4A4PA

Crystal structure of the sec7 domain from human cytohesin1
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
186
structure length
186
Chain Sequence
NKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Sec7 Domain from Human Cytohesin1
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords CYTOHESIN1
total genus 70
structure length 186
sequence length 186
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-10-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 4a4pA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 4a4pA02
4L5MA 4D7QA 1S9DE 3LTLA 4OIYA 1XT0B 4D7RA 3SWVA 4JMOA 1BC9A 1R8QE 2R09A 4JMIA 4A4PA 4C0AA 4JWLA 1PBVA 1KU1A 4JXHA 1R8SE 2R0DA 4Z21A 1R8ME 3L8NA 1RE0B 4C7PA 1XSZA
chains in the Genus database with same CATH superfamily
3ABOA 1S9DE 1YIIA 3LTLA 4OIYA 3ABRA 1AVHA 2ZHIA 1AEIA 1BC3A 4EVFA 1R4AE 3HJLA 4JMOA 1AVRA 2R09A 1BCZA 4JK1X 2VXGA 4KN7X 1HVDA 4JXHA 3USWA 1R8SE 1AOWA 1YJ0A 2XO3A 3L8NA 1RE0B 1BC1A 1I4AA 4L5MA 4MDVA 3USYA 4EVHA 1UPTB 2ZHJA 3AJCA 1ANWA 4FHRB 1HVGA 1HVFA 3AO0A 2XO2A 4JMIA 4A4PA 1W3WA 4JWLA 1QC7A 1HM6A 1KU1A 2OY9A 3BRXA 1XJLA 2IE7A 1BCWA 2ZOCA 1N42A 1BC0A 2HYVA 2H0KA 4KN4X 4D7QA 1AIIA 3ANYA 4MDUA 2Q4CA 1XT0B 1M9IA 3SWVA 3ABQA 1BC9A 2HYUA 1R8QE 1N41A 2II2A 2IICA 1BCYA 1HAKA 4X9PA 1YGMA 3SOHB 4C0AA 4Q2SA 1N44A 1AXNA 1SAVA 2HYWA 4Z21A 1W7BA 1R8ME 2H0MA 2QEZA 4C7PA 1BO9A 1XSZA 1ANNA 2K6XA 4FQ0C 2RANA 1A8BA 4D7RA 1AVCA 1DK5A 2HSNA 2IE6A 1DM5A 1Q8DA 1PBVA 1N00A 1G5NA 1YCNA 1ALAA 3TW5A 1ANXA 4HREA 2R0DA 2H0LA 1MCXA 3ABSA 1A8AA 1C1KA 1LKVX 1W45A 4KMUX 1HVEA
chains in the Genus database with same CATH topology
4KN4X 4L5MA 2K6XA 4D7QA 1S9DE 4FQ0C 3USYA 3LTLA 4OIYA 3AJCA 1XT0B 4FHRB 4D7RA 3HJLA 3SWVA 4JMOA 1BC9A 1R8QE 2HSNA 2R09A 4JMIA 4A4PA 4C0AA 3SOHB 4JWLA 1Q8DA 4JK1X 1PBVA 1QC7A 4KN7X 3TW5A 1KU1A 4JXHA 3USWA 1R8SE 2R0DA 4Z21A 1R8ME 3L8NA 1RE0B 1LKVX 4C7PA 4KMUX 1XSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L5M A;  4D7Q A;  1S9D E;  3LTL A;  4OIY A;  1XT0 B;  4D7R A;  3SWV A;  4JMO A;  1BC9 A;  1R8Q E;  2R09 A;  4JMI A;  4A4P A;  4C0A A;  4JWL A;  1PBV A;  1KU1 A;  4JXH A;  1R8S E;  2R0D A;  4Z21 A;  1R8M E;  3L8N A;  1RE0 B;  4C7P A;  1XSZ A; 
#chains in the Genus database with same CATH topology
 3ABO A;  1S9D E;  1YII A;  3LTL A;  4OIY A;  3ABR A;  1AVH A;  2ZHI A;  1AEI A;  1BC3 A;  4EVF A;  1R4A E;  3HJL A;  4JMO A;  1AVR A;  2R09 A;  1BCZ A;  4JK1 X;  2VXG A;  4KN7 X;  1HVD A;  4JXH A;  3USW A;  1R8S E;  1AOW A;  1YJ0 A;  2XO3 A;  3L8N A;  1RE0 B;  1BC1 A;  1I4A A;  4L5M A;  4MDV A;  3USY A;  4EVH A;  1UPT B;  2ZHJ A;  3AJC A;  1ANW A;  4FHR B;  1HVG A;  1HVF A;  3AO0 A;  2XO2 A;  4JMI A;  4A4P A;  1W3W A;  4JWL A;  1QC7 A;  1HM6 A;  1KU1 A;  2OY9 A;  3BRX A;  1XJL A;  2IE7 A;  1BCW A;  2ZOC A;  1N42 A;  1BC0 A;  2HYV A;  2H0K A;  4KN4 X;  4D7Q A;  1AII A;  3ANY A;  4MDU A;  2Q4C A;  1XT0 B;  1M9I A;  3SWV A;  3ABQ A;  1BC9 A;  2HYU A;  1R8Q E;  1N41 A;  2II2 A;  2IIC A;  1BCY A;  1HAK A;  4X9P A;  1YGM A;  3SOH B;  4C0A A;  4Q2S A;  1N44 A;  1AXN A;  1SAV A;  2HYW A;  4Z21 A;  1W7B A;  1R8M E;  2H0M A;  2QEZ A;  4C7P A;  1BO9 A;  1XSZ A;  1ANN A;  2K6X A;  4FQ0 C;  2RAN A;  1A8B A;  4D7R A;  1AVC A;  1DK5 A;  2HSN A;  2IE6 A;  1DM5 A;  1Q8D A;  1PBV A;  1N00 A;  1G5N A;  1YCN A;  1ALA A;  3TW5 A;  1ANX A;  4HRE A;  2R0D A;  2H0L A;  1MCX A;  3ABS A;  1A8A A;  1C1K A;  1LKV X;  1W45 A;  4KMU X;  1HVE A; 
#chains in the Genus database with same CATH homology
 4KN4 X;  4L5M A;  2K6X A;  4D7Q A;  1S9D E;  4FQ0 C;  3USY A;  3LTL A;  4OIY A;  3AJC A;  1XT0 B;  4FHR B;  4D7R A;  3HJL A;  3SWV A;  4JMO A;  1BC9 A;  1R8Q E;  2HSN A;  2R09 A;  4JMI A;  4A4P A;  4C0A A;  3SOH B;  4JWL A;  1Q8D A;  4JK1 X;  1PBV A;  1QC7 A;  4KN7 X;  3TW5 A;  1KU1 A;  4JXH A;  3USW A;  1R8S E;  2R0D A;  4Z21 A;  1R8M E;  3L8N A;  1RE0 B;  1LKV X;  4C7P A;  4KMU X;  1XSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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