3ORGA

Crystal structure of a eukaryotic clc transporter
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
623
structure length
534
Chain Sequence
SLMYLLRLVCFLTLLGVTAALFIFAVDLAVHGLEELRMKISRLAGRFAGYILYVVSGVALCLLSTFWCAVLSTEAEGSGLPQMKSILSGFYDKMRSALELRVLFAKALGLICAIGGGLPVGWEGPNVHIACIIAHQFYRLGVFKELCTDRALRLQTLAAACAVGLASSFGAPLGGVLYSIETIASFYLVQAFWKGVLSALSGAIVYELDVSRTQTLLYAILGALMGVLGALFIRCVRSIYELRMRHYPGTNRYFLVGVVALFASALQYPFPRATINDLFKAVTELILMPIIKFILVALSIGLPLPAGVFVPSFLIGAGFGRLYGELMRVVFGNAIVPGSYAVVGAAAFTAGVTRALSCAVIIFEVTGQIRHLVPVLISVLLAVIVGNAFNRSLYETLVLMKHLPYMPILRRDRSPEMTAREIMHPIEGEPHLFPDSEPQHIKGILEKFPNRLVFPVIDANGYLLGAISRKEIVDRLQHVVVPCDVSPIVVTSYSLVRQLHFLFVMLMPSMIYVTERGKLVGIVEREDVAYGYSN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle.
pubmed doi rcsb
molecule tags Transport protein
source organism Cyanidioschyzon merolae
molecule keywords CmCLC
total genus 170
structure length 534
sequence length 623
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-09-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 3orgA01
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 3orgA02
4P1GA 3KPDA 4ENEA 3L31A 5IIPA 3K6EA 3T4NC 2EXWA 2YVXA 3ND0A 3PC2A 2NYCA 3FWSA 3OI8A 3FWRA 2HLFA 4PCUA 4KJQA 3HF7A 4NOCA 3TE5C 4KJPA 1OTTA 3Q17A 2QR1E 5MMZA 4FTPA 1PVMA 4KK6A 3KXRA 2QH1A 4KK5A 2NYEA 5LXQA 2OOYE 1XKFA 3FNAA 4O9KA 2FEEA 3EJZA 4KJWA 2YZQA 4FXSA 3LQNA 4L3VA 1PBJA 3ORGA 2FECA 4IY3A 2OOXE 2RC3A 3PC4A 1OTUA 2RIHA 3LHHA 4IY2A 4KKBA 2HT4A 4COOA 3OCMA 4ESYB 2OUXA 2HT2A 2HT3A 4IYSA 4GQYA 2UV6A 4UUUA 4LOUA 4FG6A 3FHMA 4IY0A 4KK8A 5K24C 4GQWA 2QRCE 1KPLA 3GBYA 1YAVA 3I8NA 3KPCA 2D4ZA 2EXYA 3FV6A 3LV9A 2RIFA 3TDHC 5K25C 2EF7A 2UV7A 2YVYA 2H2PA 3EJYA 2ZY9A 3KPBA 2R9HA 3LFZA 4IY4A 2HTKA 4DQWA 2EMQA 2EZ0A 2YVZA 4MQXA 2QREE 1OTSA 5HD8A 5K22B 4KKAA 3KH5A 2QLVC 5KS7A 3NMOA 4FRYA 3DETA 2YZIA 4KK9A 4GQVA 4KKLA 2UV4A 4L0DA 3SL7A 3L2BA 5K23C 2UV5A 4P1OA 2PFIA 2H2SA 3PC3A 4KKCA 4L27A 3K2VA 2QRDE 1KPKA 2FEDA 4ESYA 4HG0A 3OCOA 4L28A 1Y5HA 2HTLA 1O50A 2O16A 3DDJA 2P9MA
chains in the Genus database with same CATH superfamily
4P1GA 3KPDA 4ENEA 3L31A 5IIPA 3K6EA 3T4NC 2EXWA 2YVXA 3ND0A 3PC2A 2NYCA 3FWSA 3OI8A 3FWRA 2HLFA 4PCUA 4KJQA 3HF7A 4NOCA 3TE5C 4KJPA 1OTTA 3Q17A 2QR1E 5MMZA 4FTPA 1PVMA 4KK6A 3KXRA 2QH1A 4KK5A 2NYEA 5LXQA 2OOYE 1XKFA 3FNAA 4O9KA 2FEEA 3EJZA 4KJWA 2YZQA 4FXSA 3LQNA 4L3VA 1PBJA 2J9LA 3ORGA 2FECA 4IY3A 2OOXE 2RC3A 3PC4A 1OTUA 2RIHA 3LHHA 4IY2A 4KKBA 2HT4A 4COOA 3OCMA 4ESYB 2OUXA 2HT2A 2HT3A 4IYSA 4GQYA 2UV6A 4UUUA 4LOUA 4FG6A 3FHMA 4IY0A 4KK8A 5K24C 4GQWA 2QRCE 1KPLA 3GBYA 1YAVA 3I8NA 3KPCA 2D4ZA 2EXYA 3FV6A 3LV9A 2RIFA 3TDHC 5K25C 2EF7A 2UV7A 2YVYA 2H2PA 3EJYA 2ZY9A 3KPBA 2R9HA 3LFZA 4IY4A 2HTKA 4DQWA 2EMQA 2EZ0A 2YVZA 4MQXA 2QREE 1OTSA 5HD8A 5K22B 4KKAA 3KH5A 2QLVC 5KS7A 3NMOA 4FRYA 3DETA 2YZIA 4KK9A 4GQVA 4KKLA 2UV4A 4L0DA 3SL7A 3L2BA 2JA3A 5K23C 2UV5A 4P1OA 2PFIA 2H2SA 3PC3A 4KKCA 4L27A 3K2VA 2QRDE 1KPKA 2FEDA 4ESYA 4HG0A 3OCOA 4L28A 1Y5HA 2HTLA 1O50A 2O16A 3DDJA 2P9MA
chains in the Genus database with same CATH topology
4P1GA 3KPDA 4ENEA 3L31A 5IIPA 3K6EA 3T4NC 2EXWA 2YVXA 3ND0A 3PC2A 2NYCA 3FWSA 3OI8A 3FWRA 2HLFA 4PCUA 4KJQA 3HF7A 4NOCA 3TE5C 4KJPA 1OTTA 3Q17A 2QR1E 5MMZA 4FTPA 1PVMA 4KK6A 3KXRA 2QH1A 4KK5A 2NYEA 5LXQA 2OOYE 1XKFA 3FNAA 4O9KA 2FEEA 3EJZA 4KJWA 2YZQA 4FXSA 3LQNA 4L3VA 1PBJA 2J9LA 3ORGA 2FECA 4IY3A 2OOXE 2RC3A 3PC4A 1OTUA 2RIHA 3LHHA 4IY2A 4KKBA 2HT4A 4COOA 3OCMA 4ESYB 2OUXA 2HT2A 2HT3A 4IYSA 4GQYA 2UV6A 4UUUA 4LOUA 4FG6A 3FHMA 4IY0A 4KK8A 5K24C 4GQWA 2QRCE 1KPLA 3GBYA 1YAVA 3I8NA 3KPCA 2D4ZA 2EXYA 3FV6A 3LV9A 2RIFA 3TDHC 5K25C 2EF7A 2UV7A 2YVYA 2H2PA 3EJYA 2ZY9A 3KPBA 2R9HA 3LFZA 4IY4A 2HTKA 4DQWA 2EMQA 2EZ0A 2YVZA 4MQXA 2QREE 1OTSA 5HD8A 5K22B 4KKAA 3KH5A 2QLVC 5KS7A 3NMOA 4FRYA 3DETA 2YZIA 4KK9A 4GQVA 4KKLA 2UV4A 4L0DA 3SL7A 3L2BA 2JA3A 5K23C 2UV5A 4P1OA 2PFIA 2H2SA 3PC3A 4KKCA 4L27A 3K2VA 2QRDE 1KPKA 2FEDA 4ESYA 4HG0A 3OCOA 4L28A 1Y5HA 2HTLA 1O50A 2O16A 3DDJA 2P9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1G A;  3KPD A;  4ENE A;  3L31 A;  5IIP A;  3K6E A;  3T4N C;  2EXW A;  2YVX A;  3ND0 A;  3PC2 A;  2NYC A;  3FWS A;  3OI8 A;  3FWR A;  2HLF A;  4PCU A;  4KJQ A;  3HF7 A;  4NOC A;  3TE5 C;  4KJP A;  1OTT A;  3Q17 A;  2QR1 E;  5MMZ A;  4FTP A;  1PVM A;  4KK6 A;  3KXR A;  2QH1 A;  4KK5 A;  2NYE A;  5LXQ A;  2OOY E;  1XKF A;  3FNA A;  4O9K A;  2FEE A;  3EJZ A;  4KJW A;  2YZQ A;  4FXS A;  3LQN A;  4L3V A;  1PBJ A;  3ORG A;  2FEC A;  4IY3 A;  2OOX E;  2RC3 A;  3PC4 A;  1OTU A;  2RIH A;  3LHH A;  4IY2 A;  4KKB A;  2HT4 A;  4COO A;  3OCM A;  4ESY B;  2OUX A;  2HT2 A;  2HT3 A;  4IYS A;  4GQY A;  2UV6 A;  4UUU A;  4LOU A;  4FG6 A;  3FHM A;  4IY0 A;  4KK8 A;  5K24 C;  4GQW A;  2QRC E;  1KPL A;  3GBY A;  1YAV A;  3I8N A;  3KPC A;  2D4Z A;  2EXY A;  3FV6 A;  3LV9 A;  2RIF A;  3TDH C;  5K25 C;  2EF7 A;  2UV7 A;  2YVY A;  2H2P A;  3EJY A;  2ZY9 A;  3KPB A;  2R9H A;  3LFZ A;  4IY4 A;  2HTK A;  4DQW A;  2EMQ A;  2EZ0 A;  2YVZ A;  4MQX A;  2QRE E;  1OTS A;  5HD8 A;  5K22 B;  4KKA A;  3KH5 A;  2QLV C;  5KS7 A;  3NMO A;  4FRY A;  3DET A;  2YZI A;  4KK9 A;  4GQV A;  4KKL A;  2UV4 A;  4L0D A;  3SL7 A;  3L2B A;  5K23 C;  2UV5 A;  4P1O A;  2PFI A;  2H2S A;  3PC3 A;  4KKC A;  4L27 A;  3K2V A;  2QRD E;  1KPK A;  2FED A;  4ESY A;  4HG0 A;  3OCO A;  4L28 A;  1Y5H A;  2HTL A;  1O50 A;  2O16 A;  3DDJ A;  2P9M A; 
#chains in the Genus database with same CATH topology
 4P1G A;  3KPD A;  4ENE A;  3L31 A;  5IIP A;  3K6E A;  3T4N C;  2EXW A;  2YVX A;  3ND0 A;  3PC2 A;  2NYC A;  3FWS A;  3OI8 A;  3FWR A;  2HLF A;  4PCU A;  4KJQ A;  3HF7 A;  4NOC A;  3TE5 C;  4KJP A;  1OTT A;  3Q17 A;  2QR1 E;  5MMZ A;  4FTP A;  1PVM A;  4KK6 A;  3KXR A;  2QH1 A;  4KK5 A;  2NYE A;  5LXQ A;  2OOY E;  1XKF A;  3FNA A;  4O9K A;  2FEE A;  3EJZ A;  4KJW A;  2YZQ A;  4FXS A;  3LQN A;  4L3V A;  1PBJ A;  2J9L A;  3ORG A;  2FEC A;  4IY3 A;  2OOX E;  2RC3 A;  3PC4 A;  1OTU A;  2RIH A;  3LHH A;  4IY2 A;  4KKB A;  2HT4 A;  4COO A;  3OCM A;  4ESY B;  2OUX A;  2HT2 A;  2HT3 A;  4IYS A;  4GQY A;  2UV6 A;  4UUU A;  4LOU A;  4FG6 A;  3FHM A;  4IY0 A;  4KK8 A;  5K24 C;  4GQW A;  2QRC E;  1KPL A;  3GBY A;  1YAV A;  3I8N A;  3KPC A;  2D4Z A;  2EXY A;  3FV6 A;  3LV9 A;  2RIF A;  3TDH C;  