Q2R A;  4RF6 A;  4BG4 A;  1QK1 A;  2GWD A;  3JU5 A;  4RF7 A;  4ACF A;  3IG8 A;  4Z9M A;  2WHI A;  3DRB A;  2GWC A;  4S17 A;  2D3A A;  1TT4 A;  1V4G A;  3ZXR A;  2J1Q A;  1RL9 A;  1F1H A;  3FKY A;  1R8G A;  1U6R A;  4BHL A;  4LNF A;  3NZT A;  3IG5 A;  2UU7 A;  3JU6 A;  3LN6 A;  5J9A A;  3B6R A;  2D32 A;  1VA6 A;  1BG0 A;  1FPY A;  2CRK A;  4LNK A;  4GVY A;  2D3C A;  1QH4 A;  4GW0 A;  1P52 A;  2BVC A;  1P50 A;  4LNO A;  1M15 A;  4BAX A;  4S0R A;  4GVZ A;  3LVW A;  3NG0 A;  1CRK A;  3L2E B;  4XYC A;  3LVV A;  5J99 A;  1G0W A;  3JPZ A;  2D33 A;  3L2E A;  2OJW A;  2QC8 A;  2GLS A;  4RF8 A;  1LGR A;  1HTO A;  4LNI A;  3DRE A;  1F52 A;  1SD0 A;  4LNN A;  2WGS A;  3ZXV A;  4HPP A; 
#chains in the Genus database with same CATH homology
 2GWC A;  2D3A A;  1TT4 A;  1V4G A;  2D3B A;  2D3C A;  2D33 A;  2OJW A;  3FKY A;  1R8G A;  2QC8 A;  3NZT A;  3LN7 A;  3IG5 A;  4BAX A;  2UU7 A;  3LN6 A;  2GWD A;  3LVW A;  2D32 A;  1VA6 A;  3IG8 A;  3LVV A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...