4MDVA

Crystal structure of calcium-bound annexin (sm)1
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
359
structure length
351
Chain Sequence
ISEFGITRSLIHSFDPHGKHYRPTIKPTTGFSASADAERLHRSMKGPGTNELAIINILARRTNYERQEICQSYKSLYKQDLKDDLKSDTSGDFRKVLCQLIVDTPYMLAKSLYYAMKGLGTNDRVLIEIFTTLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKETCGDYEYALLSLVQAERDDIPILQLKAIPDKGVNSIINHELAEADAKDLYASERRITRVICNRTPYQLYLTSEIYFKMYGKTLLEHIESETSGDYRKLLVAVLRYAIDRPSLIAEWLHDSMAGLGTKDYALMRLLITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSGDYRRTLCVLMGEIYN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Metal binding protein
source organism Schistosoma mansoni
publication title Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
pubmed doi rcsb
molecule keywords Annexin
total genus 136
structure length 351
sequence length 359
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00191 Annexin Annexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 4mdvA03
2XO3A 1AXNA 4MDUA 2H0LA 1AVRA 1YCNA 2ZHIA 1DK5A 1YJ0A 2ZOCA 2H0KA 4X9PA 1A8AA 1ANNA 2HYUA 1MCXA 1N00A 1A8BA 1ANXA 1I4AA 1BCZA 1AEIA 1N44A 3BRXA 1BCWA 1BCYA 1BO9A 1SAVA 1YIIA 1W3WA 4HREA 2HYWA 2XO2A 1HVFA 1G5NA 4MDVA 2IICA 1HAKA 1AIIA 1W45A 2IE6A 1N42A 2H0MA 1HM6A 1AVHA 1DM5A 1HVGA 1M9IA 1ALAA 1BC3A 1ANWA 1AVCA 2HYVA 1XJLA 2II2A 4EVHA 1HVEA 1HVDA 1AOWA 1BC0A 1W7BA 2IE7A 2RANA 2Q4CA 1N41A 2ZHJA 4EVFA 1BC1A
chains in the Genus database with same CATH superfamily
1AXNA 2OY9A 2H0LA 4JWLA 2ZOCA 4OIYA 1A8AA 4JMOA 1MCXA 1A8BA 1XSZA 1ANXA 2VXGA 4JMIA 1R4AE 4FQ0C 1SAVA 3USWA 1HVFA 1AIIA 1W45A 2H0MA 1Q8DA 2IICA 1HVGA 1PBVA 1BC0A 1W7BA 3ABSA 4Z21A 4C0AA 2XO3A 1R8QE 1YCNA 3ABOA 2ZHIA 1YJ0A 4X9PA 2H0KA 2HYUA 4A4PA 3LTLA 1BCZA 1BCYA 4Q2SA 3ABRA 1W3WA 4HREA 2R09A 1G5NA 4KN4X 1QC7A 1S9DE 1KU1A 3ANYA 3TW5A 4EVHA 2II2A 1XJLA 1HVDA 2RANA 3ABQA 1N41A 4D7QA 1BC1A 2ZHJA 3HJLA 3SWVA 1LKVX 4JXHA 2K6XA 1AEIA 1N44A 4L5MA 1BO9A 1UPTB 2HYWA 4MDVA 1HAKA 3USYA 1N42A 1AVHA 1DM5A 2R0DA 1ALAA 1ANWA 1AVCA 2IE7A 1AOWA 2Q4CA 3L8NA 1XT0B 2HSNA 4MDUA 1AVRA 2QEZA 1BC9A 1DK5A 1R8ME 1ANNA 4C7PA 1N00A 4KMUX 1I4AA 1RE0B 3AJCA 3BRXA 3AO0A 1BCWA 3SOHB 4JK1X 1YIIA 1C1KA 2XO2A 2IE6A 4FHRB 1HM6A 1R8SE 1M9IA 1BC3A 2HYVA 1HVEA 1YGMA 4EVFA 4KN7X 4D7RA
chains in the Genus database with same CATH topology
2XO3A 1AXNA 4MDUA 2H0LA 1AVRA 1YCNA 2ZHIA 1DK5A 1YJ0A 2ZOCA 2H0KA 4X9PA 1A8AA 1ANNA 2HYUA 1MCXA 1N00A 1A8BA 1ANXA 1I4AA 1BCZA 1AEIA 1N44A 3BRXA 1BCWA 1BCYA 1BO9A 1SAVA 1YIIA 1W3WA 4HREA 2HYWA 2XO2A 1HVFA 1G5NA 4MDVA 2IICA 1HAKA 1AIIA 1W45A 2IE6A 1N42A 2H0MA 1HM6A 1AVHA 1DM5A 1HVGA 1M9IA 1ALAA 1BC3A 1ANWA 1AVCA 2HYVA 1XJLA 2II2A 4EVHA 1HVEA 1HVDA 1AOWA 1BC0A 1W7BA 2IE7A 2RANA 2Q4CA 1N41A 2ZHJA 4EVFA 1BC1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XO3 A;  1AXN A;  4MDU A;  2H0L A;  1AVR A;  1YCN A;  2ZHI A;  1DK5 A;  1YJ0 A;  2ZOC A;  2H0K A;  4X9P A;  1A8A A;  1ANN A;  2HYU A;  1MCX A;  1N00 A;  1A8B A;  1ANX A;  1I4A A;  1BCZ A;  1AEI A;  1N44 A;  3BRX A;  1BCW A;  1BCY A;  1BO9 A;  1SAV A;  1YII A;  1W3W A;  4HRE A;  2HYW A;  2XO2 A;  1HVF A;  1G5N A;  4MDV A;  2IIC A;  1HAK A;  1AII A;  1W45 A;  2IE6 A;  1N42 A;  2H0M A;  1HM6 A;  1AVH A;  1DM5 A;  1HVG A;  1M9I A;  1ALA A;  1BC3 A;  1ANW A;  1AVC A;  2HYV A;  1XJL A;  2II2 A;  4EVH A;  1HVE A;  1HVD A;  1AOW A;  1BC0 A;  1W7B A;  2IE7 A;  2RAN A;  2Q4C A;  1N41 A;  2ZHJ A;  4EVF A;  1BC1 A; 
#chains in the Genus database with same CATH topology
 1AXN A;  2OY9 A;  2H0L A;  4JWL A;  2ZOC A;  4OIY A;  1A8A A;  4JMO A;  1MCX A;  1A8B A;  1XSZ A;  1ANX A;  2VXG A;  4JMI A;  1R4A E;  4FQ0 C;  1SAV A;  3USW A;  1HVF A;  1AII A;  1W45 A;  2H0M A;  1Q8D A;  2IIC A;  1HVG A;  1PBV A;  1BC0 A;  1W7B A;  3ABS A;  4Z21 A;  4C0A A;  2XO3 A;  1R8Q E;  1YCN A;  3ABO A;  2ZHI A;  1YJ0 A;  4X9P A;  2H0K A;  2HYU A;  4A4P A;  3LTL A;  1BCZ A;  1BCY A;  4Q2S A;  3ABR A;  1W3W A;  4HRE A;  2R09 A;  1G5N A;  4KN4 X;  1QC7 A;  1S9D E;  1KU1 A;  3ANY A;  3TW5 A;  4EVH A;  2II2 A;  1XJL A;  1HVD A;  2RAN A;  3ABQ A;  1N41 A;  4D7Q A;  1BC1 A;  2ZHJ A;  3HJL A;  3SWV A;  1LKV X;  4JXH A;  2K6X A;  1AEI A;  1N44 A;  4L5M A;  1BO9 A;  1UPT B;  2HYW A;  4MDV A;  1HAK A;  3USY A;  1N42 A;  1AVH A;  1DM5 A;  2R0D A;  1ALA A;  1ANW A;  1AVC A;  2IE7 A;  1AOW A;  2Q4C A;  3L8N A;  1XT0 B;  2HSN A;  4MDU A;  1AVR A;  2QEZ A;  1BC9 A;  1DK5 A;  1R8M E;  1ANN A;  4C7P A;  1N00 A;  4KMU X;  1I4A A;  1RE0 B;  3AJC A;  3BRX A;  3AO0 A;  1BCW A;  3SOH B;  4JK1 X;  1YII A;  1C1K A;  2XO2 A;  2IE6 A;  4FHR B;  1HM6 A;  1R8S E;  1M9I A;  1BC3 A;  2HYV A;  1HVE A;  1YGM A;  4EVF A;  4KN7 X;  4D7R A; 
#chains in the Genus database with same CATH homology
 2XO3 A;  1AXN A;  4MDU A;  2H0L A;  1AVR A;  1YCN A;  2ZHI A;  1DK5 A;  1YJ0 A;  2ZOC A;  2H0K A;  4X9P A;  1A8A A;  1ANN A;  2HYU A;  1MCX A;  1N00 A;  1A8B A;  1ANX A;  1I4A A;  1BCZ A;  1AEI A;  1N44 A;  3BRX A;  1BCW A;  1BCY A;  1BO9 A;  1SAV A;  1YII A;  1W3W A;  4HRE A;  2HYW A;  2XO2 A;  1HVF A;  1G5N A;  4MDV A;  2IIC A;  1HAK A;  1AII A;  1W45 A;  2IE6 A;  1N42 A;  2H0M A;  1HM6 A;  1AVH A;  1DM5 A;  1HVG A;  1M9I A;  1ALA A;  1BC3 A;  1ANW A;  1AVC A;  2HYV A;  1XJL A;  2II2 A;  4EVH A;  1HVE A;  1HVD A;  1AOW A;  1BC0 A;  1W7B A;  2IE7 A;  2RAN A;  2Q4C A;  1N41 A;  2ZHJ A;  4EVF A;  1BC1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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