3DRB | Genus

Total Genus 128

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	128
sequence length	376
structure length	376
Chain Sequence	SHNALKLRFPAEDEFPDLSAHNNHMAKVLTPELYAELRAKSTPSGFTLDDVIQTGVDNPGHPYIMTVGCVAGDEESYEVFKDLFDPIIEDRHGGYKPSDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structural studies of human brain-type creatine kinase complexed with the ADP-Mg2+-NO3- -creatine transition-state analogue complex pubmed doi rcsb
molecule keywords	Creatine kinase B-type
molecule tags	Transferase
source organism	Homo sapiens
total genus	128
structure length	376
sequence length	376
chains with identical sequence	B
ec nomenclature	ec 2.7.3.2: Creatine kinase.
pdb deposition date	2008-07-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00217	ATP-gua_Ptrans	ATP:guanido phosphotransferase, C-terminal catalytic domain
A	PF02807	ATP-gua_PtransN	ATP:guanido phosphotransferase, N-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.135.10	Mainly Alpha	Orthogonal Bundle	Transferase Creatine Kinase; Chain A, domain 1	ATP:guanido phosphotransferase, N-terminal domain	3drbA01
3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase; Chain A, domain 2	Glutamine synthetase/guanido kinase, catalytic domain	3drbA02

3ZXVA 1G0WA 1QH4A 1LGRA 4GW2A 3B6RA 4Q2RA 5J9AA 4HPPA 1SD0A 5J99A 4BG4A 4LNIA 2CRKA 4RF8A 2WHIA 4S17A 2GLSA 4LNKA 4ACFA 1I0EA 1F52A 4GW0A 3JU5A 1QK1A 3JPZA 1HTQA 3NG0A 4RF6A 4Z9MA 4RF9A 1FPYA 1F1HA 3JU6A 4AM1A 4LNNA 2J1QA 1VRPA 3DREA 3JQ3A 1P52A 4GVYA 4BHLA 1BG0A 3DRBA 3L2EB 4GVZA 1U6RA 1P50A 1HTOA 4LNFA 4S0RA 4XYCA 2BVCA 3M10A 2WGSA 4LNOA 2LGSA 4BG4B 1RL9A 3L2DA 4RF7A 3ZXRA 3L2EA 1CRKA 1M15A
chains in the Genus database with same CATH superfamily

3ZXVA 1G0WA 1QH4A 1LGRA 4GW2A 1SD0A 2UU7A 3LN7A 2GWDA 1FPYA 2D32A 1F1HA 3IG5A 1P52A 4BHLA 2D3CA 3DRBA 1U6RA 4S0RA 3FKYA 2LGSA 4BAXA 1V4GA 3NZTA 1CRKA 1M15A 5J9AA 4HPPA 4LNIA 4S17A 2GLSA 1TT4A 4ACFA 1F52A 4RF6A 4Z9MA 4GVYA 1BG0A 3M10A 1RL9A 4RF7A 3L2EA 2QC8A 2D33A 3B6RA 2CRKA 3JU5A 1QK1A 3JPZA 1HTQA 2GWCA 2D3AA 2J1QA 3DREA 3JQ3A 4LNFA 3L2EB 4GVZA 1P50A 4BG4B 3ZXRA 4Q2RA 5J99A 4BG4A 1R8GA 4RF8A 2WHIA 3LN6A 1I0EA 3LVWA 4GW0A 2OJWA 3NG0A 4RF9A 1VA6A 4XYCA 3JU6A 4AM1A 4LNNA 2D3BA 4LNKA 1VRPA 3LVVA 1HTOA 2BVCA 2WGSA 4LNOA 3L2DA 3IG8A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3ZXV A;  1G0W A;  1QH4 A;  1LGR A;  4GW2 A;  3B6R A;  4Q2R A;  5J9A A;  4HPP A;  1SD0 A;  5J99 A;  4BG4 A;  4LNI A;  2CRK A;  4RF8 A;  2WHI A;  4S17 A;  2GLS A;  4LNK A;  4ACF A;  1I0E A;  1F52 A;  4GW0 A;  3JU5 A;  1QK1 A;  3JPZ A;  1HTQ A;  3NG0 A;  4RF6 A;  4Z9M A;  4RF9 A;  1FPY A;  1F1H A;  3JU6 A;  4AM1 A;  4LNN A;  2J1Q A;  1VRP A;  3DRE A;  3JQ3 A;  1P52 A;  4GVY A;  4BHL A;  1BG0 A;  3DRB A;  3L2E B;  4GVZ A;  1U6R A;  1P50 A;  1HTO A;  4LNF A;  4S0R A;  4XYC A;  2BVC A;  3M10 A;  2WGS A;  4LNO A;  2LGS A;  4BG4 B;  1RL9 A;  3L2D A;  4RF7 A;  3ZXR A;  3L2E A;  1CRK A;  1M15 A; 
#chains in the Genus database with same CATH topology
 3ZXV A;  1G0W A;  1QH4 A;  1LGR A;  4GW2 A;  1SD0 A;  2UU7 A;  3LN7 A;  2GWD A;  1FPY A;  2D32 A;  1F1H A;  3IG5 A;  1P52 A;  4BHL A;  2D3C A;  3DRB A;  1U6R A;  4S0R A;  3FKY A;  2LGS A;  4BAX A;  1V4G A;  3NZT A;  1CRK A;  1M15 A;  5J9A A;  4HPP A;  4LNI A;  4S17 A;  2GLS A;  1TT4 A;  4ACF A;  1F52 A;  4RF6 A;  4Z9M A;  4GVY A;  1BG0 A;  3M10 A;  1RL9 A;  4RF7 A;  3L2E A;  2QC8 A;  2D33 A;  3B6R A;  2CRK A;  3JU5 A;  1QK1 A;  3JPZ A;  1HTQ A;  2GWC A;  2D3A A;  2J1Q A;  3DRE A;  3JQ3 A;  4LNF A;  3L2E B;  4GVZ A;  1P50 A;  4BG4 B;  3ZXR A;  4Q2R A;  5J99 A;  4BG4 A;  1R8G A;  4RF8 A;  2WHI A;  3LN6 A;  1I0E A;  3LVW A;  4GW0 A;  2OJW A;  3NG0 A;  4RF9 A;  1VA6 A;  4XYC A;  3JU6 A;  4AM1 A;  4LNN A;  2D3B A;  4LNK A;  1VRP A;  3LVV A;  1HTO A;  2BVC A;  2WGS A;  4LNO A;  3L2D A;  3IG8 A; 
#chains in the Genus database with same CATH homology
 3ZXV A;  1G0W A;  1QH4 A;  1LGR A;  4GW2 A;  3B6R A;  4Q2R A;  5J9A A;  4HPP A;  1SD0 A;  5J99 A;  4BG4 A;  4LNI A;  2CRK A;  4RF8 A;  2WHI A;  4S17 A;  2GLS A;  4LNK A;  4ACF A;  1I0E A;  1F52 A;  4GW0 A;  3JU5 A;  1QK1 A;  3JPZ A;  1HTQ A;  3NG0 A;  4RF6 A;  4Z9M A;  4RF9 A;  1FPY A;  1F1H A;  3JU6 A;  4AM1 A;  4LNN A;  2J1Q A;  1VRP A;  3DRE A;  3JQ3 A;  1P52 A;  4GVY A;  4BHL A;  1BG0 A;  3DRB A;  3L2E B;  4GVZ A;  1U6R A;  1P50 A;  1HTO A;  4LNF A;  4S0R A;  4XYC A;  2BVC A;  3M10 A;  2WGS A;  4LNO A;  2LGS A;  4BG4 B;  1RL9 A;  3L2D A;  4RF7 A;  3ZXR A;  3L2E A;  1CRK A;  1M15 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3DRBA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations