2II2 | Genus

Total Genus 128

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	128
sequence length	304
structure length	304
Chain Sequence	YGDAIPEVKAILEAKNEEELVTFTSRWSAEERKELRTQFQDTTGLEFIAFLKKCIKNGPYEDVMALGWDCNISARVNVIKKAMKNVNDFRAIHDVVLIATPDERLKLAQAYKEKTGNDLLQDFVDQIPLTSAASYLCHLAIRENRTPRGSVASDAEVLKHNLIDADEPDHEAVVRLIITSTADEYKEINHRFEVLTGKSVQEAIETRYADKENARGLCIAHYYNLAPARAVAYAFHSAVETQNDDMAYEQAARITGLFHDLHKFAWVHYACWGVMRDDILSRFQSKEANKVNFRDACLMFWKLA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 304 atoms

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304 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Metal binding protein
source organism	Giardia intestinalis
publication title	Apo and Calcium-bound Crystal Structures of Alpha-11 Giardin, an Unusual Annexin from Giardia lamblia pubmed doi rcsb
molecule keywords	Alpha-11 giardin
total genus	128
structure length	304
sequence length	304
ec nomenclature
pdb deposition date	2006-09-27

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ii2A04
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ii2A01
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ii2A02
1.10.220.10	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin	2ii2A03

1AVCA 1SAVA 4HREA 1AVRA 1AOWA 1A8BA 1DM5A 1W3WA 4MDVA 2ZHJA 3BRXA 1BC3A 1I4AA 2H0MA 2IICA 2ZOCA 1AXNA 1HVDA 1N00A 2ZHIA 1BO9A 4EVHA 1HVGA 1AEIA 1A8AA 1HVEA 1AVHA 1G5NA 4EVFA 2RANA 2IE6A 2XO2A 4X9PA 1BCZA 1HVFA 1YCNA 2H0KA 2HYUA 1HM6A 2Q4CA 2HYWA 1W7BA 1BCYA 1HAKA 1MCXA 1BC1A 2HYVA 1ANWA 1ANNA 1XJLA 2IE7A 1N41A 1BC0A 1AIIA 1BCWA 2XO3A 1ANXA 2II2A 1N42A 1ALAA 1DK5A 1YIIA 1W45A 1YJ0A 1M9IA 2H0LA 1N44A 4MDUA
chains in the Genus database with same CATH superfamily

4Q2SA 1AVRA 1AOWA 1DM5A 4C0AA 3ABQA 2ZOCA 4C7PA 1AEIA 1A8AA 2R09A 1PBVA 4EVFA 1R8QE 2HYUA 1BCYA 1MCXA 1BC1A 1ANWA 1ANNA 1XJLA 3TW5A 1Q8DA 1QC7A 1R8ME 1BCWA 3USWA 1ALAA 1DK5A 4JK1X 1XT0B 2OY9A 1S9DE 1XSZA 4MDUA 4FQ0C 1R4AE 1W3WA 2ZHJA 1I4AA 1AXNA 1C1KA 1N00A 1HVGA 2QEZA 3ABOA 2RANA 4X9PA 1KU1A 1BCZA 1HM6A 3ANYA 4L5MA 1BC9A 2HYWA 2R0DA 2HYVA 3SOHB 1BC0A 2XO3A 4D7RA 2K6XA 1ANXA 1N42A 3USYA 4KMUX 1YJ0A 1YGMA 2H0LA 1UPTB 4FHRB 4HREA 4D7QA 3HJLA 3BRXA 1BC3A 3SWVA 2ZHIA 2VXGA 4EVHA 4JMIA 2IE6A 2XO2A 4KN4X 2H0KA 3ABSA 2Q4CA 1W7BA 2HSNA 4KN7X 4OIYA 1AIIA 4JXHA 2II2A 1R8SE 3L8NA 1M9IA 1N44A 1AVCA 1SAVA 1A8BA 4MDVA 2H0MA 2IICA 1HVDA 4A4PA 1BO9A 4Z21A 1HVEA 1AVHA 1LKVX 4JMOA 1G5NA 3ABRA 1HVFA 1YCNA 3LTLA 1HAKA 2IE7A 3AO0A 4JWLA 1N41A 3AJCA 1RE0B 1YIIA 1W45A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1AVC A;  1SAV A;  4HRE A;  1AVR A;  1AOW A;  1A8B A;  1DM5 A;  1W3W A;  4MDV A;  2ZHJ A;  3BRX A;  1BC3 A;  1I4A A;  2H0M A;  2IIC A;  2ZOC A;  1AXN A;  1HVD A;  1N00 A;  2ZHI A;  1BO9 A;  4EVH A;  1HVG A;  1AEI A;  1A8A A;  1HVE A;  1AVH A;  1G5N A;  4EVF A;  2RAN A;  2IE6 A;  2XO2 A;  4X9P A;  1BCZ A;  1HVF A;  1YCN A;  2H0K A;  2HYU A;  1HM6 A;  2Q4C A;  2HYW A;  1W7B A;  1BCY A;  1HAK A;  1MCX A;  1BC1 A;  2HYV A;  1ANW A;  1ANN A;  1XJL A;  2IE7 A;  1N41 A;  1BC0 A;  1AII A;  1BCW A;  2XO3 A;  1ANX A;  2II2 A;  1N42 A;  1ALA A;  1DK5 A;  1YII A;  1W45 A;  1YJ0 A;  1M9I A;  2H0L A;  1N44 A;  4MDU A; 
#chains in the Genus database with same CATH topology
 4Q2S A;  1AVR A;  1AOW A;  1DM5 A;  4C0A A;  3ABQ A;  2ZOC A;  4C7P A;  1AEI A;  1A8A A;  2R09 A;  1PBV A;  4EVF A;  1R8Q E;  2HYU A;  1BCY A;  1MCX A;  1BC1 A;  1ANW A;  1ANN A;  1XJL A;  3TW5 A;  1Q8D A;  1QC7 A;  1R8M E;  1BCW A;  3USW A;  1ALA A;  1DK5 A;  4JK1 X;  1XT0 B;  2OY9 A;  1S9D E;  1XSZ A;  4MDU A;  4FQ0 C;  1R4A E;  1W3W A;  2ZHJ A;  1I4A A;  1AXN A;  1C1K A;  1N00 A;  1HVG A;  2QEZ A;  3ABO A;  2RAN A;  4X9P A;  1KU1 A;  1BCZ A;  1HM6 A;  3ANY A;  4L5M A;  1BC9 A;  2HYW A;  2R0D A;  2HYV A;  3SOH B;  1BC0 A;  2XO3 A;  4D7R A;  2K6X A;  1ANX A;  1N42 A;  3USY A;  4KMU X;  1YJ0 A;  1YGM A;  2H0L A;  1UPT B;  4FHR B;  4HRE A;  4D7Q A;  3HJL A;  3BRX A;  1BC3 A;  3SWV A;  2ZHI A;  2VXG A;  4EVH A;  4JMI A;  2IE6 A;  2XO2 A;  4KN4 X;  2H0K A;  3ABS A;  2Q4C A;  1W7B A;  2HSN A;  4KN7 X;  4OIY A;  1AII A;  4JXH A;  2II2 A;  1R8S E;  3L8N A;  1M9I A;  1N44 A;  1AVC A;  1SAV A;  1A8B A;  4MDV A;  2H0M A;  2IIC A;  1HVD A;  4A4P A;  1BO9 A;  4Z21 A;  1HVE A;  1AVH A;  1LKV X;  4JMO A;  1G5N A;  3ABR A;  1HVF A;  1YCN A;  3LTL A;  1HAK A;  2IE7 A;  3AO0 A;  4JWL A;  1N41 A;  3AJC A;  1RE0 B;  1YII A;  1W45 A; 
#chains in the Genus database with same CATH homology
 1AVC A;  1SAV A;  4HRE A;  1AVR A;  1AOW A;  1A8B A;  1DM5 A;  1W3W A;  4MDV A;  2ZHJ A;  3BRX A;  1BC3 A;  1I4A A;  2H0M A;  2IIC A;  2ZOC A;  1AXN A;  1HVD A;  1N00 A;  2ZHI A;  1BO9 A;  4EVH A;  1HVG A;  1AEI A;  1A8A A;  1HVE A;  1AVH A;  1G5N A;  4EVF A;  2RAN A;  2IE6 A;  2XO2 A;  4X9P A;  1BCZ A;  1HVF A;  1YCN A;  2H0K A;  2HYU A;  1HM6 A;  2Q4C A;  2HYW A;  1W7B A;  1BCY A;  1HAK A;  1MCX A;  1BC1 A;  2HYV A;  1ANW A;  1ANN A;  1XJL A;  2IE7 A;  1N41 A;  1BC0 A;  1AII A;  1BCW A;  2XO3 A;  1ANX A;  2II2 A;  1N42 A;  1ALA A;  1DK5 A;  1YII A;  1W45 A;  1YJ0 A;  1M9I A;  2H0L A;  1N44 A;  4MDU A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2II2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN