3SWVA

Crystal structure of a domain of brefeldin a-inhibited guanine nucleotide-exchange protein 2 (brefeldin a-inhibited gep 2) from homo sapiens (human), northeast structural genomics consortium target id hr5562a
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
192
structure length
188
Chain Sequence
FEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGTSVEDIAQFLHQEERLDSTQVGDFLGDSARFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKKIA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A
rcsb
molecule tags Metal binding protein
source organism Homo sapiens
molecule keywords Brefeldin A-inhibited guanine nucleotide-exchange protein 2
total genus 36
structure length 188
sequence length 192
ec nomenclature
pdb deposition date 2011-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 3swvA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 3swvA02
4JXHA 4D7QA 4C7PA 1PBVA 4D7RA 3LTLA 4A4PA 1R8SE 4Z21A 4JMOA 1R8ME 4JMIA 1KU1A 1R8QE 4JWLA 1BC9A 3SWVA 1RE0B 2R0DA 1S9DE 4L5MA 1XT0B 3L8NA 2R09A 4OIYA 1XSZA 4C0AA
chains in the Genus database with same CATH superfamily
1BC3A 1N00A 4JXHA 4D7QA 3HJLA 1YCNA 3ABQA 1BO9A 4D7RA 2HYUA 3LTLA 4FHRB 1W3WA 1HVDA 1N41A 3AJCA 4MDVA 1W7BA 2II2A 4JMIA 4JWLA 4MDUA 3ABOA 1MCXA 2IE6A 4X9PA 1AVHA 1ALAA 1SAVA 1S9DE 2VXGA 4KMUX 1AVCA 2RANA 1AXNA 4EVHA 2Q4CA 3ABRA 1BCZA 4A4PA 3TW5A 2IE7A 3USYA 4FQ0C 1HM6A 1AEIA 1UPTB 1R8QE 2ZHJA 2H0KA 3BRXA 1C1KA 1Q8DA 4HREA 1BC0A 1N42A 1XT0B 3L8NA 2ZHIA 3ANYA 3AO0A 2IICA 2OY9A 1XSZA 2ZOCA 1HVGA 4KN7X 2K6XA 1ANNA 1BC1A 1R8SE 1AVRA 4Z21A 1W45A 1XJLA 4JK1X 4JMOA 1A8BA 2HYVA 1BCWA 1R4AE 2HYWA 1AIIA 4KN4X 1RE0B 2XO3A 2HSNA 1BCYA 1HVFA 1HAKA 2XO2A 1ANWA 1YIIA 1N44A 1QC7A 1YJ0A 4C0AA 2QEZA 3SOHB 1AOWA 4C7PA 1I4AA 1G5NA 1HVEA 1PBVA 1M9IA 1R8ME 2H0LA 1KU1A 1YGMA 1BC9A 1DK5A 1DM5A 3SWVA 3ABSA 1A8AA 2R0DA 4EVFA 4L5MA 3USWA 1LKVX 4Q2SA 1ANXA 2R09A 4OIYA 2H0MA
chains in the Genus database with same CATH topology
4JXHA 3SOHB 4D7QA 3HJLA 4C7PA 4KN7X 2K6XA 1PBVA 3LTLA 4FHRB 4D7RA 4A4PA 1R8SE 3TW5A 4Z21A 4JK1X 3USYA 4JMOA 4FQ0C 3AJCA 1R8ME 4JMIA 1KU1A 1R8QE 4JWLA 1BC9A 4KN4X 3SWVA 1RE0B 2HSNA 1Q8DA 2R0DA 1S9DE 4L5MA 3USWA 1XT0B 3L8NA 1LKVX 4KMUX 2R09A 4OIYA 1QC7A 1XSZA 4C0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JXH A;  4D7Q A;  4C7P A;  1PBV A;  4D7R A;  3LTL A;  4A4P A;  1R8S E;  4Z21 A;  4JMO A;  1R8M E;  4JMI A;  1KU1 A;  1R8Q E;  4JWL A;  1BC9 A;  3SWV A;  1RE0 B;  2R0D A;  1S9D E;  4L5M A;  1XT0 B;  3L8N A;  2R09 A;  4OIY A;  1XSZ A;  4C0A A; 
#chains in the Genus database with same CATH topology
 1BC3 A;  1N00 A;  4JXH A;  4D7Q A;  3HJL A;  1YCN A;  3ABQ A;  1BO9 A;  4D7R A;  2HYU A;  3LTL A;  4FHR B;  1W3W A;  1HVD A;  1N41 A;  3AJC A;  4MDV A;  1W7B A;  2II2 A;  4JMI A;  4JWL A;  4MDU A;  3ABO A;  1MCX A;  2IE6 A;  4X9P A;  1AVH A;  1ALA A;  1SAV A;  1S9D E;  2VXG A;  4KMU X;  1AVC A;  2RAN A;  1AXN A;  4EVH A;  2Q4C A;  3ABR A;  1BCZ A;  4A4P A;  3TW5 A;  2IE7 A;  3USY A;  4FQ0 C;  1HM6 A;  1AEI A;  1UPT B;  1R8Q E;  2ZHJ A;  2H0K A;  3BRX A;  1C1K A;  1Q8D A;  4HRE A;  1BC0 A;  1N42 A;  1XT0 B;  3L8N A;  2ZHI A;  3ANY A;  3AO0 A;  2IIC A;  2OY9 A;  1XSZ A;  2ZOC A;  1HVG A;  4KN7 X;  2K6X A;  1ANN A;  1BC1 A;  1R8S E;  1AVR A;  4Z21 A;  1W45 A;  1XJL A;  4JK1 X;  4JMO A;  1A8B A;  2HYV A;  1BCW A;  1R4A E;  2HYW A;  1AII A;  4KN4 X;  1RE0 B;  2XO3 A;  2HSN A;  1BCY A;  1HVF A;  1HAK A;  2XO2 A;  1ANW A;  1YII A;  1N44 A;  1QC7 A;  1YJ0 A;  4C0A A;  2QEZ A;  3SOH B;  1AOW A;  4C7P A;  1I4A A;  1G5N A;  1HVE A;  1PBV A;  1M9I A;  1R8M E;  2H0L A;  1KU1 A;  1YGM A;  1BC9 A;  1DK5 A;  1DM5 A;  3SWV A;  3ABS A;  1A8A A;  2R0D A;  4EVF A;  4L5M A;  3USW A;  1LKV X;  4Q2S A;  1ANX A;  2R09 A;  4OIY A;  2H0M A; 
#chains in the Genus database with same CATH homology
 4JXH A;  3SOH B;  4D7Q A;  3HJL A;  4C7P A;  4KN7 X;  2K6X A;  1PBV A;  3LTL A;  4FHR B;  4D7R A;  4A4P A;  1R8S E;  3TW5 A;  4Z21 A;  4JK1 X;  3USY A;  4JMO A;  4FQ0 C;  3AJC A;  1R8M E;  4JMI A;  1KU1 A;  1R8Q E;  4JWL A;  1BC9 A;  4KN4 X;  3SWV A;  1RE0 B;  2HSN A;  1Q8D A;  2R0D A;  1S9D E;  4L5M A;  3USW A;  1XT0 B;  3L8N A;  1LKV X;  4KMU X;  2R09 A;  4OIY A;  1QC7 A;  1XSZ A;  4C0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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