2IE6A

Annexin v under 2.0 mpa pressure of xenon
Total Genus 135
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
318
structure length
318
Chain Sequence
ALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Protein and metal binding protein
publication title Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action
pubmed doi rcsb
molecule keywords Annexin A5
total genus 135
structure length 318
sequence length 318
ec nomenclature
pdb deposition date 2006-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ie6A03
2IE6A 2Q4CA 1BC0A 1ANWA 4MDUA 1AOWA 3BRXA 1W45A 2II2A 4X9PA 1YCNA 1HVFA 1HVEA 1W7BA 1AIIA 1AXNA 2ZHJA 1BC3A 1BCYA 1ALAA 1G5NA 1MCXA 2H0MA 2XO2A 4EVHA 2HYWA 1N00A 1BC1A 2ZOCA 1BO9A 1A8BA 2IE7A 1HM6A 1N44A 4MDVA 1N42A 1BCWA 1ANNA 2IICA 2ZHIA 2H0LA 1DK5A 1A8AA 2H0KA 1HVDA 1XJLA 2HYVA 1BCZA 2RANA 1ANXA 1AVRA 1M9IA 2HYUA 1SAVA 1I4AA 2XO3A 1AVCA 1YIIA 1AEIA 1HAKA 4HREA 1YJ0A 4EVFA 1AVHA 1W3WA 1N41A 1DM5A 1HVGA
chains in the Genus database with same CATH superfamily
2Q4CA 4JK1X 1W45A 1YCNA 1BC9A 4C0AA 4D7RA 1R8SE 1G5NA 4EVHA 1N00A 1BC1A 1A8BA 2IE7A 1HM6A 1R8QE 2R0DA 4JMIA 2H0LA 1DK5A 3ABSA 1XJLA 1BCZA 1ANXA 2HYUA 1XT0B 4D7QA 2XO3A 3ABQA 1AVCA 1YIIA 4KN4X 1AEIA 1HAKA 4HREA 4EVFA 1W3WA 1RE0B 1DM5A 2IE6A 3USYA 1BC0A 1ANWA 1C1KA 1QC7A 1HVFA 1HVEA 3L8NA 1AIIA 3SOHB 2HYWA 1N44A 1KU1A 2K6XA 2RANA 4Z21A 4JMOA 1M9IA 1YJ0A 3ABRA 2R09A 4X9PA 3AO0A 4KN7X 1LKVX 1AXNA 1BC3A 1ALAA 3AJCA 1MCXA 2XO2A 2ZOCA 4FHRB 1ANNA 1R4AE 4L5MA 1HVDA 1PBVA 1UPTB 2VXGA 1R8ME 1SAVA 2OY9A 3HJLA 4Q2SA 1AVHA 1N41A 3USWA 4KMUX 4MDUA 3SWVA 1AOWA 3BRXA 2II2A 3TW5A 3ANYA 1W7BA 2QEZA 4C7PA 2HSNA 2ZHJA 1BCYA 2H0MA 1BO9A 4FQ0C 3LTLA 3ABOA 4OIYA 4MDVA 1N42A 1BCWA 2IICA 4A4PA 2ZHIA 2H0KA 1YGMA 1A8AA 2HYVA 1AVRA 1XSZA 1I4AA 4JWLA 1Q8DA 1S9DE 4JXHA 1HVGA
chains in the Genus database with same CATH topology
2IE6A 2Q4CA 1BC0A 1ANWA 4MDUA 1AOWA 3BRXA 1W45A 2II2A 4X9PA 1YCNA 1HVFA 1HVEA 1W7BA 1AIIA 1AXNA 2ZHJA 1BC3A 1BCYA 1ALAA 1G5NA 1MCXA 2H0MA 2XO2A 4EVHA 2HYWA 1N00A 1BC1A 2ZOCA 1BO9A 1A8BA 2IE7A 1HM6A 1N44A 4MDVA 1N42A 1BCWA 1ANNA 2IICA 2ZHIA 2H0LA 1DK5A 1A8AA 2H0KA 1HVDA 1XJLA 2HYVA 1BCZA 2RANA 1ANXA 1AVRA 1M9IA 2HYUA 1SAVA 1I4AA 2XO3A 1AVCA 1YIIA 1AEIA 1HAKA 4HREA 1YJ0A 4EVFA 1AVHA 1W3WA 1N41A 1DM5A 1HVGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IE6 A;  2Q4C A;  1BC0 A;  1ANW A;  4MDU A;  1AOW A;  3BRX A;  1W45 A;  2II2 A;  4X9P A;  1YCN A;  1HVF A;  1HVE A;  1W7B A;  1AII A;  1AXN A;  2ZHJ A;  1BC3 A;  1BCY A;  1ALA A;  1G5N A;  1MCX A;  2H0M A;  2XO2 A;  4EVH A;  2HYW A;  1N00 A;  1BC1 A;  2ZOC A;  1BO9 A;  1A8B A;  2IE7 A;  1HM6 A;  1N44 A;  4MDV A;  1N42 A;  1BCW A;  1ANN A;  2IIC A;  2ZHI A;  2H0L A;  1DK5 A;  1A8A A;  2H0K A;  1HVD A;  1XJL A;  2HYV A;  1BCZ A;  2RAN A;  1ANX A;  1AVR A;  1M9I A;  2HYU A;  1SAV A;  1I4A A;  2XO3 A;  1AVC A;  1YII A;  1AEI A;  1HAK A;  4HRE A;  1YJ0 A;  4EVF A;  1AVH A;  1W3W A;  1N41 A;  1DM5 A;  1HVG A; 
#chains in the Genus database with same CATH topology
 2Q4C A;  4JK1 X;  1W45 A;  1YCN A;  1BC9 A;  4C0A A;  4D7R A;  1R8S E;  1G5N A;  4EVH A;  1N00 A;  1BC1 A;  1A8B A;  2IE7 A;  1HM6 A;  1R8Q E;  2R0D A;  4JMI A;  2H0L A;  1DK5 A;  3ABS A;  1XJL A;  1BCZ A;  1ANX A;  2HYU A;  1XT0 B;  4D7Q A;  2XO3 A;  3ABQ A;  1AVC A;  1YII A;  4KN4 X;  1AEI A;  1HAK A;  4HRE A;  4EVF A;  1W3W A;  1RE0 B;  1DM5 A;  2IE6 A;  3USY A;  1BC0 A;  1ANW A;  1C1K A;  1QC7 A;  1HVF A;  1HVE A;  3L8N A;  1AII A;  3SOH B;  2HYW A;  1N44 A;  1KU1 A;  2K6X A;  2RAN A;  4Z21 A;  4JMO A;  1M9I A;  1YJ0 A;  3ABR A;  2R09 A;  4X9P A;  3AO0 A;  4KN7 X;  1LKV X;  1AXN A;  1BC3 A;  1ALA A;  3AJC A;  1MCX A;  2XO2 A;  2ZOC A;  4FHR B;  1ANN A;  1R4A E;  4L5M A;  1HVD A;  1PBV A;  1UPT B;  2VXG A;  1R8M E;  1SAV A;  2OY9 A;  3HJL A;  4Q2S A;  1AVH A;  1N41 A;  3USW A;  4KMU X;  4MDU A;  3SWV A;  1AOW A;  3BRX A;  2II2 A;  3TW5 A;  3ANY A;  1W7B A;  2QEZ A;  4C7P A;  2HSN A;  2ZHJ A;  1BCY A;  2H0M A;  1BO9 A;  4FQ0 C;  3LTL A;  3ABO A;  4OIY A;  4MDV A;  1N42 A;  1BCW A;  2IIC A;  4A4P A;  2ZHI A;  2H0K A;  1YGM A;  1A8A A;  2HYV A;  1AVR A;  1XSZ A;  1I4A A;  4JWL A;  1Q8D A;  1S9D E;  4JXH A;  1HVG A; 
#chains in the Genus database with same CATH homology
 2IE6 A;  2Q4C A;  1BC0 A;  1ANW A;  4MDU A;  1AOW A;  3BRX A;  1W45 A;  2II2 A;  4X9P A;  1YCN A;  1HVF A;  1HVE A;  1W7B A;  1AII A;  1AXN A;  2ZHJ A;  1BC3 A;  1BCY A;  1ALA A;  1G5N A;  1MCX A;  2H0M A;  2XO2 A;  4EVH A;  2HYW A;  1N00 A;  1BC1 A;  2ZOC A;  1BO9 A;  1A8B A;  2IE7 A;  1HM6 A;  1N44 A;  4MDV A;  1N42 A;  1BCW A;  1ANN A;  2IIC A;  2ZHI A;  2H0L A;  1DK5 A;  1A8A A;  2H0K A;  1HVD A;  1XJL A;  2HYV A;  1BCZ A;  2RAN A;  1ANX A;  1AVR A;  1M9I A;  2HYU A;  1SAV A;  1I4A A;  2XO3 A;  1AVC A;  1YII A;  1AEI A;  1HAK A;  4HRE A;  1YJ0 A;  4EVF A;  1AVH A;  1W3W A;  1N41 A;  1DM5 A;  1HVG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...