3LN6A

Crystal structure of a bifunctional glutathione synthetase from streptococcus agalactiae
Total Genus 204
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
204
sequence length
747
structure length
743
Chain Sequence
DRLLQRSHSHLPILQATFGLERESLRIHQPTQRVAQTPHPKTLGSRNYHPYIQTDYSEPQLELITPIAKDSQEAIRFLKAISDVAGRSINHDEYLWPLSMPPKVREEDIQIAQLEDAFEYDYRKYLEKTYGKLIQSISGIHYNLGLGQELLTSLFELSQADNAIDFQNQLYMKLSQNFLRYRWLLTYLYGASPVAEEDFLDQKLNNPVRSLRNSHLGYVNHKDIRISYTSLKDYVNDLENAVKSGQAEKEFYSPVRLRGSKACRNYLEKGITYLEFRTFDLNPFSPIGITQETVDTVHLFLLALLWIDSHIDQDIKEANRLNDLIALSHPLEKLPNQAPVSDLVDAMQSVIQHFNLSPYYQDLLESVKRQIQSPELTVAGQLLEMIEGLSLETFGQRQGQIYHDYAWEAPYALKGYETMELSTQLLLFDVIQKGVNFEVLDEQDQFLKLWHNSHIEYVKNGNMTSKDNYIVPLAMANKVVTKKILDEKHFPTPFGDEFTDRKEALNYFSQIQDKPIVVKPKSTNFGLGISIFKTSANLASYEKAIDIAFTEDSAILVEEYIEGTEYRFFVLEGDCIAVLLRVAANVVGDGIHTISQLVKLKNQNPLRGYDHRSPLEVIELGEVEQLMLEQQGYTVNSIPPEGTKIELRRNSNISTGGDSIDVTNTMDPTYKQLAAEMAEAMGAWVCGVDLIIPNATQAYSKDKKNATCIELNFNPLMYMHTYCQEGPGQSITPRILAKLFPEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structures of two bifunctional gamma-Glutamate-cysteine Ligase/Glutathione synthetases (GshF) reveal a novel hybrid ATP-grasp fold
rcsb
molecule tags Ligase
source organism Streptococcus agalactiae serogroup v
molecule keywords Glutathione biosynthesis bifunctional protein gshAB
total genus 204
structure length 743
sequence length 747
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2010-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01071 GARS_A Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
A PF04262 Glu_cys_ligase Glutamate-cysteine ligase
A PF18419 ATP-grasp_6 ATP-grasp-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 3ln6A01
1VA6A 3LN6A 1TT4A 1R8GA 3NZTA 2D32A 2D33A 2GWCA 3LN7A 1V4GA 2GWDA
chains in the Genus database with same CATH superfamily
4ACFA 4GVYA 1U6RA 4HPPA 4Q2RA 2LGSA 2J1QA 4S0RA 1P52A 3DREA 2OJWA 4BG4B 1R8GA 2D33A 4BHLA 3L2EB 2CRKA 4LNKA 1G0WA 3ZXVA 3FKYA 1CRKA 4RF9A 2BVCA 4BAXA 1V4GA 1F52A 1VRPA 3L2DA 3JU6A 2D32A 4AM1A 2GLSA 2UU7A 3LVVA 2WHIA 4RF6A 2GWDA 4S17A 1SD0A 3LN6A 3M10A 3JU5A 4LNOA 1VA6A 1HTOA 2D3AA 3JQ3A 4RF7A 1M15A 3DRBA 4XYCA 3ZXRA 4GW2A 3IG5A 1QK1A 3B6RA 1I0EA 5J9AA 1TT4A 2QC8A 3NZTA 3NG0A 2D3BA 4LNFA 1F1HA 1FPYA 3LN7A 1RL9A 4Z9MA 1LGRA 1P50A 4GW0A 1BG0A 4LNNA 1HTQA 3JPZA 3LVWA 4RF8A 4LNIA 1QH4A 2WGSA 4BG4A 4GVZA 2D3CA 5J99A 2GWCA 3L2EA 3IG8A
chains in the Genus database with same CATH topology
2D3BA 3LN6A 3FKYA 3LN7A 1VA6A 4BAXA 2D3AA 1V4GA 3NZTA 2OJWA 3IG5A 1R8GA 2D32A 2D33A 3LVWA 1TT4A 2UU7A 2QC8A 2D3CA 3LVVA 2GWCA 2GWDA 3IG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VA6 A;  3LN6 A;  1TT4 A;  1R8G A;  3NZT A;  2D32 A;  2D33 A;  2GWC A;  3LN7 A;  1V4G A;  2GWD A; 
#chains in the Genus database with same CATH topology
 4ACF A;  4GVY A;  1U6R A;  4HPP A;  4Q2R A;  2LGS A;  2J1Q A;  4S0R A;  1P52 A;  3DRE A;  2OJW A;  4BG4 B;  1R8G A;  2D33 A;  4BHL A;  3L2E B;  2CRK A;  4LNK A;  1G0W A;  3ZXV A;  3FKY A;  1CRK A;  4RF9 A;  2BVC A;  4BAX A;  1V4G A;  1F52 A;  1VRP A;  3L2D A;  3JU6 A;  2D32 A;  4AM1 A;  2GLS A;  2UU7 A;  3LVV A;  2WHI A;  4RF6 A;  2GWD A;  4S17 A;  1SD0 A;  3LN6 A;  3M10 A;  3JU5 A;  4LNO A;  1VA6 A;  1HTO A;  2D3A A;  3JQ3 A;  4RF7 A;  1M15 A;  3DRB A;  4XYC A;  3ZXR A;  4GW2 A;  3IG5 A;  1QK1 A;  3B6R A;  1I0E A;  5J9A A;  1TT4 A;  2QC8 A;  3NZT A;  3NG0 A;  2D3B A;  4LNF A;  1F1H A;  1FPY A;  3LN7 A;  1RL9 A;  4Z9M A;  1LGR A;  1P50 A;  4GW0 A;  1BG0 A;  4LNN A;  1HTQ A;  3JPZ A;  3LVW A;  4RF8 A;  4LNI A;  1QH4 A;  2WGS A;  4BG4 A;  4GVZ A;  2D3C A;  5J99 A;  2GWC A;  3L2E A;  3IG8 A; 
#chains in the Genus database with same CATH homology
 2D3B A;  3LN6 A;  3FKY A;  3LN7 A;  1VA6 A;  4BAX A;  2D3A A;  1V4G A;  3NZT A;  2OJW A;  3IG5 A;  1R8G A;  2D32 A;  2D33 A;  3LVW A;  1TT4 A;  2UU7 A;  2QC8 A;  2D3C A;  3LVV A;  2GWC A;  2GWD A;  3IG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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