2GWDA

Crystal structure of plant glutamate cysteine ligase in complex with mg2+ and l-glutamate
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
436
structure length
436
Chain Sequence
EPLTREDLIAYLASGCKSKEKWRIGTEHEKFGFEVNTLRPMKYDQIAELLNSIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGMGFQPKWRREDIPTMPKGRYDIMRNYMPKVGSLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYALDVPMYFAYRNGKYVDCTGMTFRQFLAGKLPCLPGELPTYNDWENHLTTIFPEVRLKRYMEMRGADGGPWRRLCALPAFWVGLLYDEDVLQSVLDLTADWTPAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEVGFLNAVTEVVRTGVTPAENLLEMYNGEWGQSVDPVFQELLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the redox control of plant glutamate cysteine ligase.
pubmed doi rcsb
molecule tags Ligase
source organism Brassica juncea
molecule keywords Glutamate cysteine ligase
total genus 159
structure length 436
sequence length 436
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04107 GCS2 Glutamate-cysteine ligase family 2(GCS2)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2gwdA00
2GWCA 3NZTA 1TT4A 1R8GA 1VA6A 1V4GA 2GWDA 2D33A 3LN7A 2D32A 3LN6A
chains in the Genus database with same CATH superfamily
1FPYA 3L2EB 4RF7A 3LVWA 4LNFA 1V4GA 4S17A 4GVYA 1HTOA 3IG8A 1TT4A 4LNNA 3JU5A 1HTQA 2UU7A 2CRKA 1SD0A 2QC8A 2D3CA 4GW0A 1RL9A 4ACFA 4Q2RA 3DREA 4S0RA 1G0WA 3L2DA 3JU6A 3ZXRA 4LNKA 1BG0A 4LNIA 2BVCA 4BG4A 3LN6A 2WHIA 4GW2A 4BHLA 3DRBA 3LN7A 3JQ3A 4BG4B 5J9AA 2D3AA 2GLSA 4RF6A 2J1QA 1I0EA 3NG0A 1R8GA 4RF8A 2GWDA 4HPPA 3M10A 4BAXA 4LNOA 1P52A 2D32A 4GVZA 2D3BA 1CRKA 4AM1A 3B6RA 3LVVA 4RF9A 2GWCA 3IG5A 3FKYA 2LGSA 4XYCA 1F52A 2WGSA 1VA6A 1QK1A 2OJWA 1VRPA 1QH4A 1P50A 1LGRA 1F1HA 5J99A 1U6RA 3NZTA 3ZXVA 4Z9MA 3L2EA 2D33A 1M15A 3JPZA
chains in the Genus database with same CATH topology
1R8GA 3LVWA 1VA6A 1V4GA 2GWDA 2OJWA 3IG8A 1TT4A 4BAXA 2UU7A 2D32A 2QC8A 2D3BA 2D3CA 3LN6A 3NZTA 2D33A 3LN7A 3LVVA 2GWCA 3IG5A 2D3AA 3FKYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GWC A;  3NZT A;  1TT4 A;  1R8G A;  1VA6 A;  1V4G A;  2GWD A;  2D33 A;  3LN7 A;  2D32 A;  3LN6 A; 
#chains in the Genus database with same CATH topology
 1FPY A;  3L2E B;  4RF7 A;  3LVW A;  4LNF A;  1V4G A;  4S17 A;  4GVY A;  1HTO A;  3IG8 A;  1TT4 A;  4LNN A;  3JU5 A;  1HTQ A;  2UU7 A;  2CRK A;  1SD0 A;  2QC8 A;  2D3C A;  4GW0 A;  1RL9 A;  4ACF A;  4Q2R A;  3DRE A;  4S0R A;  1G0W A;  3L2D A;  3JU6 A;  3ZXR A;  4LNK A;  1BG0 A;  4LNI A;  2BVC A;  4BG4 A;  3LN6 A;  2WHI A;  4GW2 A;  4BHL A;  3DRB A;  3LN7 A;  3JQ3 A;  4BG4 B;  5J9A A;  2D3A A;  2GLS A;  4RF6 A;  2J1Q A;  1I0E A;  3NG0 A;  1R8G A;  4RF8 A;  2GWD A;  4HPP A;  3M10 A;  4BAX A;  4LNO A;  1P52 A;  2D32 A;  4GVZ A;  2D3B A;  1CRK A;  4AM1 A;  3B6R A;  3LVV A;  4RF9 A;  2GWC A;  3IG5 A;  3FKY A;  2LGS A;  4XYC A;  1F52 A;  2WGS A;  1VA6 A;  1QK1 A;  2OJW A;  1VRP A;  1QH4 A;  1P50 A;  1LGR A;  1F1H A;  5J99 A;  1U6R A;  3NZT A;  3ZXV A;  4Z9M A;  3L2E A;  2D33 A;  1M15 A;  3JPZ A; 
#chains in the Genus database with same CATH homology
 1R8G A;  3LVW A;  1VA6 A;  1V4G A;  2GWD A;  2OJW A;  3IG8 A;  1TT4 A;  4BAX A;  2UU7 A;  2D32 A;  2QC8 A;  2D3B A;  2D3C A;  3LN6 A;  3NZT A;  2D33 A;  3LN7 A;  3LVV A;  2GWC A;  3IG5 A;  2D3A A;  3FKY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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