5K25 C;  2EF7 A;  2UV7 A;  2YVY A;  2H2P A;  3EJY A;  2ZY9 A;  3KPB A;  2R9H A;  3LFZ A;  4IY4 A;  2HTK A;  4DQW A;  2EMQ A;  2EZ0 A;  2YVZ A;  4MQX A;  2QRE E;  1OTS A;  5HD8 A;  5K22 B;  4KKA A;  3KH5 A;  2QLV C;  5KS7 A;  3NMO A;  4FRY A;  3DET A;  2YZI A;  4KK9 A;  4GQV A;  4KKL A;  2UV4 A;  4L0D A;  3SL7 A;  3L2B A;  2JA3 A;  5K23 C;  2UV5 A;  4P1O A;  2PFI A;  2H2S A;  3PC3 A;  4KKC A;  4L27 A;  3K2V A;  2QRD E;  1KPK A;  2FED A;  4ESY A;  4HG0 A;  3OCO A;  4L28 A;  1Y5H A;  2HTL A;  1O50 A;  2O16 A;  3DDJ A;  2P9M A; 
#chains in the Genus database with same CATH homology
 4P1G A;  3KPD A;  4ENE A;  3L31 A;  5IIP A;  3K6E A;  3T4N C;  2EXW A;  2YVX A;  3ND0 A;  3PC2 A;  2NYC A;  3FWS A;  3OI8 A;  3FWR A;  2HLF A;  4PCU A;  4KJQ A;  3HF7 A;  4NOC A;  3TE5 C;  4KJP A;  1OTT A;  3Q17 A;  2QR1 E;  5MMZ A;  4FTP A;  1PVM A;  4KK6 A;  3KXR A;  2QH1 A;  4KK5 A;  2NYE A;  5LXQ A;  2OOY E;  1XKF A;  3FNA A;  4O9K A;  2FEE A;  3EJZ A;  4KJW A;  2YZQ A;  4FXS A;  3LQN A;  4L3V A;  1PBJ A;  2J9L A;  3ORG A;  2FEC A;  4IY3 A;  2OOX E;  2RC3 A;  3PC4 A;  1OTU A;  2RIH A;  3LHH A;  4IY2 A;  4KKB A;  2HT4 A;  4COO A;  3OCM A;  4ESY B;  2OUX A;  2HT2 A;  2HT3 A;  4IYS A;  4GQY A;  2UV6 A;  4UUU A;  4LOU A;  4FG6 A;  3FHM A;  4IY0 A;  4KK8 A;  5K24 C;  4GQW A;  2QRC E;  1KPL A;  3GBY A;  1YAV A;  3I8N A;  3KPC A;  2D4Z A;  2EXY A;  3FV6 A;  3LV9 A;  2RIF A;  3TDH C;  5K25 C;  2EF7 A;  2UV7 A;  2YVY A;  2H2P A;  3EJY A;  2ZY9 A;  3KPB A;  2R9H A;  3LFZ A;  4IY4 A;  2HTK A;  4DQW A;  2EMQ A;  2EZ0 A;  2YVZ A;  4MQX A;  2QRE E;  1OTS A;  5HD8 A;  5K22 B;  4KKA A;  3KH5 A;  2QLV C;  5KS7 A;  3NMO A;  4FRY A;  3DET A;  2YZI A;  4KK9 A;  4GQV A;  4KKL A;  2UV4 A;  4L0D A;  3SL7 A;  3L2B A;  2JA3 A;  5K23 C;  2UV5 A;  4P1O A;  2PFI A;  2H2S A;  3PC3 A;  4KKC A;  4L27 A;  3K2V A;  2QRD E;  1KPK A;  2FED A;  4ESY A;  4HG0 A;  3OCO A;  4L28 A;  1Y5H A;  2HTL A;  1O50 A;  2O16 A;  3DDJ A;  2P9M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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