3L8NA

Crystal structure of a domain of brefeldin a-inhibited guanine nucleotide-exchange protein 2 (brefeldina-inhibited gep 2) from homo sapiens (human). northeast structural genomics consortium target id hr5562a
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
189
structure length
179
Chain Sequence
IKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKEVMYAYVDQLEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECLFASADTAYVLAYSIIMLTTDLPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A
rcsb
molecule tags Nucleotide-binding protein, metal-binding protein
source organism Homo sapiens
molecule keywords Brefeldin A-inhibited guanine nucleotide-exchange protein 2
total genus 28
structure length 179
sequence length 189
ec nomenclature
pdb deposition date 2009-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 3l8nA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 3l8nA02
1XT0B 2R0DA 1R8ME 3LTLA 3L8NA 4Z21A 2R09A 4A4PA 1S9DE 4JMOA 1KU1A 1R8QE 4C7PA 4L5MA 1XSZA 4D7QA 1PBVA 3SWVA 1R8SE 4OIYA 4JWLA 4JXHA 1BC9A 4C0AA 4JMIA 4D7RA 1RE0B
chains in the Genus database with same CATH superfamily
1HVGA 1R8ME 2ZOCA 1BC3A 4Z21A 1BCWA 2XO2A 4HREA 1BO9A 1ANNA 1YJ0A 3ABQA 1ALAA 2H0KA 2VXGA 3AO0A 1N41A 1I4AA 1LKVX 1AXNA 4EVHA 1N44A 4JWLA 1G5NA 1M9IA 4C0AA 4EVFA 2ZHIA 4D7RA 1RE0B 1SAVA 2QEZA 2IE7A 4FQ0C 1A8AA 3TW5A 2IICA 4MDUA 1XJLA 2R09A 1W45A 2H0MA 1S9DE 4JMOA 4X9PA 1R8QE 3ANYA 4C7PA 1BCYA 4D7QA 1HVEA 1AVHA 3ABOA 4JK1X 1ANXA 1MCXA 1BC9A 2ZHJA 4KMUX 3ABSA 1YGMA 1N42A 1YCNA 4JMIA 2HYWA 1UPTB 2HYUA 3USWA 1QC7A 1AVRA 1XT0B 3LTLA 3L8NA 2H0LA 3USYA 2HSNA 1HVDA 1KU1A 2K6XA 3ABRA 1DK5A 2Q4CA 1HM6A 1R4AE 2IE6A 1XSZA 1AOWA 4KN7X 1DM5A 3SWVA 1ANWA 4OIYA 3AJCA 2HYVA 1AEIA 3HJLA 1AVCA 1W3WA 2R0DA 1BCZA 1W7BA 2RANA 4A4PA 1AIIA 1HAKA 2OY9A 4Q2SA 4MDVA 2XO3A 1BC0A 4L5MA 1Q8DA 1PBVA 4FHRB 3SOHB 1R8SE 4JXHA 1N00A 1A8BA 2II2A 1BC1A 4KN4X 1YIIA 1C1KA 3BRXA 1HVFA
chains in the Genus database with same CATH topology
4FQ0C 3TW5A 1XT0B 2R0DA 1R8ME 3LTLA 3L8NA 4Z21A 2R09A 3USYA 2HSNA 4A4PA 1S9DE 4JMOA 1KU1A 2K6XA 1R8QE 4C7PA 4L5MA 1XSZA 1Q8DA 4D7QA 4KN7X 1LKVX 4JK1X 1PBVA 4FHRB 3SOHB 3SWVA 1R8SE 4OIYA 4JWLA 4JXHA 1BC9A 4KMUX 3AJCA 4KN4X 4C0AA 4JMIA 4D7RA 3HJLA 1RE0B 3USWA 1QC7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XT0 B;  2R0D A;  1R8M E;  3LTL A;  3L8N A;  4Z21 A;  2R09 A;  4A4P A;  1S9D E;  4JMO A;  1KU1 A;  1R8Q E;  4C7P A;  4L5M A;  1XSZ A;  4D7Q A;  1PBV A;  3SWV A;  1R8S E;  4OIY A;  4JWL A;  4JXH A;  1BC9 A;  4C0A A;  4JMI A;  4D7R A;  1RE0 B; 
#chains in the Genus database with same CATH topology
 1HVG A;  1R8M E;  2ZOC A;  1BC3 A;  4Z21 A;  1BCW A;  2XO2 A;  4HRE A;  1BO9 A;  1ANN A;  1YJ0 A;  3ABQ A;  1ALA A;  2H0K A;  2VXG A;  3AO0 A;  1N41 A;  1I4A A;  1LKV X;  1AXN A;  4EVH A;  1N44 A;  4JWL A;  1G5N A;  1M9I A;  4C0A A;  4EVF A;  2ZHI A;  4D7R A;  1RE0 B;  1SAV A;  2QEZ A;  2IE7 A;  4FQ0 C;  1A8A A;  3TW5 A;  2IIC A;  4MDU A;  1XJL A;  2R09 A;  1W45 A;  2H0M A;  1S9D E;  4JMO A;  4X9P A;  1R8Q E;  3ANY A;  4C7P A;  1BCY A;  4D7Q A;  1HVE A;  1AVH A;  3ABO A;  4JK1 X;  1ANX A;  1MCX A;  1BC9 A;  2ZHJ A;  4KMU X;  3ABS A;  1YGM A;  1N42 A;  1YCN A;  4JMI A;  2HYW A;  1UPT B;  2HYU A;  3USW A;  1QC7 A;  1AVR A;  1XT0 B;  3LTL A;  3L8N A;  2H0L A;  3USY A;  2HSN A;  1HVD A;  1KU1 A;  2K6X A;  3ABR A;  1DK5 A;  2Q4C A;  1HM6 A;  1R4A E;  2IE6 A;  1XSZ A;  1AOW A;  4KN7 X;  1DM5 A;  3SWV A;  1ANW A;  4OIY A;  3AJC A;  2HYV A;  1AEI A;  3HJL A;  1AVC A;  1W3W A;  2R0D A;  1BCZ A;  1W7B A;  2RAN A;  4A4P A;  1AII A;  1HAK A;  2OY9 A;  4Q2S A;  4MDV A;  2XO3 A;  1BC0 A;  4L5M A;  1Q8D A;  1PBV A;  4FHR B;  3SOH B;  1R8S E;  4JXH A;  1N00 A;  1A8B A;  2II2 A;  1BC1 A;  4KN4 X;  1YII A;  1C1K A;  3BRX A;  1HVF A; 
#chains in the Genus database with same CATH homology
 4FQ0 C;  3TW5 A;  1XT0 B;  2R0D A;  1R8M E;  3LTL A;  3L8N A;  4Z21 A;  2R09 A;  3USY A;  2HSN A;  4A4P A;  1S9D E;  4JMO A;  1KU1 A;  2K6X A;  1R8Q E;  4C7P A;  4L5M A;  1XSZ A;  1Q8D A;  4D7Q A;  4KN7 X;  1LKV X;  4JK1 X;  1PBV A;  4FHR B;  3SOH B;  3SWV A;  1R8S E;  4OIY A;  4JWL A;  4JXH A;  1BC9 A;  4KMU X;  3AJC A;  4KN4 X;  4C0A A;  4JMI A;  4D7R A;  3HJL A;  1RE0 B;  3USW A;  1QC7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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