4GVZ | Genus

Total Genus 130

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	130
sequence length	356
structure length	356
Chain Sequence	VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs. pubmed doi rcsb
molecule keywords	Arginine kinase
molecule tags	Transferase
source organism	Limulus polyphemus
total genus	130
structure length	356
sequence length	356
ec nomenclature	ec 2.7.3.3: Arginine kinase.
pdb deposition date	2012-08-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00217	ATP-gua_Ptrans	ATP:guanido phosphotransferase, C-terminal catalytic domain
A	PF02807	ATP-gua_PtransN	ATP:guanido phosphotransferase, N-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.135.10	Mainly Alpha	Orthogonal Bundle	Transferase Creatine Kinase; Chain A, domain 1	ATP:guanido phosphotransferase, N-terminal domain	4gvzA01
3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase; Chain A, domain 2	Glutamine synthetase/guanido kinase, catalytic domain	4gvzA02

1QH4A 2CRKA 1P52A 4S17A 4RF8A 1U6RA 1I0EA 3B6RA 4GW0A 4BHLA 3JU5A 3ZXVA 1BG0A 4RF6A 1QK1A 1CRKA 4S0RA 3L2EA 3L2DA 1G0WA 4Q2RA 1VRPA 4ACFA 2BVCA 4LNKA 2J1QA 3JQ3A 4AM1A 1RL9A 3M10A 3DREA 2GLSA 3NG0A 3L2EB 3JU6A 4GW2A 4BG4A 4RF9A 5J99A 4LNIA 1F52A 4XYCA 3JPZA 4GVYA 5J9AA 4LNNA 4RF7A 1F1HA 1FPYA 1LGRA 4LNFA 3ZXRA 4GVZA 1HTOA 2WHIA 1HTQA 4LNOA 2LGSA 2WGSA 4Z9MA 3DRBA 4BG4B 1SD0A 1M15A 1P50A 4HPPA
chains in the Genus database with same CATH superfamily

2CRKA 3ZXVA 4RF6A 3L2EA 3L2DA 2D3BA 2BVCA 2D33A 4LNKA 4BG4A 2GWCA 4GVYA 4RF7A 1LGRA 1HTQA 2WHIA 2WGSA 4Z9MA 3DRBA 2D32A 4HPPA 3B6RA 4GW0A 3LVVA 1BG0A 1CRKA 2OJWA 4ACFA 2J1QA 1RL9A 2D3CA 2UU7A 4LNIA 3JPZA 3LVWA 5J9AA 4BAXA 1F1HA 1VA6A 3ZXRA 4GVZA 2LGSA 2D3AA 1M15A 1P50A 1QH4A 1P52A 4RF8A 1I0EA 1G0WA 4Q2RA 1VRPA 3NZTA 4AM1A 3M10A 3DREA 1R8GA 1V4GA 4RF9A 3IG8A 1SD0A 1F52A 4LNOA 4S17A 2GWDA 1U6RA 4BHLA 3JU5A 1QK1A 3LN7A 4S0RA 2QC8A 3IG5A 3JQ3A 2GLSA 3FKYA 3NG0A 3L2EB 3JU6A 4GW2A 5J99A 4XYCA 4LNNA 1TT4A 3LN6A 4LNFA 1HTOA 4BG4B 1FPYA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1QH4 A;  2CRK A;  1P52 A;  4S17 A;  4RF8 A;  1U6R A;  1I0E A;  3B6R A;  4GW0 A;  4BHL A;  3JU5 A;  3ZXV A;  1BG0 A;  4RF6 A;  1QK1 A;  1CRK A;  4S0R A;  3L2E A;  3L2D A;  1G0W A;  4Q2R A;  1VRP A;  4ACF A;  2BVC A;  4LNK A;  2J1Q A;  3JQ3 A;  4AM1 A;  1RL9 A;  3M10 A;  3DRE A;  2GLS A;  3NG0 A;  3L2E B;  3JU6 A;  4GW2 A;  4BG4 A;  4RF9 A;  5J99 A;  4LNI A;  1F52 A;  4XYC A;  3JPZ A;  4GVY A;  5J9A A;  4LNN A;  4RF7 A;  1F1H A;  1FPY A;  1LGR A;  4LNF A;  3ZXR A;  4GVZ A;  1HTO A;  2WHI A;  1HTQ A;  4LNO A;  2LGS A;  2WGS A;  4Z9M A;  3DRB A;  4BG4 B;  1SD0 A;  1M15 A;  1P50 A;  4HPP A; 
#chains in the Genus database with same CATH topology
 2CRK A;  3ZXV A;  4RF6 A;  3L2E A;  3L2D A;  2D3B A;  2BVC A;  2D33 A;  4LNK A;  4BG4 A;  2GWC A;  4GVY A;  4RF7 A;  1LGR A;  1HTQ A;  2WHI A;  2WGS A;  4Z9M A;  3DRB A;  2D32 A;  4HPP A;  3B6R A;  4GW0 A;  3LVV A;  1BG0 A;  1CRK A;  2OJW A;  4ACF A;  2J1Q A;  1RL9 A;  2D3C A;  2UU7 A;  4LNI A;  3JPZ A;  3LVW A;  5J9A A;  4BAX A;  1F1H A;  1VA6 A;  3ZXR A;  4GVZ A;  2LGS A;  2D3A A;  1M15 A;  1P50 A;  1QH4 A;  1P52 A;  4RF8 A;  1I0E A;  1G0W A;  4Q2R A;  1VRP A;  3NZT A;  4AM1 A;  3M10 A;  3DRE A;  1R8G A;  1V4G A;  4RF9 A;  3IG8 A;  1SD0 A;  1F52 A;  4LNO A;  4S17 A;  2GWD A;  1U6R A;  4BHL A;  3JU5 A;  1QK1 A;  3LN7 A;  4S0R A;  2QC8 A;  3IG5 A;  3JQ3 A;  2GLS A;  3FKY A;  3NG0 A;  3L2E B;  3JU6 A;  4GW2 A;  5J99 A;  4XYC A;  4LNN A;  1TT4 A;  3LN6 A;  4LNF A;  1HTO A;  4BG4 B;  1FPY A; 
#chains in the Genus database with same CATH homology
 1QH4 A;  2CRK A;  1P52 A;  4S17 A;  4RF8 A;  1U6R A;  1I0E A;  3B6R A;  4GW0 A;  4BHL A;  3JU5 A;  3ZXV A;  1BG0 A;  4RF6 A;  1QK1 A;  1CRK A;  4S0R A;  3L2E A;  3L2D A;  1G0W A;  4Q2R A;  1VRP A;  4ACF A;  2BVC A;  4LNK A;  2J1Q A;  3JQ3 A;  4AM1 A;  1RL9 A;  3M10 A;  3DRE A;  2GLS A;  3NG0 A;  3L2E B;  3JU6 A;  4GW2 A;  4BG4 A;  4RF9 A;  5J99 A;  4LNI A;  1F52 A;  4XYC A;  3JPZ A;  4GVY A;  5J9A A;  4LNN A;  4RF7 A;  1F1H A;  1FPY A;  1LGR A;  4LNF A;  3ZXR A;  4GVZ A;  1HTO A;  2WHI A;  1HTQ A;  4LNO A;  2LGS A;  2WGS A;  4Z9M A;  3DRB A;  4BG4 B;  1SD0 A;  1M15 A;  1P50 A;  4HPP A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4GVZA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations