2IE7 | Genus

Total Genus 136

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	136
sequence length	318
structure length	318
Chain Sequence	ALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein and metal binding protein
publication title	Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action pubmed doi rcsb
molecule keywords	Annexin A5
total genus	136
structure length	318
sequence length	318
ec nomenclature
pdb deposition date	2006-09-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00191	Annexin	Annexin

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ie7A02
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ie7A04
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ie7A01
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ie7A03

1YCNA 1HVFA 2H0KA 1N41A 2Q4CA 2IE7A 1A8BA 1ANWA 1N44A 1SAVA 1HM6A 1ALAA 1BCZA 1YIIA 1HAKA 2II2A 2IE6A 1HVEA 3BRXA 1AOWA 2HYWA 2XO3A 1BO9A 1AVCA 1N42A 2HYUA 2ZOCA 4HREA 1M9IA 2RANA 1W7BA 2HYVA 1W45A 1AVHA 1A8AA 1BC1A 2ZHJA 1G5NA 1I4AA 1DM5A 1HVGA 1MCXA 4X9PA 1ANXA 2XO2A 1BCYA 1BC3A 1ANNA 2IICA 1YJ0A 1XJLA 2H0MA 1HVDA 1AXNA 1BC0A 1AVRA 1AEIA 1N00A 4MDUA 2ZHIA 4EVHA 1AIIA 2H0LA 4MDVA 1DK5A 1BCWA 4EVFA 1W3WA
chains in the Genus database with same CATH superfamily

1HVFA 2H0KA 1N41A 1HM6A 1YIIA 2VXGA 1HVEA 1BO9A 1AVCA 2ZOCA 4HREA 1W45A 1A8AA 3L8NA 4Q2SA 4X9PA 1ANXA 1R8SE 1BCYA 1BC9A 3HJLA 1QC7A 1AXNA 4EVHA 1AVRA 3AJCA 3LTLA 1BC1A 4EVFA 1W3WA 1C1KA 3USYA 2Q4CA 2IE7A 1ANWA 1N44A 1ALAA 3TW5A 3BRXA 3AO0A 2XO3A 4JWLA 4L5MA 1UPTB 1M9IA 1LKVX 2HYVA 4D7QA 1HVGA 1MCXA 1R4AE 2XO2A 1R8QE 4JK1X 2R0DA 1YJ0A 3ABOA 4KN4X 1BC0A 4FQ0C 1AEIA 1N00A 1S9DE 3SWVA 4D7RA 4C7PA 1A8BA 1SAVA 1BCZA 2II2A 1PBVA 1YGMA 4Z21A 4C0AA 1RE0B 2OY9A 1W7BA 1Q8DA 2ZHJA 3USWA 1I4AA 1KU1A 3ABRA 1ANNA 1XJLA 1HVDA 4MDUA 3ANYA 2HSNA 2H0LA 1DK5A 4KN7X 4OIYA 1BCWA 1YCNA 2K6XA 1HAKA 2IE6A 1AOWA 2HYWA 3ABQA 2R09A 1N42A 4JXHA 2QEZA 4A4PA 2RANA 4JMOA 1AVHA 1G5NA 1DM5A 1XSZA 1BC3A 1XT0B 2IICA 2H0MA 4FHRB 4JMIA 4KMUX 2ZHIA 1AIIA 1R8ME 4MDVA 3ABSA 2HYUA 3SOHB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1YCN A;  1HVF A;  2H0K A;  1N41 A;  2Q4C A;  2IE7 A;  1A8B A;  1ANW A;  1N44 A;  1SAV A;  1HM6 A;  1ALA A;  1BCZ A;  1YII A;  1HAK A;  2II2 A;  2IE6 A;  1HVE A;  3BRX A;  1AOW A;  2HYW A;  2XO3 A;  1BO9 A;  1AVC A;  1N42 A;  2HYU A;  2ZOC A;  4HRE A;  1M9I A;  2RAN A;  1W7B A;  2HYV A;  1W45 A;  1AVH A;  1A8A A;  1BC1 A;  2ZHJ A;  1G5N A;  1I4A A;  1DM5 A;  1HVG A;  1MCX A;  4X9P A;  1ANX A;  2XO2 A;  1BCY A;  1BC3 A;  1ANN A;  2IIC A;  1YJ0 A;  1XJL A;  2H0M A;  1HVD A;  1AXN A;  1BC0 A;  1AVR A;  1AEI A;  1N00 A;  4MDU A;  2ZHI A;  4EVH A;  1AII A;  2H0L A;  4MDV A;  1DK5 A;  1BCW A;  4EVF A;  1W3W A; 
#chains in the Genus database with same CATH topology
 1HVF A;  2H0K A;  1N41 A;  1HM6 A;  1YII A;  2VXG A;  1HVE A;  1BO9 A;  1AVC A;  2ZOC A;  4HRE A;  1W45 A;  1A8A A;  3L8N A;  4Q2S A;  4X9P A;  1ANX A;  1R8S E;  1BCY A;  1BC9 A;  3HJL A;  1QC7 A;  1AXN A;  4EVH A;  1AVR A;  3AJC A;  3LTL A;  1BC1 A;  4EVF A;  1W3W A;  1C1K A;  3USY A;  2Q4C A;  2IE7 A;  1ANW A;  1N44 A;  1ALA A;  3TW5 A;  3BRX A;  3AO0 A;  2XO3 A;  4JWL A;  4L5M A;  1UPT B;  1M9I A;  1LKV X;  2HYV A;  4D7Q A;  1HVG A;  1MCX A;  1R4A E;  2XO2 A;  1R8Q E;  4JK1 X;  2R0D A;  1YJ0 A;  3ABO A;  4KN4 X;  1BC0 A;  4FQ0 C;  1AEI A;  1N00 A;  1S9D E;  3SWV A;  4D7R A;  4C7P A;  1A8B A;  1SAV A;  1BCZ A;  2II2 A;  1PBV A;  1YGM A;  4Z21 A;  4C0A A;  1RE0 B;  2OY9 A;  1W7B A;  1Q8D A;  2ZHJ A;  3USW A;  1I4A A;  1KU1 A;  3ABR A;  1ANN A;  1XJL A;  1HVD A;  4MDU A;  3ANY A;  2HSN A;  2H0L A;  1DK5 A;  4KN7 X;  4OIY A;  1BCW A;  1YCN A;  2K6X A;  1HAK A;  2IE6 A;  1AOW A;  2HYW A;  3ABQ A;  2R09 A;  1N42 A;  4JXH A;  2QEZ A;  4A4P A;  2RAN A;  4JMO A;  1AVH A;  1G5N A;  1DM5 A;  1XSZ A;  1BC3 A;  1XT0 B;  2IIC A;  2H0M A;  4FHR B;  4JMI A;  4KMU X;  2ZHI A;  1AII A;  1R8M E;  4MDV A;  3ABS A;  2HYU A;  3SOH B; 
#chains in the Genus database with same CATH homology
 1YCN A;  1HVF A;  2H0K A;  1N41 A;  2Q4C A;  2IE7 A;  1A8B A;  1ANW A;  1N44 A;  1SAV A;  1HM6 A;  1ALA A;  1BCZ A;  1YII A;  1HAK A;  2II2 A;  2IE6 A;  1HVE A;  3BRX A;  1AOW A;  2HYW A;  2XO3 A;  1BO9 A;  1AVC A;  1N42 A;  2HYU A;  2ZOC A;  4HRE A;  1M9I A;  2RAN A;  1W7B A;  2HYV A;  1W45 A;  1AVH A;  1A8A A;  1BC1 A;  2ZHJ A;  1G5N A;  1I4A A;  1DM5 A;  1HVG A;  1MCX A;  4X9P A;  1ANX A;  2XO2 A;  1BCY A;  1BC3 A;  1ANN A;  2IIC A;  1YJ0 A;  1XJL A;  2H0M A;  1HVD A;  1AXN A;  1BC0 A;  1AVR A;  1AEI A;  1N00 A;  4MDU A;  2ZHI A;  4EVH A;  1AII A;  2H0L A;  4MDV A;  1DK5 A;  1BCW A;  4EVF A;  1W3W A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2IE7A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations