2J1QA

Crystal structure of trypanosoma cruzi arginine kinase
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
355
structure length
339
Chain Sequence
MASAEVVSKLEAAFAKLQNASDCHSLLKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVENLDSGIGVYAPDAESYTLFAALLDPIIEDYHKGFKPSDKQPPKDSGDLNTFIDVDPDKKYVISTRVRCGRSLEGYPFNPCLKKQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLIDDHFLFKEGDRFLQAAHACKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKEVFGRLVTAVGVIEEKVKFSRDDRLGFLTFCPTNLGTTIRASVHIKLPRKKLEEVAAKYNLQVRGVYDISNKRRLGLSEYEAVKEMQDGILELIKAEES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Trypanosoma Cruzi Arginine Kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma cruzi
molecule keywords ARGININE KINASE
total genus 116
structure length 339
sequence length 355
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2006-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 2j1qA01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 2j1qA02
1HTQA 1P50A 1RL9A 2LGSA 4HPPA 2WGSA 4S17A 4GW2A 2WHIA 3JPZA 3JU5A 5J9AA 4RF7A 4GVYA 3ZXVA 1FPYA 4BHLA 2GLSA 1BG0A 3L2EA 4BG4B 4GVZA 4RF9A 4LNOA 3B6RA 4RF8A 2BVCA 2CRKA 1G0WA 1P52A 1U6RA 4LNIA 4AM1A 4LNNA 4S0RA 3DREA 1SD0A 1VRPA 3M10A 3JQ3A 1M15A 1LGRA 4RF6A 5J99A 1HTOA 4ACFA 2J1QA 4GW0A 4XYCA 3NG0A 1F1HA 3L2EB 1QH4A 4Z9MA 4LNKA 3ZXRA 4BG4A 1F52A 1I0EA 4Q2RA 4LNFA 1QK1A 3L2DA 3DRBA 3JU6A 1CRKA
chains in the Genus database with same CATH superfamily
1P50A 2WGSA 3JPZA 4GVYA 2D33A 2D3CA 1BG0A 3L2EA 4RF9A 4S0RA 4LNIA 3LN6A 4AM1A 1VRPA 3M10A 1TT4A 1M15A 1LGRA 3ZXRA 3L2EB 3NZTA 4Q2RA 4LNFA 1CRKA 2D3BA 3FKYA 4HPPA 3ZXVA 1G0WA 1P52A 4RF6A 4ACFA 3NG0A 2GWDA 4Z9MA 1V4GA 4BG4A 1R8GA 1QK1A 4RF7A 4GVZA 2GWCA 1HTQA 2D32A 1RL9A 2LGSA 3IG5A 1VA6A 2WHIA 3JU5A 3LN7A 5J9AA 4BHLA 4LNOA 4BG4B 2CRKA 1U6RA 2OJWA 3IG8A 5J99A 1HTOA 4GW0A 4LNKA 1F52A 1I0EA 3DRBA 2UU7A 4S17A 4GW2A 1FPYA 2D3AA 2GLSA 4BAXA 3B6RA 4RF8A 2QC8A 2BVCA 4LNNA 3LVVA 3DREA 1SD0A 3JQ3A 2J1QA 3LVWA 4XYCA 1F1HA 1QH4A 3L2DA 3JU6A
chains in the Genus database with same CATH topology
1HTQA 1P50A 1RL9A 2LGSA 4HPPA 2WGSA 4S17A 4GW2A 2WHIA 3JPZA 3JU5A 5J9AA 4RF7A 4GVYA 3ZXVA 1FPYA 4BHLA 2GLSA 1BG0A 3L2EA 4BG4B 4GVZA 4RF9A 4LNOA 3B6RA 4RF8A 2BVCA 2CRKA 1G0WA 1P52A 1U6RA 4LNIA 4AM1A 4LNNA 4S0RA 3DREA 1SD0A 1VRPA 3M10A 3JQ3A 1M15A 1LGRA 4RF6A 5J99A 1HTOA 4ACFA 2J1QA 4GW0A 4XYCA 3NG0A 1F1HA 3L2EB 1QH4A 4Z9MA 4LNKA 3ZXRA 4BG4A 1F52A 1I0EA 4Q2RA 4LNFA 1QK1A 3L2DA 3DRBA 3JU6A 1CRKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HTQ A;  1P50 A;  1RL9 A;  2LGS A;  4HPP A;  2WGS A;  4S17 A;  4GW2 A;  2WHI A;  3JPZ A;  3JU5 A;  5J9A A;  4RF7 A;  4GVY A;  3ZXV A;  1FPY A;  4BHL A;  2GLS A;  1BG0 A;  3L2E A;  4BG4 B;  4GVZ A;  4RF9 A;  4LNO A;  3B6R A;  4RF8 A;  2BVC A;  2CRK A;  1G0W A;  1P52 A;  1U6R A;  4LNI A;  4AM1 A;  4LNN A;  4S0R A;  3DRE A;  1SD0 A;  1VRP A;  3M10 A;  3JQ3 A;  1M15 A;  1LGR A;  4RF6 A;  5J99 A;  1HTO A;  4ACF A;  2J1Q A;  4GW0 A;  4XYC A;  3NG0 A;  1F1H A;  3L2E B;  1QH4 A;  4Z9M A;  4LNK A;  3ZXR A;  4BG4 A;  1F52 A;  1I0E A;  4Q2R A;  4LNF A;  1QK1 A;  3L2D A;  3DRB A;  3JU6 A;  1CRK A; 
#chains in the Genus database with same CATH topology
 1P50 A;  2WGS A;  3JPZ A;  4GVY A;  2D33 A;  2D3C A;  1BG0 A;  3L2E A;  4RF9 A;  4S0R A;  4LNI A;  3LN6 A;  4AM1 A;  1VRP A;  3M10 A;  1TT4 A;  1M15 A;  1LGR A;  3ZXR A;  3L2E B;  3NZT A;  4Q2R A;  4LNF A;  1CRK A;  2D3B A;  3FKY A;  4HPP A;  3ZXV A;  1G0W A;  1P52 A;  4RF6 A;  4ACF A;  3NG0 A;  2GWD A;  4Z9M A;  1V4G A;  4BG4 A;  1R8G A;  1QK1 A;  4RF7 A;  4GVZ A;  2GWC A;  1HTQ A;  2D32 A;  1RL9 A;  2LGS A;  3IG5 A;  1VA6 A;  2WHI A;  3JU5 A;  3LN7 A;  5J9A A;  4BHL A;  4LNO A;  4BG4 B;  2CRK A;  1U6R A;  2OJW A;  3IG8 A;  5J99 A;  1HTO A;  4GW0 A;  4LNK A;  1F52 A;  1I0E A;  3DRB A;  2UU7 A;  4S17 A;  4GW2 A;  1FPY A;  2D3A A;  2GLS A;  4BAX A;  3B6R A;  4RF8 A;  2QC8 A;  2BVC A;  4LNN A;  3LVV A;  3DRE A;  1SD0 A;  3JQ3 A;  2J1Q A;  3LVW A;  4XYC A;  1F1H A;  1QH4 A;  3L2D A;  3JU6 A; 
#chains in the Genus database with same CATH homology
 1HTQ A;  1P50 A;  1RL9 A;  2LGS A;  4HPP A;  2WGS A;  4S17 A;  4GW2 A;  2WHI A;  3JPZ A;  3JU5 A;  5J9A A;  4RF7 A;  4GVY A;  3ZXV A;  1FPY A;  4BHL A;  2GLS A;  1BG0 A;  3L2E A;  4BG4 B;  4GVZ A;  4RF9 A;  4LNO A;  3B6R A;  4RF8 A;  2BVC A;  2CRK A;  1G0W A;  1P52 A;  1U6R A;  4LNI A;  4AM1 A;  4LNN A;  4S0R A;  3DRE A;  1SD0 A;  1VRP A;  3M10 A;  3JQ3 A;  1M15 A;  1LGR A;  4RF6 A;  5J99 A;  1HTO A;  4ACF A;  2J1Q A;  4GW0 A;  4XYC A;  3NG0 A;  1F1H A;  3L2E B;  1QH4 A;  4Z9M A;  4LNK A;  3ZXR A;  4BG4 A;  1F52 A;  1I0E A;  4Q2R A;  4LNF A;  1QK1 A;  3L2D A;  3DRB A;  3JU6 A;  1CRK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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