4A4PA

Crystal structure of the sec7 domain from human cytohesin1
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
186
structure length
186
Chain Sequence
NKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Sec7 Domain from Human Cytohesin1
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords CYTOHESIN1
total genus 70
structure length 186
sequence length 186
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-10-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 4a4pA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 4a4pA02
4Z21A 4JMIA 3L8NA 4JXHA 4C0AA 4JWLA 1PBVA 1R8ME 1R8QE 1S9DE 4D7RA 2R0DA 4L5MA 1XSZA 4JMOA 3SWVA 3LTLA 4OIYA 4D7QA 4C7PA 1BC9A 4A4PA 2R09A 1XT0B 1R8SE 1KU1A 1RE0B
chains in the Genus database with same CATH superfamily
1ANXA 4JMIA 2HSNA 2Q4CA 1LKVX 3ABRA 3BRXA 1YIIA 1BCZA 1W45A 1BCYA 2OY9A 2II2A 3SWVA 2IE6A 4EVHA 3LTLA 3SOHB 1A8BA 2HYWA 1ANNA 3USWA 4A4PA 2R09A 3ABSA 1C1KA 1M9IA 1BO9A 1HVEA 4C0AA 1BC1A 2H0LA 1PBVA 1R8ME 4D7RA 1BCWA 1YCNA 4FHRB 1SAVA 2K6XA 1XJLA 2XO3A 1BC3A 1HVGA 4L5MA 1HAKA 1YJ0A 1W7BA 1HVDA 4OIYA 1YGMA 2ZHJA 3ABQA 1Q8DA 3USYA 1HVFA 1BC0A 1XT0B 1QC7A 1DK5A 1RE0B 4Z21A 1AEIA 1AVCA 3AJCA 3L8NA 2ZOCA 4JWLA 4EVFA 4HREA 1AIIA 1ANWA 3AO0A 1AVHA 2H0MA 1I4AA 2QEZA 3ABOA 2RANA 1N42A 2ZHIA 4JMOA 2H0KA 3ANYA 4X9PA 3TW5A 2IICA 4KMUX 1G5NA 4C7PA 1W3WA 1R8SE 1KU1A 4FQ0C 1AXNA 2HYUA 4JXHA 4KN7X 1MCXA 1R8QE 1S9DE 1N44A 1DM5A 2XO2A 4KN4X 1UPTB 1A8AA 1AVRA 1R4AE 2R0DA 1ALAA 2VXGA 1XSZA 4MDUA 1N41A 2HYVA 4D7QA 3HJLA 4MDVA 1BC9A 1HM6A 4Q2SA 1AOWA 1N00A 4JK1X 2IE7A
chains in the Genus database with same CATH topology
4FQ0C 4Z21A 3AJCA 4JMIA 3L8NA 2HSNA 4JXHA 4JWLA 4C0AA 1LKVX 4KN7X 1PBVA 1R8ME 1R8QE 1S9DE 4D7RA 4FHRB 4KN4X 2K6XA 2R0DA 1XSZA 4L5MA 4JMOA 3SWVA 3LTLA 3TW5A 3SOHB 4OIYA 4D7QA 3HJLA 1Q8DA 4KMUX 3USWA 4C7PA 1BC9A 4A4PA 3USYA 2R09A 1XT0B 1QC7A 1R8SE 4JK1X 1KU1A 1RE0B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z21 A;  4JMI A;  3L8N A;  4JXH A;  4C0A A;  4JWL A;  1PBV A;  1R8M E;  1R8Q E;  1S9D E;  4D7R A;  2R0D A;  4L5M A;  1XSZ A;  4JMO A;  3SWV A;  3LTL A;  4OIY A;  4D7Q A;  4C7P A;  1BC9 A;  4A4P A;  2R09 A;  1XT0 B;  1R8S E;  1KU1 A;  1RE0 B; 
#chains in the Genus database with same CATH topology
 1ANX A;  4JMI A;  2HSN A;  2Q4C A;  1LKV X;  3ABR A;  3BRX A;  1YII A;  1BCZ A;  1W45 A;  1BCY A;  2OY9 A;  2II2 A;  3SWV A;  2IE6 A;  4EVH A;  3LTL A;  3SOH B;  1A8B A;  2HYW A;  1ANN A;  3USW A;  4A4P A;  2R09 A;  3ABS A;  1C1K A;  1M9I A;  1BO9 A;  1HVE A;  4C0A A;  1BC1 A;  2H0L A;  1PBV A;  1R8M E;  4D7R A;  1BCW A;  1YCN A;  4FHR B;  1SAV A;  2K6X A;  1XJL A;  2XO3 A;  1BC3 A;  1HVG A;  4L5M A;  1HAK A;  1YJ0 A;  1W7B A;  1HVD A;  4OIY A;  1YGM A;  2ZHJ A;  3ABQ A;  1Q8D A;  3USY A;  1HVF A;  1BC0 A;  1XT0 B;  1QC7 A;  1DK5 A;  1RE0 B;  4Z21 A;  1AEI A;  1AVC A;  3AJC A;  3L8N A;  2ZOC A;  4JWL A;  4EVF A;  4HRE A;  1AII A;  1ANW A;  3AO0 A;  1AVH A;  2H0M A;  1I4A A;  2QEZ A;  3ABO A;  2RAN A;  1N42 A;  2ZHI A;  4JMO A;  2H0K A;  3ANY A;  4X9P A;  3TW5 A;  2IIC A;  4KMU X;  1G5N A;  4C7P A;  1W3W A;  1R8S E;  1KU1 A;  4FQ0 C;  1AXN A;  2HYU A;  4JXH A;  4KN7 X;  1MCX A;  1R8Q E;  1S9D E;  1N44 A;  1DM5 A;  2XO2 A;  4KN4 X;  1UPT B;  1A8A A;  1AVR A;  1R4A E;  2R0D A;  1ALA A;  2VXG A;  1XSZ A;  4MDU A;  1N41 A;  2HYV A;  4D7Q A;  3HJL A;  4MDV A;  1BC9 A;  1HM6 A;  4Q2S A;  1AOW A;  1N00 A;  4JK1 X;  2IE7 A; 
#chains in the Genus database with same CATH homology
 4FQ0 C;  4Z21 A;  3AJC A;  4JMI A;  3L8N A;  2HSN A;  4JXH A;  4JWL A;  4C0A A;  1LKV X;  4KN7 X;  1PBV A;  1R8M E;  1R8Q E;  1S9D E;  4D7R A;  4FHR B;  4KN4 X;  2K6X A;  2R0D A;  1XSZ A;  4L5M A;  4JMO A;  3SWV A;  3LTL A;  3TW5 A;  3SOH B;  4OIY A;  4D7Q A;  3HJL A;  1Q8D A;  4KMU X;  3USW A;  4C7P A;  1BC9 A;  4A4P A;  3USY A;  2R09 A;  1XT0 B;  1QC7 A;  1R8S E;  4JK1 X;  1KU1 A;  1RE0 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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