4MDVA

Crystal structure of calcium-bound annexin (sm)1
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
359
structure length
351
Chain Sequence
ISEFGITRSLIHSFDPHGKHYRPTIKPTTGFSASADAERLHRSMKGPGTNELAIINILARRTNYERQEICQSYKSLYKQDLKDDLKSDTSGDFRKVLCQLIVDTPYMLAKSLYYAMKGLGTNDRVLIEIFTTLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKETCGDYEYALLSLVQAERDDIPILQLKAIPDKGVNSIINHELAEADAKDLYASERRITRVICNRTPYQLYLTSEIYFKMYGKTLLEHIESETSGDYRKLLVAVLRYAIDRPSLIAEWLHDSMAGLGTKDYALMRLLITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSGDYRRTLCVLMGEIYN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
pubmed doi rcsb
molecule tags Metal binding protein
source organism Schistosoma mansoni
molecule keywords Annexin
total genus 136
structure length 351
sequence length 359
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA03
2RANA 1DK5A 1AEIA 1AOWA 1AVCA 1SAVA 1XJLA 1YCNA 2IICA 2ZHIA 2ZOCA 1A8AA 1BC1A 2HYUA 3BRXA 1BCYA 2HYVA 4EVHA 1AVRA 1ANXA 2XO3A 4EVFA 1DM5A 1BCWA 1I4AA 1MCXA 2IE7A 2Q4CA 2H0KA 2ZHJA 1AIIA 1W7BA 1W3WA 1BCZA 1G5NA 2II2A 4MDUA 1HVFA 2HYWA 2H0MA 1BC3A 1AXNA 1N41A 1BC0A 1HVEA 1AVHA 1BO9A 1HAKA 1YJ0A 2H0LA 1N42A 1YIIA 1M9IA 1HM6A 2XO2A 1HVDA 1N00A 2IE6A 1ANWA 1A8BA 4MDVA 1W45A 1ALAA 1HVGA 4HREA 1ANNA 1N44A 4X9PA
chains in the Genus database with same CATH superfamily
1XT0B 1DK5A 1AOWA 1AVCA 1R8QE 2ZOCA 1BC1A 3BRXA 4FHRB 1BCYA 2HYVA 1Q8DA 1KU1A 3ABOA 1AVRA 3AJCA 4EVHA 1C1KA 2R0DA 2XO3A 4EVFA 2Q4CA 3USWA 4Z21A 1W7BA 1PBVA 4JMOA 1BO9A 1AVHA 1M9IA 3ABQA 1HVDA 4L5MA 2OY9A 3LTLA 1BC9A 1XSZA 4KN4X 3TW5A 4HREA 1ANNA 4X9PA 3ABSA 4JMIA 1A8AA 4JWLA 4FQ0C 4JK1X 2QEZA 1DM5A 1I4AA 2IE7A 1RE0B 4MDUA 2HYWA 2H0MA 1BC3A 4C0AA 1N41A 1N42A 1YIIA 3USYA 4D7RA 1R8ME 3SWVA 3ABRA 2VXGA 4MDVA 1HVGA 2IE6A 1N44A 2RANA 1XJLA 1YCNA 4KN7X 2ZHIA 2HYUA 1ANXA 1R8SE 1BCWA 1MCXA 4KMUX 1AIIA 2II2A 1G5NA 3L8NA 1S9DE 2K6XA 1AXNA 1HVEA 1YGMA 1HAKA 1YJ0A 3AO0A 3HJLA 4A4PA 2XO2A 1N00A 1ANWA 1R4AE 3ANYA 4D7QA 1LKVX 1ALAA 1AEIA 2HSNA 1SAVA 2IICA 1UPTB 2H0KA 2ZHJA 4OIYA 1W3WA 1BCZA 1HVFA 1QC7A 4Q2SA 1BC0A 2R09A 3SOHB 2H0LA 1HM6A 4C7PA 1A8BA 1W45A 4JXHA
chains in the Genus database with same CATH topology
2RANA 1DK5A 1AEIA 1AOWA 1AVCA 1SAVA 1XJLA 1YCNA 2IICA 2ZHIA 2ZOCA 1A8AA 1BC1A 2HYUA 3BRXA 1BCYA 2HYVA 4EVHA 1AVRA 1ANXA 2XO3A 4EVFA 1DM5A 1BCWA 1I4AA 1MCXA 2IE7A 2Q4CA 2H0KA 2ZHJA 1AIIA 1W7BA 1W3WA 1BCZA 1G5NA 2II2A 4MDUA 1HVFA 2HYWA 2H0MA 1BC3A 1AXNA 1N41A 1BC0A 1HVEA 1AVHA 1BO9A 1HAKA 1YJ0A 2H0LA 1N42A 1YIIA 1M9IA 1HM6A 2XO2A 1HVDA 1N00A 2IE6A 1ANWA 1A8BA 4MDVA 1W45A 1ALAA 1HVGA 4HREA 1ANNA 1N44A 4X9PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RAN A;  1DK5 A;  1AEI A;  1AOW A;  1AVC A;  1SAV A;  1XJL A;  1YCN A;  2IIC A;  2ZHI A;  2ZOC A;  1A8A A;  1BC1 A;  2HYU A;  3BRX A;  1BCY A;  2HYV A;  4EVH A;  1AVR A;  1ANX A;  2XO3 A;  4EVF A;  1DM5 A;  1BCW A;  1I4A A;  1MCX A;  2IE7 A;  2Q4C A;  2H0K A;  2ZHJ A;  1AII A;  1W7B A;  1W3W A;  1BCZ A;  1G5N A;  2II2 A;  4MDU A;  1HVF A;  2HYW A;  2H0M A;  1BC3 A;  1AXN A;  1N41 A;  1BC0 A;  1HVE A;  1AVH A;  1BO9 A;  1HAK A;  1YJ0 A;  2H0L A;  1N42 A;  1YII A;  1M9I A;  1HM6 A;  2XO2 A;  1HVD A;  1N00 A;  2IE6 A;  1ANW A;  1A8B A;  4MDV A;  1W45 A;  1ALA A;  1HVG A;  4HRE A;  1ANN A;  1N44 A;  4X9P A; 
#chains in the Genus database with same CATH topology
 1XT0 B;  1DK5 A;  1AOW A;  1AVC A;  1R8Q E;  2ZOC A;  1BC1 A;  3BRX A;  4FHR B;  1BCY A;  2HYV A;  1Q8D A;  1KU1 A;  3ABO A;  1AVR A;  3AJC A;  4EVH A;  1C1K A;  2R0D A;  2XO3 A;  4EVF A;  2Q4C A;  3USW A;  4Z21 A;  1W7B A;  1PBV A;  4JMO A;  1BO9 A;  1AVH A;  1M9I A;  3ABQ A;  1HVD A;  4L5M A;  2OY9 A;  3LTL A;  1BC9 A;  1XSZ A;  4KN4 X;  3TW5 A;  4HRE A;  1ANN A;  4X9P A;  3ABS A;  4JMI A;  1A8A A;  4JWL A;  4FQ0 C;  4JK1 X;  2QEZ A;  1DM5 A;  1I4A A;  2IE7 A;  1RE0 B;  4MDU A;  2HYW A;  2H0M A;  1BC3 A;  4C0A A;  1N41 A;  1N42 A;  1YII A;  3USY A;  4D7R A;  1R8M E;  3SWV A;  3ABR A;  2VXG A;  4MDV A;  1HVG A;  2IE6 A;  1N44 A;  2RAN A;  1XJL A;  1YCN A;  4KN7 X;  2ZHI A;  2HYU A;  1ANX A;  1R8S E;  1BCW A;  1MCX A;  4KMU X;  1AII A;  2II2 A;  1G5N A;  3L8N A;  1S9D E;  2K6X A;  1AXN A;  1HVE A;  1YGM A;  1HAK A;  1YJ0 A;  3AO0 A;  3HJL A;  4A4P A;  2XO2 A;  1N00 A;  1ANW A;  1R4A E;  3ANY A;  4D7Q A;  1LKV X;  1ALA A;  1AEI A;  2HSN A;  1SAV A;  2IIC A;  1UPT B;  2H0K A;  2ZHJ A;  4OIY A;  1W3W A;  1BCZ A;  1HVF A;  1QC7 A;  4Q2S A;  1BC0 A;  2R09 A;  3SOH B;  2H0L A;  1HM6 A;  4C7P A;  1A8B A;  1W45 A;  4JXH A; 
#chains in the Genus database with same CATH homology
 2RAN A;  1DK5 A;  1AEI A;  1AOW A;  1AVC A;  1SAV A;  1XJL A;  1YCN A;  2IIC A;  2ZHI A;  2ZOC A;  1A8A A;  1BC1 A;  2HYU A;  3BRX A;  1BCY A;  2HYV A;  4EVH A;  1AVR A;  1ANX A;  2XO3 A;  4EVF A;  1DM5 A;  1BCW A;  1I4A A;  1MCX A;  2IE7 A;  2Q4C A;  2H0K A;  2ZHJ A;  1AII A;  1W7B A;  1W3W A;  1BCZ A;  1G5N A;  2II2 A;  4MDU A;  1HVF A;  2HYW A;  2H0M A;  1BC3 A;  1AXN A;  1N41 A;  1BC0 A;  1HVE A;  1AVH A;  1BO9 A;  1HAK A;  1YJ0 A;  2H0L A;  1N42 A;  1YII A;  1M9I A;  1HM6 A;  2XO2 A;  1HVD A;  1N00 A;  2IE6 A;  1ANW A;  1A8B A;  4MDV A;  1W45 A;  1ALA A;  1HVG A;  4HRE A;  1ANN A;  1N44 A;  4X9P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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