4GW0A

Crystal structure of arginine kinase in complex with imino-l-ornithine, mgadp, and nitrate.
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
356
structure length
356
Chain Sequence
VDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs.
pubmed doi rcsb
molecule tags Transferase
source organism Limulus polyphemus
molecule keywords Arginine kinase
total genus 132
structure length 356
sequence length 356
ec nomenclature ec 2.7.3.3: Arginine kinase.
pdb deposition date 2012-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00217 ATP-gua_Ptrans ATP:guanido phosphotransferase, C-terminal catalytic domain
A PF02807 ATP-gua_PtransN ATP:guanido phosphotransferase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.135.10 Mainly Alpha Orthogonal Bundle Transferase Creatine Kinase; Chain A, domain 1 ATP:guanido phosphotransferase, N-terminal domain 4gw0A01
3.30.590.10 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Glutamine synthetase/guanido kinase, catalytic domain 4gw0A02
4GVYA 3B6RA 4S17A 2BVCA 4ACFA 1M15A 3DREA 4BG4B 3M10A 5J9AA 1BG0A 1F1HA 1P50A 1P52A 2CRKA 4S0RA 2WGSA 4LNOA 4HPPA 1U6RA 2J1QA 4Z9MA 1CRKA 3ZXVA 4RF7A 1FPYA 4AM1A 4RF8A 3NG0A 1QH4A 3ZXRA 1HTQA 3L2EA 4BHLA 1QK1A 1G0WA 3JU5A 2GLSA 4RF9A 5J99A 4RF6A 4Q2RA 1HTOA 3L2DA 4LNFA 1I0EA 3L2EB 1SD0A 1RL9A 1VRPA 3JPZA 4LNIA 2LGSA 3DRBA 2WHIA 4LNNA 4GW0A 4XYCA 3JU6A 4LNKA 4BG4A 3JQ3A 4GW2A 4GVZA 1LGRA 1F52A
chains in the Genus database with same CATH superfamily
3LVVA 2BVCA 4ACFA 1BG0A 1F1HA 1P52A 1R8GA 4HPPA 4AM1A 3ZXRA 4BHLA 1G0WA 2QC8A 4RF9A 4RF6A 3L2DA 1I0EA 3NZTA 1RL9A 2WHIA 4LNNA 3IG5A 3JU6A 4LNKA 2D3AA 1TT4A 3FKYA 2GWCA 2D33A 3LVWA 4S17A 2CRKA 1CRKA 2D32A 2D3BA 3JU5A 2OJWA 4LNFA 1HTOA 3JPZA 2LGSA 3LN7A 4BG4A 3JQ3A 2D3CA 4GVYA 2UU7A 1M15A 3M10A 4BAXA 2WGSA 1U6RA 2J1QA 1V4GA 3ZXVA 4RF8A 1HTQA 1QH4A 3LN6A 3L2EA 1QK1A 5J99A 4Q2RA 2GWDA 3DRBA 1VA6A 4GW0A 4XYCA 4GVZA 1F52A 3B6RA 3DREA 4BG4B 5J9AA 1P50A 4S0RA 4LNOA 4Z9MA 4RF7A 1FPYA 3NG0A 2GLSA 3L2EB 1SD0A 1VRPA 4LNIA 3IG8A 4GW2A 1LGRA
chains in the Genus database with same CATH topology
4GVYA 3B6RA 4S17A 2BVCA 4ACFA 1M15A 3DREA 4BG4B 3M10A 5J9AA 1BG0A 1F1HA 1P50A 1P52A 2CRKA 4S0RA 2WGSA 4LNOA 4HPPA 1U6RA 2J1QA 4Z9MA 1CRKA 3ZXVA 4RF7A 1FPYA 4AM1A 4RF8A 3NG0A 1QH4A 3ZXRA 1HTQA 3L2EA 4BHLA 1QK1A 1G0WA 3JU5A 2GLSA 4RF9A 5J99A 4RF6A 4Q2RA 1HTOA 3L2DA 4LNFA 1I0EA 3L2EB 1SD0A 1RL9A 1VRPA 3JPZA 4LNIA 2LGSA 3DRBA 2WHIA 4LNNA 4GW0A 4XYCA 3JU6A 4LNKA 4BG4A 3JQ3A 4GW2A 4GVZA 1LGRA 1F52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GVY A;  3B6R A;  4S17 A;  2BVC A;  4ACF A;  1M15 A;  3DRE A;  4BG4 B;  3M10 A;  5J9A A;  1BG0 A;  1F1H A;  1P50 A;  1P52 A;  2CRK A;  4S0R A;  2WGS A;  4LNO A;  4HPP A;  1U6R A;  2J1Q A;  4Z9M A;  1CRK A;  3ZXV A;  4RF7 A;  1FPY A;  4AM1 A;  4RF8 A;  3NG0 A;  1QH4 A;  3ZXR A;  1HTQ A;  3L2E A;  4BHL A;  1QK1 A;  1G0W A;  3JU5 A;  2GLS A;  4RF9 A;  5J99 A;  4RF6 A;  4Q2R A;  1HTO A;  3L2D A;  4LNF A;  1I0E A;  3L2E B;  1SD0 A;  1RL9 A;  1VRP A;  3JPZ A;  4LNI A;  2LGS A;  3DRB A;  2WHI A;  4LNN A;  4GW0 A;  4XYC A;  3JU6 A;  4LNK A;  4BG4 A;  3JQ3 A;  4GW2 A;  4GVZ A;  1LGR A;  1F52 A; 
#chains in the Genus database with same CATH topology
 3LVV A;  2BVC A;  4ACF A;  1BG0 A;  1F1H A;  1P52 A;  1R8G A;  4HPP A;  4AM1 A;  3ZXR A;  4BHL A;  1G0W A;  2QC8 A;  4RF9 A;  4RF6 A;  3L2D A;  1I0E A;  3NZT A;  1RL9 A;  2WHI A;  4LNN A;  3IG5 A;  3JU6 A;  4LNK A;  2D3A A;  1TT4 A;  3FKY A;  2GWC A;  2D33 A;  3LVW A;  4S17 A;  2CRK A;  1CRK A;  2D32 A;  2D3B A;  3JU5 A;  2OJW A;  4LNF A;  1HTO A;  3JPZ A;  2LGS A;  3LN7 A;  4BG4 A;  3JQ3 A;  2D3C A;  4GVY A;  2UU7 A;  1M15 A;  3M10 A;  4BAX A;  2WGS A;  1U6R A;  2J1Q A;  1V4G A;  3ZXV A;  4RF8 A;  1HTQ A;  1QH4 A;  3LN6 A;  3L2E A;  1QK1 A;  5J99 A;  4Q2R A;  2GWD A;  3DRB A;  1VA6 A;  4GW0 A;  4XYC A;  4GVZ A;  1F52 A;  3B6R A;  3DRE A;  4BG4 B;  5J9A A;  1P50 A;  4S0R A;  4LNO A;  4Z9M A;  4RF7 A;  1FPY A;  3NG0 A;  2GLS A;  3L2E B;  1SD0 A;  1VRP A;  4LNI A;  3IG8 A;  4GW2 A;  1LGR A; 
#chains in the Genus database with same CATH homology
 4GVY A;  3B6R A;  4S17 A;  2BVC A;  4ACF A;  1M15 A;  3DRE A;  4BG4 B;  3M10 A;  5J9A A;  1BG0 A;  1F1H A;  1P50 A;  1P52 A;  2CRK A;  4S0R A;  2WGS A;  4LNO A;  4HPP A;  1U6R A;  2J1Q A;  4Z9M A;  1CRK A;  3ZXV A;  4RF7 A;  1FPY A;  4AM1 A;  4RF8 A;  3NG0 A;  1QH4 A;  3ZXR A;  1HTQ A;  3L2E A;  4BHL A;  1QK1 A;  1G0W A;  3JU5 A;  2GLS A;  4RF9 A;  5J99 A;  4RF6 A;  4Q2R A;  1HTO A;  3L2D A;  4LNF A;  1I0E A;  3L2E B;  1SD0 A;  1RL9 A;  1VRP A;  3JPZ A;  4LNI A;  2LGS A;  3DRB A;  2WHI A;  4LNN A;  4GW0 A;  4XYC A;  3JU6 A;  4LNK A;  4BG4 A;  3JQ3 A;  4GW2 A;  4GVZ A;  1LGR A;  1F52 A; 
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similar chains in the Genus database (?% sequence similarity)
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