2H0LA

Crystal structure of a mutant of rat annexin a5
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
318
structure length
316
Chain Sequence
ALRGTVTDFSGFDGEADAEVLRKAMEGLGTDEDSILNLLTARSNAQRQQIAEEFETLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQEMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEEFITILGTRSVSHLRRVFDKYMTISGFQIEETIDTSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLSGGEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
source organism Rattus norvegicus
publication title Identification of the Residues Involved in the Formation of Annexin V Trimers within 2D and 3D Crystals
rcsb
molecule keywords Annexin A5
total genus 121
structure length 316
sequence length 318
ec nomenclature
pdb deposition date 2006-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2h0lA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2h0lA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2h0lA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2h0lA03
2ZHIA 1ANXA 3BRXA 1BC0A 1ANWA 1HVEA 1AXNA 1BC3A 1I4AA 1AVCA 1HAKA 2HYUA 1N00A 2IE6A 2H0MA 4HREA 1BCYA 1AVHA 1M9IA 4MDUA 1ALAA 1HVDA 1W7BA 1A8AA 1BO9A 2RANA 1G5NA 1AOWA 1N41A 1YJ0A 4EVHA 4MDVA 4EVFA 1W45A 1A8BA 1W3WA 1AEIA 2XO2A 1DK5A 2HYWA 2H0KA 2XO3A 1N42A 1DM5A 1ANNA 1N44A 2IICA 1YIIA 2H0LA 2ZHJA 4X9PA 1HVGA 1BC1A 1BCWA 1AVRA 1HVFA 2ZOCA 2IE7A 1SAVA 2II2A 1AIIA 1XJLA 2Q4CA 2HYVA 1BCZA 1HM6A 1YCNA 1MCXA
chains in the Genus database with same CATH superfamily
4A4PA 4JWLA 3SOHB 1KU1A 1ANXA 2R09A 1R4AE 1ANWA 1AXNA 1AVCA 1HAKA 2HYUA 4MDUA 3USWA 1AVHA 1W7BA 1BO9A 3TW5A 2VXGA 4EVFA 1Q8DA 1W45A 2HYWA 1C1KA 2H0KA 2XO3A 4JMIA 2HSNA 1ANNA 1N44A 2ZHJA 1XSZA 1BC1A 2ZOCA 3ABOA 1AIIA 2HYVA 1BCZA 1MCXA 4JXHA 2ZHIA 3BRXA 1R8SE 1HVEA 1BC3A 1I4AA 2QEZA 3ABRA 1N00A 1BCYA 1M9IA 1ALAA 1HVDA 1BC9A 1R8ME 2R0DA 4EVHA 4KN4X 1W3WA 3ANYA 4L5MA 4KMUX 1AVRA 2II2A 1LKVX 1HM6A 1YCNA 1UPTB 1BC0A 3USYA 4Z21A 1PBVA 3HJLA 4C0AA 4Q2SA 4FQ0C 1A8BA 1AEIA 2XO2A 3AO0A 1N42A 1RE0B 1DM5A 2OY9A 2H0LA 4C7PA 1HVGA 1QC7A 1BCWA 1HVFA 4D7QA 2IE7A 1S9DE 4OIYA 4JMOA 4JK1X 1R8QE 1XJLA 2Q4CA 4MDVA 1XT0B 3SWVA 4KN7X 2IE6A 2H0MA 4HREA 1A8AA 2RANA 1G5NA 1AOWA 1N41A 1YJ0A 3LTLA 1DK5A 3L8NA 1YGMA 3ABQA 2K6XA 4FHRB 2IICA 1YIIA 4X9PA 1SAVA 3ABSA 3AJCA 4D7RA
chains in the Genus database with same CATH topology
2ZHIA 1ANXA 3BRXA 1BC0A 1ANWA 1HVEA 1AXNA 1BC3A 1I4AA 1AVCA 1HAKA 2HYUA 1N00A 2IE6A 2H0MA 4HREA 1BCYA 1AVHA 1M9IA 4MDUA 1ALAA 1HVDA 1W7BA 1A8AA 1BO9A 2RANA 1G5NA 1AOWA 1N41A 1YJ0A 4EVHA 4MDVA 4EVFA 1W45A 1A8BA 1W3WA 1AEIA 2XO2A 1DK5A 2HYWA 2H0KA 2XO3A 1N42A 1DM5A 1ANNA 1N44A 2IICA 1YIIA 2H0LA 2ZHJA 4X9PA 1HVGA 1BC1A 1BCWA 1AVRA 1HVFA 2ZOCA 2IE7A 1SAVA 2II2A 1AIIA 1XJLA 2Q4CA 2HYVA 1BCZA 1HM6A 1YCNA 1MCXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZHI A;  1ANX A;  3BRX A;  1BC0 A;  1ANW A;  1HVE A;  1AXN A;  1BC3 A;  1I4A A;  1AVC A;  1HAK A;  2HYU A;  1N00 A;  2IE6 A;  2H0M A;  4HRE A;  1BCY A;  1AVH A;  1M9I A;  4MDU A;  1ALA A;  1HVD A;  1W7B A;  1A8A A;  1BO9 A;  2RAN A;  1G5N A;  1AOW A;  1N41 A;  1YJ0 A;  4EVH A;  4MDV A;  4EVF A;  1W45 A;  1A8B A;  1W3W A;  1AEI A;  2XO2 A;  1DK5 A;  2HYW A;  2H0K A;  2XO3 A;  1N42 A;  1DM5 A;  1ANN A;  1N44 A;  2IIC A;  1YII A;  2H0L A;  2ZHJ A;  4X9P A;  1HVG A;  1BC1 A;  1BCW A;  1AVR A;  1HVF A;  2ZOC A;  2IE7 A;  1SAV A;  2II2 A;  1AII A;  1XJL A;  2Q4C A;  2HYV A;  1BCZ A;  1HM6 A;  1YCN A;  1MCX A; 
#chains in the Genus database with same CATH topology
 4A4P A;  4JWL A;  3SOH B;  1KU1 A;  1ANX A;  2R09 A;  1R4A E;  1ANW A;  1AXN A;  1AVC A;  1HAK A;  2HYU A;  4MDU A;  3USW A;  1AVH A;  1W7B A;  1BO9 A;  3TW5 A;  2VXG A;  4EVF A;  1Q8D A;  1W45 A;  2HYW A;  1C1K A;  2H0K A;  2XO3 A;  4JMI A;  2HSN A;  1ANN A;  1N44 A;  2ZHJ A;  1XSZ A;  1BC1 A;  2ZOC A;  3ABO A;  1AII A;  2HYV A;  1BCZ A;  1MCX A;  4JXH A;  2ZHI A;  3BRX A;  1R8S E;  1HVE A;  1BC3 A;  1I4A A;  2QEZ A;  3ABR A;  1N00 A;  1BCY A;  1M9I A;  1ALA A;  1HVD A;  1BC9 A;  1R8M E;  2R0D A;  4EVH A;  4KN4 X;  1W3W A;  3ANY A;  4L5M A;  4KMU X;  1AVR A;  2II2 A;  1LKV X;  1HM6 A;  1YCN A;  1UPT B;  1BC0 A;  3USY A;  4Z21 A;  1PBV A;  3HJL A;  4C0A A;  4Q2S A;  4FQ0 C;  1A8B A;  1AEI A;  2XO2 A;  3AO0 A;  1N42 A;  1RE0 B;  1DM5 A;  2OY9 A;  2H0L A;  4C7P A;  1HVG A;  1QC7 A;  1BCW A;  1HVF A;  4D7Q A;  2IE7 A;  1S9D E;  4OIY A;  4JMO A;  4JK1 X;  1R8Q E;  1XJL A;  2Q4C A;  4MDV A;  1XT0 B;  3SWV A;  4KN7 X;  2IE6 A;  2H0M A;  4HRE A;  1A8A A;  2RAN A;  1G5N A;  1AOW A;  1N41 A;  1YJ0 A;  3LTL A;  1DK5 A;  3L8N A;  1YGM A;  3ABQ A;  2K6X A;  4FHR B;  2IIC A;  1YII A;  4X9P A;  1SAV A;  3ABS A;  3AJC A;  4D7R A; 
#chains in the Genus database with same CATH homology
 2ZHI A;  1ANX A;  3BRX A;  1BC0 A;  1ANW A;  1HVE A;  1AXN A;  1BC3 A;  1I4A A;  1AVC A;  1HAK A;  2HYU A;  1N00 A;  2IE6 A;  2H0M A;  4HRE A;  1BCY A;  1AVH A;  1M9I A;  4MDU A;  1ALA A;  1HVD A;  1W7B A;  1A8A A;  1BO9 A;  2RAN A;  1G5N A;  1AOW A;  1N41 A;  1YJ0 A;  4EVH A;  4MDV A;  4EVF A;  1W45 A;  1A8B A;  1W3W A;  1AEI A;  2XO2 A;  1DK5 A;  2HYW A;  2H0K A;  2XO3 A;  1N42 A;  1DM5 A;  1ANN A;  1N44 A;  2IIC A;  1YII A;  2H0L A;  2ZHJ A;  4X9P A;  1HVG A;  1BC1 A;  1BCW A;  1AVR A;  1HVF A;  2ZOC A;  2IE7 A;  1SAV A;  2II2 A;  1AII A;  1XJL A;  2Q4C A;  2HYV A;  1BCZ A;  1HM6 A;  1YCN A;  1MCX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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