4Q2R | Genus

Total Genus 128

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	128
sequence length	376
structure length	366
Chain Sequence	SHNLKLRFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGHPYIMTVGCVAGDEESYDVFKELFDPIIEDRHGGYKPTDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFPEVLKRLRLQKRGGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 366 atoms

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366 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structural Proteomics From Crude Native Rod Outer Segments rcsb
molecule keywords	Creatine kinase B-type
molecule tags	Transferase
total genus	128
structure length	366
sequence length	376
chains with identical sequence	B
ec nomenclature	ec 2.7.3.2: Creatine kinase.
pdb deposition date	2014-04-09

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00217	ATP-gua_Ptrans	ATP:guanido phosphotransferase, C-terminal catalytic domain
A	PF02807	ATP-gua_PtransN	ATP:guanido phosphotransferase, N-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.135.10	Mainly Alpha	Orthogonal Bundle	Transferase Creatine Kinase; Chain A, domain 1	ATP:guanido phosphotransferase, N-terminal domain	4q2rA01
3.30.590.10	Alpha Beta	2-Layer Sandwich	Creatine Kinase; Chain A, domain 2	Glutamine synthetase/guanido kinase, catalytic domain	4q2rA02

4RF6A 1U6RA 4GVZA 1SD0A 4GW0A 4AM1A 1I0EA 1F52A 4LNOA 1M15A 3JPZA 4Z9MA 1P52A 1QK1A 4BHLA 2BVCA 4Q2RA 2WGSA 4LNIA 1HTOA 4S17A 2CRKA 3L2EA 2WHIA 3JQ3A 4BG4B 3JU5A 1QH4A 3M10A 4LNNA 1CRKA 1VRPA 3JU6A 4RF8A 4RF7A 1G0WA 1HTQA 1F1HA 4HPPA 4LNKA 3ZXVA 4RF9A 4XYCA 4ACFA 3ZXRA 4GVYA 3DRBA 5J9AA 3NG0A 4GW2A 4BG4A 1RL9A 2LGSA 1P50A 4S0RA 3B6RA 3DREA 3L2EB 1BG0A 2J1QA 2GLSA 5J99A 1LGRA 4LNFA 1FPYA 3L2DA
chains in the Genus database with same CATH superfamily

1F52A 1M15A 4LNIA 4Q2RA 2CRKA 3L2EA 3JU6A 4RF7A 4LNKA 3ZXVA 1VA6A 4BG4A 3FKYA 1P50A 3NZTA 2J1QA 4GVZA 4GW0A 1I0EA 2D32A 3JPZA 2UU7A 3JQ3A 3LVWA 4RF8A 1TT4A 4RF9A 4BAXA 3L2EB 1BG0A 2GLSA 3LN6A 1LGRA 1FPYA 2GWCA 4RF6A 1SD0A 2WGSA 4Z9MA 1QK1A 4S17A 2WHIA 2D3AA 4BG4B 4LNNA 1HTQA 2D3CA 4XYCA 1R8GA 4ACFA 4GVYA 3IG8A 3DRBA 5J9AA 3LVVA 1RL9A 2LGSA 3IG5A 4S0RA 3B6RA 3LN7A 3DREA 2GWDA 5J99A 2QC8A 1V4GA 3L2DA 1U6RA 4AM1A 4LNOA 1P52A 4BHLA 2BVCA 1HTOA 2OJWA 3JU5A 1QH4A 3M10A 1CRKA 1VRPA 1G0WA 1F1HA 4HPPA 2D33A 3NG0A 4GW2A 2D3BA 4LNFA 3ZXRA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4RF6 A;  1U6R A;  4GVZ A;  1SD0 A;  4GW0 A;  4AM1 A;  1I0E A;  1F52 A;  4LNO A;  1M15 A;  3JPZ A;  4Z9M A;  1P52 A;  1QK1 A;  4BHL A;  2BVC A;  4Q2R A;  2WGS A;  4LNI A;  1HTO A;  4S17 A;  2CRK A;  3L2E A;  2WHI A;  3JQ3 A;  4BG4 B;  3JU5 A;  1QH4 A;  3M10 A;  4LNN A;  1CRK A;  1VRP A;  3JU6 A;  4RF8 A;  4RF7 A;  1G0W A;  1HTQ A;  1F1H A;  4HPP A;  4LNK A;  3ZXV A;  4RF9 A;  4XYC A;  4ACF A;  3ZXR A;  4GVY A;  3DRB A;  5J9A A;  3NG0 A;  4GW2 A;  4BG4 A;  1RL9 A;  2LGS A;  1P50 A;  4S0R A;  3B6R A;  3DRE A;  3L2E B;  1BG0 A;  2J1Q A;  2GLS A;  5J99 A;  1LGR A;  4LNF A;  1FPY A;  3L2D A; 
#chains in the Genus database with same CATH topology
 1F52 A;  1M15 A;  4LNI A;  4Q2R A;  2CRK A;  3L2E A;  3JU6 A;  4RF7 A;  4LNK A;  3ZXV A;  1VA6 A;  4BG4 A;  3FKY A;  1P50 A;  3NZT A;  2J1Q A;  4GVZ A;  4GW0 A;  1I0E A;  2D32 A;  3JPZ A;  2UU7 A;  3JQ3 A;  3LVW A;  4RF8 A;  1TT4 A;  4RF9 A;  4BAX A;  3L2E B;  1BG0 A;  2GLS A;  3LN6 A;  1LGR A;  1FPY A;  2GWC A;  4RF6 A;  1SD0 A;  2WGS A;  4Z9M A;  1QK1 A;  4S17 A;  2WHI A;  2D3A A;  4BG4 B;  4LNN A;  1HTQ A;  2D3C A;  4XYC A;  1R8G A;  4ACF A;  4GVY A;  3IG8 A;  3DRB A;  5J9A A;  3LVV A;  1RL9 A;  2LGS A;  3IG5 A;  4S0R A;  3B6R A;  3LN7 A;  3DRE A;  2GWD A;  5J99 A;  2QC8 A;  1V4G A;  3L2D A;  1U6R A;  4AM1 A;  4LNO A;  1P52 A;  4BHL A;  2BVC A;  1HTO A;  2OJW A;  3JU5 A;  1QH4 A;  3M10 A;  1CRK A;  1VRP A;  1G0W A;  1F1H A;  4HPP A;  2D33 A;  3NG0 A;  4GW2 A;  2D3B A;  4LNF A;  3ZXR A; 
#chains in the Genus database with same CATH homology
 4RF6 A;  1U6R A;  4GVZ A;  1SD0 A;  4GW0 A;  4AM1 A;  1I0E A;  1F52 A;  4LNO A;  1M15 A;  3JPZ A;  4Z9M A;  1P52 A;  1QK1 A;  4BHL A;  2BVC A;  4Q2R A;  2WGS A;  4LNI A;  1HTO A;  4S17 A;  2CRK A;  3L2E A;  2WHI A;  3JQ3 A;  4BG4 B;  3JU5 A;  1QH4 A;  3M10 A;  4LNN A;  1CRK A;  1VRP A;  3JU6 A;  4RF8 A;  4RF7 A;  1G0W A;  1HTQ A;  1F1H A;  4HPP A;  4LNK A;  3ZXV A;  4RF9 A;  4XYC A;  4ACF A;  3ZXR A;  4GVY A;  3DRB A;  5J9A A;  3NG0 A;  4GW2 A;  4BG4 A;  1RL9 A;  2LGS A;  1P50 A;  4S0R A;  3B6R A;  3DRE A;  3L2E B;  1BG0 A;  2J1Q A;  2GLS A;  5J99 A;  1LGR A;  4LNF A;  1FPY A;  3L2D A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4Q2RA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations