3L8NA

Crystal structure of a domain of brefeldin a-inhibited guanine nucleotide-exchange protein 2 (brefeldina-inhibited gep 2) from homo sapiens (human). northeast structural genomics consortium target id hr5562a
Total Genus 28
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
189
structure length
179
Chain Sequence
IKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKEVMYAYVDQLEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECLFASADTAYVLAYSIIMLTTDLPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A
rcsb
molecule tags Nucleotide-binding protein, metal-binding protein
source organism Homo sapiens
molecule keywords Brefeldin A-inhibited guanine nucleotide-exchange protein 2
total genus 28
structure length 179
sequence length 189
ec nomenclature
pdb deposition date 2009-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 3l8nA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 3l8nA02
4JMIA 1R8QE 1XSZA 4OIYA 4C0AA 1RE0B 4C7PA 1S9DE 1R8SE 4L5MA 2R0DA 3LTLA 1BC9A 4JWLA 1KU1A 1XT0B 1R8ME 4JMOA 3SWVA 4Z21A 3L8NA 4D7RA 4A4PA 4JXHA 1PBVA 4D7QA 2R09A
chains in the Genus database with same CATH superfamily
3ABSA 1HVDA 4C0AA 1SAVA 2RANA 4C7PA 1R4AE 1R8SE 4KN4X 4L5MA 1N44A 1I4AA 1W7BA 1AVCA 1BCYA 4FHRB 1XJLA 3ANYA 2OY9A 3BRXA 1DM5A 1HVGA 2QEZA 1YJ0A 1AXNA 2K6XA 4JK1X 1A8AA 1C1KA 1N41A 1BC1A 2ZHIA 4JMIA 1XSZA 2H0KA 1YCNA 4EVFA 1BCWA 3LTLA 4HREA 4MDVA 4KN7X 4MDUA 1XT0B 1LKVX 1R8ME 2ZHJA 2II2A 3L8NA 1AEIA 1HVFA 4JXHA 1M9IA 2H0MA 1ANXA 1BC3A 2IICA 2HSNA 1QC7A 2XO2A 2ZOCA 1AVRA 1RE0B 1S9DE 2HYVA 1W3WA 1ANNA 1BC0A 2R0DA 1ALAA 1HAKA 1BC9A 1YIIA 4Q2SA 4KMUX 1Q8DA 1YGMA 1W45A 3ABRA 2VXGA 3HJLA 1DK5A 3SOHB 4JMOA 1AOWA 3TW5A 3USYA 4FQ0C 2Q4CA 4D7QA 1A8BA 1N42A 2R09A 1MCXA 3AJCA 2H0LA 1R8QE 1HVEA 3AO0A 3ABQA 4OIYA 4EVHA 2IE7A 1ANWA 1UPTB 1G5NA 3USWA 4JWLA 1KU1A 1AVHA 2HYUA 1BCZA 1AIIA 1HM6A 3SWVA 3ABOA 4Z21A 4X9PA 2HYWA 4D7RA 2XO3A 4A4PA 1PBVA 1BO9A 1N00A 2IE6A
chains in the Genus database with same CATH topology
2HSNA 4JMIA 1R8QE 1XSZA 1QC7A 4OIYA 4C0AA 1RE0B 4C7PA 1S9DE 1R8SE 4KN4X 4L5MA 2R0DA 3LTLA 1BC9A 4KMUX 1Q8DA 3USWA 4JWLA 1KU1A 4KN7X 3HJLA 1XT0B 1LKVX 4FHRB 1R8ME 3SOHB 4JMOA 3SWVA 4Z21A 3L8NA 3TW5A 4D7RA 3USYA 4FQ0C 4A4PA 2K6XA 4JXHA 4JK1X 1PBVA 4D7QA 2R09A 3AJCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JMI A;  1R8Q E;  1XSZ A;  4OIY A;  4C0A A;  1RE0 B;  4C7P A;  1S9D E;  1R8S E;  4L5M A;  2R0D A;  3LTL A;  1BC9 A;  4JWL A;  1KU1 A;  1XT0 B;  1R8M E;  4JMO A;  3SWV A;  4Z21 A;  3L8N A;  4D7R A;  4A4P A;  4JXH A;  1PBV A;  4D7Q A;  2R09 A; 
#chains in the Genus database with same CATH topology
 3ABS A;  1HVD A;  4C0A A;  1SAV A;  2RAN A;  4C7P A;  1R4A E;  1R8S E;  4KN4 X;  4L5M A;  1N44 A;  1I4A A;  1W7B A;  1AVC A;  1BCY A;  4FHR B;  1XJL A;  3ANY A;  2OY9 A;  3BRX A;  1DM5 A;  1HVG A;  2QEZ A;  1YJ0 A;  1AXN A;  2K6X A;  4JK1 X;  1A8A A;  1C1K A;  1N41 A;  1BC1 A;  2ZHI A;  4JMI A;  1XSZ A;  2H0K A;  1YCN A;  4EVF A;  1BCW A;  3LTL A;  4HRE A;  4MDV A;  4KN7 X;  4MDU A;  1XT0 B;  1LKV X;  1R8M E;  2ZHJ A;  2II2 A;  3L8N A;  1AEI A;  1HVF A;  4JXH A;  1M9I A;  2H0M A;  1ANX A;  1BC3 A;  2IIC A;  2HSN A;  1QC7 A;  2XO2 A;  2ZOC A;  1AVR A;  1RE0 B;  1S9D E;  2HYV A;  1W3W A;  1ANN A;  1BC0 A;  2R0D A;  1ALA A;  1HAK A;  1BC9 A;  1YII A;  4Q2S A;  4KMU X;  1Q8D A;  1YGM A;  1W45 A;  3ABR A;  2VXG A;  3HJL A;  1DK5 A;  3SOH B;  4JMO A;  1AOW A;  3TW5 A;  3USY A;  4FQ0 C;  2Q4C A;  4D7Q A;  1A8B A;  1N42 A;  2R09 A;  1MCX A;  3AJC A;  2H0L A;  1R8Q E;  1HVE A;  3AO0 A;  3ABQ A;  4OIY A;  4EVH A;  2IE7 A;  1ANW A;  1UPT B;  1G5N A;  3USW A;  4JWL A;  1KU1 A;  1AVH A;  2HYU A;  1BCZ A;  1AII A;  1HM6 A;  3SWV A;  3ABO A;  4Z21 A;  4X9P A;  2HYW A;  4D7R A;  2XO3 A;  4A4P A;  1PBV A;  1BO9 A;  1N00 A;  2IE6 A; 
#chains in the Genus database with same CATH homology
 2HSN A;  4JMI A;  1R8Q E;  1XSZ A;  1QC7 A;  4OIY A;  4C0A A;  1RE0 B;  4C7P A;  1S9D E;  1R8S E;  4KN4 X;  4L5M A;  2R0D A;  3LTL A;  1BC9 A;  4KMU X;  1Q8D A;  3USW A;  4JWL A;  1KU1 A;  4KN7 X;  3HJL A;  1XT0 B;  1LKV X;  4FHR B;  1R8M E;  3SOH B;  4JMO A;  3SWV A;  4Z21 A;  3L8N A;  3TW5 A;  4D7R A;  3USY A;  4FQ0 C;  4A4P A;  2K6X A;  4JXH A;  4JK1 X;  1PBV A;  4D7Q A;  2R09 A;  3AJC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...