3L8N | Genus

Total Genus 28

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	28
sequence length	189
structure length	179
Chain Sequence	IKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKEVMYAYVDQLEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECLFASADTAYVLAYSIIMLTTDLPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 179 atoms

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179 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Nucleotide-binding protein, metal-binding protein
source organism	Homo sapiens
publication title	Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A rcsb
molecule keywords	Brefeldin A-inhibited guanine nucleotide-exchange protein 2
total genus	28
structure length	179
sequence length	189
ec nomenclature
pdb deposition date	2009-12-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01369	Sec7	Sec7 domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.220.20	Mainly Alpha	Orthogonal Bundle	Annexin V; domain 1	Annexin V; domain 1	3l8nA01
1.10.1000.11	Mainly Alpha	Orthogonal Bundle	Arf Nucleotide-binding Site Opener; domain 2	Arf Nucleotide-binding Site Opener,domain 2	3l8nA02

4D7RA 4C7PA 1PBVA 4L5MA 4JWLA 2R09A 4C0AA 4Z21A 4JXHA 4A4PA 1RE0B 4JMOA 4D7QA 3L8NA 1KU1A 1XSZA 1R8SE 1R8QE 2R0DA 1BC9A 1XT0B 4JMIA 1S9DE 3SWVA 1R8ME 3LTLA 4OIYA
chains in the Genus database with same CATH superfamily

1HVFA 2H0KA 1N41A 1HM6A 1YIIA 2VXGA 1HVEA 1BO9A 1AVCA 2ZOCA 4HREA 1W45A 1A8AA 3L8NA 4Q2SA 4X9PA 1ANXA 1R8SE 1BCYA 1BC9A 3HJLA 1QC7A 1AXNA 4EVHA 1AVRA 3AJCA 3LTLA 1BC1A 4EVFA 1W3WA 1C1KA 3USYA 2Q4CA 2IE7A 1ANWA 1N44A 1ALAA 3TW5A 3BRXA 3AO0A 2XO3A 4JWLA 4L5MA 1UPTB 1M9IA 1LKVX 2HYVA 4D7QA 1HVGA 1MCXA 1R4AE 2XO2A 1R8QE 4JK1X 2R0DA 1YJ0A 3ABOA 4KN4X 1BC0A 4FQ0C 1AEIA 1N00A 1S9DE 3SWVA 4D7RA 4C7PA 1A8BA 1SAVA 1BCZA 2II2A 1PBVA 1YGMA 4Z21A 4C0AA 1RE0B 2OY9A 1W7BA 1Q8DA 2ZHJA 3USWA 1I4AA 1KU1A 3ABRA 1ANNA 1XJLA 1HVDA 4MDUA 3ANYA 2HSNA 2H0LA 1DK5A 4KN7X 4OIYA 1BCWA 1YCNA 2K6XA 1HAKA 2IE6A 1AOWA 2HYWA 3ABQA 2R09A 1N42A 4JXHA 2QEZA 4A4PA 2RANA 4JMOA 1AVHA 1G5NA 1DM5A 1XSZA 1BC3A 1XT0B 2IICA 2H0MA 4FHRB 4JMIA 4KMUX 2ZHIA 1AIIA 1R8ME 4MDVA 3ABSA 2HYUA 3SOHB
chains in the Genus database with same CATH topology

4D7RA 3USYA 4C7PA 2K6XA 3TW5A 4OIYA 1PBVA 4L5MA 4JWLA 2R09A 4C0AA 4Z21A 4JXHA 4A4PA 1RE0B 4JMOA 1LKVX 4D7QA 1Q8DA 3USWA 3L8NA 1KU1A 1XSZA 1R8SE 1R8QE 4JK1X 2R0DA 1BC9A 1XT0B 4KN4X 3HJLA 4FHRB 4JMIA 1QC7A 4KMUX 4FQ0C 1S9DE 2HSNA 3SWVA 3AJCA 1R8ME 3LTLA 4KN7X 3SOHB
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4D7R A;  4C7P A;  1PBV A;  4L5M A;  4JWL A;  2R09 A;  4C0A A;  4Z21 A;  4JXH A;  4A4P A;  1RE0 B;  4JMO A;  4D7Q A;  3L8N A;  1KU1 A;  1XSZ A;  1R8S E;  1R8Q E;  2R0D A;  1BC9 A;  1XT0 B;  4JMI A;  1S9D E;  3SWV A;  1R8M E;  3LTL A;  4OIY A; 
#chains in the Genus database with same CATH topology
 1HVF A;  2H0K A;  1N41 A;  1HM6 A;  1YII A;  2VXG A;  1HVE A;  1BO9 A;  1AVC A;  2ZOC A;  4HRE A;  1W45 A;  1A8A A;  3L8N A;  4Q2S A;  4X9P A;  1ANX A;  1R8S E;  1BCY A;  1BC9 A;  3HJL A;  1QC7 A;  1AXN A;  4EVH A;  1AVR A;  3AJC A;  3LTL A;  1BC1 A;  4EVF A;  1W3W A;  1C1K A;  3USY A;  2Q4C A;  2IE7 A;  1ANW A;  1N44 A;  1ALA A;  3TW5 A;  3BRX A;  3AO0 A;  2XO3 A;  4JWL A;  4L5M A;  1UPT B;  1M9I A;  1LKV X;  2HYV A;  4D7Q A;  1HVG A;  1MCX A;  1R4A E;  2XO2 A;  1R8Q E;  4JK1 X;  2R0D A;  1YJ0 A;  3ABO A;  4KN4 X;  1BC0 A;  4FQ0 C;  1AEI A;  1N00 A;  1S9D E;  3SWV A;  4D7R A;  4C7P A;  1A8B A;  1SAV A;  1BCZ A;  2II2 A;  1PBV A;  1YGM A;  4Z21 A;  4C0A A;  1RE0 B;  2OY9 A;  1W7B A;  1Q8D A;  2ZHJ A;  3USW A;  1I4A A;  1KU1 A;  3ABR A;  1ANN A;  1XJL A;  1HVD A;  4MDU A;  3ANY A;  2HSN A;  2H0L A;  1DK5 A;  4KN7 X;  4OIY A;  1BCW A;  1YCN A;  2K6X A;  1HAK A;  2IE6 A;  1AOW A;  2HYW A;  3ABQ A;  2R09 A;  1N42 A;  4JXH A;  2QEZ A;  4A4P A;  2RAN A;  4JMO A;  1AVH A;  1G5N A;  1DM5 A;  1XSZ A;  1BC3 A;  1XT0 B;  2IIC A;  2H0M A;  4FHR B;  4JMI A;  4KMU X;  2ZHI A;  1AII A;  1R8M E;  4MDV A;  3ABS A;  2HYU A;  3SOH B; 
#chains in the Genus database with same CATH homology
 4D7R A;  3USY A;  4C7P A;  2K6X A;  3TW5 A;  4OIY A;  1PBV A;  4L5M A;  4JWL A;  2R09 A;  4C0A A;  4Z21 A;  4JXH A;  4A4P A;  1RE0 B;  4JMO A;  1LKV X;  4D7Q A;  1Q8D A;  3USW A;  3L8N A;  1KU1 A;  1XSZ A;  1R8S E;  1R8Q E;  4JK1 X;  2R0D A;  1BC9 A;  1XT0 B;  4KN4 X;  3HJL A;  4FHR B;  4JMI A;  1QC7 A;  4KMU X;  4FQ0 C;  1S9D E;  2HSN A;  3SWV A;  3AJC A;  1R8M E;  3LTL A;  4KN7 X;  3SOH B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3L8NA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations