2IE6A

Annexin v under 2.0 mpa pressure of xenon
Total Genus 135
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
318
structure length
318
Chain Sequence
ALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action
pubmed doi rcsb
molecule tags Protein and metal binding protein
molecule keywords Annexin A5
total genus 135
structure length 318
sequence length 318
ec nomenclature
pdb deposition date 2006-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A03
1W45A 1BC3A 1HVFA 1AIIA 1M9IA 1ANXA 1W7BA 1BC0A 1YCNA 2IICA 4EVHA 2ZHIA 2ZHJA 4X9PA 1BCWA 1YIIA 2HYWA 1ANNA 2HYVA 1BCZA 1DM5A 1MCXA 2IE6A 2ZOCA 1A8AA 1W3WA 1I4AA 1HM6A 1SAVA 1HVGA 2H0KA 2RANA 1HAKA 1A8BA 1AVRA 4MDVA 1BCYA 1ANWA 1HVEA 1BO9A 1AVCA 1G5NA 1DK5A 1AOWA 1N42A 1AEIA 2Q4CA 4MDUA 2HYUA 4EVFA 3BRXA 4HREA 1N00A 1XJLA 2H0MA 1YJ0A 2II2A 1N44A 2XO2A 1N41A 1AVHA 1ALAA 2H0LA 2IE7A 1AXNA 1HVDA 1BC1A 2XO3A
chains in the Genus database with same CATH superfamily
1W45A 1AIIA 1M9IA 4JMIA 4EVHA 2R09A 2ZHJA 1UPTB 4OIYA 2R0DA 2IE6A 4FHRB 1A8AA 1HM6A 1HVGA 1HAKA 1R8SE 2HSNA 1N42A 3USYA 1BC9A 1XJLA 1YJ0A 1N44A 1AVHA 1AXNA 3AO0A 1R8ME 1ANXA 1PBVA 2ZHIA 4X9PA 3USWA 1BCWA 1YIIA 1ANNA 2OY9A 1BCZA 4KN7X 3ABSA 1W3WA 1C1KA 1BCYA 1ANWA 1AVCA 1AEIA 4MDUA 4JK1X 1RE0B 3TW5A 4HREA 1N00A 2XO2A 4C0AA 1S9DE 4JWLA 2IE7A 1BC1A 1KU1A 1BC3A 1HVFA 1BC0A 2IICA 4FQ0C 3SWVA 2HYWA 1YGMA 1DM5A 1MCXA 4D7RA 2K6XA 1I4AA 1SAVA 2RANA 4A4PA 1A8BA 4MDVA 4L5MA 1G5NA 3LTLA 1DK5A 1LKVX 1Q8DA 4C7PA 2HYUA 4JXHA 4D7QA 2H0MA 2II2A 1N41A 4KMUX 1XT0B 1ALAA 2H0LA 1R4AE 2H0KA 1HVDA 2XO3A 3L8NA 3SOHB 1W7BA 1YCNA 4Z21A 1XSZA 2HYVA 2QEZA 3ANYA 2ZOCA 3HJLA 1QC7A 1AVRA 2VXGA 1HVEA 1BO9A 4JMOA 3ABOA 3ABQA 1AOWA 2Q4CA 4EVFA 3AJCA 3BRXA 3ABRA 1R8QE 4KN4X 4Q2SA
chains in the Genus database with same CATH topology
1W45A 1BC3A 1HVFA 1AIIA 1M9IA 1ANXA 1W7BA 1BC0A 1YCNA 2IICA 4EVHA 2ZHIA 2ZHJA 4X9PA 1BCWA 1YIIA 2HYWA 1ANNA 2HYVA 1BCZA 1DM5A 1MCXA 2IE6A 2ZOCA 1A8AA 1W3WA 1I4AA 1HM6A 1SAVA 1HVGA 2H0KA 2RANA 1HAKA 1A8BA 1AVRA 4MDVA 1BCYA 1ANWA 1HVEA 1BO9A 1AVCA 1G5NA 1DK5A 1AOWA 1N42A 1AEIA 2Q4CA 4MDUA 2HYUA 4EVFA 3BRXA 4HREA 1N00A 1XJLA 2H0MA 1YJ0A 2II2A 1N44A 2XO2A 1N41A 1AVHA 1ALAA 2H0LA 2IE7A 1AXNA 1HVDA 1BC1A 2XO3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W45 A;  1BC3 A;  1HVF A;  1AII A;  1M9I A;  1ANX A;  1W7B A;  1BC0 A;  1YCN A;  2IIC A;  4EVH A;  2ZHI A;  2ZHJ A;  4X9P A;  1BCW A;  1YII A;  2HYW A;  1ANN A;  2HYV A;  1BCZ A;  1DM5 A;  1MCX A;  2IE6 A;  2ZOC A;  1A8A A;  1W3W A;  1I4A A;  1HM6 A;  1SAV A;  1HVG A;  2H0K A;  2RAN A;  1HAK A;  1A8B A;  1AVR A;  4MDV A;  1BCY A;  1ANW A;  1HVE A;  1BO9 A;  1AVC A;  1G5N A;  1DK5 A;  1AOW A;  1N42 A;  1AEI A;  2Q4C A;  4MDU A;  2HYU A;  4EVF A;  3BRX A;  4HRE A;  1N00 A;  1XJL A;  2H0M A;  1YJ0 A;  2II2 A;  1N44 A;  2XO2 A;  1N41 A;  1AVH A;  1ALA A;  2H0L A;  2IE7 A;  1AXN A;  1HVD A;  1BC1 A;  2XO3 A; 
#chains in the Genus database with same CATH topology
 1W45 A;  1AII A;  1M9I A;  4JMI A;  4EVH A;  2R09 A;  2ZHJ A;  1UPT B;  4OIY A;  2R0D A;  2IE6 A;  4FHR B;  1A8A A;  1HM6 A;  1HVG A;  1HAK A;  1R8S E;  2HSN A;  1N42 A;  3USY A;  1BC9 A;  1XJL A;  1YJ0 A;  1N44 A;  1AVH A;  1AXN A;  3AO0 A;  1R8M E;  1ANX A;  1PBV A;  2ZHI A;  4X9P A;  3USW A;  1BCW A;  1YII A;  1ANN A;  2OY9 A;  1BCZ A;  4KN7 X;  3ABS A;  1W3W A;  1C1K A;  1BCY A;  1ANW A;  1AVC A;  1AEI A;  4MDU A;  4JK1 X;  1RE0 B;  3TW5 A;  4HRE A;  1N00 A;  2XO2 A;  4C0A A;  1S9D E;  4JWL A;  2IE7 A;  1BC1 A;  1KU1 A;  1BC3 A;  1HVF A;  1BC0 A;  2IIC A;  4FQ0 C;  3SWV A;  2HYW A;  1YGM A;  1DM5 A;  1MCX A;  4D7R A;  2K6X A;  1I4A A;  1SAV A;  2RAN A;  4A4P A;  1A8B A;  4MDV A;  4L5M A;  1G5N A;  3LTL A;  1DK5 A;  1LKV X;  1Q8D A;  4C7P A;  2HYU A;  4JXH A;  4D7Q A;  2H0M A;  2II2 A;  1N41 A;  4KMU X;  1XT0 B;  1ALA A;  2H0L A;  1R4A E;  2H0K A;  1HVD A;  2XO3 A;  3L8N A;  3SOH B;  1W7B A;  1YCN A;  4Z21 A;  1XSZ A;  2HYV A;  2QEZ A;  3ANY A;  2ZOC A;  3HJL A;  1QC7 A;  1AVR A;  2VXG A;  1HVE A;  1BO9 A;  4JMO A;  3ABO A;  3ABQ A;  1AOW A;  2Q4C A;  4EVF A;  3AJC A;  3BRX A;  3ABR A;  1R8Q E;  4KN4 X;  4Q2S A; 
#chains in the Genus database with same CATH homology
 1W45 A;  1BC3 A;  1HVF A;  1AII A;  1M9I A;  1ANX A;  1W7B A;  1BC0 A;  1YCN A;  2IIC A;  4EVH A;  2ZHI A;  2ZHJ A;  4X9P A;  1BCW A;  1YII A;  2HYW A;  1ANN A;  2HYV A;  1BCZ A;  1DM5 A;  1MCX A;  2IE6 A;  2ZOC A;  1A8A A;  1W3W A;  1I4A A;  1HM6 A;  1SAV A;  1HVG A;  2H0K A;  2RAN A;  1HAK A;  1A8B A;  1AVR A;  4MDV A;  1BCY A;  1ANW A;  1HVE A;  1BO9 A;  1AVC A;  1G5N A;  1DK5 A;  1AOW A;  1N42 A;  1AEI A;  2Q4C A;  4MDU A;  2HYU A;  4EVF A;  3BRX A;  4HRE A;  1N00 A;  1XJL A;  2H0M A;  1YJ0 A;  2II2 A;  1N44 A;  2XO2 A;  1N41 A;  1AVH A;  1ALA A;  2H0L A;  2IE7 A;  1AXN A;  1HVD A;  1BC1 A;  2XO3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...